3D1MA

Crystal structure of sonic hedgehog bound to the third fniii domain of cdo
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
148
structure length
148
Chain Sequence
TPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHCSVKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla.
pubmed doi rcsb
molecule tags Signaling protein / cell adhesion
source organism Mus musculus
molecule keywords Sonic hedgehog protein
total genus 45
structure length 148
sequence length 148
chains with identical sequence B
ec nomenclature
pdb deposition date 2008-05-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1380.10 Alpha Beta 2-Layer Sandwich Muramoyl-pentapeptide Carboxypeptidase; domain 2 Muramoyl-pentapeptide Carboxypeptidase; domain 2 3d1mA00
4MUSA 4C4MA 4MURA 2VO9A 3N1GA 4OX3A 3K7GB 4NT9A 4MPHA 2WFQA 2WFXA 3N1OA 3N1PB 4C4NA 3MXWA 3M1NA 4OAKA 2IBGE 1U10A 5HNMA 2WG4A 1LBUA 1VHHA 4D0YA 2WG3A 4OXDA 3N1RA 4MUTA 3HO5H 4F78A 1TZPA 3K7JB 4JIDA 4OX5A 3D1MA 3N1QA 2WFRA 3N1FA 3K7IB 1R44A 4MUQA 3K7HB 3N1MB
chains in the Genus database with same CATH superfamily
4MUSA 4C4MA 4MURA 2VO9A 1WC9A 2J3WB 3N1GA 4OX3A 1WC8A 3CUED 3K7GB 2J3TB 4NT9A 4MPHA 2WFQA 2WFXA 3N1OA 3N1PB 4C4NA 3MXWA 3M1NA 1SZ7A 2OSOA 2J3WD 4OAKA 2C0JA 1U10A 2IBGE 3NJCA 5HNMA 2WG4A 1LBUA 1VHHA 4D0YA 2WG3A 2J3RA 4OXDA 2PWNA 2CFHC 3N1RA 4MUTA 3KXCC 2BJNA 3HO5H 1TZPA 2CFHA 4F78A 3K7JB 4JIDA 2J3TA 4OX5A 2C0JB 2OSDA 3D1MA 3KXCA 3N1QA 3CUEB 2WFRA 3N1FA 3K7IB 1R44A 4MUQA 3K7HB 2J3RB 3N1MB
chains in the Genus database with same CATH topology
4MUSA 4C4MA 4MURA 2VO9A 3N1GA 4OX3A 3K7GB 4NT9A 4MPHA 2WFQA 2WFXA 3N1OA 3N1PB 4C4NA 3MXWA 3M1NA 4OAKA 2IBGE 1U10A 5HNMA 2WG4A 1LBUA 1VHHA 4D0YA 2WG3A 4OXDA 3N1RA 4MUTA 3HO5H 4F78A 1TZPA 3K7JB 4JIDA 4OX5A 3D1MA 3N1QA 2WFRA 3N1FA 3K7IB 1R44A 4MUQA 3K7HB 3N1MB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MUS A;  4C4M A;  4MUR A;  2VO9 A;  3N1G A;  4OX3 A;  3K7G B;  4NT9 A;  4MPH A;  2WFQ A;  2WFX A;  3N1O A;  3N1P B;  4C4N A;  3MXW A;  3M1N A;  4OAK A;  2IBG E;  1U10 A;  5HNM A;  2WG4 A;  1LBU A;  1VHH A;  4D0Y A;  2WG3 A;  4OXD A;  3N1R A;  4MUT A;  3HO5 H;  4F78 A;  1TZP A;  3K7J B;  4JID A;  4OX5 A;  3D1M A;  3N1Q A;  2WFR A;  3N1F A;  3K7I B;  1R44 A;  4MUQ A;  3K7H B;  3N1M B; 
#chains in the Genus database with same CATH topology
 4MUS A;  4C4M A;  4MUR A;  2VO9 A;  1WC9 A;  2J3W B;  3N1G A;  4OX3 A;  1WC8 A;  3CUE D;  3K7G B;  2J3T B;  4NT9 A;  4MPH A;  2WFQ A;  2WFX A;  3N1O A;  3N1P B;  4C4N A;  3MXW A;  3M1N A;  1SZ7 A;  2OSO A;  2J3W D;  4OAK A;  2C0J A;  1U10 A;  2IBG E;  3NJC A;  5HNM A;  2WG4 A;  1LBU A;  1VHH A;  4D0Y A;  2WG3 A;  2J3R A;  4OXD A;  2PWN A;  2CFH C;  3N1R A;  4MUT A;  3KXC C;  2BJN A;  3HO5 H;  1TZP A;  2CFH A;  4F78 A;  3K7J B;  4JID A;  2J3T A;  4OX5 A;  2C0J B;  2OSD A;  3D1M A;  3KXC A;  3N1Q A;  3CUE B;  2WFR A;  3N1F A;  3K7I B;  1R44 A;  4MUQ A;  3K7H B;  2J3R B;  3N1M B; 
#chains in the Genus database with same CATH homology
 4MUS A;  4C4M A;  4MUR A;  2VO9 A;  3N1G A;  4OX3 A;  3K7G B;  4NT9 A;  4MPH A;  2WFQ A;  2WFX A;  3N1O A;  3N1P B;  4C4N A;  3MXW A;  3M1N A;  4OAK A;  2IBG E;  1U10 A;  5HNM A;  2WG4 A;  1LBU A;  1VHH A;  4D0Y A;  2WG3 A;  4OXD A;  3N1R A;  4MUT A;  3HO5 H;  4F78 A;  1TZP A;  3K7J B;  4JID A;  4OX5 A;  3D1M A;  3N1Q A;  2WFR A;  3N1F A;  3K7I B;  1R44 A;  4MUQ A;  3K7H B;  3N1M B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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