3K7HB

Crystal structure of the e95k mutant of the indian hedgehog n-terminal signalling domain
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
157
structure length
157
Chain Sequence
PRKLVPLAYKQFSPNVPEKTLGASGRYEGKIARSSERFKELTPNYNPDIIFKDEKNTGADRLMTQRCKDRLNSLAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYGLLARLAVEAGFDWVYYESKAHVHCSVKSEHSAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the E95K mutant of the Indian Hedgehog N-terminal signalling domain
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Indian hedgehog protein
total genus 48
structure length 157
sequence length 157
ec nomenclature
pdb deposition date 2009-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01085 HH_signal Hedgehog amino-terminal signalling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1380.10 Alpha Beta 2-Layer Sandwich Muramoyl-pentapeptide Carboxypeptidase; domain 2 Muramoyl-pentapeptide Carboxypeptidase; domain 2 3k7hB00
2WG3A 4C4NA 1R44A 1TZPA 4MUQA 4MPHA 3N1FA 1LBUA 3HO5H 3D1MA 4MUTA 4D0YA 2WG4A 4OAKA 3K7JB 1U10A 1VHHA 4JIDA 2WFXA 3N1RA 4MURA 2IBGE 4NT9A 2WFRA 4MUSA 4OXDA 3K7HB 3N1MB 3N1QA 5HNMA 3MXWA 2VO9A 3K7GB 3N1PB 4OX5A 4F78A 3M1NA 3N1GA 2WFQA 4OX3A 3K7IB 4C4MA 3N1OA
chains in the Genus database with same CATH superfamily
2WG3A 2OSOA 4C4NA 1R44A 2J3WD 1TZPA 4MUQA 4MPHA 3N1FA 1LBUA 3HO5H 2J3TB 3D1MA 2J3RB 4MUTA 4D0YA 2C0JB 1WC9A 2WG4A 4OAKA 3K7JB 1U10A 1VHHA 1WC8A 3CUED 2J3WB 4JIDA 2WFXA 2PWNA 2OSDA 2IBGE 3N1RA 4MURA 4NT9A 3KXCC 2WFRA 4MUSA 4OXDA 3NJCA 1SZ7A 2J3TA 3K7HB 3N1MB 2J3RA 3KXCA 2C0JA 3N1QA 2CFHC 3MXWA 5HNMA 2VO9A 3K7GB 3CUEB 3N1PB 4OX5A 3M1NA 4F78A 3N1GA 2BJNA 2WFQA 2CFHA 4OX3A 3K7IB 4C4MA 3N1OA
chains in the Genus database with same CATH topology
2WG3A 4C4NA 1R44A 1TZPA 4MUQA 4MPHA 3N1FA 1LBUA 3HO5H 3D1MA 4MUTA 4D0YA 2WG4A 4OAKA 3K7JB 1U10A 1VHHA 4JIDA 2WFXA 3N1RA 4MURA 2IBGE 4NT9A 2WFRA 4MUSA 4OXDA 3K7HB 3N1MB 3N1QA 5HNMA 3MXWA 2VO9A 3K7GB 3N1PB 4OX5A 4F78A 3M1NA 3N1GA 2WFQA 4OX3A 3K7IB 4C4MA 3N1OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WG3 A;  4C4N A;  1R44 A;  1TZP A;  4MUQ A;  4MPH A;  3N1F A;  1LBU A;  3HO5 H;  3D1M A;  4MUT A;  4D0Y A;  2WG4 A;  4OAK A;  3K7J B;  1U10 A;  1VHH A;  4JID A;  2WFX A;  3N1R A;  4MUR A;  2IBG E;  4NT9 A;  2WFR A;  4MUS A;  4OXD A;  3K7H B;  3N1M B;  3N1Q A;  5HNM A;  3MXW A;  2VO9 A;  3K7G B;  3N1P B;  4OX5 A;  4F78 A;  3M1N A;  3N1G A;  2WFQ A;  4OX3 A;  3K7I B;  4C4M A;  3N1O A; 
#chains in the Genus database with same CATH topology
 2WG3 A;  2OSO A;  4C4N A;  1R44 A;  2J3W D;  1TZP A;  4MUQ A;  4MPH A;  3N1F A;  1LBU A;  3HO5 H;  2J3T B;  3D1M A;  2J3R B;  4MUT A;  4D0Y A;  2C0J B;  1WC9 A;  2WG4 A;  4OAK A;  3K7J B;  1U10 A;  1VHH A;  1WC8 A;  3CUE D;  2J3W B;  4JID A;  2WFX A;  2PWN A;  2OSD A;  2IBG E;  3N1R A;  4MUR A;  4NT9 A;  3KXC C;  2WFR A;  4MUS A;  4OXD A;  3NJC A;  1SZ7 A;  2J3T A;  3K7H B;  3N1M B;  2J3R A;  3KXC A;  2C0J A;  3N1Q A;  2CFH C;  3MXW A;  5HNM A;  2VO9 A;  3K7G B;  3CUE B;  3N1P B;  4OX5 A;  3M1N A;  4F78 A;  3N1G A;  2BJN A;  2WFQ A;  2CFH A;  4OX3 A;  3K7I B;  4C4M A;  3N1O A; 
#chains in the Genus database with same CATH homology
 2WG3 A;  4C4N A;  1R44 A;  1TZP A;  4MUQ A;  4MPH A;  3N1F A;  1LBU A;  3HO5 H;  3D1M A;  4MUT A;  4D0Y A;  2WG4 A;  4OAK A;  3K7J B;  1U10 A;  1VHH A;  4JID A;  2WFX A;  3N1R A;  4MUR A;  2IBG E;  4NT9 A;  2WFR A;  4MUS A;  4OXD A;  3K7H B;  3N1M B;  3N1Q A;  5HNM A;  3MXW A;  2VO9 A;  3K7G B;  3N1P B;  4OX5 A;  4F78 A;  3M1N A;  3N1G A;  2WFQ A;  4OX3 A;  3K7I B;  4C4M A;  3N1O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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