3HO5H

Crystal structure of hedgehog-interacting protein (hhip) and sonic hedgehog (shh) complex
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
154
structure length
154
Chain Sequence
KLTPLAYKQFIPNVAEKTLGASGRYEGKISRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHCSVKAENSV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Hedgehog-interacting protein
total genus 38
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2009-06-01
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1380.10 Alpha Beta 2-Layer Sandwich Muramoyl-pentapeptide Carboxypeptidase; domain 2 Muramoyl-pentapeptide Carboxypeptidase; domain 2 3ho5H00
2WFQA 3N1RA 3K7JB 4C4MA 3N1PB 1VHHA 3HO5H 4NT9A 4JIDA 2VO9A 4C4NA 4OXDA 3K7IB 1U10A 1R44A 4MUQA 4D0YA 3K7HB 3N1QA 3D1MA 2IBGE 3N1GA 4MURA 3MXWA 4MUTA 2WG3A 4OX5A 2WFRA 3K7GB 4MUSA 4OX3A 4OAKA 1LBUA 1TZPA 2WG4A 4MPHA 3N1MB 2WFXA 3N1OA 3M1NA 3N1FA 5HNMA 4F78A
chains in the Genus database with same CATH superfamily
2WFQA 3N1RA 3K7JB 4C4MA 2C0JB 3N1PB 1VHHA 1SZ7A 3HO5H 4NT9A 4JIDA 2VO9A 4C4NA 4OXDA 2J3TB 2J3RB 2OSDA 3K7IB 1U10A 1WC9A 1R44A 2BJNA 4MUQA 3K7HB 4D0YA 3N1QA 3D1MA 2CFHA 3KXCA 2IBGE 2J3WB 3CUED 3N1GA 4MURA 2OSOA 3MXWA 2C0JA 2CFHC 2WG3A 3KXCC 4MUTA 4OX5A 2WFRA 3K7GB 4MUSA 4OX3A 4OAKA 2J3TA 2J3RA 1LBUA 1TZPA 1WC8A 2WG4A 4MPHA 3N1MB 2WFXA 3N1OA 2J3WD 3NJCA 2PWNA 3M1NA 3N1FA 3CUEB 5HNMA 4F78A
chains in the Genus database with same CATH topology
2WFQA 3N1RA 3K7JB 4C4MA 3N1PB 1VHHA 3HO5H 4NT9A 4JIDA 2VO9A 4C4NA 4OXDA 3K7IB 1U10A 1R44A 4MUQA 4D0YA 3K7HB 3N1QA 3D1MA 2IBGE 3N1GA 4MURA 3MXWA 4MUTA 2WG3A 4OX5A 2WFRA 3K7GB 4MUSA 4OX3A 4OAKA 1LBUA 1TZPA 2WG4A 4MPHA 3N1MB 2WFXA 3N1OA 3M1NA 3N1FA 5HNMA 4F78A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WFQ A;  3N1R A;  3K7J B;  4C4M A;  3N1P B;  1VHH A;  3HO5 H;  4NT9 A;  4JID A;  2VO9 A;  4C4N A;  4OXD A;  3K7I B;  1U10 A;  1R44 A;  4MUQ A;  4D0Y A;  3K7H B;  3N1Q A;  3D1M A;  2IBG E;  3N1G A;  4MUR A;  3MXW A;  4MUT A;  2WG3 A;  4OX5 A;  2WFR A;  3K7G B;  4MUS A;  4OX3 A;  4OAK A;  1LBU A;  1TZP A;  2WG4 A;  4MPH A;  3N1M B;  2WFX A;  3N1O A;  3M1N A;  3N1F A;  5HNM A;  4F78 A; 
#chains in the Genus database with same CATH topology
 2WFQ A;  3N1R A;  3K7J B;  4C4M A;  2C0J B;  3N1P B;  1VHH A;  1SZ7 A;  3HO5 H;  4NT9 A;  4JID A;  2VO9 A;  4C4N A;  4OXD A;  2J3T B;  2J3R B;  2OSD A;  3K7I B;  1U10 A;  1WC9 A;  1R44 A;  2BJN A;  4MUQ A;  3K7H B;  4D0Y A;  3N1Q A;  3D1M A;  2CFH A;  3KXC A;  2IBG E;  2J3W B;  3CUE D;  3N1G A;  4MUR A;  2OSO A;  3MXW A;  2C0J A;  2CFH C;  2WG3 A;  3KXC C;  4MUT A;  4OX5 A;  2WFR A;  3K7G B;  4MUS A;  4OX3 A;  4OAK A;  2J3T A;  2J3R A;  1LBU A;  1TZP A;  1WC8 A;  2WG4 A;  4MPH A;  3N1M B;  2WFX A;  3N1O A;  2J3W D;  3NJC A;  2PWN A;  3M1N A;  3N1F A;  3CUE B;  5HNM A;  4F78 A; 
#chains in the Genus database with same CATH homology
 2WFQ A;  3N1R A;  3K7J B;  4C4M A;  3N1P B;  1VHH A;  3HO5 H;  4NT9 A;  4JID A;  2VO9 A;  4C4N A;  4OXD A;  3K7I B;  1U10 A;  1R44 A;  4MUQ A;  4D0Y A;  3K7H B;  3N1Q A;  3D1M A;  2IBG E;  3N1G A;  4MUR A;  3MXW A;  4MUT A;  2WG3 A;  4OX5 A;  2WFR A;  3K7G B;  4MUS A;  4OX3 A;  4OAK A;  1LBU A;  1TZP A;  2WG4 A;  4MPH A;  3N1M B;  2WFX A;  3N1O A;  3M1N A;  3N1F A;  5HNM A;  4F78 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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