3K7IB

Crystal structure of the e131k mutant of the indian hedgehog n-terminal signalling domain
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
157
structure length
157
Chain Sequence
PRKLVPLAYKQFSPNVPEKTLGASGRYEGKIARSSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDRLNSLAISVMNQWPGVKLRVTKGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYGLLARLAVEAGFDWVYYESKAHVHCSVKSEHSAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the E131K mutant of the Indian Hedgehog N-terminal signalling domain
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Indian hedgehog protein
total genus 45
structure length 157
sequence length 157
ec nomenclature
pdb deposition date 2009-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01085 HH_signal Hedgehog amino-terminal signalling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1380.10 Alpha Beta 2-Layer Sandwich Muramoyl-pentapeptide Carboxypeptidase; domain 2 Muramoyl-pentapeptide Carboxypeptidase; domain 2 3k7iB00
4NT9A 4MUQA 2WFRA 3N1MB 1TZPA 3K7IB 3K7JB 4MUTA 4MURA 1VHHA 3HO5H 4F78A 4C4NA 1U10A 2WFQA 2WG3A 3M1NA 4OX3A 3N1RA 3N1OA 4OX5A 3N1QA 2VO9A 4JIDA 4OXDA 3D1MA 4C4MA 2WFXA 1R44A 2IBGE 3K7HB 1LBUA 3N1GA 4MUSA 4D0YA 3MXWA 5HNMA 4OAKA 3N1PB 2WG4A 3N1FA 3K7GB 4MPHA
chains in the Genus database with same CATH superfamily
4NT9A 3KXCA 2J3TA 2J3WB 1WC8A 2C0JA 4MUQA 2OSOA 2WFRA 3N1MB 1TZPA 3NJCA 3K7JB 3K7IB 4C4NA 2J3RA 4MUTA 4MURA 1VHHA 1WC9A 2OSDA 3CUED 3HO5H 1U10A 2WFQA 2WG3A 3M1NA 4OX3A 3K7GB 3N1OA 3N1RA 1SZ7A 4OX5A 2BJNA 3N1QA 2CFHC 2J3TB 2VO9A 4JIDA 2C0JB 3D1MA 4OXDA 2J3WD 3CUEB 2CFHA 4C4MA 4F78A 2PWNA 1R44A 2IBGE 2WFXA 2J3RB 3K7HB 3N1GA 3KXCC 4MUSA 4D0YA 3MXWA 5HNMA 4OAKA 3N1PB 2WG4A 3N1FA 1LBUA 4MPHA
chains in the Genus database with same CATH topology
4NT9A 4MUQA 2WFRA 3N1MB 1TZPA 3K7IB 3K7JB 4MUTA 4MURA 1VHHA 3HO5H 4F78A 4C4NA 1U10A 2WFQA 2WG3A 3M1NA 4OX3A 3N1RA 3N1OA 4OX5A 3N1QA 2VO9A 4JIDA 4OXDA 3D1MA 4C4MA 2WFXA 1R44A 2IBGE 3K7HB 1LBUA 3N1GA 4MUSA 4D0YA 3MXWA 5HNMA 4OAKA 3N1PB 2WG4A 3N1FA 3K7GB 4MPHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NT9 A;  4MUQ A;  2WFR A;  3N1M B;  1TZP A;  3K7I B;  3K7J B;  4MUT A;  4MUR A;  1VHH A;  3HO5 H;  4F78 A;  4C4N A;  1U10 A;  2WFQ A;  2WG3 A;  3M1N A;  4OX3 A;  3N1R A;  3N1O A;  4OX5 A;  3N1Q A;  2VO9 A;  4JID A;  4OXD A;  3D1M A;  4C4M A;  2WFX A;  1R44 A;  2IBG E;  3K7H B;  1LBU A;  3N1G A;  4MUS A;  4D0Y A;  3MXW A;  5HNM A;  4OAK A;  3N1P B;  2WG4 A;  3N1F A;  3K7G B;  4MPH A; 
#chains in the Genus database with same CATH topology
 4NT9 A;  3KXC A;  2J3T A;  2J3W B;  1WC8 A;  2C0J A;  4MUQ A;  2OSO A;  2WFR A;  3N1M B;  1TZP A;  3NJC A;  3K7J B;  3K7I B;  4C4N A;  2J3R A;  4MUT A;  4MUR A;  1VHH A;  1WC9 A;  2OSD A;  3CUE D;  3HO5 H;  1U10 A;  2WFQ A;  2WG3 A;  3M1N A;  4OX3 A;  3K7G B;  3N1O A;  3N1R A;  1SZ7 A;  4OX5 A;  2BJN A;  3N1Q A;  2CFH C;  2J3T B;  2VO9 A;  4JID A;  2C0J B;  3D1M A;  4OXD A;  2J3W D;  3CUE B;  2CFH A;  4C4M A;  4F78 A;  2PWN A;  1R44 A;  2IBG E;  2WFX A;  2J3R B;  3K7H B;  3N1G A;  3KXC C;  4MUS A;  4D0Y A;  3MXW A;  5HNM A;  4OAK A;  3N1P B;  2WG4 A;  3N1F A;  1LBU A;  4MPH A; 
#chains in the Genus database with same CATH homology
 4NT9 A;  4MUQ A;  2WFR A;  3N1M B;  1TZP A;  3K7I B;  3K7J B;  4MUT A;  4MUR A;  1VHH A;  3HO5 H;  4F78 A;  4C4N A;  1U10 A;  2WFQ A;  2WG3 A;  3M1N A;  4OX3 A;  3N1R A;  3N1O A;  4OX5 A;  3N1Q A;  2VO9 A;  4JID A;  4OXD A;  3D1M A;  4C4M A;  2WFX A;  1R44 A;  2IBG E;  3K7H B;  1LBU A;  3N1G A;  4MUS A;  4D0Y A;  3MXW A;  5HNM A;  4OAK A;  3N1P B;  2WG4 A;  3N1F A;  3K7G B;  4MPH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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