2Y6IA

Crystal structure of collagenase g from clostridium histolyticum in complex with isoamylphosphonyl-gly-pro-ala at 3.25 angstrom resolution
Total Genus 237
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
237
sequence length
674
structure length
671
Chain Sequence
TMYDFEYLNGLSYTELTNLIKNIKWNQINGLFNYSTGSQKFFGDKNRVQAIINALQESGRTYTANDMKGIETFTEVLRAGFYLGYYNDGLSYLNDRNFQDKCIPAMIAIQKNPNFKLGTAVQDEVITSLGKLIGNASANAEVVNNCVPVLKQFRENLNQYAPDYVKGTAVNELIKGIEFDFSGAAYEKDVKTMPWYGKIDPFINELKALGLYGNITSATEWASDVGIYYLSKFGLYSTNRNDIVQSLEKAVDMYKYGKIAFVAMERITWDYDGIGSNGKKVDHDKFLDDAEKHYLPKTYTFDNGTFIIRAGDKVSEEKIKRLYWASREVKSQFHRVVGNDKALEVGNADDVLTMKIFNSPEEYKFNTNINGVSTDNGGLYIEPRGTFYTYERTPQQSIFSLEELFRHEYTHYLQARYLVDGLWGQGPFYEKNRLTWFDEGTAEFFAGSTRTSGVLPRKLILGYLAKDKVDHRYSLKKTLNSDSDWMFYNYGFAVAHYLYEKDMPTFIKMNKAILNTDVKSYDEIIKKLSDDANKNTEYQNHIQELVDKYQGAGIPLVSDDYLKDHGYKKASEVYSEISKAASLTNTSVTAEKSQYFNTFTLRGTYTGETSKGEFKDWDEMSKKLDGTLESLAKNSWSGYKTLTAYFTNYRVTSDNKVQYDVVFHGVLTDNG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of Collagenase G Reveals a Chew-and -Digest Mechanism of Bacterial Collagenolysis
pubmed doi rcsb
source organism Clostridium histolyticum
molecule tags Hydrolase/inhibitor
molecule keywords COLLAGENASE
total genus 237
structure length 671
sequence length 674
ec nomenclature ec 3.4.24.3: Microbial collagenase.
pdb deposition date 2011-01-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00801 PKD PKD domain
A PF01752 Peptidase_M9 Collagenase
A PF08453 Peptidase_M9_N Peptidase family M9 N-terminal
A PF18496 ColG_sub Collagenase G catalytic helper subdomain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.980.50 Alpha Beta 2-Layer Sandwich Threonyl-tRNA Synthetase; Chain A, domain 2 Threonyl-tRNA Synthetase; Chain A, domain 2 2y6iA02
2Y6IA 4ARFA 4AR9A 4AR1A 4AR8A 4AREA 2Y3UA 2Y50A
chains in the Genus database with same CATH superfamily
3WQZA 1TKEA 2ZZFA 3I7KA 3RFNA 4CI1A 2HYEA 2ZZGA 1WZCA 2B5LA 2IUTA 4AR9A 3I7NA 3I8EA 4A09A 3ZWDA 4E54A 1XVIA 3I7OA 4A11A 4CI3A 3I7LA 3ZX5A 4A0AA 2ZZEA 3ZU6A 3I8CA 1TJEA 4CI2A 3I89A 2IUUA 3RHUA 3ZTYA 1NYQA 4AR8A 2ZTGA 4AREA 4AR1A 4E5ZA 1QF6A 4TZ4A 3ZW7A 3E0CA 5FQDA 3KEWA 4A0BA 3EI4A 2IUSA 2Y6IA 2E1BA 3ZX4A 3EI3A 3ZUPA 1V4PA 1WNUA 1WXOA 3ZWKA 3EI2A 2B5MA 3I7PA 4A08A 3ZTWA 3EI1A 1TKGA 4ARFA 1NYRA 1V7OA 2Y3UA 3I7HA 2Y50A 1TKYA 2ZOSA
chains in the Genus database with same CATH topology
3WQZA 1TKEA 2ZZFA 3I7KA 3RFNA 4CI1A 2HYEA 2ZZGA 2B5LA 2IUTA 4AR9A 3I7NA 3I8EA 4A09A 4E54A 3I7OA 4A11A 4CI3A 3I7LA 4A0AA 2ZZEA 3I8CA 1TJEA 4CI2A 3I89A 2IUUA 3RHUA 4AR8A 1NYQA 4AREA 2ZTGA 4E5ZA 4AR1A 1QF6A 4TZ4A 3E0CA 5FQDA 3KEWA 4A0BA 3EI4A 2IUSA 2Y6IA 2E1BA 3EI3A 1V4PA 1WNUA 3EI2A 2B5MA 3I7PA 4A08A 3EI1A 1TKGA 4ARFA 1NYRA 1V7OA 2Y3UA 3I7HA 2Y50A 1TKYA 1WXOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Y6I A;  4ARF A;  4AR9 A;  4AR1 A;  4AR8 A;  4ARE A;  2Y3U A;  2Y50 A; 
#chains in the Genus database with same CATH topology
 3WQZ A;  1TKE A;  2ZZF A;  3I7K A;  3RFN A;  4CI1 A;  2HYE A;  2ZZG A;  1WZC A;  2B5L A;  2IUT A;  4AR9 A;  3I7N A;  3I8E A;  4A09 A;  3ZWD A;  4E54 A;  1XVI A;  3I7O A;  4A11 A;  4CI3 A;  3I7L A;  3ZX5 A;  4A0A A;  2ZZE A;  3ZU6 A;  3I8C A;  1TJE A;  4CI2 A;  3I89 A;  2IUU A;  3RHU A;  3ZTY A;  1NYQ A;  4AR8 A;  2ZTG A;  4ARE A;  4AR1 A;  4E5Z A;  1QF6 A;  4TZ4 A;  3ZW7 A;  3E0C A;  5FQD A;  3KEW A;  4A0B A;  3EI4 A;  2IUS A;  2Y6I A;  2E1B A;  3ZX4 A;  3EI3 A;  3ZUP A;  1V4P A;  1WNU A;  1WXO A;  3ZWK A;  3EI2 A;  2B5M A;  3I7P A;  4A08 A;  3ZTW A;  3EI1 A;  1TKG A;  4ARF A;  1NYR A;  1V7O A;  2Y3U A;  3I7H A;  2Y50 A;  1TKY A;  2ZOS A; 
#chains in the Genus database with same CATH homology
 3WQZ A;  1TKE A;  2ZZF A;  3I7K A;  3RFN A;  4CI1 A;  2HYE A;  2ZZG A;  2B5L A;  2IUT A;  4AR9 A;  3I7N A;  3I8E A;  4A09 A;  4E54 A;  3I7O A;  4A11 A;  4CI3 A;  3I7L A;  4A0A A;  2ZZE A;  3I8C A;  1TJE A;  4CI2 A;  3I89 A;  2IUU A;  3RHU A;  4AR8 A;  1NYQ A;  4ARE A;  2ZTG A;  4E5Z A;  4AR1 A;  1QF6 A;  4TZ4 A;  3E0C A;  5FQD A;  3KEW A;  4A0B A;  3EI4 A;  2IUS A;  2Y6I A;  2E1B A;  3EI3 A;  1V4P A;  1WNU A;  3EI2 A;  2B5M A;  3I7P A;  4A08 A;  3EI1 A;  1TKG A;  4ARF A;  1NYR A;  1V7O A;  2Y3U A;  3I7H A;  2Y50 A;  1TKY A;  1WXO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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