4AREA

Crystal structure of the collagenase unit of collagenase g from clostridium histolyticum at 2.19 angstrom resolution.
Total Genus 258
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
258
sequence length
680
structure length
678
Chain Sequence
NLYFQTMYDFEYLNGLSYTELTNLIKNIKWNQINGLFNYSTGSQKFFGDKNRVQAIINALQESGRTYTANDMKGIETFTEVLRAGFYLGYYNDGLSYLNDRNFQDKCIPAMIAIQKNPNFKLGTAVQDEVITSLGKLIGNASANAEVVNNCVPVLKQFRENLNQYAPDYVKGTAVNELIKGIEFDFSGAAYEKDVKTMPWYGKIDPFINELKALGLYGNITSATEWASDVGIYYLSKFGLYSTNRNDIVQSLEKAVDMYKYGKIAFVAMERITWDYDGIGSNGKKVDHDKFLDDAEKHYLPKTYTFDNGTFIIRAGDKVSEEKIKRLYWASREVKSQFHRVVGNDKALEVGNADDVLTMKIFNSPEEYKFNTNINGVSTDNGGLYIEPRGTFYTYERTPQQSIFSLEELFRHEYTHYLQARYLVDGLWGQGPFYEKNRLTWFDEGTAEFFAGSTRTSGVLPRKLILGYLAKDKVDHRYSLKKTLNSGYDDSDWMFYNYGFAVAHYLYEKDMPTFIKMNKAILNTDVKSYDEIIKKLSDDANKNTEYQNHIQELVDKYQGAGIPLVSDDYLKDHGYKKASEVYSEISKAASLTNTSVTAEKSQYFNTFTLRGTYTGETSKGEFKDWDEMSKKLDGTLESLAKNSWSGYKTLTAYFTNYRVTSDNKVQYDVVFHGVLTDN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for Activity Regulation and Substrate Preference of Clostridial Collagenases G, H, and T.
pubmed doi rcsb
source organism Clostridium histolyticum
molecule tags Hydrolase
molecule keywords COLLAGENASE G
total genus 258
structure length 678
sequence length 680
ec nomenclature ec 3.4.24.3: Microbial collagenase.
pdb deposition date 2012-04-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01752 Peptidase_M9 Collagenase
A PF08453 Peptidase_M9_N Peptidase family M9 N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.980.50 Alpha Beta 2-Layer Sandwich Threonyl-tRNA Synthetase; Chain A, domain 2 Threonyl-tRNA Synthetase; Chain A, domain 2 4areA02
2Y50A 4AREA 4AR1A 2Y6IA 4AR9A 4ARFA 2Y3UA 4AR8A
chains in the Genus database with same CATH superfamily
1QF6A 1NYRA 2ZOSA 2IUUA 4AREA 3WQZA 3KEWA 2ZZFA 1NYQA 4AR1A 3I8CA 1TKEA 3ZW7A 1V4PA 2Y3UA 3ZX4A 4AR8A 2B5MA 2ZTGA 2E1BA 2Y50A 3ZX5A 5FQDA 1WNUA 4A11A 1XVIA 3ZUPA 3EI1A 4A08A 3ZWDA 4CI1A 2ZZEA 3I7LA 3I7PA 4AR9A 3I7HA 1TKYA 4ARFA 4CI3A 1TJEA 3EI4A 3ZU6A 3I7OA 2B5LA 4TZ4A 2ZZGA 4A09A 3I7KA 4A0BA 3ZTWA 2IUTA 3I89A 2IUSA 1V7OA 1WXOA 4E5ZA 1WZCA 3EI3A 3ZWKA 3E0CA 3EI2A 3I8EA 3I7NA 3RHUA 4A0AA 2HYEA 3RFNA 3ZTYA 2Y6IA 4E54A 4CI2A 1TKGA
chains in the Genus database with same CATH topology
1QF6A 1NYRA 2IUUA 4AREA 3WQZA 3KEWA 2ZZFA 1NYQA 4AR1A 3I8CA 1TKEA 1V4PA 2Y3UA 4AR8A 2B5MA 2ZTGA 2E1BA 2Y50A 5FQDA 1WNUA 4A11A 3EI1A 4A08A 4CI1A 2ZZEA 3I7LA 3I7PA 4AR9A 3I7HA 1TKYA 4ARFA 4CI3A 1TJEA 3EI4A 3I7OA 2B5LA 4TZ4A 2ZZGA 4A09A 3I7KA 4A0BA 2IUTA 3I89A 2IUSA 1V7OA 1WXOA 4E5ZA 3EI3A 3E0CA 3EI2A 3I8EA 3I7NA 3RHUA 4A0AA 2HYEA 3RFNA 2Y6IA 4E54A 4CI2A 1TKGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Y50 A;  4ARE A;  4AR1 A;  2Y6I A;  4AR9 A;  4ARF A;  2Y3U A;  4AR8 A; 
#chains in the Genus database with same CATH topology
 1QF6 A;  1NYR A;  2ZOS A;  2IUU A;  4ARE A;  3WQZ A;  3KEW A;  2ZZF A;  1NYQ A;  4AR1 A;  3I8C A;  1TKE A;  3ZW7 A;  1V4P A;  2Y3U A;  3ZX4 A;  4AR8 A;  2B5M A;  2ZTG A;  2E1B A;  2Y50 A;  3ZX5 A;  5FQD A;  1WNU A;  4A11 A;  1XVI A;  3ZUP A;  3EI1 A;  4A08 A;  3ZWD A;  4CI1 A;  2ZZE A;  3I7L A;  3I7P A;  4AR9 A;  3I7H A;  1TKY A;  4ARF A;  4CI3 A;  1TJE A;  3EI4 A;  3ZU6 A;  3I7O A;  2B5L A;  4TZ4 A;  2ZZG A;  4A09 A;  3I7K A;  4A0B A;  3ZTW A;  2IUT A;  3I89 A;  2IUS A;  1V7O A;  1WXO A;  4E5Z A;  1WZC A;  3EI3 A;  3ZWK A;  3E0C A;  3EI2 A;  3I8E A;  3I7N A;  3RHU A;  4A0A A;  2HYE A;  3RFN A;  3ZTY A;  2Y6I A;  4E54 A;  4CI2 A;  1TKG A; 
#chains in the Genus database with same CATH homology
 1QF6 A;  1NYR A;  2IUU A;  4ARE A;  3WQZ A;  3KEW A;  2ZZF A;  1NYQ A;  4AR1 A;  3I8C A;  1TKE A;  1V4P A;  2Y3U A;  4AR8 A;  2B5M A;  2ZTG A;  2E1B A;  2Y50 A;  5FQD A;  1WNU A;  4A11 A;  3EI1 A;  4A08 A;  4CI1 A;  2ZZE A;  3I7L A;  3I7P A;  4AR9 A;  3I7H A;  1TKY A;  4ARF A;  4CI3 A;  1TJE A;  3EI4 A;  3I7O A;  2B5L A;  4TZ4 A;  2ZZG A;  4A09 A;  3I7K A;  4A0B A;  2IUT A;  3I89 A;  2IUS A;  1V7O A;  1WXO A;  4E5Z A;  3EI3 A;  3E0C A;  3EI2 A;  3I8E A;  3I7N A;  3RHU A;  4A0A A;  2HYE A;  3RFN A;  2Y6I A;  4E54 A;  4CI2 A;  1TKG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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