3CCER

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535a
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 40
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2008-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 3cceR00
1YJ9R 5DM7P 3CCSR 3CCUR 3CC2R 2OTJR 4WFNP 1YJNR 1K9MS 3CCVR 2ZJPP 1Q82S 3DLLP 5HL7P 1VQ9R 1VQ4R 1QVFQ 3CMER 5DM6P 1KC8S 3CPWQ 5JVHP 3CD6R 5GADT 1VQMR 1KQSQ 4WF9P 3CCQR 1I4JA 1Q81S 1JJ2Q 1VQLR 1M90S 3CXCQ 3J7YT 5GAET 1N8RS 1M1KS 1K73S 3I55R 5JVGP 1YITR 2ZJRP 1W2BQ 3G4SR 4WFBP 4IO9P 1S72R 2QA4R 3CCJR 3G6ER 1NJIS 1YIJR 4WCEP 5MLCU 1VQOR 1QVGQ 3CCER 3CCRR 1VQPR 1YJWR 1VQ6R 3PIOP 1YHQR 1Q86S 1VQ5R 1Q7YS 1VQNR 5H1SU 3J7ZS 2ZJQP 3CMAR 3CCLR 3OW2Q 3CF5P 5GAGT 1VQKR 4WFAP 3I56R 1VQ8R 5GAHT 3G71R 4IOAP 1K8AS 1YI2R 4UY8S 3PIPP 2QEXR 1BXEA 4IOCP 4U67P 1KD1S 2OTLR 3CC7R 1VQ7R 3CC4R 3CCMR 4V19W
chains in the Genus database with same CATH superfamily
1YJ9R 5DM7P 3CCSR 3CCUR 3CC2R 2OTJR 4WFNP 1YJNR 2WASA 3CCVR 1K9MS 1QR0A 1NBWA 2ZJPP 1Q82S 3DLLP 5HL7P 1VQ9R 1VQ4R 5CXDA 1QVFQ 3CMER 5DM6P 1KC8S 3CPWQ 4HC6A 5JVHP 3CD6R 2WASB 5GADT 1VQMR 2WATA 3NE3B 3CCQR 1FTEA 2CG5A 1I4JA 4WF9P 1Q81S 2D0PA 1JJ2Q 1KQSQ 1VQLR 3NE9A 1M90S 3CXCQ 1F7LA 3J7YT 5GAET 1N8RS 1M1KS 1F7TA 3I55R 1K73S 5JVGP 1YITR 3NE1A 2ZJRP 1W2BQ 3G4SR 4WFBP 3NFDA 2BYDA 1FTHA 4IO9P 2WDYA 1S72R 2QA4R 3CCJR 5CMOA 4JM7A 3G6ER 3HQJA 1NJIS 1YIJR 2C43A 4WCEP 5MLCU 1VQOR 1QVGQ 3CCER 3CCRR 1VQPR 1YJWR 1VQ6R 3PIOP 1F80A 1YHQR 3HYKA 1Q86S 3GWMA 1VQ5R 1Q7YS 1VQNR 5H1SU 2JCAA 3J7ZS 2ZJQP 3CMAR 3CCLR 3OW2Q 3CF5P 2D0OA 5GAGT 3QMNA 4WFAP 1VQKR 3I56R 1VQ8R 5GAHT 3G71R 4IOAP 1K8AS 2BDDA 2QG8A 1YI2R 4UY8S 3PIPP 4MRTA 2QEXR 1BXEA 1FTFA 4IOCP 4U67P 1KD1S 2WDOA 2OTLR 4DXEA 3H7QA 3CC7R 1VQ7R 2JBZA 3CC4R 3CCMR 4V19W 2WDSA
chains in the Genus database with same CATH topology
1YJ9R 5DM7P 3CCSR 3CCUR 3CC2R 2OTJR 4WFNP 1YJNR 1K9MS 3CCVR 2ZJPP 1Q82S 3DLLP 5HL7P 1VQ9R 1VQ4R 1QVFQ 3CMER 5DM6P 1KC8S 3CPWQ 5JVHP 3CD6R 5GADT 1VQMR 1KQSQ 4WF9P 3CCQR 1I4JA 1Q81S 1JJ2Q 1VQLR 1M90S 3CXCQ 3J7YT 5GAET 1N8RS 1M1KS 1K73S 3I55R 5JVGP 1YITR 2ZJRP 1W2BQ 3G4SR 4WFBP 4IO9P 1S72R 2QA4R 3CCJR 3G6ER 1NJIS 1YIJR 4WCEP 5MLCU 1VQOR 1QVGQ 3CCER 3CCRR 1VQPR 1YJWR 1VQ6R 3PIOP 1YHQR 1Q86S 1VQ5R 1Q7YS 1VQNR 5H1SU 3J7ZS 2ZJQP 3CMAR 3CCLR 3OW2Q 3CF5P 5GAGT 1VQKR 4WFAP 3I56R 1VQ8R 5GAHT 3G71R 4IOAP 1K8AS 1YI2R 4UY8S 3PIPP 2QEXR 1BXEA 4IOCP 4U67P 1KD1S 2OTLR 3CC7R 1VQ7R 3CC4R 3CCMR 4V19W
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YJ9 R;  5DM7 P;  3CCS R;  3CCU R;  3CC2 R;  2OTJ R;  4WFN P;  1YJN R;  1K9M S;  3CCV R;  2ZJP P;  1Q82 S;  3DLL P;  5HL7 P;  1VQ9 R;  1VQ4 R;  1QVF Q;  3CME R;  5DM6 P;  1KC8 S;  3CPW Q;  5JVH P;  3CD6 R;  5GAD T;  1VQM R;  1KQS Q;  4WF9 P;  3CCQ R;  1I4J A;  1Q81 S;  1JJ2 Q;  1VQL R;  1M90 S;  3CXC Q;  3J7Y T;  5GAE T;  1N8R S;  1M1K S;  1K73 S;  3I55 R;  5JVG P;  1YIT R;  2ZJR P;  1W2B Q;  3G4S R;  4WFB P;  4IO9 P;  1S72 R;  2QA4 R;  3CCJ R;  3G6E R;  1NJI S;  1YIJ R;  4WCE P;  5MLC U;  1VQO R;  1QVG Q;  3CCE R;  3CCR R;  1VQP R;  1YJW R;  1VQ6 R;  3PIO P;  1YHQ R;  1Q86 S;  1VQ5 R;  1Q7Y S;  1VQN R;  5H1S U;  3J7Z S;  2ZJQ P;  3CMA R;  3CCL R;  3OW2 Q;  3CF5 P;  5GAG T;  1VQK R;  4WFA P;  3I56 R;  1VQ8 R;  5GAH T;  3G71 R;  4IOA P;  1K8A S;  1YI2 R;  4UY8 S;  3PIP P;  2QEX R;  1BXE A;  4IOC P;  4U67 P;  1KD1 S;  2OTL R;  3CC7 R;  1VQ7 R;  3CC4 R;  3CCM R;  4V19 W; 
#chains in the Genus database with same CATH topology
 1YJ9 R;  5DM7 P;  3CCS R;  3CCU R;  3CC2 R;  2OTJ R;  4WFN P;  1YJN R;  2WAS A;  3CCV R;  1K9M S;  1QR0 A;  1NBW A;  2ZJP P;  1Q82 S;  3DLL P;  5HL7 P;  1VQ9 R;  1VQ4 R;  5CXD A;  1QVF Q;  3CME R;  5DM6 P;  1KC8 S;  3CPW Q;  4HC6 A;  5JVH P;  3CD6 R;  2WAS B;  5GAD T;  1VQM R;  2WAT A;  3NE3 B;  3CCQ R;  1FTE A;  2CG5 A;  1I4J A;  4WF9 P;  1Q81 S;  2D0P A;  1JJ2 Q;  1KQS Q;  1VQL R;  3NE9 A;  1M90 S;  3CXC Q;  1F7L A;  3J7Y T;  5GAE T;  1N8R S;  1M1K S;  1F7T A;  3I55 R;  1K73 S;  5JVG P;  1YIT R;  3NE1 A;  2ZJR P;  1W2B Q;  3G4S R;  4WFB P;  3NFD A;  2BYD A;  1FTH A;  4IO9 P;  2WDY A;  1S72 R;  2QA4 R;  3CCJ R;  5CMO A;  4JM7 A;  3G6E R;  3HQJ A;  1NJI S;  1YIJ R;  2C43 A;  4WCE P;  5MLC U;  1VQO R;  1QVG Q;  3CCE R;  3CCR R;  1VQP R;  1YJW R;  1VQ6 R;  3PIO P;  1F80 A;  1YHQ R;  3HYK A;  1Q86 S;  3GWM A;  1VQ5 R;  1Q7Y S;  1VQN R;  5H1S U;  2JCA A;  3J7Z S;  2ZJQ P;  3CMA R;  3CCL R;  3OW2 Q;  3CF5 P;  2D0O A;  5GAG T;  3QMN A;  4WFA P;  1VQK R;  3I56 R;  1VQ8 R;  5GAH T;  3G71 R;  4IOA P;  1K8A S;  2BDD A;  2QG8 A;  1YI2 R;  4UY8 S;  3PIP P;  4MRT A;  2QEX R;  1BXE A;  1FTF A;  4IOC P;  4U67 P;  1KD1 S;  2WDO A;  2OTL R;  4DXE A;  3H7Q A;  3CC7 R;  1VQ7 R;  2JBZ A;  3CC4 R;  3CCM R;  4V19 W;  2WDS A; 
#chains in the Genus database with same CATH homology
 1YJ9 R;  5DM7 P;  3CCS R;  3CCU R;  3CC2 R;  2OTJ R;  4WFN P;  1YJN R;  1K9M S;  3CCV R;  2ZJP P;  1Q82 S;  3DLL P;  5HL7 P;  1VQ9 R;  1VQ4 R;  1QVF Q;  3CME R;  5DM6 P;  1KC8 S;  3CPW Q;  5JVH P;  3CD6 R;  5GAD T;  1VQM R;  1KQS Q;  4WF9 P;  3CCQ R;  1I4J A;  1Q81 S;  1JJ2 Q;  1VQL R;  1M90 S;  3CXC Q;  3J7Y T;  5GAE T;  1N8R S;  1M1K S;  1K73 S;  3I55 R;  5JVG P;  1YIT R;  2ZJR P;  1W2B Q;  3G4S R;  4WFB P;  4IO9 P;  1S72 R;  2QA4 R;  3CCJ R;  3G6E R;  1NJI S;  1YIJ R;  4WCE P;  5MLC U;  1VQO R;  1QVG Q;  3CCE R;  3CCR R;  1VQP R;  1YJW R;  1VQ6 R;  3PIO P;  1YHQ R;  1Q86 S;  1VQ5 R;  1Q7Y S;  1VQN R;  5H1S U;  3J7Z S;  2ZJQ P;  3CMA R;  3CCL R;  3OW2 Q;  3CF5 P;  5GAG T;  1VQK R;  4WFA P;  3I56 R;  1VQ8 R;  5GAH T;  3G71 R;  4IOA P;  1K8A S;  1YI2 R;  4UY8 S;  3PIP P;  2QEX R;  1BXE A;  4IOC P;  4U67 P;  1KD1 S;  2OTL R;  3CC7 R;  1VQ7 R;  3CC4 R;  3CCM R;  4V19 W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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