3CPWQ

The structure of the antibiotic linezolid bound to the large ribosomal subunit of haloarcula marismortui
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S RIBOSOMAL RNA
total genus 37
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2008-04-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
Q PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 3cpwQ00
5MLCU 3CCLR 5DM7P 2QA4R 1VQ8R 4V19W 1N8RS 3CMER 5JVHP 5GAHT 3CCMR 3CCRR 4WCEP 3G6ER 1YJNR 5GAGT 1YIJR 1YHQR 3CC4R 1M90S 4WFBP 3CCQR 1VQPR 3CD6R 3J7ZS 1Q81S 2OTJR 1VQ6R 1KC8S 3CC7R 1VQLR 3CMAR 4IO9P 1VQ5R 3G4SR 1M1KS 1Q82S 1VQ4R 3CCJR 3CCER 1S72R 1QVFQ 4WFAP 4IOCP 1VQMR 5GADT 3CCUR 1NJIS 1Q7YS 1VQ9R 1YJ9R 1YJWR 1K9MS 5HL7P 3DLLP 2ZJRP 3J7YT 3I55R 4UY8S 3CCSR 1VQKR 3I56R 5H1SU 1QVGQ 1KD1S 1VQNR 3PIOP 1K73S 1I4JA 4IOAP 3G71R 1KQSQ 5JVGP 4WF9P 1YITR 1BXEA 2OTLR 3CF5P 5DM6P 3OW2Q 3CC2R 1W2BQ 3CCVR 5GAET 3CXCQ 3PIPP 4WFNP 1VQ7R 1K8AS 2ZJPP 1VQOR 1Q86S 1JJ2Q 3CPWQ 4U67P 1YI2R 2ZJQP 2QEXR
chains in the Genus database with same CATH superfamily
5MLCU 3CCLR 5DM7P 1F80A 2QA4R 2WASA 1VQ8R 4V19W 1N8RS 2JCAA 3CMER 2C43A 5JVHP 4HC6A 4MRTA 3CCRR 5GAHT 3CCMR 4WCEP 3G6ER 1YJNR 2WDOA 5GAGT 1YIJR 2D0OA 1YHQR 3CC4R 1M90S 4WFBP 3CCQR 1VQPR 3CD6R 3J7ZS 1Q81S 2OTJR 2WATA 1QR0A 1VQ6R 1KC8S 3CC7R 1VQLR 3CMAR 4IO9P 1VQ5R 3G4SR 1M1KS 1Q82S 1VQ4R 3CCJR 3CCER 3H7QA 1S72R 1FTFA 3HYKA 1QVFQ 4WFAP 4IOCP 1VQMR 2WDSA 3NE9A 5GADT 3CCUR 3NE1A 5CXDA 1NJIS 1Q7YS 1VQ9R 1YJ9R 1YJWR 1K9MS 5HL7P 3DLLP 2ZJRP 4DXEA 3J7YT 1FTHA 3I55R 4UY8S 3CCSR 1VQKR 3I56R 2WASB 3NFDA 2JBZA 2BYDA 5H1SU 2QG8A 1NBWA 5CMOA 4JM7A 1QVGQ 1KD1S 1VQNR 3PIOP 3QMNA 3HQJA 1K73S 1F7TA 1I4JA 4IOAP 3G71R 2CG5A 1KQSQ 4WF9P 5JVGP 1YITR 1BXEA 2OTLR 3CF5P 5DM6P 3OW2Q 3CC2R 1W2BQ 3NE3B 1FTEA 3CCVR 5GAET 3CXCQ 3GWMA 3PIPP 4WFNP 1VQ7R 2D0PA 1K8AS 1F7LA 2BDDA 2ZJPP 1VQOR 1Q86S 1JJ2Q 2WDYA 3CPWQ 4U67P 1YI2R 2ZJQP 2QEXR
chains in the Genus database with same CATH topology
5MLCU 3CCLR 5DM7P 2QA4R 1VQ8R 4V19W 1N8RS 3CMER 5JVHP 5GAHT 3CCMR 3CCRR 4WCEP 3G6ER 1YJNR 5GAGT 1YIJR 1YHQR 3CC4R 1M90S 4WFBP 3CCQR 1VQPR 3CD6R 3J7ZS 1Q81S 2OTJR 1VQ6R 1KC8S 3CC7R 1VQLR 3CMAR 4IO9P 1VQ5R 3G4SR 1M1KS 1Q82S 1VQ4R 3CCJR 3CCER 1S72R 1QVFQ 4WFAP 4IOCP 1VQMR 5GADT 3CCUR 1NJIS 1Q7YS 1VQ9R 1YJ9R 1YJWR 1K9MS 5HL7P 3DLLP 2ZJRP 3J7YT 3I55R 4UY8S 3CCSR 1VQKR 3I56R 5H1SU 1QVGQ 1KD1S 1VQNR 3PIOP 1K73S 1I4JA 4IOAP 3G71R 1KQSQ 5JVGP 4WF9P 1YITR 1BXEA 2OTLR 3CF5P 5DM6P 3OW2Q 3CC2R 1W2BQ 3CCVR 5GAET 3CXCQ 3PIPP 4WFNP 1VQ7R 1K8AS 2ZJPP 1VQOR 1Q86S 1JJ2Q 3CPWQ 4U67P 1YI2R 2ZJQP 2QEXR
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5MLC U;  3CCL R;  5DM7 P;  2QA4 R;  1VQ8 R;  4V19 W;  1N8R S;  3CME R;  5JVH P;  5GAH T;  3CCM R;  3CCR R;  4WCE P;  3G6E R;  1YJN R;  5GAG T;  1YIJ R;  1YHQ R;  3CC4 R;  1M90 S;  4WFB P;  3CCQ R;  1VQP R;  3CD6 R;  3J7Z S;  1Q81 S;  2OTJ R;  1VQ6 R;  1KC8 S;  3CC7 R;  1VQL R;  3CMA R;  4IO9 P;  1VQ5 R;  3G4S R;  1M1K S;  1Q82 S;  1VQ4 R;  3CCJ R;  3CCE R;  1S72 R;  1QVF Q;  4WFA P;  4IOC P;  1VQM R;  5GAD T;  3CCU R;  1NJI S;  1Q7Y S;  1VQ9 R;  1YJ9 R;  1YJW R;  1K9M S;  5HL7 P;  3DLL P;  2ZJR P;  3J7Y T;  3I55 R;  4UY8 S;  3CCS R;  1VQK R;  3I56 R;  5H1S U;  1QVG Q;  1KD1 S;  1VQN R;  3PIO P;  1K73 S;  1I4J A;  4IOA P;  3G71 R;  1KQS Q;  5JVG P;  4WF9 P;  1YIT R;  1BXE A;  2OTL R;  3CF5 P;  5DM6 P;  3OW2 Q;  3CC2 R;  1W2B Q;  3CCV R;  5GAE T;  3CXC Q;  3PIP P;  4WFN P;  1VQ7 R;  1K8A S;  2ZJP P;  1VQO R;  1Q86 S;  1JJ2 Q;  3CPW Q;  4U67 P;  1YI2 R;  2ZJQ P;  2QEX R; 
#chains in the Genus database with same CATH topology
 5MLC U;  3CCL R;  5DM7 P;  1F80 A;  2QA4 R;  2WAS A;  1VQ8 R;  4V19 W;  1N8R S;  2JCA A;  3CME R;  2C43 A;  5JVH P;  4HC6 A;  4MRT A;  3CCR R;  5GAH T;  3CCM R;  4WCE P;  3G6E R;  1YJN R;  2WDO A;  5GAG T;  1YIJ R;  2D0O A;  1YHQ R;  3CC4 R;  1M90 S;  4WFB P;  3CCQ R;  1VQP R;  3CD6 R;  3J7Z S;  1Q81 S;  2OTJ R;  2WAT A;  1QR0 A;  1VQ6 R;  1KC8 S;  3CC7 R;  1VQL R;  3CMA R;  4IO9 P;  1VQ5 R;  3G4S R;  1M1K S;  1Q82 S;  1VQ4 R;  3CCJ R;  3CCE R;  3H7Q A;  1S72 R;  1FTF A;  3HYK A;  1QVF Q;  4WFA P;  4IOC P;  1VQM R;  2WDS A;  3NE9 A;  5GAD T;  3CCU R;  3NE1 A;  5CXD A;  1NJI S;  1Q7Y S;  1VQ9 R;  1YJ9 R;  1YJW R;  1K9M S;  5HL7 P;  3DLL P;  2ZJR P;  4DXE A;  3J7Y T;  1FTH A;  3I55 R;  4UY8 S;  3CCS R;  1VQK R;  3I56 R;  2WAS B;  3NFD A;  2JBZ A;  2BYD A;  5H1S U;  2QG8 A;  1NBW A;  5CMO A;  4JM7 A;  1QVG Q;  1KD1 S;  1VQN R;  3PIO P;  3QMN A;  3HQJ A;  1K73 S;  1F7T A;  1I4J A;  4IOA P;  3G71 R;  2CG5 A;  1KQS Q;  4WF9 P;  5JVG P;  1YIT R;  1BXE A;  2OTL R;  3CF5 P;  5DM6 P;  3OW2 Q;  3CC2 R;  1W2B Q;  3NE3 B;  1FTE A;  3CCV R;  5GAE T;  3CXC Q;  3GWM A;  3PIP P;  4WFN P;  1VQ7 R;  2D0P A;  1K8A S;  1F7L A;  2BDD A;  2ZJP P;  1VQO R;  1Q86 S;  1JJ2 Q;  2WDY A;  3CPW Q;  4U67 P;  1YI2 R;  2ZJQ P;  2QEX R; 
#chains in the Genus database with same CATH homology
 5MLC U;  3CCL R;  5DM7 P;  2QA4 R;  1VQ8 R;  4V19 W;  1N8R S;  3CME R;  5JVH P;  5GAH T;  3CCM R;  3CCR R;  4WCE P;  3G6E R;  1YJN R;  5GAG T;  1YIJ R;  1YHQ R;  3CC4 R;  1M90 S;  4WFB P;  3CCQ R;  1VQP R;  3CD6 R;  3J7Z S;  1Q81 S;  2OTJ R;  1VQ6 R;  1KC8 S;  3CC7 R;  1VQL R;  3CMA R;  4IO9 P;  1VQ5 R;  3G4S R;  1M1K S;  1Q82 S;  1VQ4 R;  3CCJ R;  3CCE R;  1S72 R;  1QVF Q;  4WFA P;  4IOC P;  1VQM R;  5GAD T;  3CCU R;  1NJI S;  1Q7Y S;  1VQ9 R;  1YJ9 R;  1YJW R;  1K9M S;  5HL7 P;  3DLL P;  2ZJR P;  3J7Y T;  3I55 R;  4UY8 S;  3CCS R;  1VQK R;  3I56 R;  5H1S U;  1QVG Q;  1KD1 S;  1VQN R;  3PIO P;  1K73 S;  1I4J A;  4IOA P;  3G71 R;  1KQS Q;  5JVG P;  4WF9 P;  1YIT R;  1BXE A;  2OTL R;  3CF5 P;  5DM6 P;  3OW2 Q;  3CC2 R;  1W2B Q;  3CCV R;  5GAE T;  3CXC Q;  3PIP P;  4WFN P;  1VQ7 R;  1K8A S;  2ZJP P;  1VQO R;  1Q86 S;  1JJ2 Q;  3CPW Q;  4U67 P;  1YI2 R;  2ZJQ P;  2QEX R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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