3M1NA

Crystal structure of human sonic hedgehog n-terminal domain
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
164
structure length
164
Chain Sequence
GPGRGFGKRRHPKKLTPLAYKQFIPNVAEKTLGASGRYEGKISRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHCSVKAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mapping sonic hedgehog-receptor interactions by steric interference.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Sonic hedgehog protein
total genus 40
structure length 164
sequence length 164
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-03-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01085 HH_signal Hedgehog amino-terminal signalling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1380.10 Alpha Beta 2-Layer Sandwich Muramoyl-pentapeptide Carboxypeptidase; domain 2 Muramoyl-pentapeptide Carboxypeptidase; domain 2 3m1nA01
3M1NA 3K7IB 4MUTA 4OX3A 3D1MA 1LBUA 3K7HB 2WG4A 2WFQA 3HO5H 4MPHA 2IBGE 4MUQA 3N1QA 4JIDA 4NT9A 4C4MA 2WFXA 4C4NA 4OX5A 4MURA 2WFRA 2WG3A 1TZPA 3N1OA 3N1MB 3N1FA 4OAKA 1R44A 5HNMA 3K7JB 3N1GA 3N1PB 1U10A 2VO9A 3K7GB 3N1RA 4D0YA 4F78A 3MXWA 4MUSA 4OXDA 1VHHA
chains in the Genus database with same CATH superfamily
3M1NA 3K7IB 4MUTA 4OX3A 2CFHC 1LBUA 2BJNA 3D1MA 3K7HB 2WG4A 2WFQA 3HO5H 4MPHA 2IBGE 4MUQA 2J3WD 2J3WB 3N1QA 4JIDA 1SZ7A 4NT9A 4C4MA 1WC8A 2WFXA 4C4NA 2C0JA 2J3RA 4MURA 2WFRA 2WG3A 1TZPA 3N1OA 3N1MB 3N1FA 3NJCA 1R44A 2OSDA 4OAKA 5HNMA 3K7JB 3N1GA 2J3TA 3N1PB 1U10A 1WC9A 2J3TB 2VO9A 4OX5A 2PWNA 3K7GB 3N1RA 3KXCA 4D0YA 4F78A 2J3RB 3KXCC 2C0JB 3CUED 3CUEB 3MXWA 4MUSA 2OSOA 4OXDA 2CFHA 1VHHA
chains in the Genus database with same CATH topology
3M1NA 3K7IB 4MUTA 4OX3A 3D1MA 1LBUA 3K7HB 2WG4A 2WFQA 3HO5H 4MPHA 2IBGE 4MUQA 3N1QA 4JIDA 4NT9A 4C4MA 2WFXA 4C4NA 4OX5A 4MURA 2WFRA 2WG3A 1TZPA 3N1OA 3N1MB 3N1FA 4OAKA 1R44A 5HNMA 3K7JB 3N1GA 3N1PB 1U10A 2VO9A 3K7GB 3N1RA 4D0YA 4F78A 3MXWA 4MUSA 4OXDA 1VHHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M1N A;  3K7I B;  4MUT A;  4OX3 A;  3D1M A;  1LBU A;  3K7H B;  2WG4 A;  2WFQ A;  3HO5 H;  4MPH A;  2IBG E;  4MUQ A;  3N1Q A;  4JID A;  4NT9 A;  4C4M A;  2WFX A;  4C4N A;  4OX5 A;  4MUR A;  2WFR A;  2WG3 A;  1TZP A;  3N1O A;  3N1M B;  3N1F A;  4OAK A;  1R44 A;  5HNM A;  3K7J B;  3N1G A;  3N1P B;  1U10 A;  2VO9 A;  3K7G B;  3N1R A;  4D0Y A;  4F78 A;  3MXW A;  4MUS A;  4OXD A;  1VHH A; 
#chains in the Genus database with same CATH topology
 3M1N A;  3K7I B;  4MUT A;  4OX3 A;  2CFH C;  1LBU A;  2BJN A;  3D1M A;  3K7H B;  2WG4 A;  2WFQ A;  3HO5 H;  4MPH A;  2IBG E;  4MUQ A;  2J3W D;  2J3W B;  3N1Q A;  4JID A;  1SZ7 A;  4NT9 A;  4C4M A;  1WC8 A;  2WFX A;  4C4N A;  2C0J A;  2J3R A;  4MUR A;  2WFR A;  2WG3 A;  1TZP A;  3N1O A;  3N1M B;  3N1F A;  3NJC A;  1R44 A;  2OSD A;  4OAK A;  5HNM A;  3K7J B;  3N1G A;  2J3T A;  3N1P B;  1U10 A;  1WC9 A;  2J3T B;  2VO9 A;  4OX5 A;  2PWN A;  3K7G B;  3N1R A;  3KXC A;  4D0Y A;  4F78 A;  2J3R B;  3KXC C;  2C0J B;  3CUE D;  3CUE B;  3MXW A;  4MUS A;  2OSO A;  4OXD A;  2CFH A;  1VHH A; 
#chains in the Genus database with same CATH homology
 3M1N A;  3K7I B;  4MUT A;  4OX3 A;  3D1M A;  1LBU A;  3K7H B;  2WG4 A;  2WFQ A;  3HO5 H;  4MPH A;  2IBG E;  4MUQ A;  3N1Q A;  4JID A;  4NT9 A;  4C4M A;  2WFX A;  4C4N A;  4OX5 A;  4MUR A;  2WFR A;  2WG3 A;  1TZP A;  3N1O A;  3N1M B;  3N1F A;  4OAK A;  1R44 A;  5HNM A;  3K7J B;  3N1G A;  3N1P B;  1U10 A;  2VO9 A;  3K7G B;  3N1R A;  4D0Y A;  4F78 A;  3MXW A;  4MUS A;  4OXD A;  1VHH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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