3CCJR

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation c2534u
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 39
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 3ccjR00
3CF5P 1VQMR 4IOAP 3CMAR 4V19W 5GADT 5JVGP 1W2BQ 3DLLP 5DM6P 2QA4R 1S72R 3CC2R 3J7YT 1VQOR 1VQ4R 1YITR 3G4SR 1KC8S 3I55R 1QVGQ 2ZJRP 1VQ6R 1N8RS 1VQ7R 1QVFQ 2ZJQP 4IOCP 1YHQR 3CC7R 3CD6R 1VQLR 2QEXR 5HL7P 1VQNR 1KQSQ 2OTJR 1I4JA 4WCEP 1Q81S 1M1KS 4WFBP 3CPWQ 3PIPP 1Q86S 3CCVR 3CCQR 1NJIS 3CCJR 1M90S 1K8AS 5MLCU 4WFAP 1K9MS 1VQ8R 2OTLR 1VQ5R 1JJ2Q 1YI2R 5JVHP 1K73S 1VQ9R 5GAHT 4WF9P 3CCUR 5DM7P 5H1SU 1BXEA 3CXCQ 1YJNR 3PIOP 1KD1S 3G6ER 3I56R 4IO9P 1YIJR 1YJWR 1VQKR 1Q82S 3CC4R 3CCER 1YJ9R 4UY8S 2ZJPP 1Q7YS 1VQPR 3CCSR 3CMER 3CCLR 5GAGT 5GAET 4U67P 4WFNP 3OW2Q 3CCRR 3J7ZS 3G71R 3CCMR
chains in the Genus database with same CATH superfamily
3CF5P 1QR0A 1VQMR 4IOAP 3CMAR 4V19W 5GADT 5JVGP 1W2BQ 3DLLP 5DM6P 2QA4R 1S72R 3CC2R 3H7QA 2WASA 1F7TA 3J7YT 1FTHA 2C43A 1VQOR 2WDYA 1VQ4R 2D0OA 1YITR 3G4SR 1KC8S 3I55R 1QVGQ 2ZJRP 3NFDA 1VQ6R 2JCAA 1N8RS 1VQ7R 1QVFQ 2ZJQP 4IOCP 1YHQR 2CG5A 3CC7R 2WDOA 3CD6R 1NBWA 2BYDA 1VQLR 2QEXR 5HL7P 5CMOA 1VQNR 4HC6A 1KQSQ 2OTJR 1I4JA 4WCEP 3GWMA 1Q81S 1M1KS 4WFBP 3CPWQ 1FTFA 3PIPP 3HYKA 1Q86S 3CCVR 3CCQR 1NJIS 3CCJR 1M90S 1K8AS 2BDDA 4DXEA 2WASB 5MLCU 4WFAP 1K9MS 1F7LA 1VQ8R 2OTLR 2WDSA 1VQ5R 1JJ2Q 1YI2R 5JVHP 1K73S 1VQ9R 5GAHT 5CXDA 4WF9P 3CCUR 4JM7A 5DM7P 3NE1A 1FTEA 5H1SU 1BXEA 3CXCQ 1YJNR 3PIOP 1KD1S 3G6ER 3I56R 3QMNA 4IO9P 1YIJR 1YJWR 2WATA 1Q82S 2JBZA 1VQKR 3CC4R 3CCER 2QG8A 2D0PA 1F80A 1YJ9R 2ZJPP 4UY8S 1Q7YS 1VQPR 4MRTA 3CCSR 3CMER 3CCLR 5GAET 5GAGT 4U67P 4WFNP 3OW2Q 3CCRR 3NE9A 3J7ZS 3HQJA 3NE3B 3G71R 3CCMR
chains in the Genus database with same CATH topology
3CF5P 1VQMR 4IOAP 3CMAR 4V19W 5GADT 5JVGP 1W2BQ 3DLLP 5DM6P 2QA4R 1S72R 3CC2R 3J7YT 1VQOR 1VQ4R 1YITR 3G4SR 1KC8S 3I55R 1QVGQ 2ZJRP 1VQ6R 1N8RS 1VQ7R 1QVFQ 2ZJQP 4IOCP 1YHQR 3CC7R 3CD6R 1VQLR 2QEXR 5HL7P 1VQNR 1KQSQ 2OTJR 1I4JA 4WCEP 1Q81S 1M1KS 4WFBP 3CPWQ 3PIPP 1Q86S 3CCVR 3CCQR 1NJIS 3CCJR 1M90S 1K8AS 5MLCU 4WFAP 1K9MS 1VQ8R 2OTLR 1VQ5R 1JJ2Q 1YI2R 5JVHP 1K73S 1VQ9R 5GAHT 4WF9P 3CCUR 5DM7P 5H1SU 1BXEA 3CXCQ 1YJNR 3PIOP 1KD1S 3G6ER 3I56R 4IO9P 1YIJR 1YJWR 1VQKR 1Q82S 3CC4R 3CCER 1YJ9R 4UY8S 2ZJPP 1Q7YS 1VQPR 3CCSR 3CMER 3CCLR 5GAGT 5GAET 4U67P 4WFNP 3OW2Q 3CCRR 3J7ZS 3G71R 3CCMR
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CF5 P;  1VQM R;  4IOA P;  3CMA R;  4V19 W;  5GAD T;  5JVG P;  1W2B Q;  3DLL P;  5DM6 P;  2QA4 R;  1S72 R;  3CC2 R;  3J7Y T;  1VQO R;  1VQ4 R;  1YIT R;  3G4S R;  1KC8 S;  3I55 R;  1QVG Q;  2ZJR P;  1VQ6 R;  1N8R S;  1VQ7 R;  1QVF Q;  2ZJQ P;  4IOC P;  1YHQ R;  3CC7 R;  3CD6 R;  1VQL R;  2QEX R;  5HL7 P;  1VQN R;  1KQS Q;  2OTJ R;  1I4J A;  4WCE P;  1Q81 S;  1M1K S;  4WFB P;  3CPW Q;  3PIP P;  1Q86 S;  3CCV R;  3CCQ R;  1NJI S;  3CCJ R;  1M90 S;  1K8A S;  5MLC U;  4WFA P;  1K9M S;  1VQ8 R;  2OTL R;  1VQ5 R;  1JJ2 Q;  1YI2 R;  5JVH P;  1K73 S;  1VQ9 R;  5GAH T;  4WF9 P;  3CCU R;  5DM7 P;  5H1S U;  1BXE A;  3CXC Q;  1YJN R;  3PIO P;  1KD1 S;  3G6E R;  3I56 R;  4IO9 P;  1YIJ R;  1YJW R;  1VQK R;  1Q82 S;  3CC4 R;  3CCE R;  1YJ9 R;  4UY8 S;  2ZJP P;  1Q7Y S;  1VQP R;  3CCS R;  3CME R;  3CCL R;  5GAG T;  5GAE T;  4U67 P;  4WFN P;  3OW2 Q;  3CCR R;  3J7Z S;  3G71 R;  3CCM R; 
#chains in the Genus database with same CATH topology
 3CF5 P;  1QR0 A;  1VQM R;  4IOA P;  3CMA R;  4V19 W;  5GAD T;  5JVG P;  1W2B Q;  3DLL P;  5DM6 P;  2QA4 R;  1S72 R;  3CC2 R;  3H7Q A;  2WAS A;  1F7T A;  3J7Y T;  1FTH A;  2C43 A;  1VQO R;  2WDY A;  1VQ4 R;  2D0O A;  1YIT R;  3G4S R;  1KC8 S;  3I55 R;  1QVG Q;  2ZJR P;  3NFD A;  1VQ6 R;  2JCA A;  1N8R S;  1VQ7 R;  1QVF Q;  2ZJQ P;  4IOC P;  1YHQ R;  2CG5 A;  3CC7 R;  2WDO A;  3CD6 R;  1NBW A;  2BYD A;  1VQL R;  2QEX R;  5HL7 P;  5CMO A;  1VQN R;  4HC6 A;  1KQS Q;  2OTJ R;  1I4J A;  4WCE P;  3GWM A;  1Q81 S;  1M1K S;  4WFB P;  3CPW Q;  1FTF A;  3PIP P;  3HYK A;  1Q86 S;  3CCV R;  3CCQ R;  1NJI S;  3CCJ R;  1M90 S;  1K8A S;  2BDD A;  4DXE A;  2WAS B;  5MLC U;  4WFA P;  1K9M S;  1F7L A;  1VQ8 R;  2OTL R;  2WDS A;  1VQ5 R;  1JJ2 Q;  1YI2 R;  5JVH P;  1K73 S;  1VQ9 R;  5GAH T;  5CXD A;  4WF9 P;  3CCU R;  4JM7 A;  5DM7 P;  3NE1 A;  1FTE A;  5H1S U;  1BXE A;  3CXC Q;  1YJN R;  3PIO P;  1KD1 S;  3G6E R;  3I56 R;  3QMN A;  4IO9 P;  1YIJ R;  1YJW R;  2WAT A;  1Q82 S;  2JBZ A;  1VQK R;  3CC4 R;  3CCE R;  2QG8 A;  2D0P A;  1F80 A;  1YJ9 R;  2ZJP P;  4UY8 S;  1Q7Y S;  1VQP R;  4MRT A;  3CCS R;  3CME R;  3CCL R;  5GAE T;  5GAG T;  4U67 P;  4WFN P;  3OW2 Q;  3CCR R;  3NE9 A;  3J7Z S;  3HQJ A;  3NE3 B;  3G71 R;  3CCM R; 
#chains in the Genus database with same CATH homology
 3CF5 P;  1VQM R;  4IOA P;  3CMA R;  4V19 W;  5GAD T;  5JVG P;  1W2B Q;  3DLL P;  5DM6 P;  2QA4 R;  1S72 R;  3CC2 R;  3J7Y T;  1VQO R;  1VQ4 R;  1YIT R;  3G4S R;  1KC8 S;  3I55 R;  1QVG Q;  2ZJR P;  1VQ6 R;  1N8R S;  1VQ7 R;  1QVF Q;  2ZJQ P;  4IOC P;  1YHQ R;  3CC7 R;  3CD6 R;  1VQL R;  2QEX R;  5HL7 P;  1VQN R;  1KQS Q;  2OTJ R;  1I4J A;  4WCE P;  1Q81 S;  1M1K S;  4WFB P;  3CPW Q;  3PIP P;  1Q86 S;  3CCV R;  3CCQ R;  1NJI S;  3CCJ R;  1M90 S;  1K8A S;  5MLC U;  4WFA P;  1K9M S;  1VQ8 R;  2OTL R;  1VQ5 R;  1JJ2 Q;  1YI2 R;  5JVH P;  1K73 S;  1VQ9 R;  5GAH T;  4WF9 P;  3CCU R;  5DM7 P;  5H1S U;  1BXE A;  3CXC Q;  1YJN R;  3PIO P;  1KD1 S;  3G6E R;  3I56 R;  4IO9 P;  1YIJ R;  1YJW R;  1VQK R;  1Q82 S;  3CC4 R;  3CCE R;  1YJ9 R;  4UY8 S;  2ZJP P;  1Q7Y S;  1VQP R;  3CCS R;  3CME R;  3CCL R;  5GAG T;  5GAE T;  4U67 P;  4WFN P;  3OW2 Q;  3CCR R;  3J7Z S;  3G71 R;  3CCM R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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