3K7JB

Crystal structure of the d100e mutant of the indian hedgehog n-terminal signalling domain
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
152
structure length
146
Chain Sequence
PRKLVPLAYKQFSPNVPEKTLGASGRYEGKIARSSERFKELTPNYNPDIIFKAERLMTQRCKDRLNSLAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYGLLARLAVEAGFDWVYYESKAHVHCSVKS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the D100E mutant of the Indian Hedgehog N-terminal signalling domain
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Indian hedgehog protein
total genus 43
structure length 146
sequence length 152
ec nomenclature
pdb deposition date 2009-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01085 HH_signal Hedgehog amino-terminal signalling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1380.10 Alpha Beta 2-Layer Sandwich Muramoyl-pentapeptide Carboxypeptidase; domain 2 Muramoyl-pentapeptide Carboxypeptidase; domain 2 3k7jB00
2VO9A 1U10A 2WFQA 4MURA 4MUSA 2WG4A 3N1OA 4C4NA 4OX5A 3MXWA 4D0YA 3HO5H 5HNMA 4OAKA 3K7GB 2WG3A 1R44A 3N1PB 4MPHA 2WFXA 2IBGE 4NT9A 4F78A 4OXDA 3K7IB 1LBUA 3K7JB 3M1NA 3N1QA 3N1RA 3N1FA 3K7HB 4MUTA 1VHHA 4MUQA 4JIDA 3D1MA 4OX3A 3N1GA 1TZPA 2WFRA 3N1MB 4C4MA
chains in the Genus database with same CATH superfamily
2VO9A 1U10A 2WFQA 2BJNA 4MURA 4MUSA 2WG4A 3N1OA 4C4NA 3CUED 4OX5A 2WFRA 2PWNA 3MXWA 4D0YA 2J3WB 2J3RA 2J3TA 3HO5H 5HNMA 4OAKA 2J3RB 2J3WD 2J3TB 3KXCA 3K7GB 4C4MA 2C0JA 2CFHC 2WG3A 1R44A 3N1PB 4MPHA 2WFXA 2C0JB 2IBGE 4NT9A 2OSDA 4F78A 4OXDA 3K7IB 1LBUA 3K7JB 3M1NA 3N1QA 3N1RA 3N1FA 3NJCA 1WC8A 3K7HB 4MUTA 2CFHA 1VHHA 4MUQA 4JIDA 3D1MA 4OX3A 3N1GA 3KXCC 1WC9A 1TZPA 2OSOA 3N1MB 1SZ7A 3CUEB
chains in the Genus database with same CATH topology
2VO9A 1U10A 2WFQA 4MURA 4MUSA 2WG4A 3N1OA 4C4NA 4OX5A 3MXWA 4D0YA 3HO5H 5HNMA 4OAKA 3K7GB 2WG3A 1R44A 3N1PB 4MPHA 2WFXA 2IBGE 4NT9A 4F78A 4OXDA 3K7IB 1LBUA 3K7JB 3M1NA 3N1QA 3N1RA 3N1FA 3K7HB 4MUTA 1VHHA 4MUQA 4JIDA 3D1MA 4OX3A 3N1GA 1TZPA 2WFRA 3N1MB 4C4MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VO9 A;  1U10 A;  2WFQ A;  4MUR A;  4MUS A;  2WG4 A;  3N1O A;  4C4N A;  4OX5 A;  3MXW A;  4D0Y A;  3HO5 H;  5HNM A;  4OAK A;  3K7G B;  2WG3 A;  1R44 A;  3N1P B;  4MPH A;  2WFX A;  2IBG E;  4NT9 A;  4F78 A;  4OXD A;  3K7I B;  1LBU A;  3K7J B;  3M1N A;  3N1Q A;  3N1R A;  3N1F A;  3K7H B;  4MUT A;  1VHH A;  4MUQ A;  4JID A;  3D1M A;  4OX3 A;  3N1G A;  1TZP A;  2WFR A;  3N1M B;  4C4M A; 
#chains in the Genus database with same CATH topology
 2VO9 A;  1U10 A;  2WFQ A;  2BJN A;  4MUR A;  4MUS A;  2WG4 A;  3N1O A;  4C4N A;  3CUE D;  4OX5 A;  2WFR A;  2PWN A;  3MXW A;  4D0Y A;  2J3W B;  2J3R A;  2J3T A;  3HO5 H;  5HNM A;  4OAK A;  2J3R B;  2J3W D;  2J3T B;  3KXC A;  3K7G B;  4C4M A;  2C0J A;  2CFH C;  2WG3 A;  1R44 A;  3N1P B;  4MPH A;  2WFX A;  2C0J B;  2IBG E;  4NT9 A;  2OSD A;  4F78 A;  4OXD A;  3K7I B;  1LBU A;  3K7J B;  3M1N A;  3N1Q A;  3N1R A;  3N1F A;  3NJC A;  1WC8 A;  3K7H B;  4MUT A;  2CFH A;  1VHH A;  4MUQ A;  4JID A;  3D1M A;  4OX3 A;  3N1G A;  3KXC C;  1WC9 A;  1TZP A;  2OSO A;  3N1M B;  1SZ7 A;  3CUE B; 
#chains in the Genus database with same CATH homology
 2VO9 A;  1U10 A;  2WFQ A;  4MUR A;  4MUS A;  2WG4 A;  3N1O A;  4C4N A;  4OX5 A;  3MXW A;  4D0Y A;  3HO5 H;  5HNM A;  4OAK A;  3K7G B;  2WG3 A;  1R44 A;  3N1P B;  4MPH A;  2WFX A;  2IBG E;  4NT9 A;  4F78 A;  4OXD A;  3K7I B;  1LBU A;  3K7J B;  3M1N A;  3N1Q A;  3N1R A;  3N1F A;  3K7H B;  4MUT A;  1VHH A;  4MUQ A;  4JID A;  3D1M A;  4OX3 A;  3N1G A;  1TZP A;  2WFR A;  3N1M B;  4C4M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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