3CCLR

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535c. density for anisomycin is visible but not included in model.
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 38
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 3cclR00
1YJWR 1Q82S 1NJIS 3CXCQ 1VQMR 1KD1S 1VQ6R 3CCSR 1YITR 1W2BQ 5HL7P 3PIPP 4WCEP 1VQPR 5JVGP 5GAHT 4IO9P 1Q81S 3CMAR 1VQKR 5DM7P 5GAET 2OTLR 1YJ9R 1M90S 4WFAP 3CCMR 4IOAP 1QVGQ 4WF9P 1M1KS 1N8RS 3CCQR 2ZJPP 3CPWQ 3CMER 3G6ER 3PIOP 5GAGT 3J7ZS 2QEXR 1KQSQ 1YIJR 3CCVR 4U67P 1S72R 5H1SU 1Q86S 3J7YT 4WFNP 3CC7R 1VQ8R 3G4SR 3CD6R 1KC8S 1VQ7R 4V19W 1K73S 1YHQR 3I55R 2ZJRP 2QA4R 1VQLR 1BXEA 1I4JA 3CCJR 2OTJR 1K8AS 4WFBP 1YI2R 3OW2Q 3I56R 1VQNR 4IOCP 5DM6P 3G71R 2ZJQP 3CCUR 1YJNR 1VQ9R 5JVHP 1K9MS 1VQ4R 3CCLR 3DLLP 1Q7YS 1JJ2Q 4UY8S 3CC4R 3CF5P 1QVFQ 3CCER 3CCRR 5GADT 1VQOR 5MLCU 1VQ5R 3CC2R
chains in the Genus database with same CATH superfamily
3GWMA 1YJWR 1Q82S 1NJIS 3CXCQ 1VQMR 1KD1S 1VQ6R 3CCSR 1YITR 1W2BQ 5HL7P 3PIPP 2D0OA 3NE3B 4WCEP 3QMNA 1VQPR 2QG8A 5JVGP 5GAHT 4IO9P 1Q81S 3CMAR 1VQKR 5DM7P 5GAET 2OTLR 1YJ9R 1M90S 3HQJA 4DXEA 4WFAP 3CCMR 4IOAP 1QVGQ 2WASB 4WF9P 1M1KS 1N8RS 3CCQR 2ZJPP 1FTHA 1F7TA 2BDDA 3CPWQ 2JBZA 1F7LA 3CMER 2WATA 3G6ER 3PIOP 5GAGT 3J7ZS 2QEXR 1QR0A 1KQSQ 3CCVR 1YIJR 4U67P 1S72R 5H1SU 2WASA 4JM7A 1Q86S 2CG5A 3J7YT 2WDYA 4WFNP 3CC7R 1VQ8R 5CXDA 3G4SR 2JCAA 3CD6R 1KC8S 1VQ7R 3NFDA 4V19W 1K73S 1YHQR 3I55R 3HYKA 2ZJRP 1FTFA 2QA4R 1BXEA 1I4JA 3CCJR 1VQLR 2OTJR 1K8AS 4WFBP 1YI2R 3OW2Q 3I56R 3H7QA 1VQNR 4IOCP 5DM6P 3G71R 2ZJQP 3CCUR 5CMOA 1F80A 2D0PA 1YJNR 1VQ9R 5JVHP 1K9MS 1NBWA 2BYDA 1VQ4R 3CCLR 3DLLP 2WDSA 1Q7YS 3NE9A 1JJ2Q 3NE1A 1FTEA 4HC6A 4UY8S 3CC4R 3CF5P 2C43A 1QVFQ 4MRTA 3CCER 3CCRR 5GADT 2WDOA 1VQOR 5MLCU 1VQ5R 3CC2R
chains in the Genus database with same CATH topology
1YJWR 1Q82S 1NJIS 3CXCQ 1VQMR 1KD1S 1VQ6R 3CCSR 1YITR 1W2BQ 5HL7P 3PIPP 4WCEP 1VQPR 5JVGP 5GAHT 4IO9P 1Q81S 3CMAR 1VQKR 5DM7P 5GAET 2OTLR 1YJ9R 1M90S 4WFAP 3CCMR 4IOAP 1QVGQ 4WF9P 1M1KS 1N8RS 3CCQR 2ZJPP 3CPWQ 3CMER 3G6ER 3PIOP 5GAGT 3J7ZS 2QEXR 1KQSQ 1YIJR 3CCVR 4U67P 1S72R 5H1SU 1Q86S 3J7YT 4WFNP 3CC7R 1VQ8R 3G4SR 3CD6R 1KC8S 1VQ7R 4V19W 1K73S 1YHQR 3I55R 2ZJRP 2QA4R 1VQLR 1BXEA 1I4JA 3CCJR 2OTJR 1K8AS 4WFBP 1YI2R 3OW2Q 3I56R 1VQNR 4IOCP 5DM6P 3G71R 2ZJQP 3CCUR 1YJNR 1VQ9R 5JVHP 1K9MS 1VQ4R 3CCLR 3DLLP 1Q7YS 1JJ2Q 4UY8S 3CC4R 3CF5P 1QVFQ 3CCER 3CCRR 5GADT 1VQOR 5MLCU 1VQ5R 3CC2R
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YJW R;  1Q82 S;  1NJI S;  3CXC Q;  1VQM R;  1KD1 S;  1VQ6 R;  3CCS R;  1YIT R;  1W2B Q;  5HL7 P;  3PIP P;  4WCE P;  1VQP R;  5JVG P;  5GAH T;  4IO9 P;  1Q81 S;  3CMA R;  1VQK R;  5DM7 P;  5GAE T;  2OTL R;  1YJ9 R;  1M90 S;  4WFA P;  3CCM R;  4IOA P;  1QVG Q;  4WF9 P;  1M1K S;  1N8R S;  3CCQ R;  2ZJP P;  3CPW Q;  3CME R;  3G6E R;  3PIO P;  5GAG T;  3J7Z S;  2QEX R;  1KQS Q;  1YIJ R;  3CCV R;  4U67 P;  1S72 R;  5H1S U;  1Q86 S;  3J7Y T;  4WFN P;  3CC7 R;  1VQ8 R;  3G4S R;  3CD6 R;  1KC8 S;  1VQ7 R;  4V19 W;  1K73 S;  1YHQ R;  3I55 R;  2ZJR P;  2QA4 R;  1VQL R;  1BXE A;  1I4J A;  3CCJ R;  2OTJ R;  1K8A S;  4WFB P;  1YI2 R;  3OW2 Q;  3I56 R;  1VQN R;  4IOC P;  5DM6 P;  3G71 R;  2ZJQ P;  3CCU R;  1YJN R;  1VQ9 R;  5JVH P;  1K9M S;  1VQ4 R;  3CCL R;  3DLL P;  1Q7Y S;  1JJ2 Q;  4UY8 S;  3CC4 R;  3CF5 P;  1QVF Q;  3CCE R;  3CCR R;  5GAD T;  1VQO R;  5MLC U;  1VQ5 R;  3CC2 R; 
#chains in the Genus database with same CATH topology
 3GWM A;  1YJW R;  1Q82 S;  1NJI S;  3CXC Q;  1VQM R;  1KD1 S;  1VQ6 R;  3CCS R;  1YIT R;  1W2B Q;  5HL7 P;  3PIP P;  2D0O A;  3NE3 B;  4WCE P;  3QMN A;  1VQP R;  2QG8 A;  5JVG P;  5GAH T;  4IO9 P;  1Q81 S;  3CMA R;  1VQK R;  5DM7 P;  5GAE T;  2OTL R;  1YJ9 R;  1M90 S;  3HQJ A;  4DXE A;  4WFA P;  3CCM R;  4IOA P;  1QVG Q;  2WAS B;  4WF9 P;  1M1K S;  1N8R S;  3CCQ R;  2ZJP P;  1FTH A;  1F7T A;  2BDD A;  3CPW Q;  2JBZ A;  1F7L A;  3CME R;  2WAT A;  3G6E R;  3PIO P;  5GAG T;  3J7Z S;  2QEX R;  1QR0 A;  1KQS Q;  3CCV R;  1YIJ R;  4U67 P;  1S72 R;  5H1S U;  2WAS A;  4JM7 A;  1Q86 S;  2CG5 A;  3J7Y T;  2WDY A;  4WFN P;  3CC7 R;  1VQ8 R;  5CXD A;  3G4S R;  2JCA A;  3CD6 R;  1KC8 S;  1VQ7 R;  3NFD A;  4V19 W;  1K73 S;  1YHQ R;  3I55 R;  3HYK A;  2ZJR P;  1FTF A;  2QA4 R;  1BXE A;  1I4J A;  3CCJ R;  1VQL R;  2OTJ R;  1K8A S;  4WFB P;  1YI2 R;  3OW2 Q;  3I56 R;  3H7Q A;  1VQN R;  4IOC P;  5DM6 P;  3G71 R;  2ZJQ P;  3CCU R;  5CMO A;  1F80 A;  2D0P A;  1YJN R;  1VQ9 R;  5JVH P;  1K9M S;  1NBW A;  2BYD A;  1VQ4 R;  3CCL R;  3DLL P;  2WDS A;  1Q7Y S;  3NE9 A;  1JJ2 Q;  3NE1 A;  1FTE A;  4HC6 A;  4UY8 S;  3CC4 R;  3CF5 P;  2C43 A;  1QVF Q;  4MRT A;  3CCE R;  3CCR R;  5GAD T;  2WDO A;  1VQO R;  5MLC U;  1VQ5 R;  3CC2 R; 
#chains in the Genus database with same CATH homology
 1YJW R;  1Q82 S;  1NJI S;  3CXC Q;  1VQM R;  1KD1 S;  1VQ6 R;  3CCS R;  1YIT R;  1W2B Q;  5HL7 P;  3PIP P;  4WCE P;  1VQP R;  5JVG P;  5GAH T;  4IO9 P;  1Q81 S;  3CMA R;  1VQK R;  5DM7 P;  5GAE T;  2OTL R;  1YJ9 R;  1M90 S;  4WFA P;  3CCM R;  4IOA P;  1QVG Q;  4WF9 P;  1M1K S;  1N8R S;  3CCQ R;  2ZJP P;  3CPW Q;  3CME R;  3G6E R;  3PIO P;  5GAG T;  3J7Z S;  2QEX R;  1KQS Q;  1YIJ R;  3CCV R;  4U67 P;  1S72 R;  5H1S U;  1Q86 S;  3J7Y T;  4WFN P;  3CC7 R;  1VQ8 R;  3G4S R;  3CD6 R;  1KC8 S;  1VQ7 R;  4V19 W;  1K73 S;  1YHQ R;  3I55 R;  2ZJR P;  2QA4 R;  1VQL R;  1BXE A;  1I4J A;  3CCJ R;  2OTJ R;  1K8A S;  4WFB P;  1YI2 R;  3OW2 Q;  3I56 R;  1VQN R;  4IOC P;  5DM6 P;  3G71 R;  2ZJQ P;  3CCU R;  1YJN R;  1VQ9 R;  5JVH P;  1K9M S;  1VQ4 R;  3CCL R;  3DLL P;  1Q7Y S;  1JJ2 Q;  4UY8 S;  3CC4 R;  3CF5 P;  1QVF Q;  3CCE R;  3CCR R;  5GAD T;  1VQO R;  5MLC U;  1VQ5 R;  3CC2 R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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