3CCRR

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488c. density for anisomycin is visible but not included in the model.
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 37
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 3ccrR00
1YHQR 5GAHT 5GADT 1VQ8R 5JVHP 3DLLP 3CPWQ 5DM7P 2QA4R 4UY8S 1W2BQ 3I56R 3OW2Q 3G6ER 4IOAP 4IO9P 3CCSR 1K9MS 5GAGT 3CC4R 1VQLR 2OTLR 2ZJPP 1Q86S 1YITR 5HL7P 1VQ6R 1KD1S 1VQKR 3CCLR 1VQ4R 3J7YT 1YI2R 1Q7YS 3PIOP 1QVFQ 1M90S 3CCMR 1K8AS 2ZJQP 2QEXR 3CC7R 4WFAP 1VQPR 3CCQR 4V19W 5JVGP 1S72R 4WFBP 5GAET 1VQ7R 4WF9P 1JJ2Q 5H1SU 1VQMR 4WCEP 1KC8S 3CMER 1VQ5R 1Q81S 4U67P 5DM6P 3CCVR 3CD6R 3CF5P 3CMAR 1KQSQ 1YJ9R 1Q82S 1K73S 2ZJRP 2OTJR 1BXEA 1YIJR 3G71R 1VQOR 3CCRR 4IOCP 1NJIS 1YJNR 1YJWR 3CCER 3PIPP 1N8RS 1M1KS 1VQNR 1I4JA 1QVGQ 3CXCQ 3I55R 3G4SR 5MLCU 3CC2R 3J7ZS 4WFNP 1VQ9R 3CCUR 3CCJR
chains in the Genus database with same CATH superfamily
1YHQR 5GAHT 3H7QA 1FTEA 5GADT 1VQ8R 5JVHP 3DLLP 1NBWA 5DM7P 3CPWQ 2QA4R 4UY8S 1W2BQ 3I56R 2BYDA 3OW2Q 3G6ER 4IOAP 4IO9P 3NFDA 3CCSR 1K9MS 4HC6A 5GAGT 1F7LA 3CC4R 1VQLR 2OTLR 3NE1A 2JBZA 2ZJPP 1Q86S 1YITR 5HL7P 1VQ6R 1KD1S 1VQKR 2D0PA 3CCLR 3HQJA 1VQ4R 3J7YT 2WASB 1YI2R 2JCAA 1F7TA 1Q7YS 3PIOP 5CXDA 2CG5A 1M90S 1QVFQ 1FTFA 3CCMR 1K8AS 2ZJQP 2QEXR 3CC7R 4DXEA 4WFAP 1VQPR 3CCQR 4V19W 4MRTA 5JVGP 1S72R 2WDOA 4WFBP 3NE9A 5GAET 1VQ7R 4WF9P 1JJ2Q 2WDSA 5H1SU 2WASA 3NE3B 4JM7A 1VQMR 4WCEP 1KC8S 1F80A 2C43A 3CMER 1VQ5R 1Q81S 4U67P 5DM6P 3CCVR 3CD6R 3CF5P 2D0OA 3GWMA 3CMAR 1KQSQ 1YJ9R 1Q82S 1K73S 2ZJRP 2OTJR 2QG8A 3QMNA 1BXEA 1YIJR 3G71R 1VQOR 3CCRR 5CMOA 4IOCP 1FTHA 1NJIS 1YJNR 2WDYA 1QR0A 1YJWR 3CCER 3PIPP 1N8RS 3HYKA 1M1KS 1VQNR 1I4JA 1QVGQ 3CXCQ 3I55R 3G4SR 5MLCU 3CC2R 3J7ZS 4WFNP 2WATA 2BDDA 1VQ9R 3CCUR 3CCJR
chains in the Genus database with same CATH topology
1YHQR 5GAHT 5GADT 1VQ8R 5JVHP 3DLLP 3CPWQ 5DM7P 2QA4R 4UY8S 1W2BQ 3I56R 3OW2Q 3G6ER 4IOAP 4IO9P 3CCSR 1K9MS 5GAGT 3CC4R 1VQLR 2OTLR 2ZJPP 1Q86S 1YITR 5HL7P 1VQ6R 1KD1S 1VQKR 3CCLR 1VQ4R 3J7YT 1YI2R 1Q7YS 3PIOP 1QVFQ 1M90S 3CCMR 1K8AS 2ZJQP 2QEXR 3CC7R 4WFAP 1VQPR 3CCQR 4V19W 5JVGP 1S72R 4WFBP 5GAET 1VQ7R 4WF9P 1JJ2Q 5H1SU 1VQMR 4WCEP 1KC8S 3CMER 1VQ5R 1Q81S 4U67P 5DM6P 3CCVR 3CD6R 3CF5P 3CMAR 1KQSQ 1YJ9R 1Q82S 1K73S 2ZJRP 2OTJR 1BXEA 1YIJR 3G71R 1VQOR 3CCRR 4IOCP 1NJIS 1YJNR 1YJWR 3CCER 3PIPP 1N8RS 1M1KS 1VQNR 1I4JA 1QVGQ 3CXCQ 3I55R 3G4SR 5MLCU 3CC2R 3J7ZS 4WFNP 1VQ9R 3CCUR 3CCJR
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YHQ R;  5GAH T;  5GAD T;  1VQ8 R;  5JVH P;  3DLL P;  3CPW Q;  5DM7 P;  2QA4 R;  4UY8 S;  1W2B Q;  3I56 R;  3OW2 Q;  3G6E R;  4IOA P;  4IO9 P;  3CCS R;  1K9M S;  5GAG T;  3CC4 R;  1VQL R;  2OTL R;  2ZJP P;  1Q86 S;  1YIT R;  5HL7 P;  1VQ6 R;  1KD1 S;  1VQK R;  3CCL R;  1VQ4 R;  3J7Y T;  1YI2 R;  1Q7Y S;  3PIO P;  1QVF Q;  1M90 S;  3CCM R;  1K8A S;  2ZJQ P;  2QEX R;  3CC7 R;  4WFA P;  1VQP R;  3CCQ R;  4V19 W;  5JVG P;  1S72 R;  4WFB P;  5GAE T;  1VQ7 R;  4WF9 P;  1JJ2 Q;  5H1S U;  1VQM R;  4WCE P;  1KC8 S;  3CME R;  1VQ5 R;  1Q81 S;  4U67 P;  5DM6 P;  3CCV R;  3CD6 R;  3CF5 P;  3CMA R;  1KQS Q;  1YJ9 R;  1Q82 S;  1K73 S;  2ZJR P;  2OTJ R;  1BXE A;  1YIJ R;  3G71 R;  1VQO R;  3CCR R;  4IOC P;  1NJI S;  1YJN R;  1YJW R;  3CCE R;  3PIP P;  1N8R S;  1M1K S;  1VQN R;  1I4J A;  1QVG Q;  3CXC Q;  3I55 R;  3G4S R;  5MLC U;  3CC2 R;  3J7Z S;  4WFN P;  1VQ9 R;  3CCU R;  3CCJ R; 
#chains in the Genus database with same CATH topology
 1YHQ R;  5GAH T;  3H7Q A;  1FTE A;  5GAD T;  1VQ8 R;  5JVH P;  3DLL P;  1NBW A;  5DM7 P;  3CPW Q;  2QA4 R;  4UY8 S;  1W2B Q;  3I56 R;  2BYD A;  3OW2 Q;  3G6E R;  4IOA P;  4IO9 P;  3NFD A;  3CCS R;  1K9M S;  4HC6 A;  5GAG T;  1F7L A;  3CC4 R;  1VQL R;  2OTL R;  3NE1 A;  2JBZ A;  2ZJP P;  1Q86 S;  1YIT R;  5HL7 P;  1VQ6 R;  1KD1 S;  1VQK R;  2D0P A;  3CCL R;  3HQJ A;  1VQ4 R;  3J7Y T;  2WAS B;  1YI2 R;  2JCA A;  1F7T A;  1Q7Y S;  3PIO P;  5CXD A;  2CG5 A;  1M90 S;  1QVF Q;  1FTF A;  3CCM R;  1K8A S;  2ZJQ P;  2QEX R;  3CC7 R;  4DXE A;  4WFA P;  1VQP R;  3CCQ R;  4V19 W;  4MRT A;  5JVG P;  1S72 R;  2WDO A;  4WFB P;  3NE9 A;  5GAE T;  1VQ7 R;  4WF9 P;  1JJ2 Q;  2WDS A;  5H1S U;  2WAS A;  3NE3 B;  4JM7 A;  1VQM R;  4WCE P;  1KC8 S;  1F80 A;  2C43 A;  3CME R;  1VQ5 R;  1Q81 S;  4U67 P;  5DM6 P;  3CCV R;  3CD6 R;  3CF5 P;  2D0O A;  3GWM A;  3CMA R;  1KQS Q;  1YJ9 R;  1Q82 S;  1K73 S;  2ZJR P;  2OTJ R;  2QG8 A;  3QMN A;  1BXE A;  1YIJ R;  3G71 R;  1VQO R;  3CCR R;  5CMO A;  4IOC P;  1FTH A;  1NJI S;  1YJN R;  2WDY A;  1QR0 A;  1YJW R;  3CCE R;  3PIP P;  1N8R S;  3HYK A;  1M1K S;  1VQN R;  1I4J A;  1QVG Q;  3CXC Q;  3I55 R;  3G4S R;  5MLC U;  3CC2 R;  3J7Z S;  4WFN P;  2WAT A;  2BDD A;  1VQ9 R;  3CCU R;  3CCJ R; 
#chains in the Genus database with same CATH homology
 1YHQ R;  5GAH T;  5GAD T;  1VQ8 R;  5JVH P;  3DLL P;  3CPW Q;  5DM7 P;  2QA4 R;  4UY8 S;  1W2B Q;  3I56 R;  3OW2 Q;  3G6E R;  4IOA P;  4IO9 P;  3CCS R;  1K9M S;  5GAG T;  3CC4 R;  1VQL R;  2OTL R;  2ZJP P;  1Q86 S;  1YIT R;  5HL7 P;  1VQ6 R;  1KD1 S;  1VQK R;  3CCL R;  1VQ4 R;  3J7Y T;  1YI2 R;  1Q7Y S;  3PIO P;  1QVF Q;  1M90 S;  3CCM R;  1K8A S;  2ZJQ P;  2QEX R;  3CC7 R;  4WFA P;  1VQP R;  3CCQ R;  4V19 W;  5JVG P;  1S72 R;  4WFB P;  5GAE T;  1VQ7 R;  4WF9 P;  1JJ2 Q;  5H1S U;  1VQM R;  4WCE P;  1KC8 S;  3CME R;  1VQ5 R;  1Q81 S;  4U67 P;  5DM6 P;  3CCV R;  3CD6 R;  3CF5 P;  3CMA R;  1KQS Q;  1YJ9 R;  1Q82 S;  1K73 S;  2ZJR P;  2OTJ R;  1BXE A;  1YIJ R;  3G71 R;  1VQO R;  3CCR R;  4IOC P;  1NJI S;  1YJN R;  1YJW R;  3CCE R;  3PIP P;  1N8R S;  1M1K S;  1VQN R;  1I4J A;  1QVG Q;  3CXC Q;  3I55 R;  3G4S R;  5MLC U;  3CC2 R;  3J7Z S;  4WFN P;  1VQ9 R;  3CCU R;  3CCJ R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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