3CCMR

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2611u
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 39
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 3ccmR00
3CCJR 3J7ZS 1M1KS 3CXCQ 3CCSR 2OTJR 3CC7R 4WFBP 3PIOP 3I56R 5DM7P 3G6ER 1KD1S 1VQPR 1VQ6R 1K9MS 3G4SR 2QA4R 3CD6R 1Q86S 1VQ4R 4U67P 4V19W 1N8RS 1BXEA 5GAHT 3CF5P 5JVHP 4WFAP 1VQ7R 3CCVR 3CCER 1YITR 3CMAR 3CCRR 5GADT 4WF9P 2ZJQP 3CCLR 1K8AS 5HL7P 3I55R 3CCUR 5DM6P 1VQOR 1VQ8R 1JJ2Q 4WCEP 1I4JA 3CC4R 4IOAP 4WFNP 2QEXR 1M90S 1YIJR 1VQ9R 1VQ5R 1Q7YS 1VQNR 1KC8S 1NJIS 1YJ9R 3CC2R 5H1SU 1YJNR 3PIPP 1VQMR 3OW2Q 1QVGQ 1VQKR 1KQSQ 1QVFQ 3J7YT 1Q82S 3CPWQ 1S72R 1Q81S 1YHQR 2ZJRP 5JVGP 3CCMR 3DLLP 5GAGT 1VQLR 4IO9P 2OTLR 2ZJPP 3CMER 1K73S 1YI2R 4UY8S 1YJWR 1W2BQ 5GAET 5MLCU 4IOCP 3CCQR 3G71R
chains in the Genus database with same CATH superfamily
3CCJR 3J7ZS 1M1KS 3CXCQ 3CCSR 2OTJR 3CC7R 3HQJA 4WFBP 3H7QA 3PIOP 3I56R 5DM7P 3G6ER 1KD1S 1VQPR 1VQ6R 1F80A 1K9MS 3G4SR 2QA4R 3G71R 3CD6R 2WASA 1Q86S 1VQ4R 4U67P 2WDOA 4V19W 2CG5A 4JM7A 1N8RS 1BXEA 2JBZA 5GAHT 3CF5P 5JVHP 1FTHA 3GWMA 4WFAP 2BDDA 2WATA 1VQ7R 3CCVR 3CCER 1YITR 3CMAR 3CCRR 5GADT 4WF9P 2ZJQP 3NE1A 3CCLR 1F7LA 1K8AS 5CXDA 5HL7P 3I55R 3CCUR 2BYDA 4MRTA 5DM6P 1VQOR 1VQ8R 2JCAA 1JJ2Q 4WCEP 1I4JA 1QR0A 3CC4R 4IOAP 4WFNP 2QEXR 2WDSA 1M90S 1YIJR 1VQ9R 1VQ5R 1Q7YS 1VQNR 1KC8S 1NJIS 1YJ9R 1FTFA 2C43A 3CC2R 5H1SU 1YJNR 3PIPP 1VQMR 3OW2Q 1QVGQ 1VQKR 1KQSQ 1QVFQ 3J7YT 1Q82S 4DXEA 3CPWQ 1S72R 2WDYA 4HC6A 1Q81S 2D0OA 1YHQR 2ZJRP 5JVGP 1NBWA 1F7TA 3CCMR 3DLLP 5GAGT 1VQLR 2D0PA 4IO9P 3NE9A 2OTLR 2ZJPP 3NFDA 1FTEA 3CMER 1K73S 1YI2R 2QG8A 3NE3B 4UY8S 1YJWR 1W2BQ 5CMOA 5GAET 3HYKA 3QMNA 5MLCU 4IOCP 3CCQR 2WASB
chains in the Genus database with same CATH topology
3CCJR 3J7ZS 1M1KS 3CXCQ 3CCSR 2OTJR 3CC7R 4WFBP 3PIOP 3I56R 5DM7P 3G6ER 1KD1S 1VQPR 1VQ6R 1K9MS 3G4SR 2QA4R 3CD6R 1Q86S 1VQ4R 4U67P 4V19W 1N8RS 1BXEA 5GAHT 3CF5P 5JVHP 4WFAP 1VQ7R 3CCVR 3CCER 1YITR 3CMAR 3CCRR 5GADT 4WF9P 2ZJQP 3CCLR 1K8AS 5HL7P 3I55R 3CCUR 5DM6P 1VQOR 1VQ8R 1JJ2Q 4WCEP 1I4JA 3CC4R 4IOAP 4WFNP 2QEXR 1M90S 1YIJR 1VQ9R 1VQ5R 1Q7YS 1VQNR 1KC8S 1NJIS 1YJ9R 3CC2R 5H1SU 1YJNR 3PIPP 1VQMR 3OW2Q 1QVGQ 1VQKR 1KQSQ 1QVFQ 3J7YT 1Q82S 3CPWQ 1S72R 1Q81S 1YHQR 2ZJRP 5JVGP 3CCMR 3DLLP 5GAGT 1VQLR 4IO9P 2OTLR 2ZJPP 3CMER 1K73S 1YI2R 4UY8S 1YJWR 1W2BQ 5GAET 5MLCU 4IOCP 3CCQR 3G71R
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCJ R;  3J7Z S;  1M1K S;  3CXC Q;  3CCS R;  2OTJ R;  3CC7 R;  4WFB P;  3PIO P;  3I56 R;  5DM7 P;  3G6E R;  1KD1 S;  1VQP R;  1VQ6 R;  1K9M S;  3G4S R;  2QA4 R;  3CD6 R;  1Q86 S;  1VQ4 R;  4U67 P;  4V19 W;  1N8R S;  1BXE A;  5GAH T;  3CF5 P;  5JVH P;  4WFA P;  1VQ7 R;  3CCV R;  3CCE R;  1YIT R;  3CMA R;  3CCR R;  5GAD T;  4WF9 P;  2ZJQ P;  3CCL R;  1K8A S;  5HL7 P;  3I55 R;  3CCU R;  5DM6 P;  1VQO R;  1VQ8 R;  1JJ2 Q;  4WCE P;  1I4J A;  3CC4 R;  4IOA P;  4WFN P;  2QEX R;  1M90 S;  1YIJ R;  1VQ9 R;  1VQ5 R;  1Q7Y S;  1VQN R;  1KC8 S;  1NJI S;  1YJ9 R;  3CC2 R;  5H1S U;  1YJN R;  3PIP P;  1VQM R;  3OW2 Q;  1QVG Q;  1VQK R;  1KQS Q;  1QVF Q;  3J7Y T;  1Q82 S;  3CPW Q;  1S72 R;  1Q81 S;  1YHQ R;  2ZJR P;  5JVG P;  3CCM R;  3DLL P;  5GAG T;  1VQL R;  4IO9 P;  2OTL R;  2ZJP P;  3CME R;  1K73 S;  1YI2 R;  4UY8 S;  1YJW R;  1W2B Q;  5GAE T;  5MLC U;  4IOC P;  3CCQ R;  3G71 R; 
#chains in the Genus database with same CATH topology
 3CCJ R;  3J7Z S;  1M1K S;  3CXC Q;  3CCS R;  2OTJ R;  3CC7 R;  3HQJ A;  4WFB P;  3H7Q A;  3PIO P;  3I56 R;  5DM7 P;  3G6E R;  1KD1 S;  1VQP R;  1VQ6 R;  1F80 A;  1K9M S;  3G4S R;  2QA4 R;  3G71 R;  3CD6 R;  2WAS A;  1Q86 S;  1VQ4 R;  4U67 P;  2WDO A;  4V19 W;  2CG5 A;  4JM7 A;  1N8R S;  1BXE A;  2JBZ A;  5GAH T;  3CF5 P;  5JVH P;  1FTH A;  3GWM A;  4WFA P;  2BDD A;  2WAT A;  1VQ7 R;  3CCV R;  3CCE R;  1YIT R;  3CMA R;  3CCR R;  5GAD T;  4WF9 P;  2ZJQ P;  3NE1 A;  3CCL R;  1F7L A;  1K8A S;  5CXD A;  5HL7 P;  3I55 R;  3CCU R;  2BYD A;  4MRT A;  5DM6 P;  1VQO R;  1VQ8 R;  2JCA A;  1JJ2 Q;  4WCE P;  1I4J A;  1QR0 A;  3CC4 R;  4IOA P;  4WFN P;  2QEX R;  2WDS A;  1M90 S;  1YIJ R;  1VQ9 R;  1VQ5 R;  1Q7Y S;  1VQN R;  1KC8 S;  1NJI S;  1YJ9 R;  1FTF A;  2C43 A;  3CC2 R;  5H1S U;  1YJN R;  3PIP P;  1VQM R;  3OW2 Q;  1QVG Q;  1VQK R;  1KQS Q;  1QVF Q;  3J7Y T;  1Q82 S;  4DXE A;  3CPW Q;  1S72 R;  2WDY A;  4HC6 A;  1Q81 S;  2D0O A;  1YHQ R;  2ZJR P;  5JVG P;  1NBW A;  1F7T A;  3CCM R;  3DLL P;  5GAG T;  1VQL R;  2D0P A;  4IO9 P;  3NE9 A;  2OTL R;  2ZJP P;  3NFD A;  1FTE A;  3CME R;  1K73 S;  1YI2 R;  2QG8 A;  3NE3 B;  4UY8 S;  1YJW R;  1W2B Q;  5CMO A;  5GAE T;  3HYK A;  3QMN A;  5MLC U;  4IOC P;  3CCQ R;  2WAS B; 
#chains in the Genus database with same CATH homology
 3CCJ R;  3J7Z S;  1M1K S;  3CXC Q;  3CCS R;  2OTJ R;  3CC7 R;  4WFB P;  3PIO P;  3I56 R;  5DM7 P;  3G6E R;  1KD1 S;  1VQP R;  1VQ6 R;  1K9M S;  3G4S R;  2QA4 R;  3CD6 R;  1Q86 S;  1VQ4 R;  4U67 P;  4V19 W;  1N8R S;  1BXE A;  5GAH T;  3CF5 P;  5JVH P;  4WFA P;  1VQ7 R;  3CCV R;  3CCE R;  1YIT R;  3CMA R;  3CCR R;  5GAD T;  4WF9 P;  2ZJQ P;  3CCL R;  1K8A S;  5HL7 P;  3I55 R;  3CCU R;  5DM6 P;  1VQO R;  1VQ8 R;  1JJ2 Q;  4WCE P;  1I4J A;  3CC4 R;  4IOA P;  4WFN P;  2QEX R;  1M90 S;  1YIJ R;  1VQ9 R;  1VQ5 R;  1Q7Y S;  1VQN R;  1KC8 S;  1NJI S;  1YJ9 R;  3CC2 R;  5H1S U;  1YJN R;  3PIP P;  1VQM R;  3OW2 Q;  1QVG Q;  1VQK R;  1KQS Q;  1QVF Q;  3J7Y T;  1Q82 S;  3CPW Q;  1S72 R;  1Q81 S;  1YHQ R;  2ZJR P;  5JVG P;  3CCM R;  3DLL P;  5GAG T;  1VQL R;  4IO9 P;  2OTL R;  2ZJP P;  3CME R;  1K73 S;  1YI2 R;  4UY8 S;  1YJW R;  1W2B Q;  5GAE T;  5MLC U;  4IOC P;  3CCQ R;  3G71 R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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