3M1NA

Crystal structure of human sonic hedgehog n-terminal domain
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
164
structure length
164
Chain Sequence
GPGRGFGKRRHPKKLTPLAYKQFIPNVAEKTLGASGRYEGKISRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHCSVKAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mapping sonic hedgehog-receptor interactions by steric interference.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Sonic hedgehog protein
total genus 40
structure length 164
sequence length 164
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-03-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01085 HH_signal Hedgehog amino-terminal signalling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1380.10 Alpha Beta 2-Layer Sandwich Muramoyl-pentapeptide Carboxypeptidase; domain 2 Muramoyl-pentapeptide Carboxypeptidase; domain 2 3m1nA01
3N1FA 3N1PB 3N1GA 2WG3A 4MUTA 5HNMA 3N1MB 4OXDA 2WFQA 2WG4A 3HO5H 4D0YA 4MPHA 1TZPA 4OX5A 1LBUA 2WFRA 1VHHA 4NT9A 3M1NA 2IBGE 3N1QA 3N1OA 4C4MA 3N1RA 2VO9A 3MXWA 4OX3A 1R44A 4MUSA 4F78A 3K7HB 3K7JB 3K7GB 1U10A 4MURA 3D1MA 4JIDA 4MUQA 4OAKA 4C4NA 3K7IB 2WFXA
chains in the Genus database with same CATH superfamily
3N1FA 3N1PB 3N1GA 2J3WB 2WG3A 4MUTA 5HNMA 2C0JB 3N1MB 4OXDA 3CUED 3NJCA 2C0JA 3KXCA 2WFQA 2WG4A 3HO5H 2OSOA 4D0YA 2J3RB 1TZPA 2CFHC 1LBUA 2J3TB 2OSDA 2WFRA 4MPHA 4OX5A 1VHHA 2J3RA 2J3TA 4NT9A 3M1NA 2IBGE 2J3WD 3N1QA 2BJNA 3N1OA 4C4MA 3N1RA 1SZ7A 2VO9A 3CUEB 1WC8A 3KXCC 3MXWA 4OX3A 1R44A 4MUSA 4F78A 1WC9A 3K7HB 3K7JB 2PWNA 3K7GB 1U10A 4MURA 3D1MA 4JIDA 4MUQA 4OAKA 4C4NA 2CFHA 3K7IB 2WFXA
chains in the Genus database with same CATH topology
3N1FA 3N1PB 3N1GA 2WG3A 4MUTA 5HNMA 3N1MB 4OXDA 2WFQA 2WG4A 3HO5H 4D0YA 4MPHA 1TZPA 4OX5A 1LBUA 2WFRA 1VHHA 4NT9A 3M1NA 2IBGE 3N1QA 3N1OA 4C4MA 3N1RA 2VO9A 3MXWA 4OX3A 1R44A 4MUSA 4F78A 3K7HB 3K7JB 3K7GB 1U10A 4MURA 3D1MA 4JIDA 4MUQA 4OAKA 4C4NA 3K7IB 2WFXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3N1F A;  3N1P B;  3N1G A;  2WG3 A;  4MUT A;  5HNM A;  3N1M B;  4OXD A;  2WFQ A;  2WG4 A;  3HO5 H;  4D0Y A;  4MPH A;  1TZP A;  4OX5 A;  1LBU A;  2WFR A;  1VHH A;  4NT9 A;  3M1N A;  2IBG E;  3N1Q A;  3N1O A;  4C4M A;  3N1R A;  2VO9 A;  3MXW A;  4OX3 A;  1R44 A;  4MUS A;  4F78 A;  3K7H B;  3K7J B;  3K7G B;  1U10 A;  4MUR A;  3D1M A;  4JID A;  4MUQ A;  4OAK A;  4C4N A;  3K7I B;  2WFX A; 
#chains in the Genus database with same CATH topology
 3N1F A;  3N1P B;  3N1G A;  2J3W B;  2WG3 A;  4MUT A;  5HNM A;  2C0J B;  3N1M B;  4OXD A;  3CUE D;  3NJC A;  2C0J A;  3KXC A;  2WFQ A;  2WG4 A;  3HO5 H;  2OSO A;  4D0Y A;  2J3R B;  1TZP A;  2CFH C;  1LBU A;  2J3T B;  2OSD A;  2WFR A;  4MPH A;  4OX5 A;  1VHH A;  2J3R A;  2J3T A;  4NT9 A;  3M1N A;  2IBG E;  2J3W D;  3N1Q A;  2BJN A;  3N1O A;  4C4M A;  3N1R A;  1SZ7 A;  2VO9 A;  3CUE B;  1WC8 A;  3KXC C;  3MXW A;  4OX3 A;  1R44 A;  4MUS A;  4F78 A;  1WC9 A;  3K7H B;  3K7J B;  2PWN A;  3K7G B;  1U10 A;  4MUR A;  3D1M A;  4JID A;  4MUQ A;  4OAK A;  4C4N A;  2CFH A;  3K7I B;  2WFX A; 
#chains in the Genus database with same CATH homology
 3N1F A;  3N1P B;  3N1G A;  2WG3 A;  4MUT A;  5HNM A;  3N1M B;  4OXD A;  2WFQ A;  2WG4 A;  3HO5 H;  4D0Y A;  4MPH A;  1TZP A;  4OX5 A;  1LBU A;  2WFR A;  1VHH A;  4NT9 A;  3M1N A;  2IBG E;  3N1Q A;  3N1O A;  4C4M A;  3N1R A;  2VO9 A;  3MXW A;  4OX3 A;  1R44 A;  4MUS A;  4F78 A;  3K7H B;  3K7J B;  3K7G B;  1U10 A;  4MUR A;  3D1M A;  4JID A;  4MUQ A;  4OAK A;  4C4N A;  3K7I B;  2WFX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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