3K7GB

Crystal structure of the indian hedgehog n-terminal signalling domain
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
157
structure length
157
Chain Sequence
PRKLVPLAYKQFSPNVPEKTLGASGRYEGKIARSSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDRLNSLAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYGLLARLAVEAGFDWVYYESKAHVHCSVKSEHSAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the Indian Hedgehog N-terminal signalling domain
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Indian hedgehog protein
total genus 46
structure length 157
sequence length 157
ec nomenclature
pdb deposition date 2009-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01085 HH_signal Hedgehog amino-terminal signalling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1380.10 Alpha Beta 2-Layer Sandwich Muramoyl-pentapeptide Carboxypeptidase; domain 2 Muramoyl-pentapeptide Carboxypeptidase; domain 2 3k7gB00
4D0YA 3K7GB 3N1RA 4NT9A 3N1GA 4OX5A 1VHHA 2WG4A 1R44A 2WFRA 4F78A 2WG3A 2WFQA 5HNMA 4MPHA 4MURA 2WFXA 4MUSA 3N1PB 3MXWA 4OX3A 4MUTA 3HO5H 1TZPA 4C4NA 3N1MB 4C4MA 4MUQA 4OAKA 3K7HB 3K7IB 4JIDA 2VO9A 3N1OA 1LBUA 1U10A 3D1MA 3N1QA 4OXDA 3K7JB 3N1FA 2IBGE 3M1NA
chains in the Genus database with same CATH superfamily
4D0YA 3K7GB 3N1RA 4NT9A 3N1GA 2J3RA 2J3TA 4OX5A 1VHHA 2WG4A 1SZ7A 3CUED 2WFRA 3M1NA 4F78A 3KXCC 2WG3A 2WFQA 5HNMA 4MPHA 4MURA 2J3WD 2OSOA 2WFXA 4MUSA 3N1PB 3MXWA 3CUEB 4OX3A 2CFHC 4MUTA 3HO5H 1TZPA 4C4NA 2OSDA 3N1MB 3KXCA 3NJCA 2J3WB 3K7IB 3K7HB 4JIDA 2VO9A 4MUQA 4OAKA 4C4MA 2PWNA 3N1OA 1LBUA 1U10A 3D1MA 3N1QA 4OXDA 2CFHA 1WC8A 2C0JB 2BJNA 3K7JB 2J3RB 2J3TB 3N1FA 2IBGE 1WC9A 2C0JA 1R44A
chains in the Genus database with same CATH topology
4D0YA 3K7GB 3N1RA 4NT9A 3N1GA 4OX5A 1VHHA 2WG4A 1R44A 2WFRA 4F78A 2WG3A 2WFQA 5HNMA 4MPHA 4MURA 2WFXA 4MUSA 3N1PB 3MXWA 4OX3A 4MUTA 3HO5H 1TZPA 4C4NA 3N1MB 4C4MA 4MUQA 4OAKA 3K7HB 3K7IB 4JIDA 2VO9A 3N1OA 1LBUA 1U10A 3D1MA 3N1QA 4OXDA 3K7JB 3N1FA 2IBGE 3M1NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4D0Y A;  3K7G B;  3N1R A;  4NT9 A;  3N1G A;  4OX5 A;  1VHH A;  2WG4 A;  1R44 A;  2WFR A;  4F78 A;  2WG3 A;  2WFQ A;  5HNM A;  4MPH A;  4MUR A;  2WFX A;  4MUS A;  3N1P B;  3MXW A;  4OX3 A;  4MUT A;  3HO5 H;  1TZP A;  4C4N A;  3N1M B;  4C4M A;  4MUQ A;  4OAK A;  3K7H B;  3K7I B;  4JID A;  2VO9 A;  3N1O A;  1LBU A;  1U10 A;  3D1M A;  3N1Q A;  4OXD A;  3K7J B;  3N1F A;  2IBG E;  3M1N A; 
#chains in the Genus database with same CATH topology
 4D0Y A;  3K7G B;  3N1R A;  4NT9 A;  3N1G A;  2J3R A;  2J3T A;  4OX5 A;  1VHH A;  2WG4 A;  1SZ7 A;  3CUE D;  2WFR A;  3M1N A;  4F78 A;  3KXC C;  2WG3 A;  2WFQ A;  5HNM A;  4MPH A;  4MUR A;  2J3W D;  2OSO A;  2WFX A;  4MUS A;  3N1P B;  3MXW A;  3CUE B;  4OX3 A;  2CFH C;  4MUT A;  3HO5 H;  1TZP A;  4C4N A;  2OSD A;  3N1M B;  3KXC A;  3NJC A;  2J3W B;  3K7I B;  3K7H B;  4JID A;  2VO9 A;  4MUQ A;  4OAK A;  4C4M A;  2PWN A;  3N1O A;  1LBU A;  1U10 A;  3D1M A;  3N1Q A;  4OXD A;  2CFH A;  1WC8 A;  2C0J B;  2BJN A;  3K7J B;  2J3R B;  2J3T B;  3N1F A;  2IBG E;  1WC9 A;  2C0J A;  1R44 A; 
#chains in the Genus database with same CATH homology
 4D0Y A;  3K7G B;  3N1R A;  4NT9 A;  3N1G A;  4OX5 A;  1VHH A;  2WG4 A;  1R44 A;  2WFR A;  4F78 A;  2WG3 A;  2WFQ A;  5HNM A;  4MPH A;  4MUR A;  2WFX A;  4MUS A;  3N1P B;  3MXW A;  4OX3 A;  4MUT A;  3HO5 H;  1TZP A;  4C4N A;  3N1M B;  4C4M A;  4MUQ A;  4OAK A;  3K7H B;  3K7I B;  4JID A;  2VO9 A;  3N1O A;  1LBU A;  1U10 A;  3D1M A;  3N1Q A;  4OXD A;  3K7J B;  3N1F A;  2IBG E;  3M1N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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