3CC7R

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation c2487u
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 39
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2008-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 3cc7R00
3G4SR 4IOAP 3CCJR 1YJ9R 2OTLR 2OTJR 4WF9P 1N8RS 1S72R 4IOCP 3CMAR 1W2BQ 3CC4R 1VQ9R 3CF5P 1BXEA 2ZJQP 1VQ4R 1YIJR 1K8AS 2ZJPP 3G71R 4WFAP 5HL7P 5DM7P 3CCMR 1K9MS 1KC8S 1K73S 1JJ2Q 3J7YT 1I4JA 1VQMR 3PIOP 3CCQR 1QVFQ 3CC7R 1VQKR 1VQ6R 4U67P 5GADT 1M1KS 4WCEP 1Q7YS 5JVHP 3CCSR 5DM6P 3CCUR 1VQ7R 3CCER 1VQLR 5GAHT 1KD1S 4V19W 3CCLR 3G6ER 5MLCU 5GAET 1VQ8R 1YI2R 4IO9P 5JVGP 1Q81S 1M90S 3CC2R 1YHQR 3CMER 1NJIS 3DLLP 5GAGT 5H1SU 2QEXR 1QVGQ 3CXCQ 1VQOR 4WFNP 1YJWR 3CD6R 3J7ZS 3CCRR 3OW2Q 4UY8S 1YJNR 3PIPP 1YITR 3I56R 2ZJRP 2QA4R 3I55R 4WFBP 1Q86S 1VQNR 1VQPR 1KQSQ 3CCVR 1VQ5R 1Q82S 3CPWQ
chains in the Genus database with same CATH superfamily
1F7TA 3G4SR 4IOAP 3CCJR 1YJ9R 2OTLR 2OTJR 3NE3B 4WF9P 1N8RS 1S72R 4IOCP 3CMAR 3HQJA 1QR0A 1W2BQ 3CC4R 1FTEA 3CF5P 1VQ9R 1BXEA 2ZJQP 2CG5A 4JM7A 1VQ4R 1FTFA 3QMNA 2WDSA 1YIJR 1K8AS 2ZJPP 2WASA 3G71R 3NFDA 4MRTA 3H7QA 4WFAP 5HL7P 5DM7P 3CCMR 1K9MS 3GWMA 1KC8S 1K73S 1JJ2Q 1I4JA 3J7YT 1VQMR 3PIOP 3CCQR 1QVFQ 3HYKA 2WDOA 3CC7R 1VQKR 4DXEA 1VQ6R 4U67P 5GADT 2WATA 1M1KS 4WCEP 1Q7YS 2WASB 5JVHP 3CCSR 5DM6P 1NBWA 3CCUR 1VQ7R 3CCER 1VQLR 5GAHT 5CXDA 1KD1S 5CMOA 4V19W 2D0OA 3CCLR 3NE9A 3G6ER 5MLCU 5GAET 1VQ8R 1YI2R 2JBZA 4IO9P 5JVGP 1Q81S 1M90S 3CC2R 2BYDA 1YHQR 3CMER 2C43A 1NJIS 3DLLP 5GAGT 5H1SU 2QEXR 2WDYA 1QVGQ 1F80A 3CXCQ 1VQOR 4WFNP 4HC6A 1YJWR 3CD6R 3J7ZS 3CCRR 2JCAA 3OW2Q 3NE1A 4UY8S 1YJNR 3PIPP 1YITR 3I56R 2ZJRP 2QA4R 3I55R 4WFBP 2QG8A 1Q86S 1FTHA 2BDDA 1VQNR 1VQPR 1KQSQ 3CCVR 2D0PA 1VQ5R 1F7LA 1Q82S 3CPWQ
chains in the Genus database with same CATH topology
3G4SR 4IOAP 3CCJR 1YJ9R 2OTLR 2OTJR 4WF9P 1N8RS 1S72R 4IOCP 3CMAR 1W2BQ 3CC4R 1VQ9R 3CF5P 1BXEA 2ZJQP 1VQ4R 1YIJR 1K8AS 2ZJPP 3G71R 4WFAP 5HL7P 5DM7P 3CCMR 1K9MS 1KC8S 1K73S 1JJ2Q 3J7YT 1I4JA 1VQMR 3PIOP 3CCQR 1QVFQ 3CC7R 1VQKR 1VQ6R 4U67P 5GADT 1M1KS 4WCEP 1Q7YS 5JVHP 3CCSR 5DM6P 3CCUR 1VQ7R 3CCER 1VQLR 5GAHT 1KD1S 4V19W 3CCLR 3G6ER 5MLCU 5GAET 1VQ8R 1YI2R 4IO9P 5JVGP 1Q81S 1M90S 3CC2R 1YHQR 3CMER 1NJIS 3DLLP 5GAGT 5H1SU 2QEXR 1QVGQ 3CXCQ 1VQOR 4WFNP 1YJWR 3CD6R 3J7ZS 3CCRR 3OW2Q 4UY8S 1YJNR 3PIPP 1YITR 3I56R 2ZJRP 2QA4R 3I55R 4WFBP 1Q86S 1VQNR 1VQPR 1KQSQ 3CCVR 1VQ5R 1Q82S 3CPWQ
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G4S R;  4IOA P;  3CCJ R;  1YJ9 R;  2OTL R;  2OTJ R;  4WF9 P;  1N8R S;  1S72 R;  4IOC P;  3CMA R;  1W2B Q;  3CC4 R;  1VQ9 R;  3CF5 P;  1BXE A;  2ZJQ P;  1VQ4 R;  1YIJ R;  1K8A S;  2ZJP P;  3G71 R;  4WFA P;  5HL7 P;  5DM7 P;  3CCM R;  1K9M S;  1KC8 S;  1K73 S;  1JJ2 Q;  3J7Y T;  1I4J A;  1VQM R;  3PIO P;  3CCQ R;  1QVF Q;  3CC7 R;  1VQK R;  1VQ6 R;  4U67 P;  5GAD T;  1M1K S;  4WCE P;  1Q7Y S;  5JVH P;  3CCS R;  5DM6 P;  3CCU R;  1VQ7 R;  3CCE R;  1VQL R;  5GAH T;  1KD1 S;  4V19 W;  3CCL R;  3G6E R;  5MLC U;  5GAE T;  1VQ8 R;  1YI2 R;  4IO9 P;  5JVG P;  1Q81 S;  1M90 S;  3CC2 R;  1YHQ R;  3CME R;  1NJI S;  3DLL P;  5GAG T;  5H1S U;  2QEX R;  1QVG Q;  3CXC Q;  1VQO R;  4WFN P;  1YJW R;  3CD6 R;  3J7Z S;  3CCR R;  3OW2 Q;  4UY8 S;  1YJN R;  3PIP P;  1YIT R;  3I56 R;  2ZJR P;  2QA4 R;  3I55 R;  4WFB P;  1Q86 S;  1VQN R;  1VQP R;  1KQS Q;  3CCV R;  1VQ5 R;  1Q82 S;  3CPW Q; 
#chains in the Genus database with same CATH topology
 1F7T A;  3G4S R;  4IOA P;  3CCJ R;  1YJ9 R;  2OTL R;  2OTJ R;  3NE3 B;  4WF9 P;  1N8R S;  1S72 R;  4IOC P;  3CMA R;  3HQJ A;  1QR0 A;  1W2B Q;  3CC4 R;  1FTE A;  3CF5 P;  1VQ9 R;  1BXE A;  2ZJQ P;  2CG5 A;  4JM7 A;  1VQ4 R;  1FTF A;  3QMN A;  2WDS A;  1YIJ R;  1K8A S;  2ZJP P;  2WAS A;  3G71 R;  3NFD A;  4MRT A;  3H7Q A;  4WFA P;  5HL7 P;  5DM7 P;  3CCM R;  1K9M S;  3GWM A;  1KC8 S;  1K73 S;  1JJ2 Q;  1I4J A;  3J7Y T;  1VQM R;  3PIO P;  3CCQ R;  1QVF Q;  3HYK A;  2WDO A;  3CC7 R;  1VQK R;  4DXE A;  1VQ6 R;  4U67 P;  5GAD T;  2WAT A;  1M1K S;  4WCE P;  1Q7Y S;  2WAS B;  5JVH P;  3CCS R;  5DM6 P;  1NBW A;  3CCU R;  1VQ7 R;  3CCE R;  1VQL R;  5GAH T;  5CXD A;  1KD1 S;  5CMO A;  4V19 W;  2D0O A;  3CCL R;  3NE9 A;  3G6E R;  5MLC U;  5GAE T;  1VQ8 R;  1YI2 R;  2JBZ A;  4IO9 P;  5JVG P;  1Q81 S;  1M90 S;  3CC2 R;  2BYD A;  1YHQ R;  3CME R;  2C43 A;  1NJI S;  3DLL P;  5GAG T;  5H1S U;  2QEX R;  2WDY A;  1QVG Q;  1F80 A;  3CXC Q;  1VQO R;  4WFN P;  4HC6 A;  1YJW R;  3CD6 R;  3J7Z S;  3CCR R;  2JCA A;  3OW2 Q;  3NE1 A;  4UY8 S;  1YJN R;  3PIP P;  1YIT R;  3I56 R;  2ZJR P;  2QA4 R;  3I55 R;  4WFB P;  2QG8 A;  1Q86 S;  1FTH A;  2BDD A;  1VQN R;  1VQP R;  1KQS Q;  3CCV R;  2D0P A;  1VQ5 R;  1F7L A;  1Q82 S;  3CPW Q; 
#chains in the Genus database with same CATH homology
 3G4S R;  4IOA P;  3CCJ R;  1YJ9 R;  2OTL R;  2OTJ R;  4WF9 P;  1N8R S;  1S72 R;  4IOC P;  3CMA R;  1W2B Q;  3CC4 R;  1VQ9 R;  3CF5 P;  1BXE A;  2ZJQ P;  1VQ4 R;  1YIJ R;  1K8A S;  2ZJP P;  3G71 R;  4WFA P;  5HL7 P;  5DM7 P;  3CCM R;  1K9M S;  1KC8 S;  1K73 S;  1JJ2 Q;  3J7Y T;  1I4J A;  1VQM R;  3PIO P;  3CCQ R;  1QVF Q;  3CC7 R;  1VQK R;  1VQ6 R;  4U67 P;  5GAD T;  1M1K S;  4WCE P;  1Q7Y S;  5JVH P;  3CCS R;  5DM6 P;  3CCU R;  1VQ7 R;  3CCE R;  1VQL R;  5GAH T;  1KD1 S;  4V19 W;  3CCL R;  3G6E R;  5MLC U;  5GAE T;  1VQ8 R;  1YI2 R;  4IO9 P;  5JVG P;  1Q81 S;  1M90 S;  3CC2 R;  1YHQ R;  3CME R;  1NJI S;  3DLL P;  5GAG T;  5H1S U;  2QEX R;  1QVG Q;  3CXC Q;  1VQO R;  4WFN P;  1YJW R;  3CD6 R;  3J7Z S;  3CCR R;  3OW2 Q;  4UY8 S;  1YJN R;  3PIP P;  1YIT R;  3I56 R;  2ZJR P;  2QA4 R;  3I55 R;  4WFB P;  1Q86 S;  1VQN R;  1VQP R;  1KQS Q;  3CCV R;  1VQ5 R;  1Q82 S;  3CPW Q; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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