3K7IB

Crystal structure of the e131k mutant of the indian hedgehog n-terminal signalling domain
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
157
structure length
157
Chain Sequence
PRKLVPLAYKQFSPNVPEKTLGASGRYEGKIARSSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDRLNSLAISVMNQWPGVKLRVTKGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYGLLARLAVEAGFDWVYYESKAHVHCSVKSEHSAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
source organism Homo sapiens
publication title Crystal structure of the E131K mutant of the Indian Hedgehog N-terminal signalling domain
rcsb
molecule keywords Indian hedgehog protein
total genus 45
structure length 157
sequence length 157
ec nomenclature
pdb deposition date 2009-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01085 HH_signal Hedgehog amino-terminal signalling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1380.10 Alpha Beta 2-Layer Sandwich Muramoyl-pentapeptide Carboxypeptidase; domain 2 Muramoyl-pentapeptide Carboxypeptidase; domain 2 3k7iB00
4MPHA 4OAKA 1R44A 3N1GA 3N1PB 3N1FA 3N1OA 4MUSA 2VO9A 4MURA 2IBGE 4OX5A 4JIDA 2WFRA 4MUTA 3HO5H 2WFQA 3D1MA 3K7IB 3K7GB 3MXWA 3N1RA 3N1MB 3K7JB 4C4MA 1VHHA 1U10A 4NT9A 3N1QA 4OXDA 4MUQA 2WFXA 5HNMA 3K7HB 3M1NA 1LBUA 1TZPA 2WG4A 4C4NA 4F78A 4D0YA 2WG3A 4OX3A
chains in the Genus database with same CATH superfamily
2WG3A 2PWNA 4MPHA 1SZ7A 4OAKA 2C0JB 1R44A 2J3RB 3N1PB 3N1FA 3N1OA 3N1GA 4MUSA 2OSDA 2VO9A 3KXCC 4MURA 2IBGE 3CUED 3CUEB 2J3TB 4OX5A 4JIDA 2WFRA 4MUTA 2CFHC 3HO5H 2WFQA 3D1MA 3K7IB 3K7GB 3MXWA 3N1RA 3N1MB 2J3RA 2C0JA 3K7JB 4C4MA 1VHHA 1U10A 1WC9A 4NT9A 3N1QA 4OXDA 4MUQA 2BJNA 2OSOA 3NJCA 1WC8A 2WFXA 5HNMA 3KXCA 2J3TA 3K7HB 3M1NA 1LBUA 2CFHA 1TZPA 2WG4A 4C4NA 4F78A 4D0YA 2J3WD 2J3WB 4OX3A
chains in the Genus database with same CATH topology
4MPHA 4OAKA 1R44A 3N1GA 3N1PB 3N1FA 3N1OA 4MUSA 2VO9A 4MURA 2IBGE 4OX5A 4JIDA 2WFRA 4MUTA 3HO5H 2WFQA 3D1MA 3K7IB 3K7GB 3MXWA 3N1RA 3N1MB 3K7JB 4C4MA 1VHHA 1U10A 4NT9A 3N1QA 4OXDA 4MUQA 2WFXA 5HNMA 3K7HB 3M1NA 1LBUA 1TZPA 2WG4A 4C4NA 4F78A 4D0YA 2WG3A 4OX3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MPH A;  4OAK A;  1R44 A;  3N1G A;  3N1P B;  3N1F A;  3N1O A;  4MUS A;  2VO9 A;  4MUR A;  2IBG E;  4OX5 A;  4JID A;  2WFR A;  4MUT A;  3HO5 H;  2WFQ A;  3D1M A;  3K7I B;  3K7G B;  3MXW A;  3N1R A;  3N1M B;  3K7J B;  4C4M A;  1VHH A;  1U10 A;  4NT9 A;  3N1Q A;  4OXD A;  4MUQ A;  2WFX A;  5HNM A;  3K7H B;  3M1N A;  1LBU A;  1TZP A;  2WG4 A;  4C4N A;  4F78 A;  4D0Y A;  2WG3 A;  4OX3 A; 
#chains in the Genus database with same CATH topology
 2WG3 A;  2PWN A;  4MPH A;  1SZ7 A;  4OAK A;  2C0J B;  1R44 A;  2J3R B;  3N1P B;  3N1F A;  3N1O A;  3N1G A;  4MUS A;  2OSD A;  2VO9 A;  3KXC C;  4MUR A;  2IBG E;  3CUE D;  3CUE B;  2J3T B;  4OX5 A;  4JID A;  2WFR A;  4MUT A;  2CFH C;  3HO5 H;  2WFQ A;  3D1M A;  3K7I B;  3K7G B;  3MXW A;  3N1R A;  3N1M B;  2J3R A;  2C0J A;  3K7J B;  4C4M A;  1VHH A;  1U10 A;  1WC9 A;  4NT9 A;  3N1Q A;  4OXD A;  4MUQ A;  2BJN A;  2OSO A;  3NJC A;  1WC8 A;  2WFX A;  5HNM A;  3KXC A;  2J3T A;  3K7H B;  3M1N A;  1LBU A;  2CFH A;  1TZP A;  2WG4 A;  4C4N A;  4F78 A;  4D0Y A;  2J3W D;  2J3W B;  4OX3 A; 
#chains in the Genus database with same CATH homology
 4MPH A;  4OAK A;  1R44 A;  3N1G A;  3N1P B;  3N1F A;  3N1O A;  4MUS A;  2VO9 A;  4MUR A;  2IBG E;  4OX5 A;  4JID A;  2WFR A;  4MUT A;  3HO5 H;  2WFQ A;  3D1M A;  3K7I B;  3K7G B;  3MXW A;  3N1R A;  3N1M B;  3K7J B;  4C4M A;  1VHH A;  1U10 A;  4NT9 A;  3N1Q A;  4OXD A;  4MUQ A;  2WFX A;  5HNM A;  3K7H B;  3M1N A;  1LBU A;  1TZP A;  2WG4 A;  4C4N A;  4F78 A;  4D0Y A;  2WG3 A;  4OX3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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