3D1MA

Crystal structure of sonic hedgehog bound to the third fniii domain of cdo
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
148
structure length
148
Chain Sequence
TPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHCSVKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein / cell adhesion
source organism Mus musculus
publication title The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla.
pubmed doi rcsb
molecule keywords Sonic hedgehog protein
total genus 45
structure length 148
sequence length 148
chains with identical sequence B
ec nomenclature
pdb deposition date 2008-05-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1380.10 Alpha Beta 2-Layer Sandwich Muramoyl-pentapeptide Carboxypeptidase; domain 2 Muramoyl-pentapeptide Carboxypeptidase; domain 2 3d1mA00
1R44A 2WFRA 4OXDA 4MUSA 4C4MA 3N1OA 3HO5H 1TZPA 1VHHA 4NT9A 3N1GA 4MPHA 3N1PB 4OX5A 4OAKA 4F78A 3N1RA 1U10A 4OX3A 3K7JB 2WFXA 2IBGE 4D0YA 2WG4A 2VO9A 3MXWA 3K7HB 5HNMA 4MURA 3N1MB 2WG3A 3M1NA 3K7GB 3N1QA 4MUQA 2WFQA 4C4NA 4JIDA 3N1FA 4MUTA 3D1MA 3K7IB 1LBUA
chains in the Genus database with same CATH superfamily
1R44A 2WFRA 4OXDA 1WC9A 4MUSA 4C4MA 2CFHA 3N1OA 2CFHC 3CUEB 1VHHA 1TZPA 3HO5H 4NT9A 3N1GA 4MPHA 2J3WD 3N1PB 4OX5A 4OAKA 4F78A 3N1RA 1U10A 4OX3A 3K7JB 2C0JB 3NJCA 2WFXA 2IBGE 4D0YA 2VO9A 2WG4A 3MXWA 3K7HB 5HNMA 4MURA 2PWNA 2WG3A 3KXCC 3N1MB 2C0JA 3KXCA 3M1NA 3K7GB 2J3WB 2J3TB 2OSOA 1SZ7A 3N1QA 4MUQA 2J3RB 2WFQA 4C4NA 3CUED 4JIDA 2J3TA 2OSDA 3N1FA 4MUTA 3D1MA 3K7IB 2BJNA 2J3RA 1LBUA 1WC8A
chains in the Genus database with same CATH topology
1R44A 2WFRA 4OXDA 4MUSA 4C4MA 3N1OA 3HO5H 1TZPA 1VHHA 4NT9A 3N1GA 4MPHA 3N1PB 4OX5A 4OAKA 4F78A 3N1RA 1U10A 4OX3A 3K7JB 2WFXA 2IBGE 4D0YA 2WG4A 2VO9A 3MXWA 3K7HB 5HNMA 4MURA 3N1MB 2WG3A 3M1NA 3K7GB 3N1QA 4MUQA 2WFQA 4C4NA 4JIDA 3N1FA 4MUTA 3D1MA 3K7IB 1LBUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R44 A;  2WFR A;  4OXD A;  4MUS A;  4C4M A;  3N1O A;  3HO5 H;  1TZP A;  1VHH A;  4NT9 A;  3N1G A;  4MPH A;  3N1P B;  4OX5 A;  4OAK A;  4F78 A;  3N1R A;  1U10 A;  4OX3 A;  3K7J B;  2WFX A;  2IBG E;  4D0Y A;  2WG4 A;  2VO9 A;  3MXW A;  3K7H B;  5HNM A;  4MUR A;  3N1M B;  2WG3 A;  3M1N A;  3K7G B;  3N1Q A;  4MUQ A;  2WFQ A;  4C4N A;  4JID A;  3N1F A;  4MUT A;  3D1M A;  3K7I B;  1LBU A; 
#chains in the Genus database with same CATH topology
 1R44 A;  2WFR A;  4OXD A;  1WC9 A;  4MUS A;  4C4M A;  2CFH A;  3N1O A;  2CFH C;  3CUE B;  1VHH A;  1TZP A;  3HO5 H;  4NT9 A;  3N1G A;  4MPH A;  2J3W D;  3N1P B;  4OX5 A;  4OAK A;  4F78 A;  3N1R A;  1U10 A;  4OX3 A;  3K7J B;  2C0J B;  3NJC A;  2WFX A;  2IBG E;  4D0Y A;  2VO9 A;  2WG4 A;  3MXW A;  3K7H B;  5HNM A;  4MUR A;  2PWN A;  2WG3 A;  3KXC C;  3N1M B;  2C0J A;  3KXC A;  3M1N A;  3K7G B;  2J3W B;  2J3T B;  2OSO A;  1SZ7 A;  3N1Q A;  4MUQ A;  2J3R B;  2WFQ A;  4C4N A;  3CUE D;  4JID A;  2J3T A;  2OSD A;  3N1F A;  4MUT A;  3D1M A;  3K7I B;  2BJN A;  2J3R A;  1LBU A;  1WC8 A; 
#chains in the Genus database with same CATH homology
 1R44 A;  2WFR A;  4OXD A;  4MUS A;  4C4M A;  3N1O A;  3HO5 H;  1TZP A;  1VHH A;  4NT9 A;  3N1G A;  4MPH A;  3N1P B;  4OX5 A;  4OAK A;  4F78 A;  3N1R A;  1U10 A;  4OX3 A;  3K7J B;  2WFX A;  2IBG E;  4D0Y A;  2WG4 A;  2VO9 A;  3MXW A;  3K7H B;  5HNM A;  4MUR A;  3N1M B;  2WG3 A;  3M1N A;  3K7G B;  3N1Q A;  4MUQ A;  2WFQ A;  4C4N A;  4JID A;  3N1F A;  4MUT A;  3D1M A;  3K7I B;  1LBU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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