3CCER

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535a
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 40
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2008-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 3cceR00
3G6ER 3CCRR 1M90S 4WF9P 3PIPP 1VQ5R 3CC2R 3CXCQ 1Q86S 4WFBP 3CCQR 4IOCP 3CCSR 1VQ8R 3CCER 3CF5P 1KC8S 2QA4R 1VQ6R 3J7YT 1Q82S 1QVFQ 1I4JA 1YI2R 1VQLR 1YHQR 1VQ7R 4WCEP 3PIOP 1NJIS 3CCJR 5JVGP 1VQMR 4WFAP 3G4SR 1JJ2Q 1VQNR 3OW2Q 5GADT 2OTJR 1VQ4R 2OTLR 5JVHP 3J7ZS 4U67P 5HL7P 3CD6R 3G71R 1N8RS 1M1KS 4IOAP 1K9MS 3CCLR 2ZJQP 5H1SU 1K8AS 4V19W 3CPWQ 3CC4R 3CC7R 1YJ9R 1Q7YS 1YITR 2ZJPP 2QEXR 5GAET 1BXEA 1KD1S 3I55R 4UY8S 1QVGQ 1YIJR 4IO9P 3I56R 3CCVR 1YJNR 3CCMR 5DM6P 5MLCU 5GAHT 1VQ9R 4WFNP 1W2BQ 5GAGT 1VQOR 5DM7P 3DLLP 1VQKR 3CCUR 1YJWR 1VQPR 1KQSQ 1Q81S 1S72R 1K73S 2ZJRP 3CMAR 3CMER
chains in the Genus database with same CATH superfamily
3G6ER 2WDOA 3CCRR 1M90S 4WF9P 3PIPP 1VQ5R 3CC2R 3CXCQ 1Q86S 4WFBP 3CCQR 4IOCP 3CCSR 1VQ8R 3CCER 3CF5P 5CMOA 3HQJA 1KC8S 2QA4R 1VQ6R 3J7YT 1Q82S 2WASA 5CXDA 1QVFQ 1I4JA 2WDYA 2BYDA 2C43A 1YHQR 1YI2R 1VQLR 1NBWA 1VQ7R 4WCEP 3PIOP 1NJIS 3H7QA 3CCJR 5JVGP 2QG8A 2JBZA 1VQMR 4WFAP 3G4SR 1JJ2Q 1VQNR 3OW2Q 4MRTA 3HYKA 2JCAA 5GADT 2OTJR 2D0PA 2WATA 1VQ4R 2OTLR 5JVHP 5HL7P 4U67P 3J7ZS 3CD6R 3G71R 1N8RS 2WASB 4DXEA 1M1KS 4IOAP 1F7LA 1K9MS 3CCLR 1FTFA 2ZJQP 5H1SU 1K8AS 4V19W 3CPWQ 3CC4R 1FTEA 3CC7R 1YJ9R 1Q7YS 1YITR 2ZJPP 2QEXR 5GAET 1BXEA 1KD1S 3I55R 4UY8S 1F80A 4HC6A 1QVGQ 1YIJR 4IO9P 3I56R 3NE3B 3CCVR 1YJNR 3CCMR 5DM6P 1FTHA 4JM7A 5GAHT 5MLCU 1VQ9R 4WFNP 1W2BQ 5GAGT 3NE9A 2WDSA 1VQOR 5DM7P 1QR0A 3DLLP 1VQKR 3CCUR 1F7TA 1YJWR 1VQPR 2BDDA 1KQSQ 2CG5A 1Q81S 1S72R 2D0OA 1K73S 3GWMA 3QMNA 2ZJRP 3NFDA 3NE1A 3CMAR 3CMER
chains in the Genus database with same CATH topology
3G6ER 3CCRR 1M90S 4WF9P 3PIPP 1VQ5R 3CC2R 3CXCQ 1Q86S 4WFBP 3CCQR 4IOCP 3CCSR 1VQ8R 3CCER 3CF5P 1KC8S 2QA4R 1VQ6R 3J7YT 1Q82S 1QVFQ 1I4JA 1YI2R 1VQLR 1YHQR 1VQ7R 4WCEP 3PIOP 1NJIS 3CCJR 5JVGP 1VQMR 4WFAP 3G4SR 1JJ2Q 1VQNR 3OW2Q 5GADT 2OTJR 1VQ4R 2OTLR 5JVHP 3J7ZS 4U67P 5HL7P 3CD6R 3G71R 1N8RS 1M1KS 4IOAP 1K9MS 3CCLR 2ZJQP 5H1SU 1K8AS 4V19W 3CPWQ 3CC4R 3CC7R 1YJ9R 1Q7YS 1YITR 2ZJPP 2QEXR 5GAET 1BXEA 1KD1S 3I55R 4UY8S 1QVGQ 1YIJR 4IO9P 3I56R 3CCVR 1YJNR 3CCMR 5DM6P 5MLCU 5GAHT 1VQ9R 4WFNP 1W2BQ 5GAGT 1VQOR 5DM7P 3DLLP 1VQKR 3CCUR 1YJWR 1VQPR 1KQSQ 1Q81S 1S72R 1K73S 2ZJRP 3CMAR 3CMER
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G6E R;  3CCR R;  1M90 S;  4WF9 P;  3PIP P;  1VQ5 R;  3CC2 R;  3CXC Q;  1Q86 S;  4WFB P;  3CCQ R;  4IOC P;  3CCS R;  1VQ8 R;  3CCE R;  3CF5 P;  1KC8 S;  2QA4 R;  1VQ6 R;  3J7Y T;  1Q82 S;  1QVF Q;  1I4J A;  1YI2 R;  1VQL R;  1YHQ R;  1VQ7 R;  4WCE P;  3PIO P;  1NJI S;  3CCJ R;  5JVG P;  1VQM R;  4WFA P;  3G4S R;  1JJ2 Q;  1VQN R;  3OW2 Q;  5GAD T;  2OTJ R;  1VQ4 R;  2OTL R;  5JVH P;  3J7Z S;  4U67 P;  5HL7 P;  3CD6 R;  3G71 R;  1N8R S;  1M1K S;  4IOA P;  1K9M S;  3CCL R;  2ZJQ P;  5H1S U;  1K8A S;  4V19 W;  3CPW Q;  3CC4 R;  3CC7 R;  1YJ9 R;  1Q7Y S;  1YIT R;  2ZJP P;  2QEX R;  5GAE T;  1BXE A;  1KD1 S;  3I55 R;  4UY8 S;  1QVG Q;  1YIJ R;  4IO9 P;  3I56 R;  3CCV R;  1YJN R;  3CCM R;  5DM6 P;  5MLC U;  5GAH T;  1VQ9 R;  4WFN P;  1W2B Q;  5GAG T;  1VQO R;  5DM7 P;  3DLL P;  1VQK R;  3CCU R;  1YJW R;  1VQP R;  1KQS Q;  1Q81 S;  1S72 R;  1K73 S;  2ZJR P;  3CMA R;  3CME R; 
#chains in the Genus database with same CATH topology
 3G6E R;  2WDO A;  3CCR R;  1M90 S;  4WF9 P;  3PIP P;  1VQ5 R;  3CC2 R;  3CXC Q;  1Q86 S;  4WFB P;  3CCQ R;  4IOC P;  3CCS R;  1VQ8 R;  3CCE R;  3CF5 P;  5CMO A;  3HQJ A;  1KC8 S;  2QA4 R;  1VQ6 R;  3J7Y T;  1Q82 S;  2WAS A;  5CXD A;  1QVF Q;  1I4J A;  2WDY A;  2BYD A;  2C43 A;  1YHQ R;  1YI2 R;  1VQL R;  1NBW A;  1VQ7 R;  4WCE P;  3PIO P;  1NJI S;  3H7Q A;  3CCJ R;  5JVG P;  2QG8 A;  2JBZ A;  1VQM R;  4WFA P;  3G4S R;  1JJ2 Q;  1VQN R;  3OW2 Q;  4MRT A;  3HYK A;  2JCA A;  5GAD T;  2OTJ R;  2D0P A;  2WAT A;  1VQ4 R;  2OTL R;  5JVH P;  5HL7 P;  4U67 P;  3J7Z S;  3CD6 R;  3G71 R;  1N8R S;  2WAS B;  4DXE A;  1M1K S;  4IOA P;  1F7L A;  1K9M S;  3CCL R;  1FTF A;  2ZJQ P;  5H1S U;  1K8A S;  4V19 W;  3CPW Q;  3CC4 R;  1FTE A;  3CC7 R;  1YJ9 R;  1Q7Y S;  1YIT R;  2ZJP P;  2QEX R;  5GAE T;  1BXE A;  1KD1 S;  3I55 R;  4UY8 S;  1F80 A;  4HC6 A;  1QVG Q;  1YIJ R;  4IO9 P;  3I56 R;  3NE3 B;  3CCV R;  1YJN R;  3CCM R;  5DM6 P;  1FTH A;  4JM7 A;  5GAH T;  5MLC U;  1VQ9 R;  4WFN P;  1W2B Q;  5GAG T;  3NE9 A;  2WDS A;  1VQO R;  5DM7 P;  1QR0 A;  3DLL P;  1VQK R;  3CCU R;  1F7T A;  1YJW R;  1VQP R;  2BDD A;  1KQS Q;  2CG5 A;  1Q81 S;  1S72 R;  2D0O A;  1K73 S;  3GWM A;  3QMN A;  2ZJR P;  3NFD A;  3NE1 A;  3CMA R;  3CME R; 
#chains in the Genus database with same CATH homology
 3G6E R;  3CCR R;  1M90 S;  4WF9 P;  3PIP P;  1VQ5 R;  3CC2 R;  3CXC Q;  1Q86 S;  4WFB P;  3CCQ R;  4IOC P;  3CCS R;  1VQ8 R;  3CCE R;  3CF5 P;  1KC8 S;  2QA4 R;  1VQ6 R;  3J7Y T;  1Q82 S;  1QVF Q;  1I4J A;  1YI2 R;  1VQL R;  1YHQ R;  1VQ7 R;  4WCE P;  3PIO P;  1NJI S;  3CCJ R;  5JVG P;  1VQM R;  4WFA P;  3G4S R;  1JJ2 Q;  1VQN R;  3OW2 Q;  5GAD T;  2OTJ R;  1VQ4 R;  2OTL R;  5JVH P;  3J7Z S;  4U67 P;  5HL7 P;  3CD6 R;  3G71 R;  1N8R S;  1M1K S;  4IOA P;  1K9M S;  3CCL R;  2ZJQ P;  5H1S U;  1K8A S;  4V19 W;  3CPW Q;  3CC4 R;  3CC7 R;  1YJ9 R;  1Q7Y S;  1YIT R;  2ZJP P;  2QEX R;  5GAE T;  1BXE A;  1KD1 S;  3I55 R;  4UY8 S;  1QVG Q;  1YIJ R;  4IO9 P;  3I56 R;  3CCV R;  1YJN R;  3CCM R;  5DM6 P;  5MLC U;  5GAH T;  1VQ9 R;  4WFN P;  1W2B Q;  5GAG T;  1VQO R;  5DM7 P;  3DLL P;  1VQK R;  3CCU R;  1YJW R;  1VQP R;  1KQS Q;  1Q81 S;  1S72 R;  1K73 S;  2ZJR P;  3CMA R;  3CME R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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