3CCQR

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488u
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 35
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 3ccqR00
3PIOP 1KD1S 2ZJPP 1VQKR 3CF5P 5MLCU 1K73S 4IOAP 1Q82S 2ZJRP 1VQ8R 4WFBP 5JVGP 1QVGQ 4IO9P 3CD6R 3CXCQ 1Q7YS 1VQ9R 1K8AS 2ZJQP 3CCMR 5JVHP 3CC7R 1Q86S 1YJWR 3CCRR 1YIJR 1NJIS 5H1SU 3I55R 1VQ5R 3CCLR 1K9MS 1W2BQ 1QVFQ 4IOCP 1YHQR 1BXEA 2OTLR 3PIPP 1N8RS 5GAHT 4V19W 1YITR 5HL7P 1VQOR 4WFNP 3CC2R 1VQPR 3CCSR 1M1KS 3J7ZS 1VQNR 3CC4R 3G71R 3I56R 1M90S 1VQLR 3CPWQ 3CCJR 3CCQR 1YJ9R 2QEXR 1YI2R 3G6ER 1VQMR 3OW2Q 1I4JA 5DM7P 5GADT 4WCEP 1VQ6R 3CCUR 3G4SR 4WFAP 4U67P 3CMAR 5GAET 1YJNR 1KC8S 5DM6P 1KQSQ 3CCER 5GAGT 4WF9P 1VQ4R 3CCVR 1S72R 2OTJR 1JJ2Q 3CMER 4UY8S 2QA4R 1VQ7R 3J7YT 1Q81S 3DLLP
chains in the Genus database with same CATH superfamily
2WDSA 3PIOP 1FTHA 4MRTA 1KD1S 2ZJPP 2WASB 1VQKR 3CF5P 2WDYA 5MLCU 3NE9A 1K73S 4IOAP 2WASA 1Q82S 2ZJRP 2CG5A 1VQ8R 4WFBP 5JVGP 1QVGQ 4IO9P 3CD6R 3GWMA 3CXCQ 1Q7YS 1FTEA 1K8AS 1VQ9R 2ZJQP 4DXEA 3CCMR 2WDOA 5JVHP 3CC7R 2JCAA 1Q86S 1YJWR 5CMOA 3CCRR 1YIJR 1NJIS 1NBWA 5H1SU 3I55R 1VQ5R 3CCLR 1K9MS 1W2BQ 2WATA 1QVFQ 4IOCP 1YHQR 1BXEA 2OTLR 3PIPP 1N8RS 3NFDA 5GAHT 4JM7A 4V19W 5HL7P 1YITR 4HC6A 1VQOR 4WFNP 1F7LA 3CC2R 1VQPR 2JBZA 3HQJA 3CCSR 1M1KS 3J7ZS 1VQNR 3CC4R 2D0OA 3G71R 3I56R 1M90S 3HYKA 1FTFA 1VQLR 1F80A 3CPWQ 3CCJR 3CCQR 3H7QA 1YJ9R 2QEXR 1YI2R 3G6ER 1VQMR 3OW2Q 3NE1A 2D0PA 1I4JA 5DM7P 5GADT 4WCEP 1VQ6R 5CXDA 3CCUR 3G4SR 4WFAP 4U67P 3CMAR 5GAET 1YJNR 1KC8S 3QMNA 5DM6P 1KQSQ 2BYDA 2QG8A 3CCER 5GAGT 1F7TA 4WF9P 1VQ4R 3NE3B 3CCVR 2BDDA 1S72R 1QR0A 2OTJR 1JJ2Q 3CMER 4UY8S 2C43A 2QA4R 1VQ7R 3J7YT 1Q81S 3DLLP
chains in the Genus database with same CATH topology
3PIOP 1KD1S 2ZJPP 1VQKR 3CF5P 5MLCU 1K73S 4IOAP 1Q82S 2ZJRP 1VQ8R 4WFBP 5JVGP 1QVGQ 4IO9P 3CD6R 3CXCQ 1Q7YS 1VQ9R 1K8AS 2ZJQP 3CCMR 5JVHP 3CC7R 1Q86S 1YJWR 3CCRR 1YIJR 1NJIS 5H1SU 3I55R 1VQ5R 3CCLR 1K9MS 1W2BQ 1QVFQ 4IOCP 1YHQR 1BXEA 2OTLR 3PIPP 1N8RS 5GAHT 4V19W 1YITR 5HL7P 1VQOR 4WFNP 3CC2R 1VQPR 3CCSR 1M1KS 3J7ZS 1VQNR 3CC4R 3G71R 3I56R 1M90S 1VQLR 3CPWQ 3CCJR 3CCQR 1YJ9R 2QEXR 1YI2R 3G6ER 1VQMR 3OW2Q 1I4JA 5DM7P 5GADT 4WCEP 1VQ6R 3CCUR 3G4SR 4WFAP 4U67P 3CMAR 5GAET 1YJNR 1KC8S 5DM6P 1KQSQ 3CCER 5GAGT 4WF9P 1VQ4R 3CCVR 1S72R 2OTJR 1JJ2Q 3CMER 4UY8S 2QA4R 1VQ7R 3J7YT 1Q81S 3DLLP
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PIO P;  1KD1 S;  2ZJP P;  1VQK R;  3CF5 P;  5MLC U;  1K73 S;  4IOA P;  1Q82 S;  2ZJR P;  1VQ8 R;  4WFB P;  5JVG P;  1QVG Q;  4IO9 P;  3CD6 R;  3CXC Q;  1Q7Y S;  1VQ9 R;  1K8A S;  2ZJQ P;  3CCM R;  5JVH P;  3CC7 R;  1Q86 S;  1YJW R;  3CCR R;  1YIJ R;  1NJI S;  5H1S U;  3I55 R;  1VQ5 R;  3CCL R;  1K9M S;  1W2B Q;  1QVF Q;  4IOC P;  1YHQ R;  1BXE A;  2OTL R;  3PIP P;  1N8R S;  5GAH T;  4V19 W;  1YIT R;  5HL7 P;  1VQO R;  4WFN P;  3CC2 R;  1VQP R;  3CCS R;  1M1K S;  3J7Z S;  1VQN R;  3CC4 R;  3G71 R;  3I56 R;  1M90 S;  1VQL R;  3CPW Q;  3CCJ R;  3CCQ R;  1YJ9 R;  2QEX R;  1YI2 R;  3G6E R;  1VQM R;  3OW2 Q;  1I4J A;  5DM7 P;  5GAD T;  4WCE P;  1VQ6 R;  3CCU R;  3G4S R;  4WFA P;  4U67 P;  3CMA R;  5GAE T;  1YJN R;  1KC8 S;  5DM6 P;  1KQS Q;  3CCE R;  5GAG T;  4WF9 P;  1VQ4 R;  3CCV R;  1S72 R;  2OTJ R;  1JJ2 Q;  3CME R;  4UY8 S;  2QA4 R;  1VQ7 R;  3J7Y T;  1Q81 S;  3DLL P; 
#chains in the Genus database with same CATH topology
 2WDS A;  3PIO P;  1FTH A;  4MRT A;  1KD1 S;  2ZJP P;  2WAS B;  1VQK R;  3CF5 P;  2WDY A;  5MLC U;  3NE9 A;  1K73 S;  4IOA P;  2WAS A;  1Q82 S;  2ZJR P;  2CG5 A;  1VQ8 R;  4WFB P;  5JVG P;  1QVG Q;  4IO9 P;  3CD6 R;  3GWM A;  3CXC Q;  1Q7Y S;  1FTE A;  1K8A S;  1VQ9 R;  2ZJQ P;  4DXE A;  3CCM R;  2WDO A;  5JVH P;  3CC7 R;  2JCA A;  1Q86 S;  1YJW R;  5CMO A;  3CCR R;  1YIJ R;  1NJI S;  1NBW A;  5H1S U;  3I55 R;  1VQ5 R;  3CCL R;  1K9M S;  1W2B Q;  2WAT A;  1QVF Q;  4IOC P;  1YHQ R;  1BXE A;  2OTL R;  3PIP P;  1N8R S;  3NFD A;  5GAH T;  4JM7 A;  4V19 W;  5HL7 P;  1YIT R;  4HC6 A;  1VQO R;  4WFN P;  1F7L A;  3CC2 R;  1VQP R;  2JBZ A;  3HQJ A;  3CCS R;  1M1K S;  3J7Z S;  1VQN R;  3CC4 R;  2D0O A;  3G71 R;  3I56 R;  1M90 S;  3HYK A;  1FTF A;  1VQL R;  1F80 A;  3CPW Q;  3CCJ R;  3CCQ R;  3H7Q A;  1YJ9 R;  2QEX R;  1YI2 R;  3G6E R;  1VQM R;  3OW2 Q;  3NE1 A;  2D0P A;  1I4J A;  5DM7 P;  5GAD T;  4WCE P;  1VQ6 R;  5CXD A;  3CCU R;  3G4S R;  4WFA P;  4U67 P;  3CMA R;  5GAE T;  1YJN R;  1KC8 S;  3QMN A;  5DM6 P;  1KQS Q;  2BYD A;  2QG8 A;  3CCE R;  5GAG T;  1F7T A;  4WF9 P;  1VQ4 R;  3NE3 B;  3CCV R;  2BDD A;  1S72 R;  1QR0 A;  2OTJ R;  1JJ2 Q;  3CME R;  4UY8 S;  2C43 A;  2QA4 R;  1VQ7 R;  3J7Y T;  1Q81 S;  3DLL P; 
#chains in the Genus database with same CATH homology
 3PIO P;  1KD1 S;  2ZJP P;  1VQK R;  3CF5 P;  5MLC U;  1K73 S;  4IOA P;  1Q82 S;  2ZJR P;  1VQ8 R;  4WFB P;  5JVG P;  1QVG Q;  4IO9 P;  3CD6 R;  3CXC Q;  1Q7Y S;  1VQ9 R;  1K8A S;  2ZJQ P;  3CCM R;  5JVH P;  3CC7 R;  1Q86 S;  1YJW R;  3CCR R;  1YIJ R;  1NJI S;  5H1S U;  3I55 R;  1VQ5 R;  3CCL R;  1K9M S;  1W2B Q;  1QVF Q;  4IOC P;  1YHQ R;  1BXE A;  2OTL R;  3PIP P;  1N8R S;  5GAH T;  4V19 W;  1YIT R;  5HL7 P;  1VQO R;  4WFN P;  3CC2 R;  1VQP R;  3CCS R;  1M1K S;  3J7Z S;  1VQN R;  3CC4 R;  3G71 R;  3I56 R;  1M90 S;  1VQL R;  3CPW Q;  3CCJ R;  3CCQ R;  1YJ9 R;  2QEX R;  1YI2 R;  3G6E R;  1VQM R;  3OW2 Q;  1I4J A;  5DM7 P;  5GAD T;  4WCE P;  1VQ6 R;  3CCU R;  3G4S R;  4WFA P;  4U67 P;  3CMA R;  5GAE T;  1YJN R;  1KC8 S;  5DM6 P;  1KQS Q;  3CCE R;  5GAG T;  4WF9 P;  1VQ4 R;  3CCV R;  1S72 R;  2OTJ R;  1JJ2 Q;  3CME R;  4UY8 S;  2QA4 R;  1VQ7 R;  3J7Y T;  1Q81 S;  3DLL P; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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