2QEXR

Negamycin binds to the wall of the nascent chain exit tunnel of the 50s ribosomal subunit
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Negamycin binds to the wall of the nascent chain exit tunnel of the 50S ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 38
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2007-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 2qexR00
3I56R 5JVHP 3CD6R 1VQ6R 3CCMR 4V19W 4U67P 3CCRR 3J7ZS 4IO9P 1Q7YS 1VQLR 3G71R 2QA4R 3G4SR 1VQMR 1K8AS 1QVGQ 4UY8S 1Q82S 5DM6P 4WFBP 4WCEP 1VQ8R 2OTLR 1VQOR 1YI2R 1KC8S 1BXEA 4IOAP 3CCVR 1VQ5R 1N8RS 3CCER 5GAGT 1YJWR 5HL7P 1Q86S 3J7YT 1VQ4R 1M90S 1K9MS 2ZJQP 4IOCP 4WF9P 1VQ7R 3OW2Q 1S72R 1YJ9R 3PIOP 3CC2R 1I4JA 3PIPP 1NJIS 1VQKR 3CC4R 1VQPR 3CMAR 2OTJR 3CCSR 3G6ER 1VQNR 1KD1S 5GAHT 3DLLP 1VQ9R 2ZJRP 1M1KS 3CPWQ 3CMER 3CF5P 5JVGP 1Q81S 3CC7R 1YIJR 1KQSQ 3CCLR 3CCQR 2QEXR 3CCJR 1YHQR 1JJ2Q 1QVFQ 2ZJPP 5MLCU 5H1SU 4WFAP 1K73S 3CXCQ 5GAET 3I55R 5DM7P 1W2BQ 1YJNR 1YITR 3CCUR 4WFNP 5GADT
chains in the Genus database with same CATH superfamily
2BYDA 3I56R 5JVHP 2D0PA 3CD6R 1FTFA 1FTEA 1VQ6R 3CCMR 4V19W 4U67P 2WDOA 3CCRR 3J7ZS 4IO9P 1Q7YS 1VQLR 3G71R 1QR0A 2QA4R 3G4SR 1VQMR 1K8AS 1QVGQ 2WDYA 4UY8S 1Q82S 5DM6P 4WFBP 3H7QA 4WCEP 1VQ8R 2QG8A 2BDDA 1F7LA 3NE1A 4JM7A 2OTLR 1VQOR 2CG5A 1YI2R 2JBZA 1KC8S 1BXEA 4IOAP 3CCVR 3NFDA 1VQ5R 1N8RS 3CCER 5GAGT 1NBWA 1YJWR 5HL7P 2C43A 1FTHA 4DXEA 1Q86S 3J7YT 1VQ4R 1M90S 1K9MS 2ZJQP 4IOCP 4WF9P 1VQ7R 3OW2Q 1S72R 1YJ9R 3PIOP 3CC2R 1I4JA 3PIPP 1NJIS 4HC6A 1VQKR 3CC4R 3QMNA 1VQPR 3CMAR 2OTJR 3NE3B 3CCSR 3G6ER 1VQNR 1KD1S 2JCAA 5GAHT 3DLLP 3NE9A 1VQ9R 3HQJA 5CMOA 2ZJRP 1M1KS 3CPWQ 3CMER 3CF5P 5JVGP 1Q81S 3HYKA 1F80A 3CC7R 5CXDA 1YIJR 1F7TA 2D0OA 1KQSQ 2WASA 3CCLR 3CCQR 2QEXR 4MRTA 3CCJR 1YHQR 1JJ2Q 1QVFQ 2ZJPP 5MLCU 5H1SU 4WFAP 1K73S 4WFNP 3CXCQ 5GAET 3I55R 5DM7P 2WATA 1W2BQ 1YJNR 2WDSA 3GWMA 1YITR 3CCUR 2WASB 5GADT
chains in the Genus database with same CATH topology
3I56R 5JVHP 3CD6R 1VQ6R 3CCMR 4V19W 4U67P 3CCRR 3J7ZS 4IO9P 1Q7YS 1VQLR 3G71R 2QA4R 3G4SR 1VQMR 1K8AS 1QVGQ 4UY8S 1Q82S 5DM6P 4WFBP 4WCEP 1VQ8R 2OTLR 1VQOR 1YI2R 1KC8S 1BXEA 4IOAP 3CCVR 1VQ5R 1N8RS 3CCER 5GAGT 1YJWR 5HL7P 1Q86S 3J7YT 1VQ4R 1M90S 1K9MS 2ZJQP 4IOCP 4WF9P 1VQ7R 3OW2Q 1S72R 1YJ9R 3PIOP 3CC2R 1I4JA 3PIPP 1NJIS 1VQKR 3CC4R 1VQPR 3CMAR 2OTJR 3CCSR 3G6ER 1VQNR 1KD1S 5GAHT 3DLLP 1VQ9R 2ZJRP 1M1KS 3CPWQ 3CMER 3CF5P 5JVGP 1Q81S 3CC7R 1YIJR 1KQSQ 3CCLR 3CCQR 2QEXR 3CCJR 1YHQR 1JJ2Q 1QVFQ 2ZJPP 5MLCU 5H1SU 4WFAP 1K73S 3CXCQ 5GAET 3I55R 5DM7P 1W2BQ 1YJNR 1YITR 3CCUR 4WFNP 5GADT
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I56 R;  5JVH P;  3CD6 R;  1VQ6 R;  3CCM R;  4V19 W;  4U67 P;  3CCR R;  3J7Z S;  4IO9 P;  1Q7Y S;  1VQL R;  3G71 R;  2QA4 R;  3G4S R;  1VQM R;  1K8A S;  1QVG Q;  4UY8 S;  1Q82 S;  5DM6 P;  4WFB P;  4WCE P;  1VQ8 R;  2OTL R;  1VQO R;  1YI2 R;  1KC8 S;  1BXE A;  4IOA P;  3CCV R;  1VQ5 R;  1N8R S;  3CCE R;  5GAG T;  1YJW R;  5HL7 P;  1Q86 S;  3J7Y T;  1VQ4 R;  1M90 S;  1K9M S;  2ZJQ P;  4IOC P;  4WF9 P;  1VQ7 R;  3OW2 Q;  1S72 R;  1YJ9 R;  3PIO P;  3CC2 R;  1I4J A;  3PIP P;  1NJI S;  1VQK R;  3CC4 R;  1VQP R;  3CMA R;  2OTJ R;  3CCS R;  3G6E R;  1VQN R;  1KD1 S;  5GAH T;  3DLL P;  1VQ9 R;  2ZJR P;  1M1K S;  3CPW Q;  3CME R;  3CF5 P;  5JVG P;  1Q81 S;  3CC7 R;  1YIJ R;  1KQS Q;  3CCL R;  3CCQ R;  2QEX R;  3CCJ R;  1YHQ R;  1JJ2 Q;  1QVF Q;  2ZJP P;  5MLC U;  5H1S U;  4WFA P;  1K73 S;  3CXC Q;  5GAE T;  3I55 R;  5DM7 P;  1W2B Q;  1YJN R;  1YIT R;  3CCU R;  4WFN P;  5GAD T; 
#chains in the Genus database with same CATH topology
 2BYD A;  3I56 R;  5JVH P;  2D0P A;  3CD6 R;  1FTF A;  1FTE A;  1VQ6 R;  3CCM R;  4V19 W;  4U67 P;  2WDO A;  3CCR R;  3J7Z S;  4IO9 P;  1Q7Y S;  1VQL R;  3G71 R;  1QR0 A;  2QA4 R;  3G4S R;  1VQM R;  1K8A S;  1QVG Q;  2WDY A;  4UY8 S;  1Q82 S;  5DM6 P;  4WFB P;  3H7Q A;  4WCE P;  1VQ8 R;  2QG8 A;  2BDD A;  1F7L A;  3NE1 A;  4JM7 A;  2OTL R;  1VQO R;  2CG5 A;  1YI2 R;  2JBZ A;  1KC8 S;  1BXE A;  4IOA P;  3CCV R;  3NFD A;  1VQ5 R;  1N8R S;  3CCE R;  5GAG T;  1NBW A;  1YJW R;  5HL7 P;  2C43 A;  1FTH A;  4DXE A;  1Q86 S;  3J7Y T;  1VQ4 R;  1M90 S;  1K9M S;  2ZJQ P;  4IOC P;  4WF9 P;  1VQ7 R;  3OW2 Q;  1S72 R;  1YJ9 R;  3PIO P;  3CC2 R;  1I4J A;  3PIP P;  1NJI S;  4HC6 A;  1VQK R;  3CC4 R;  3QMN A;  1VQP R;  3CMA R;  2OTJ R;  3NE3 B;  3CCS R;  3G6E R;  1VQN R;  1KD1 S;  2JCA A;  5GAH T;  3DLL P;  3NE9 A;  1VQ9 R;  3HQJ A;  5CMO A;  2ZJR P;  1M1K S;  3CPW Q;  3CME R;  3CF5 P;  5JVG P;  1Q81 S;  3HYK A;  1F80 A;  3CC7 R;  5CXD A;  1YIJ R;  1F7T A;  2D0O A;  1KQS Q;  2WAS A;  3CCL R;  3CCQ R;  2QEX R;  4MRT A;  3CCJ R;  1YHQ R;  1JJ2 Q;  1QVF Q;  2ZJP P;  5MLC U;  5H1S U;  4WFA P;  1K73 S;  4WFN P;  3CXC Q;  5GAE T;  3I55 R;  5DM7 P;  2WAT A;  1W2B Q;  1YJN R;  2WDS A;  3GWM A;  1YIT R;  3CCU R;  2WAS B;  5GAD T; 
#chains in the Genus database with same CATH homology
 3I56 R;  5JVH P;  3CD6 R;  1VQ6 R;  3CCM R;  4V19 W;  4U67 P;  3CCR R;  3J7Z S;  4IO9 P;  1Q7Y S;  1VQL R;  3G71 R;  2QA4 R;  3G4S R;  1VQM R;  1K8A S;  1QVG Q;  4UY8 S;  1Q82 S;  5DM6 P;  4WFB P;  4WCE P;  1VQ8 R;  2OTL R;  1VQO R;  1YI2 R;  1KC8 S;  1BXE A;  4IOA P;  3CCV R;  1VQ5 R;  1N8R S;  3CCE R;  5GAG T;  1YJW R;  5HL7 P;  1Q86 S;  3J7Y T;  1VQ4 R;  1M90 S;  1K9M S;  2ZJQ P;  4IOC P;  4WF9 P;  1VQ7 R;  3OW2 Q;  1S72 R;  1YJ9 R;  3PIO P;  3CC2 R;  1I4J A;  3PIP P;  1NJI S;  1VQK R;  3CC4 R;  1VQP R;  3CMA R;  2OTJ R;  3CCS R;  3G6E R;  1VQN R;  1KD1 S;  5GAH T;  3DLL P;  1VQ9 R;  2ZJR P;  1M1K S;  3CPW Q;  3CME R;  3CF5 P;  5JVG P;  1Q81 S;  3CC7 R;  1YIJ R;  1KQS Q;  3CCL R;  3CCQ R;  2QEX R;  3CCJ R;  1YHQ R;  1JJ2 Q;  1QVF Q;  2ZJP P;  5MLC U;  5H1S U;  4WFA P;  1K73 S;  3CXC Q;  5GAE T;  3I55 R;  5DM7 P;  1W2B Q;  1YJN R;  1YIT R;  3CCU R;  4WFN P;  5GAD T; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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