2Y2DA

Crystal structure of ampd holoenzyme
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
179
structure length
179
Chain Sequence
MLLDEGWLAEARRVPSPHYDCRPDDENPSLLVVHNISLPPGEFGGPWIDALFTGTIDPNAHPYFAGIAHLRVSAHCLIRRDGEIVQYVPFDKRAWHAGVSSYQGRERCNDFSIGIELEGTDTLAYTDAQYQQLAAVTNALITRYPAIANNMTGHCNIAPERKTDPGPSFDWARFRALVT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Citrobacter freundii
publication title Crystal Structures of Bacterial Peptidoglycan Amidase Ampd and an Unprecedented Activation Mechanism.
pubmed doi rcsb
molecule keywords 1,6-ANHYDRO-N-ACETYLMURAMYL-L-ALANINE AMIDASE AMPD
total genus 55
structure length 179
sequence length 179
chains with identical sequence B, C
ec nomenclature ec 3.5.1.28: N-acetylmuramoyl-L-alanine amidase.
pdb deposition date 2010-12-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01510 Amidase_2 N-acetylmuramoyl-L-alanine amidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.80.10 Alpha Beta 3-Layer(aba) Sandwich Lysozyme-like Peptidoglycan recognition protein-like 2y2dA00
3RT4A 3LATA 3D2YA 1SK4A 4FNNA 4Q9EA 4BJ4A 3T39A 4GF9A 2R90A 4BXEA 4OLSA 4OPPA 2BH7A 4ZXMA 3UILA 1SK3A 3C2XA 3CG9A 1LBAA 3O4KA 3CORA 5CTVA 4BXDA 2Y2DA 3HMBA 3NW3A 4Q8SA 4KNKA 5E0BA 4BOLA 5DWFA 3QV4A 2AR3A 1AROL 2CB3A 2Y28A 1S2JA 3USXA 3NG4A 2F2LA 3OGXA 4X36A 2R2KA 1OHTA 2XZ4A 1SXRA 3RDRA 2Z9NA 3NNOA 4OUGA 3QJ1A 3T2VA 3UMQA 2Y2EA 2L47A 2Y2CA 2RKQA 4BXJA 3CXAA 4ORVA 1TWQA 1YB0A 2Y2BA 4IVVA 3EP1A 2EAVA 2EAXA 4BPAA 4KNLA 4Z8IA 3UMLA 2F2LX 1YCKA 1Z6IA 2WKXA 2XZ8A 1J3GA 3D2ZA 3TRUA 2APHA 3QS0A 5E0AA
chains in the Genus database with same CATH superfamily
3RT4A 3LATA 3D2YA 1SK4A 4FNNA 4Q9EA 4BJ4A 3T39A 4GF9A 2R90A 4BXEA 4OLSA 4OPPA 2BH7A 4ZXMA 3UILA 1SK3A 3C2XA 3CG9A 1LBAA 3O4KA 3CORA 5CTVA 4BXDA 2Y2DA 3HMBA 3NW3A 4Q8SA 4KNKA 5E0BA 4BOLA 5DWFA 3QV4A 2AR3A 1AROL 2CB3A 2Y28A 1S2JA 3USXA 3NG4A 2F2LA 3OGXA 4X36A 2R2KA 1OHTA 2XZ4A 1SXRA 3RDRA 2Z9NA 3NNOA 4OUGA 3QJ1A 3T2VA 3UMQA 2Y2EA 2L47A 2Y2CA 2RKQA 4BXJA 3CXAA 4ORVA 1TWQA 1YB0A 2Y2BA 4IVVA 3EP1A 2EAVA 2EAXA 4BPAA 4KNLA 4Z8IA 3UMLA 2F2LX 1YCKA 1Z6IA 2WKXA 2XZ8A 1J3GA 3D2ZA 3TRUA 2APHA 3QS0A 5E0AA
chains in the Genus database with same CATH topology
3RT4A 3LATA 3D2YA 1SK4A 4FNNA 4Q9EA 4BJ4A 3T39A 4GF9A 2R90A 4BXEA 4OLSA 4OPPA 2BH7A 4ZXMA 3UILA 1SK3A 3C2XA 3CG9A 1LBAA 3O4KA 3CORA 5CTVA 4BXDA 2Y2DA 3HMBA 3NW3A 4Q8SA 4KNKA 5E0BA 4BOLA 5DWFA 3QV4A 2AR3A 1AROL 2CB3A 2Y28A 1S2JA 3USXA 3NG4A 2F2LA 3OGXA 4X36A 2R2KA 1OHTA 2XZ4A 1SXRA 3RDRA 2Z9NA 3NNOA 4OUGA 3QJ1A 3T2VA 3UMQA 2Y2EA 2L47A 2Y2CA 2RKQA 4BXJA 3CXAA 4ORVA 1TWQA 1YB0A 2Y2BA 4IVVA 3EP1A 2EAVA 2EAXA 4BPAA 4KNLA 4Z8IA 3UMLA 2F2LX 1YCKA 1Z6IA 2WKXA 2XZ8A 1J3GA 3D2ZA 3TRUA 2APHA 3QS0A 5E0AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RT4 A;  3LAT A;  3D2Y A;  1SK4 A;  4FNN A;  4Q9E A;  4BJ4 A;  3T39 A;  4GF9 A;  2R90 A;  4BXE A;  4OLS A;  4OPP A;  2BH7 A;  4ZXM A;  3UIL A;  1SK3 A;  3C2X A;  3CG9 A;  1LBA A;  3O4K A;  3COR A;  5CTV A;  4BXD A;  2Y2D A;  3HMB A;  3NW3 A;  4Q8S A;  4KNK A;  5E0B A;  4BOL A;  5DWF A;  3QV4 A;  2AR3 A;  1ARO L;  2CB3 A;  2Y28 A;  1S2J A;  3USX A;  3NG4 A;  2F2L A;  3OGX A;  4X36 A;  2R2K A;  1OHT A;  2XZ4 A;  1SXR A;  3RDR A;  2Z9N A;  3NNO A;  4OUG A;  3QJ1 A;  3T2V A;  3UMQ A;  2Y2E A;  2L47 A;  2Y2C A;  2RKQ A;  4BXJ A;  3CXA A;  4ORV A;  1TWQ A;  1YB0 A;  2Y2B A;  4IVV A;  3EP1 A;  2EAV A;  2EAX A;  4BPA A;  4KNL A;  4Z8I A;  3UML A;  2F2L X;  1YCK A;  1Z6I A;  2WKX A;  2XZ8 A;  1J3G A;  3D2Z A;  3TRU A;  2APH A;  3QS0 A;  5E0A A; 
#chains in the Genus database with same CATH topology
 3RT4 A;  3LAT A;  3D2Y A;  1SK4 A;  4FNN A;  4Q9E A;  4BJ4 A;  3T39 A;  4GF9 A;  2R90 A;  4BXE A;  4OLS A;  4OPP A;  2BH7 A;  4ZXM A;  3UIL A;  1SK3 A;  3C2X A;  3CG9 A;  1LBA A;  3O4K A;  3COR A;  5CTV A;  4BXD A;  2Y2D A;  3HMB A;  3NW3 A;  4Q8S A;  4KNK A;  5E0B A;  4BOL A;  5DWF A;  3QV4 A;  2AR3 A;  1ARO L;  2CB3 A;  2Y28 A;  1S2J A;  3USX A;  3NG4 A;  2F2L A;  3OGX A;  4X36 A;  2R2K A;  1OHT A;  2XZ4 A;  1SXR A;  3RDR A;  2Z9N A;  3NNO A;  4OUG A;  3QJ1 A;  3T2V A;  3UMQ A;  2Y2E A;  2L47 A;  2Y2C A;  2RKQ A;  4BXJ A;  3CXA A;  4ORV A;  1TWQ A;  1YB0 A;  2Y2B A;  4IVV A;  3EP1 A;  2EAV A;  2EAX A;  4BPA A;  4KNL A;  4Z8I A;  3UML A;  2F2L X;  1YCK A;  1Z6I A;  2WKX A;  2XZ8 A;  1J3G A;  3D2Z A;  3TRU A;  2APH A;  3QS0 A;  5E0A A; 
#chains in the Genus database with same CATH homology
 3RT4 A;  3LAT A;  3D2Y A;  1SK4 A;  4FNN A;  4Q9E A;  4BJ4 A;  3T39 A;  4GF9 A;  2R90 A;  4BXE A;  4OLS A;  4OPP A;  2BH7 A;  4ZXM A;  3UIL A;  1SK3 A;  3C2X A;  3CG9 A;  1LBA A;  3O4K A;  3COR A;  5CTV A;  4BXD A;  2Y2D A;  3HMB A;  3NW3 A;  4Q8S A;  4KNK A;  5E0B A;  4BOL A;  5DWF A;  3QV4 A;  2AR3 A;  1ARO L;  2CB3 A;  2Y28 A;  1S2J A;  3USX A;  3NG4 A;  2F2L A;  3OGX A;  4X36 A;  2R2K A;  1OHT A;  2XZ4 A;  1SXR A;  3RDR A;  2Z9N A;  3NNO A;  4OUG A;  3QJ1 A;  3T2V A;  3UMQ A;  2Y2E A;  2L47 A;  2Y2C A;  2RKQ A;  4BXJ A;  3CXA A;  4ORV A;  1TWQ A;  1YB0 A;  2Y2B A;  4IVV A;  3EP1 A;  2EAV A;  2EAX A;  4BPA A;  4KNL A;  4Z8I A;  3UML A;  2F2L X;  1YCK A;  1Z6I A;  2WKX A;  2XZ8 A;  1J3G A;  3D2Z A;  3TRU A;  2APH A;  3QS0 A;  5E0A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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