2Y50A

Crystal structure of collagenase g from clostridium histolyticum at 2. 80 angstrom resolution
Total Genus 242
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
242
sequence length
674
structure length
672
Chain Sequence
b'TMYDFEYLNGLSYTELTNLIKNIKWNQINGLFNYSTGSQKFFGDKNRVQAIINALQESGRTYTANDMKGIETFTEVLRAGFYLGYYNDGLSYLNDRNFQDKCIPAMIAIQKNPNFKLGTAVQDEVITSLGKLIGNASANAEVVNNCVPVLKQFRENLNQYAPDYVKGTAVNELIKGIEFDFSGAAYEKDVKTMPWYGKIDPFINELKALGLYGNITSATEWASDVGIYYLSKFGLYSTNRNDIVQSLEKAVDMYKYGKIAFVAMERITWDYDGIGSNGKKVDHDKFLDDAEKHYLPKTYTFDNGTFIIRAGDKVSEEKIKRLYWASREVKSQFHRVVGNDKALEVGNADDVLTMKIFNSPEEYKFNTNINGVSTDNGGLYIEPRGTFYTYERTPQQSIFSLEELFRHEYTHYLQARYLVDGLWGQGPFYEKNRLTWFDEGTAEFFAGSTRTSGVLPRKLILGYLAKDKVDHRYSLKKTLNSDDSDWMFYNYGFAVAHYLYEKDMPTFIKMNKAILNTDVKSYDEIIKKLSDDANKNTEYQNHIQELVDKYQGAGIPLVSDDYLKDHGYKKASEVYSEISKAASLTNTSVTAEKSQYFNTFTLRGTYTGETSKGEFKDWDEMSKKLDGTLESLAKNSWSGYKTLTAYFTNYRVTSDNKVQYDVVFHGVLTDNG'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords COLLAGENASE
publication title Structure of Collagenase G Reveals a Chew-and -Digest Mechanism of Bacterial Collagenolysis
pubmed doi rcsb
source organism Clostridium histolyticum
molecule tags Hydrolase
total genus 242
structure length 672
sequence length 674
ec nomenclature ec 3.4.24.3: Microbial collagenase.
pdb deposition date 2011-01-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00801 PKD PKD domain
A PF01752 Peptidase_M9 Collagenase
A PF08453 Peptidase_M9_N Peptidase family M9 N-terminal
A PF18496 ColG_sub Collagenase G catalytic helper subdomain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.980.50 Alpha Beta 2-Layer Sandwich Threonyl-tRNA Synthetase; Chain A, domain 2 Threonyl-tRNA Synthetase; Chain A, domain 2 2y50A02
4AREA 2Y3UA 4AR8A 4AR9A 2Y50A 4ARFA 4AR1A 2Y6IA
chains in the Genus database with same CATH superfamily
1TJEA 2ZTGA 1WZCA 2IUUA 4A0AA 1QF6A 3ZW7A 4AR8A 3I7HA 3ZTWA 3I7OA 3ZWKA 3E0CA 3ZUPA 1NYRA 4CI3A 4A08A 4A09A 3EI2A 3ZTYA 3I8EA 2ZZFA 2B5MA 3I7LA 3ZU6A 3ZX5A 1TKGA 4A11A 4CI2A 3I7PA 4A0BA 1TKEA 4E5ZA 1WXOA 2HYEA 3EI1A 2ZOSA 3ZX4A 1TKYA 2IUTA 2Y6IA 3RHUA 3I89A 4TZ4A 1XVIA 3EI3A 3ZWDA 3RFNA 3WQZA 1V7OA 2Y50A 3EI4A 3I8CA 4ARFA 2IUSA 3KEWA 5FQDA 4CI1A 1WNUA 4AREA 1NYQA 3I7KA 2Y3UA 4E54A 2ZZGA 2ZZEA 4AR9A 3I7NA 4AR1A 1V4PA 2E1BA 2B5LA
chains in the Genus database with same CATH topology
1TJEA 2ZTGA 4A0AA 2IUUA 1QF6A 4AR8A 3I7HA 3I7OA 3E0CA 1NYRA 4CI3A 4A08A 4A09A 3EI2A 3I8EA 2ZZFA 2B5MA 3I7LA 4CI2A 1TKGA 4A11A 3I7PA 4A0BA 1TKEA 4E5ZA 1WXOA 2HYEA 3EI1A 1TKYA 2IUTA 2Y6IA 3RHUA 3I89A 4TZ4A 3EI3A 3WQZA 3RFNA 1V7OA 2Y50A 3EI4A 3I8CA 4ARFA 2IUSA 3KEWA 5FQDA 4CI1A 1WNUA 4AREA 1NYQA 3I7KA 2Y3UA 4E54A 2ZZGA 2ZZEA 4AR9A 3I7NA 4AR1A 1V4PA 2E1BA 2B5LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ARE A;  2Y3U A;  4AR8 A;  4AR9 A;  2Y50 A;  4ARF A;  4AR1 A;  2Y6I A; 
#chains in the Genus database with same CATH topology
 1TJE A;  2ZTG A;  1WZC A;  2IUU A;  4A0A A;  1QF6 A;  3ZW7 A;  4AR8 A;  3I7H A;  3ZTW A;  3I7O A;  3ZWK A;  3E0C A;  3ZUP A;  1NYR A;  4CI3 A;  4A08 A;  4A09 A;  3EI2 A;  3ZTY A;  3I8E A;  2ZZF A;  2B5M A;  3I7L A;  3ZU6 A;  3ZX5 A;  1TKG A;  4A11 A;  4CI2 A;  3I7P A;  4A0B A;  1TKE A;  4E5Z A;  1WXO A;  2HYE A;  3EI1 A;  2ZOS A;  3ZX4 A;  1TKY A;  2IUT A;  2Y6I A;  3RHU A;  3I89 A;  4TZ4 A;  1XVI A;  3EI3 A;  3ZWD A;  3RFN A;  3WQZ A;  1V7O A;  2Y50 A;  3EI4 A;  3I8C A;  4ARF A;  2IUS A;  3KEW A;  5FQD A;  4CI1 A;  1WNU A;  4ARE A;  1NYQ A;  3I7K A;  2Y3U A;  4E54 A;  2ZZG A;  2ZZE A;  4AR9 A;  3I7N A;  4AR1 A;  1V4P A;  2E1B A;  2B5L A; 
#chains in the Genus database with same CATH homology
 1TJE A;  2ZTG A;  4A0A A;  2IUU A;  1QF6 A;  4AR8 A;  3I7H A;  3I7O A;  3E0C A;  1NYR A;  4CI3 A;  4A08 A;  4A09 A;  3EI2 A;  3I8E A;  2ZZF A;  2B5M A;  3I7L A;  4CI2 A;  1TKG A;  4A11 A;  3I7P A;  4A0B A;  1TKE A;  4E5Z A;  1WXO A;  2HYE A;  3EI1 A;  1TKY A;  2IUT A;  2Y6I A;  3RHU A;  3I89 A;  4TZ4 A;  3EI3 A;  3WQZ A;  3RFN A;  1V7O A;  2Y50 A;  3EI4 A;  3I8C A;  4ARF A;  2IUS A;  3KEW A;  5FQD A;  4CI1 A;  1WNU A;  4ARE A;  1NYQ A;  3I7K A;  2Y3U A;  4E54 A;  2ZZG A;  2ZZE A;  4AR9 A;  3I7N A;  4AR1 A;  1V4P A;  2E1B A;  2B5L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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