3K7HB

Crystal structure of the e95k mutant of the indian hedgehog n-terminal signalling domain
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
157
structure length
157
Chain Sequence
PRKLVPLAYKQFSPNVPEKTLGASGRYEGKIARSSERFKELTPNYNPDIIFKDEKNTGADRLMTQRCKDRLNSLAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYGLLARLAVEAGFDWVYYESKAHVHCSVKSEHSAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
source organism Homo sapiens
publication title Crystal structure of the E95K mutant of the Indian Hedgehog N-terminal signalling domain
rcsb
molecule keywords Indian hedgehog protein
total genus 48
structure length 157
sequence length 157
ec nomenclature
pdb deposition date 2009-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01085 HH_signal Hedgehog amino-terminal signalling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1380.10 Alpha Beta 2-Layer Sandwich Muramoyl-pentapeptide Carboxypeptidase; domain 2 Muramoyl-pentapeptide Carboxypeptidase; domain 2 3k7hB00
4F78A 1U10A 2IBGE 1TZPA 4OXDA 4MUSA 4MURA 2WFQA 3D1MA 4D0YA 3N1OA 3M1NA 3N1MB 3N1FA 3MXWA 2WG4A 4JIDA 4MPHA 2WFXA 1R44A 5HNMA 2WG3A 4C4NA 1VHHA 3K7GB 4MUQA 1LBUA 4MUTA 3N1QA 4OX5A 4OX3A 4NT9A 3K7IB 3K7HB 4C4MA 3HO5H 2VO9A 3K7JB 2WFRA 4OAKA 3N1PB 3N1GA 3N1RA
chains in the Genus database with same CATH superfamily
1SZ7A 4F78A 1U10A 2IBGE 1TZPA 3KXCC 4OXDA 2J3WD 4MUSA 2CFHC 2J3RA 4MURA 2WFQA 2J3WB 3D1MA 4D0YA 3N1OA 3M1NA 3N1MB 2C0JA 3CUED 3N1FA 3KXCA 1WC9A 3CUEB 2CFHA 3MXWA 2J3TA 2PWNA 2WG4A 4JIDA 4MPHA 2BJNA 1R44A 2J3RB 2WFXA 5HNMA 2WG3A 2OSOA 4C4NA 1VHHA 3K7GB 4MUQA 2OSDA 1LBUA 4MUTA 3N1QA 4OX5A 4OX3A 4NT9A 3K7IB 2C0JB 3K7HB 4C4MA 3HO5H 2VO9A 3K7JB 2WFRA 4OAKA 2J3TB 3N1PB 3N1GA 3N1RA 1WC8A 3NJCA
chains in the Genus database with same CATH topology
4F78A 1U10A 2IBGE 1TZPA 4OXDA 4MUSA 4MURA 2WFQA 3D1MA 4D0YA 3N1OA 3M1NA 3N1MB 3N1FA 3MXWA 2WG4A 4JIDA 4MPHA 2WFXA 1R44A 5HNMA 2WG3A 4C4NA 1VHHA 3K7GB 4MUQA 1LBUA 4MUTA 3N1QA 4OX5A 4OX3A 4NT9A 3K7IB 3K7HB 4C4MA 3HO5H 2VO9A 3K7JB 2WFRA 4OAKA 3N1PB 3N1GA 3N1RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4F78 A;  1U10 A;  2IBG E;  1TZP A;  4OXD A;  4MUS A;  4MUR A;  2WFQ A;  3D1M A;  4D0Y A;  3N1O A;  3M1N A;  3N1M B;  3N1F A;  3MXW A;  2WG4 A;  4JID A;  4MPH A;  2WFX A;  1R44 A;  5HNM A;  2WG3 A;  4C4N A;  1VHH A;  3K7G B;  4MUQ A;  1LBU A;  4MUT A;  3N1Q A;  4OX5 A;  4OX3 A;  4NT9 A;  3K7I B;  3K7H B;  4C4M A;  3HO5 H;  2VO9 A;  3K7J B;  2WFR A;  4OAK A;  3N1P B;  3N1G A;  3N1R A; 
#chains in the Genus database with same CATH topology
 1SZ7 A;  4F78 A;  1U10 A;  2IBG E;  1TZP A;  3KXC C;  4OXD A;  2J3W D;  4MUS A;  2CFH C;  2J3R A;  4MUR A;  2WFQ A;  2J3W B;  3D1M A;  4D0Y A;  3N1O A;  3M1N A;  3N1M B;  2C0J A;  3CUE D;  3N1F A;  3KXC A;  1WC9 A;  3CUE B;  2CFH A;  3MXW A;  2J3T A;  2PWN A;  2WG4 A;  4JID A;  4MPH A;  2BJN A;  1R44 A;  2J3R B;  2WFX A;  5HNM A;  2WG3 A;  2OSO A;  4C4N A;  1VHH A;  3K7G B;  4MUQ A;  2OSD A;  1LBU A;  4MUT A;  3N1Q A;  4OX5 A;  4OX3 A;  4NT9 A;  3K7I B;  2C0J B;  3K7H B;  4C4M A;  3HO5 H;  2VO9 A;  3K7J B;  2WFR A;  4OAK A;  2J3T B;  3N1P B;  3N1G A;  3N1R A;  1WC8 A;  3NJC A; 
#chains in the Genus database with same CATH homology
 4F78 A;  1U10 A;  2IBG E;  1TZP A;  4OXD A;  4MUS A;  4MUR A;  2WFQ A;  3D1M A;  4D0Y A;  3N1O A;  3M1N A;  3N1M B;  3N1F A;  3MXW A;  2WG4 A;  4JID A;  4MPH A;  2WFX A;  1R44 A;  5HNM A;  2WG3 A;  4C4N A;  1VHH A;  3K7G B;  4MUQ A;  1LBU A;  4MUT A;  3N1Q A;  4OX5 A;  4OX3 A;  4NT9 A;  3K7I B;  3K7H B;  4C4M A;  3HO5 H;  2VO9 A;  3K7J B;  2WFR A;  4OAK A;  3N1P B;  3N1G A;  3N1R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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