3CC4R

Co-crystal structure of anisomycin bound to the 50s ribosomal subunit
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 39
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2008-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 3cc4R00
1Q81S 4WFAP 1QVFQ 5DM7P 3J7ZS 5JVHP 1KC8S 5GAET 4WFBP 2QEXR 3PIPP 1Q7YS 2ZJQP 4WF9P 4V19W 5HL7P 1K8AS 3CC7R 4U67P 2QA4R 3CMAR 3G6ER 1I4JA 1W2BQ 5GAHT 1VQNR 1NJIS 1YI2R 1VQ5R 3CCUR 3CCVR 1VQ4R 1VQ9R 1VQ7R 3CCRR 1KD1S 1YJ9R 1VQLR 2ZJRP 3I55R 4WCEP 3PIOP 3CCSR 3CCER 3G4SR 1VQ6R 3CPWQ 3CC2R 5GADT 1K73S 3G71R 2ZJPP 1M90S 1K9MS 1M1KS 2OTLR 3CD6R 1VQOR 1VQPR 1KQSQ 1YJNR 3CF5P 1JJ2Q 1Q82S 3DLLP 3CCJR 3CCQR 1YHQR 4UY8S 1YJWR 1Q86S 1VQKR 1YIJR 1VQMR 3OW2Q 5GAGT 4IOCP 5JVGP 3CC4R 3J7YT 1N8RS 4IO9P 1BXEA 5MLCU 3CCLR 2OTJR 5DM6P 3CXCQ 4IOAP 1VQ8R 3CMER 4WFNP 1QVGQ 1YITR 1S72R 3CCMR 3I56R 5H1SU
chains in the Genus database with same CATH superfamily
1Q81S 4WFAP 1QVFQ 2D0OA 5DM7P 3J7ZS 5JVHP 1KC8S 5GAET 1F80A 4WFBP 2QEXR 3PIPP 2C43A 3NFDA 2ZJQP 1Q7YS 2JBZA 4WF9P 4V19W 5HL7P 1K8AS 3CC7R 2WASB 1FTHA 4U67P 2QA4R 3CMAR 3NE9A 3G6ER 1I4JA 1W2BQ 1NBWA 5GAHT 1VQNR 1NJIS 1YI2R 2D0PA 1VQ5R 2WDYA 3CCUR 1FTFA 3CCVR 1F7TA 1VQ4R 1VQ9R 1VQ7R 2JCAA 3CCRR 1KD1S 1YJ9R 2WDOA 2WDSA 3QMNA 1VQLR 4DXEA 2ZJRP 3NE3B 3I55R 3GWMA 4WCEP 3HYKA 3PIOP 3CCSR 3CCER 3G4SR 1VQ6R 3CPWQ 3CC2R 5GADT 2WATA 1K73S 3G71R 2ZJPP 1QR0A 2CG5A 4MRTA 1K9MS 1M90S 3NE1A 1M1KS 4JM7A 2OTLR 5CMOA 3CD6R 1VQOR 1VQPR 4HC6A 1KQSQ 1YJNR 3CF5P 1JJ2Q 1Q82S 2QG8A 3CCJR 3DLLP 3CCQR 1YHQR 4UY8S 1YJWR 1Q86S 2BYDA 2BDDA 1VQKR 1YIJR 1VQMR 3OW2Q 5GAGT 4IOCP 5JVGP 3CC4R 3J7YT 1N8RS 4IO9P 1BXEA 5MLCU 1FTEA 3CCLR 2WASA 2OTJR 5CXDA 5DM6P 3CXCQ 3HQJA 4IOAP 1VQ8R 3CMER 1F7LA 4WFNP 1QVGQ 1YITR 3H7QA 1S72R 3CCMR 3I56R 5H1SU
chains in the Genus database with same CATH topology
1Q81S 4WFAP 1QVFQ 5DM7P 3J7ZS 5JVHP 1KC8S 5GAET 4WFBP 2QEXR 3PIPP 1Q7YS 2ZJQP 4WF9P 4V19W 5HL7P 1K8AS 3CC7R 4U67P 2QA4R 3CMAR 3G6ER 1I4JA 1W2BQ 5GAHT 1VQNR 1NJIS 1YI2R 1VQ5R 3CCUR 3CCVR 1VQ4R 1VQ9R 1VQ7R 3CCRR 1KD1S 1YJ9R 1VQLR 2ZJRP 3I55R 4WCEP 3PIOP 3CCSR 3CCER 3G4SR 1VQ6R 3CPWQ 3CC2R 5GADT 1K73S 3G71R 2ZJPP 1M90S 1K9MS 1M1KS 2OTLR 3CD6R 1VQOR 1VQPR 1KQSQ 1YJNR 3CF5P 1JJ2Q 1Q82S 3DLLP 3CCJR 3CCQR 1YHQR 4UY8S 1YJWR 1Q86S 1VQKR 1YIJR 1VQMR 3OW2Q 5GAGT 4IOCP 5JVGP 3CC4R 3J7YT 1N8RS 4IO9P 1BXEA 5MLCU 3CCLR 2OTJR 5DM6P 3CXCQ 4IOAP 1VQ8R 3CMER 4WFNP 1QVGQ 1YITR 1S72R 3CCMR 3I56R 5H1SU
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Q81 S;  4WFA P;  1QVF Q;  5DM7 P;  3J7Z S;  5JVH P;  1KC8 S;  5GAE T;  4WFB P;  2QEX R;  3PIP P;  1Q7Y S;  2ZJQ P;  4WF9 P;  4V19 W;  5HL7 P;  1K8A S;  3CC7 R;  4U67 P;  2QA4 R;  3CMA R;  3G6E R;  1I4J A;  1W2B Q;  5GAH T;  1VQN R;  1NJI S;  1YI2 R;  1VQ5 R;  3CCU R;  3CCV R;  1VQ4 R;  1VQ9 R;  1VQ7 R;  3CCR R;  1KD1 S;  1YJ9 R;  1VQL R;  2ZJR P;  3I55 R;  4WCE P;  3PIO P;  3CCS R;  3CCE R;  3G4S R;  1VQ6 R;  3CPW Q;  3CC2 R;  5GAD T;  1K73 S;  3G71 R;  2ZJP P;  1M90 S;  1K9M S;  1M1K S;  2OTL R;  3CD6 R;  1VQO R;  1VQP R;  1KQS Q;  1YJN R;  3CF5 P;  1JJ2 Q;  1Q82 S;  3DLL P;  3CCJ R;  3CCQ R;  1YHQ R;  4UY8 S;  1YJW R;  1Q86 S;  1VQK R;  1YIJ R;  1VQM R;  3OW2 Q;  5GAG T;  4IOC P;  5JVG P;  3CC4 R;  3J7Y T;  1N8R S;  4IO9 P;  1BXE A;  5MLC U;  3CCL R;  2OTJ R;  5DM6 P;  3CXC Q;  4IOA P;  1VQ8 R;  3CME R;  4WFN P;  1QVG Q;  1YIT R;  1S72 R;  3CCM R;  3I56 R;  5H1S U; 
#chains in the Genus database with same CATH topology
 1Q81 S;  4WFA P;  1QVF Q;  2D0O A;  5DM7 P;  3J7Z S;  5JVH P;  1KC8 S;  5GAE T;  1F80 A;  4WFB P;  2QEX R;  3PIP P;  2C43 A;  3NFD A;  2ZJQ P;  1Q7Y S;  2JBZ A;  4WF9 P;  4V19 W;  5HL7 P;  1K8A S;  3CC7 R;  2WAS B;  1FTH A;  4U67 P;  2QA4 R;  3CMA R;  3NE9 A;  3G6E R;  1I4J A;  1W2B Q;  1NBW A;  5GAH T;  1VQN R;  1NJI S;  1YI2 R;  2D0P A;  1VQ5 R;  2WDY A;  3CCU R;  1FTF A;  3CCV R;  1F7T A;  1VQ4 R;  1VQ9 R;  1VQ7 R;  2JCA A;  3CCR R;  1KD1 S;  1YJ9 R;  2WDO A;  2WDS A;  3QMN A;  1VQL R;  4DXE A;  2ZJR P;  3NE3 B;  3I55 R;  3GWM A;  4WCE P;  3HYK A;  3PIO P;  3CCS R;  3CCE R;  3G4S R;  1VQ6 R;  3CPW Q;  3CC2 R;  5GAD T;  2WAT A;  1K73 S;  3G71 R;  2ZJP P;  1QR0 A;  2CG5 A;  4MRT A;  1K9M S;  1M90 S;  3NE1 A;  1M1K S;  4JM7 A;  2OTL R;  5CMO A;  3CD6 R;  1VQO R;  1VQP R;  4HC6 A;  1KQS Q;  1YJN R;  3CF5 P;  1JJ2 Q;  1Q82 S;  2QG8 A;  3CCJ R;  3DLL P;  3CCQ R;  1YHQ R;  4UY8 S;  1YJW R;  1Q86 S;  2BYD A;  2BDD A;  1VQK R;  1YIJ R;  1VQM R;  3OW2 Q;  5GAG T;  4IOC P;  5JVG P;  3CC4 R;  3J7Y T;  1N8R S;  4IO9 P;  1BXE A;  5MLC U;  1FTE A;  3CCL R;  2WAS A;  2OTJ R;  5CXD A;  5DM6 P;  3CXC Q;  3HQJ A;  4IOA P;  1VQ8 R;  3CME R;  1F7L A;  4WFN P;  1QVG Q;  1YIT R;  3H7Q A;  1S72 R;  3CCM R;  3I56 R;  5H1S U; 
#chains in the Genus database with same CATH homology
 1Q81 S;  4WFA P;  1QVF Q;  5DM7 P;  3J7Z S;  5JVH P;  1KC8 S;  5GAE T;  4WFB P;  2QEX R;  3PIP P;  1Q7Y S;  2ZJQ P;  4WF9 P;  4V19 W;  5HL7 P;  1K8A S;  3CC7 R;  4U67 P;  2QA4 R;  3CMA R;  3G6E R;  1I4J A;  1W2B Q;  5GAH T;  1VQN R;  1NJI S;  1YI2 R;  1VQ5 R;  3CCU R;  3CCV R;  1VQ4 R;  1VQ9 R;  1VQ7 R;  3CCR R;  1KD1 S;  1YJ9 R;  1VQL R;  2ZJR P;  3I55 R;  4WCE P;  3PIO P;  3CCS R;  3CCE R;  3G4S R;  1VQ6 R;  3CPW Q;  3CC2 R;  5GAD T;  1K73 S;  3G71 R;  2ZJP P;  1M90 S;  1K9M S;  1M1K S;  2OTL R;  3CD6 R;  1VQO R;  1VQP R;  1KQS Q;  1YJN R;  3CF5 P;  1JJ2 Q;  1Q82 S;  3DLL P;  3CCJ R;  3CCQ R;  1YHQ R;  4UY8 S;  1YJW R;  1Q86 S;  1VQK R;  1YIJ R;  1VQM R;  3OW2 Q;  5GAG T;  4IOC P;  5JVG P;  3CC4 R;  3J7Y T;  1N8R S;  4IO9 P;  1BXE A;  5MLC U;  3CCL R;  2OTJ R;  5DM6 P;  3CXC Q;  4IOA P;  1VQ8 R;  3CME R;  4WFN P;  1QVG Q;  1YIT R;  1S72 R;  3CCM R;  3I56 R;  5H1S U; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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