3CCSR

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2482a
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 37
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 3ccsR00
3CC2R 5DM6P 2ZJQP 1M90S 3CCLR 1YJ9R 4IOCP 1VQKR 3PIOP 3I55R 3CD6R 4V19W 1QVGQ 3CCRR 4IO9P 1YHQR 4U67P 5JVHP 1Q81S 3OW2Q 1VQ4R 3CCMR 1VQPR 5GADT 5HL7P 1VQ9R 1YJWR 1K8AS 3G71R 4WCEP 3CCER 3G6ER 3J7ZS 1YI2R 1VQ5R 2ZJPP 1W2BQ 3J7YT 5GAHT 3CCJR 1KD1S 3PIPP 5MLCU 1N8RS 3DLLP 4WF9P 3CCSR 1S72R 1YIJR 1Q86S 3CC7R 5JVGP 1VQ7R 4IOAP 3CMER 3I56R 2OTJR 5GAGT 1VQLR 4WFNP 2QA4R 1M1KS 1KC8S 1JJ2Q 1KQSQ 3CPWQ 1VQ6R 3CMAR 5DM7P 4WFBP 2ZJRP 1Q7YS 1QVFQ 1I4JA 3CCQR 1VQMR 3CCUR 1VQOR 1VQNR 3CCVR 2OTLR 1Q82S 3G4SR 3CF5P 1K9MS 1NJIS 4UY8S 3CC4R 3CXCQ 1YJNR 1YITR 4WFAP 5H1SU 2QEXR 5GAET 1K73S 1VQ8R 1BXEA
chains in the Genus database with same CATH superfamily
3CC2R 2BYDA 5DM6P 2ZJQP 1M90S 3CCLR 1YJ9R 2CG5A 4IOCP 1FTFA 1VQKR 3PIOP 2WDYA 3I55R 3QMNA 3CD6R 3GWMA 4V19W 1QVGQ 1QR0A 3CCRR 4IO9P 1YHQR 4U67P 5JVHP 1Q81S 3OW2Q 1VQ4R 3CCMR 3HYKA 1FTHA 1VQPR 1NBWA 5GADT 5HL7P 1VQ9R 1YJWR 1K8AS 1FTEA 3G71R 4WCEP 3CCER 3G6ER 3J7ZS 1YI2R 1VQ5R 3NE1A 2ZJPP 1W2BQ 2WDOA 3J7YT 5GAHT 2BDDA 2WASA 3CCJR 1KD1S 3PIPP 5MLCU 1N8RS 5CMOA 3NE9A 3DLLP 2D0OA 4WF9P 3CCSR 1S72R 1YIJR 3NFDA 4JM7A 1Q86S 3CC7R 5JVGP 2WASB 1VQ7R 1F80A 4IOAP 3HQJA 2C43A 3CMER 3I56R 3H7QA 2JCAA 2OTJR 5GAGT 1VQLR 2WDSA 2WATA 4WFNP 2QA4R 1M1KS 1KC8S 1JJ2Q 1KQSQ 3CPWQ 1VQ6R 4MRTA 3CMAR 5DM7P 2QG8A 4WFBP 2ZJRP 1Q7YS 1QVFQ 1I4JA 3CCQR 1VQMR 3CCUR 1VQOR 1VQNR 1F7LA 3CCVR 2OTLR 1Q82S 3G4SR 3CF5P 1K9MS 3NE3B 2JBZA 1NJIS 2D0PA 4HC6A 4DXEA 4UY8S 3CC4R 3CXCQ 1YJNR 1YITR 4WFAP 5CXDA 5H1SU 2QEXR 1F7TA 5GAET 1K73S 1VQ8R 1BXEA
chains in the Genus database with same CATH topology
3CC2R 5DM6P 2ZJQP 1M90S 3CCLR 1YJ9R 4IOCP 1VQKR 3PIOP 3I55R 3CD6R 4V19W 1QVGQ 3CCRR 4IO9P 1YHQR 4U67P 5JVHP 1Q81S 3OW2Q 1VQ4R 3CCMR 1VQPR 5GADT 5HL7P 1VQ9R 1YJWR 1K8AS 3G71R 4WCEP 3CCER 3G6ER 3J7ZS 1YI2R 1VQ5R 2ZJPP 1W2BQ 3J7YT 5GAHT 3CCJR 1KD1S 3PIPP 5MLCU 1N8RS 3DLLP 4WF9P 3CCSR 1S72R 1YIJR 1Q86S 3CC7R 5JVGP 1VQ7R 4IOAP 3CMER 3I56R 2OTJR 5GAGT 1VQLR 4WFNP 2QA4R 1M1KS 1KC8S 1JJ2Q 1KQSQ 3CPWQ 1VQ6R 3CMAR 5DM7P 4WFBP 2ZJRP 1Q7YS 1QVFQ 1I4JA 3CCQR 1VQMR 3CCUR 1VQOR 1VQNR 3CCVR 2OTLR 1Q82S 3G4SR 3CF5P 1K9MS 1NJIS 4UY8S 3CC4R 3CXCQ 1YJNR 1YITR 4WFAP 5H1SU 2QEXR 5GAET 1K73S 1VQ8R 1BXEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CC2 R;  5DM6 P;  2ZJQ P;  1M90 S;  3CCL R;  1YJ9 R;  4IOC P;  1VQK R;  3PIO P;  3I55 R;  3CD6 R;  4V19 W;  1QVG Q;  3CCR R;  4IO9 P;  1YHQ R;  4U67 P;  5JVH P;  1Q81 S;  3OW2 Q;  1VQ4 R;  3CCM R;  1VQP R;  5GAD T;  5HL7 P;  1VQ9 R;  1YJW R;  1K8A S;  3G71 R;  4WCE P;  3CCE R;  3G6E R;  3J7Z S;  1YI2 R;  1VQ5 R;  2ZJP P;  1W2B Q;  3J7Y T;  5GAH T;  3CCJ R;  1KD1 S;  3PIP P;  5MLC U;  1N8R S;  3DLL P;  4WF9 P;  3CCS R;  1S72 R;  1YIJ R;  1Q86 S;  3CC7 R;  5JVG P;  1VQ7 R;  4IOA P;  3CME R;  3I56 R;  2OTJ R;  5GAG T;  1VQL R;  4WFN P;  2QA4 R;  1M1K S;  1KC8 S;  1JJ2 Q;  1KQS Q;  3CPW Q;  1VQ6 R;  3CMA R;  5DM7 P;  4WFB P;  2ZJR P;  1Q7Y S;  1QVF Q;  1I4J A;  3CCQ R;  1VQM R;  3CCU R;  1VQO R;  1VQN R;  3CCV R;  2OTL R;  1Q82 S;  3G4S R;  3CF5 P;  1K9M S;  1NJI S;  4UY8 S;  3CC4 R;  3CXC Q;  1YJN R;  1YIT R;  4WFA P;  5H1S U;  2QEX R;  5GAE T;  1K73 S;  1VQ8 R;  1BXE A; 
#chains in the Genus database with same CATH topology
 3CC2 R;  2BYD A;  5DM6 P;  2ZJQ P;  1M90 S;  3CCL R;  1YJ9 R;  2CG5 A;  4IOC P;  1FTF A;  1VQK R;  3PIO P;  2WDY A;  3I55 R;  3QMN A;  3CD6 R;  3GWM A;  4V19 W;  1QVG Q;  1QR0 A;  3CCR R;  4IO9 P;  1YHQ R;  4U67 P;  5JVH P;  1Q81 S;  3OW2 Q;  1VQ4 R;  3CCM R;  3HYK A;  1FTH A;  1VQP R;  1NBW A;  5GAD T;  5HL7 P;  1VQ9 R;  1YJW R;  1K8A S;  1FTE A;  3G71 R;  4WCE P;  3CCE R;  3G6E R;  3J7Z S;  1YI2 R;  1VQ5 R;  3NE1 A;  2ZJP P;  1W2B Q;  2WDO A;  3J7Y T;  5GAH T;  2BDD A;  2WAS A;  3CCJ R;  1KD1 S;  3PIP P;  5MLC U;  1N8R S;  5CMO A;  3NE9 A;  3DLL P;  2D0O A;  4WF9 P;  3CCS R;  1S72 R;  1YIJ R;  3NFD A;  4JM7 A;  1Q86 S;  3CC7 R;  5JVG P;  2WAS B;  1VQ7 R;  1F80 A;  4IOA P;  3HQJ A;  2C43 A;  3CME R;  3I56 R;  3H7Q A;  2JCA A;  2OTJ R;  5GAG T;  1VQL R;  2WDS A;  2WAT A;  4WFN P;  2QA4 R;  1M1K S;  1KC8 S;  1JJ2 Q;  1KQS Q;  3CPW Q;  1VQ6 R;  4MRT A;  3CMA R;  5DM7 P;  2QG8 A;  4WFB P;  2ZJR P;  1Q7Y S;  1QVF Q;  1I4J A;  3CCQ R;  1VQM R;  3CCU R;  1VQO R;  1VQN R;  1F7L A;  3CCV R;  2OTL R;  1Q82 S;  3G4S R;  3CF5 P;  1K9M S;  3NE3 B;  2JBZ A;  1NJI S;  2D0P A;  4HC6 A;  4DXE A;  4UY8 S;  3CC4 R;  3CXC Q;  1YJN R;  1YIT R;  4WFA P;  5CXD A;  5H1S U;  2QEX R;  1F7T A;  5GAE T;  1K73 S;  1VQ8 R;  1BXE A; 
#chains in the Genus database with same CATH homology
 3CC2 R;  5DM6 P;  2ZJQ P;  1M90 S;  3CCL R;  1YJ9 R;  4IOC P;  1VQK R;  3PIO P;  3I55 R;  3CD6 R;  4V19 W;  1QVG Q;  3CCR R;  4IO9 P;  1YHQ R;  4U67 P;  5JVH P;  1Q81 S;  3OW2 Q;  1VQ4 R;  3CCM R;  1VQP R;  5GAD T;  5HL7 P;  1VQ9 R;  1YJW R;  1K8A S;  3G71 R;  4WCE P;  3CCE R;  3G6E R;  3J7Z S;  1YI2 R;  1VQ5 R;  2ZJP P;  1W2B Q;  3J7Y T;  5GAH T;  3CCJ R;  1KD1 S;  3PIP P;  5MLC U;  1N8R S;  3DLL P;  4WF9 P;  3CCS R;  1S72 R;  1YIJ R;  1Q86 S;  3CC7 R;  5JVG P;  1VQ7 R;  4IOA P;  3CME R;  3I56 R;  2OTJ R;  5GAG T;  1VQL R;  4WFN P;  2QA4 R;  1M1K S;  1KC8 S;  1JJ2 Q;  1KQS Q;  3CPW Q;  1VQ6 R;  3CMA R;  5DM7 P;  4WFB P;  2ZJR P;  1Q7Y S;  1QVF Q;  1I4J A;  3CCQ R;  1VQM R;  3CCU R;  1VQO R;  1VQN R;  3CCV R;  2OTL R;  1Q82 S;  3G4S R;  3CF5 P;  1K9M S;  1NJI S;  4UY8 S;  3CC4 R;  3CXC Q;  1YJN R;  1YIT R;  4WFA P;  5H1S U;  2QEX R;  5GAE T;  1K73 S;  1VQ8 R;  1BXE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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