4AREA

Crystal structure of the collagenase unit of collagenase g from clostridium histolyticum at 2.19 angstrom resolution.
Total Genus 258
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
258
sequence length
680
structure length
678
Chain Sequence
b'NLYFQTMYDFEYLNGLSYTELTNLIKNIKWNQINGLFNYSTGSQKFFGDKNRVQAIINALQESGRTYTANDMKGIETFTEVLRAGFYLGYYNDGLSYLNDRNFQDKCIPAMIAIQKNPNFKLGTAVQDEVITSLGKLIGNASANAEVVNNCVPVLKQFRENLNQYAPDYVKGTAVNELIKGIEFDFSGAAYEKDVKTMPWYGKIDPFINELKALGLYGNITSATEWASDVGIYYLSKFGLYSTNRNDIVQSLEKAVDMYKYGKIAFVAMERITWDYDGIGSNGKKVDHDKFLDDAEKHYLPKTYTFDNGTFIIRAGDKVSEEKIKRLYWASREVKSQFHRVVGNDKALEVGNADDVLTMKIFNSPEEYKFNTNINGVSTDNGGLYIEPRGTFYTYERTPQQSIFSLEELFRHEYTHYLQARYLVDGLWGQGPFYEKNRLTWFDEGTAEFFAGSTRTSGVLPRKLILGYLAKDKVDHRYSLKKTLNSGYDDSDWMFYNYGFAVAHYLYEKDMPTFIKMNKAILNTDVKSYDEIIKKLSDDANKNTEYQNHIQELVDKYQGAGIPLVSDDYLKDHGYKKASEVYSEISKAASLTNTSVTAEKSQYFNTFTLRGTYTGETSKGEFKDWDEMSKKLDGTLESLAKNSWSGYKTLTAYFTNYRVTSDNKVQYDVVFHGVLTDN'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords COLLAGENASE G
publication title Structural Basis for Activity Regulation and Substrate Preference of Clostridial Collagenases G, H, and T.
pubmed doi rcsb
source organism Clostridium histolyticum
molecule tags Hydrolase
total genus 258
structure length 678
sequence length 680
ec nomenclature ec 3.4.24.3: Microbial collagenase.
pdb deposition date 2012-04-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01752 Peptidase_M9 Collagenase
A PF08453 Peptidase_M9_N Peptidase family M9 N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.980.50 Alpha Beta 2-Layer Sandwich Threonyl-tRNA Synthetase; Chain A, domain 2 Threonyl-tRNA Synthetase; Chain A, domain 2 4areA02
4ARFA 4AR9A 2Y3UA 4AR8A 2Y50A 4AR1A 4AREA 2Y6IA
chains in the Genus database with same CATH superfamily
4E54A 1TKYA 5FQDA 2IUTA 2E1BA 3E0CA 2Y50A 3ZWKA 4AR8A 4A09A 2ZOSA 3WQZA 1WNUA 3I7KA 3KEWA 3I89A 3I7OA 2ZTGA 3ZUPA 3ZX4A 1TJEA 1QF6A 2ZZFA 4CI3A 2IUSA 1XVIA 1TKEA 3I7LA 4AR1A 3EI2A 1V7OA 3RFNA 2B5MA 4ARFA 4E5ZA 1NYQA 2ZZGA 4A0AA 4AR9A 2Y3UA 1WXOA 1V4PA 3ZTWA 3ZX5A 3I8CA 2HYEA 3EI4A 2ZZEA 2Y6IA 2IUUA 4CI2A 3EI1A 3ZW7A 3EI3A 3ZWDA 3I7PA 4A0BA 3ZTYA 4CI1A 4TZ4A 4A08A 1TKGA 1WZCA 3I7HA 3ZU6A 1NYRA 3I7NA 3I8EA 4A11A 3RHUA 4AREA 2B5LA
chains in the Genus database with same CATH topology
4E54A 1TKYA 5FQDA 2IUTA 2E1BA 3E0CA 2Y50A 4AR8A 4A09A 3WQZA 1WNUA 3I7KA 3KEWA 3I89A 3I7OA 2ZTGA 1QF6A 1TJEA 2ZZFA 4CI3A 2IUSA 1TKEA 3I7LA 4AR1A 3EI2A 1V7OA 3RFNA 2B5MA 4ARFA 4E5ZA 1NYQA 2ZZGA 4A0AA 4AR9A 2Y3UA 1WXOA 1V4PA 3I8CA 2HYEA 3EI4A 2ZZEA 2Y6IA 2IUUA 4CI2A 3EI1A 4A0BA 3EI3A 4A08A 3I7PA 4CI1A 4TZ4A 1TKGA 3I7HA 1NYRA 3I7NA 3I8EA 4A11A 3RHUA 4AREA 2B5LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ARF A;  4AR9 A;  2Y3U A;  4AR8 A;  2Y50 A;  4AR1 A;  4ARE A;  2Y6I A; 
#chains in the Genus database with same CATH topology
 4E54 A;  1TKY A;  5FQD A;  2IUT A;  2E1B A;  3E0C A;  2Y50 A;  3ZWK A;  4AR8 A;  4A09 A;  2ZOS A;  3WQZ A;  1WNU A;  3I7K A;  3KEW A;  3I89 A;  3I7O A;  2ZTG A;  3ZUP A;  3ZX4 A;  1TJE A;  1QF6 A;  2ZZF A;  4CI3 A;  2IUS A;  1XVI A;  1TKE A;  3I7L A;  4AR1 A;  3EI2 A;  1V7O A;  3RFN A;  2B5M A;  4ARF A;  4E5Z A;  1NYQ A;  2ZZG A;  4A0A A;  4AR9 A;  2Y3U A;  1WXO A;  1V4P A;  3ZTW A;  3ZX5 A;  3I8C A;  2HYE A;  3EI4 A;  2ZZE A;  2Y6I A;  2IUU A;  4CI2 A;  3EI1 A;  3ZW7 A;  3EI3 A;  3ZWD A;  3I7P A;  4A0B A;  3ZTY A;  4CI1 A;  4TZ4 A;  4A08 A;  1TKG A;  1WZC A;  3I7H A;  3ZU6 A;  1NYR A;  3I7N A;  3I8E A;  4A11 A;  3RHU A;  4ARE A;  2B5L A; 
#chains in the Genus database with same CATH homology
 4E54 A;  1TKY A;  5FQD A;  2IUT A;  2E1B A;  3E0C A;  2Y50 A;  4AR8 A;  4A09 A;  3WQZ A;  1WNU A;  3I7K A;  3KEW A;  3I89 A;  3I7O A;  2ZTG A;  1QF6 A;  1TJE A;  2ZZF A;  4CI3 A;  2IUS A;  1TKE A;  3I7L A;  4AR1 A;  3EI2 A;  1V7O A;  3RFN A;  2B5M A;  4ARF A;  4E5Z A;  1NYQ A;  2ZZG A;  4A0A A;  4AR9 A;  2Y3U A;  1WXO A;  1V4P A;  3I8C A;  2HYE A;  3EI4 A;  2ZZE A;  2Y6I A;  2IUU A;  4CI2 A;  3EI1 A;  4A0B A;  3EI3 A;  4A08 A;  3I7P A;  4CI1 A;  4TZ4 A;  1TKG A;  3I7H A;  1NYR A;  3I7N A;  3I8E A;  4A11 A;  3RHU A;  4ARE A;  2B5L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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