3CCRR

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488c. density for anisomycin is visible but not included in the model.
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 37
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 3ccrR00
1VQOR 3CCQR 1I4JA 2ZJQP 1KC8S 1VQ6R 4U67P 1YIJR 1YJWR 1Q86S 5JVHP 3CCRR 1S72R 5MLCU 1QVFQ 3DLLP 4UY8S 1W2BQ 1K73S 1N8RS 1BXEA 3CCJR 5JVGP 5DM7P 2ZJRP 4IOAP 1VQLR 3CMAR 4WFNP 5GAGT 1VQNR 3CCER 1YHQR 3CCVR 4V19W 3CPWQ 1QVGQ 3G4SR 3CC4R 2QEXR 1YI2R 1YJ9R 4WFAP 1JJ2Q 3CC2R 3CMER 4IO9P 3PIOP 5GADT 1YITR 5GAHT 4WFBP 3J7YT 3CD6R 3CCLR 4WF9P 3I56R 1M90S 3CCUR 1VQ4R 3CXCQ 1YJNR 1Q82S 5DM6P 1KQSQ 3G6ER 3G71R 2ZJPP 1KD1S 1Q81S 2OTLR 3OW2Q 1VQ9R 1VQMR 2OTJR 5HL7P 3PIPP 3CF5P 1VQ7R 3I55R 3CC7R 1VQ5R 5H1SU 5GAET 3CCMR 1Q7YS 1VQ8R 3J7ZS 3CCSR 4WCEP 4IOCP 1NJIS 1VQPR 1M1KS 1VQKR 2QA4R 1K9MS 1K8AS
chains in the Genus database with same CATH superfamily
1F7LA 3HYKA 1VQOR 3CCQR 1I4JA 3NE3B 2ZJQP 1KC8S 1VQ6R 4U67P 1YIJR 1YJWR 1Q86S 3NE1A 2CG5A 1F80A 5JVHP 3CCRR 1S72R 2BYDA 5MLCU 2WDOA 3DLLP 1QVFQ 4UY8S 1NBWA 1W2BQ 1K73S 1N8RS 2D0OA 2QG8A 1BXEA 3CCJR 5JVGP 5DM7P 2ZJRP 3GWMA 2D0PA 4JM7A 4IOAP 1VQLR 3CMAR 3H7QA 4WFNP 5GAGT 1VQNR 3CCER 1YHQR 3CCVR 4V19W 3CPWQ 1QVGQ 3QMNA 3G4SR 3CC4R 2WDYA 2QEXR 5CMOA 1YI2R 1YJ9R 4WFAP 1JJ2Q 3CC2R 3CMER 3PIOP 4IO9P 2WATA 5GADT 1YITR 5GAHT 1F7TA 4WFBP 3NFDA 3J7YT 3CD6R 3CCLR 2BDDA 4WF9P 3I56R 1M90S 3CCUR 2WASA 2WDSA 3NE9A 1VQ4R 3CXCQ 1YJNR 1Q82S 5DM6P 1KQSQ 1FTFA 3G6ER 3G71R 2ZJPP 1KD1S 1Q81S 2OTLR 3OW2Q 4HC6A 1VQ9R 4MRTA 1VQMR 2OTJR 5HL7P 3PIPP 3CF5P 1VQ7R 3I55R 3CC7R 1VQ5R 5H1SU 5GAET 3CCMR 1Q7YS 2JCAA 5CXDA 2C43A 1VQ8R 3HQJA 3J7ZS 3CCSR 4WCEP 4IOCP 1NJIS 1VQPR 4DXEA 1M1KS 1FTHA 2JBZA 1VQKR 2WASB 1FTEA 2QA4R 1K9MS 1QR0A 1K8AS
chains in the Genus database with same CATH topology
1VQOR 3CCQR 1I4JA 2ZJQP 1KC8S 1VQ6R 4U67P 1YIJR 1YJWR 1Q86S 5JVHP 3CCRR 1S72R 5MLCU 1QVFQ 3DLLP 4UY8S 1W2BQ 1K73S 1N8RS 1BXEA 3CCJR 5JVGP 5DM7P 2ZJRP 4IOAP 1VQLR 3CMAR 4WFNP 5GAGT 1VQNR 3CCER 1YHQR 3CCVR 4V19W 3CPWQ 1QVGQ 3G4SR 3CC4R 2QEXR 1YI2R 1YJ9R 4WFAP 1JJ2Q 3CC2R 3CMER 4IO9P 3PIOP 5GADT 1YITR 5GAHT 4WFBP 3J7YT 3CD6R 3CCLR 4WF9P 3I56R 1M90S 3CCUR 1VQ4R 3CXCQ 1YJNR 1Q82S 5DM6P 1KQSQ 3G6ER 3G71R 2ZJPP 1KD1S 1Q81S 2OTLR 3OW2Q 1VQ9R 1VQMR 2OTJR 5HL7P 3PIPP 3CF5P 1VQ7R 3I55R 3CC7R 1VQ5R 5H1SU 5GAET 3CCMR 1Q7YS 1VQ8R 3J7ZS 3CCSR 4WCEP 4IOCP 1NJIS 1VQPR 1M1KS 1VQKR 2QA4R 1K9MS 1K8AS
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQO R;  3CCQ R;  1I4J A;  2ZJQ P;  1KC8 S;  1VQ6 R;  4U67 P;  1YIJ R;  1YJW R;  1Q86 S;  5JVH P;  3CCR R;  1S72 R;  5MLC U;  1QVF Q;  3DLL P;  4UY8 S;  1W2B Q;  1K73 S;  1N8R S;  1BXE A;  3CCJ R;  5JVG P;  5DM7 P;  2ZJR P;  4IOA P;  1VQL R;  3CMA R;  4WFN P;  5GAG T;  1VQN R;  3CCE R;  1YHQ R;  3CCV R;  4V19 W;  3CPW Q;  1QVG Q;  3G4S R;  3CC4 R;  2QEX R;  1YI2 R;  1YJ9 R;  4WFA P;  1JJ2 Q;  3CC2 R;  3CME R;  4IO9 P;  3PIO P;  5GAD T;  1YIT R;  5GAH T;  4WFB P;  3J7Y T;  3CD6 R;  3CCL R;  4WF9 P;  3I56 R;  1M90 S;  3CCU R;  1VQ4 R;  3CXC Q;  1YJN R;  1Q82 S;  5DM6 P;  1KQS Q;  3G6E R;  3G71 R;  2ZJP P;  1KD1 S;  1Q81 S;  2OTL R;  3OW2 Q;  1VQ9 R;  1VQM R;  2OTJ R;  5HL7 P;  3PIP P;  3CF5 P;  1VQ7 R;  3I55 R;  3CC7 R;  1VQ5 R;  5H1S U;  5GAE T;  3CCM R;  1Q7Y S;  1VQ8 R;  3J7Z S;  3CCS R;  4WCE P;  4IOC P;  1NJI S;  1VQP R;  1M1K S;  1VQK R;  2QA4 R;  1K9M S;  1K8A S; 
#chains in the Genus database with same CATH topology
 1F7L A;  3HYK A;  1VQO R;  3CCQ R;  1I4J A;  3NE3 B;  2ZJQ P;  1KC8 S;  1VQ6 R;  4U67 P;  1YIJ R;  1YJW R;  1Q86 S;  3NE1 A;  2CG5 A;  1F80 A;  5JVH P;  3CCR R;  1S72 R;  2BYD A;  5MLC U;  2WDO A;  3DLL P;  1QVF Q;  4UY8 S;  1NBW A;  1W2B Q;  1K73 S;  1N8R S;  2D0O A;  2QG8 A;  1BXE A;  3CCJ R;  5JVG P;  5DM7 P;  2ZJR P;  3GWM A;  2D0P A;  4JM7 A;  4IOA P;  1VQL R;  3CMA R;  3H7Q A;  4WFN P;  5GAG T;  1VQN R;  3CCE R;  1YHQ R;  3CCV R;  4V19 W;  3CPW Q;  1QVG Q;  3QMN A;  3G4S R;  3CC4 R;  2WDY A;  2QEX R;  5CMO A;  1YI2 R;  1YJ9 R;  4WFA P;  1JJ2 Q;  3CC2 R;  3CME R;  3PIO P;  4IO9 P;  2WAT A;  5GAD T;  1YIT R;  5GAH T;  1F7T A;  4WFB P;  3NFD A;  3J7Y T;  3CD6 R;  3CCL R;  2BDD A;  4WF9 P;  3I56 R;  1M90 S;  3CCU R;  2WAS A;  2WDS A;  3NE9 A;  1VQ4 R;  3CXC Q;  1YJN R;  1Q82 S;  5DM6 P;  1KQS Q;  1FTF A;  3G6E R;  3G71 R;  2ZJP P;  1KD1 S;  1Q81 S;  2OTL R;  3OW2 Q;  4HC6 A;  1VQ9 R;  4MRT A;  1VQM R;  2OTJ R;  5HL7 P;  3PIP P;  3CF5 P;  1VQ7 R;  3I55 R;  3CC7 R;  1VQ5 R;  5H1S U;  5GAE T;  3CCM R;  1Q7Y S;  2JCA A;  5CXD A;  2C43 A;  1VQ8 R;  3HQJ A;  3J7Z S;  3CCS R;  4WCE P;  4IOC P;  1NJI S;  1VQP R;  4DXE A;  1M1K S;  1FTH A;  2JBZ A;  1VQK R;  2WAS B;  1FTE A;  2QA4 R;  1K9M S;  1QR0 A;  1K8A S; 
#chains in the Genus database with same CATH homology
 1VQO R;  3CCQ R;  1I4J A;  2ZJQ P;  1KC8 S;  1VQ6 R;  4U67 P;  1YIJ R;  1YJW R;  1Q86 S;  5JVH P;  3CCR R;  1S72 R;  5MLC U;  1QVF Q;  3DLL P;  4UY8 S;  1W2B Q;  1K73 S;  1N8R S;  1BXE A;  3CCJ R;  5JVG P;  5DM7 P;  2ZJR P;  4IOA P;  1VQL R;  3CMA R;  4WFN P;  5GAG T;  1VQN R;  3CCE R;  1YHQ R;  3CCV R;  4V19 W;  3CPW Q;  1QVG Q;  3G4S R;  3CC4 R;  2QEX R;  1YI2 R;  1YJ9 R;  4WFA P;  1JJ2 Q;  3CC2 R;  3CME R;  4IO9 P;  3PIO P;  5GAD T;  1YIT R;  5GAH T;  4WFB P;  3J7Y T;  3CD6 R;  3CCL R;  4WF9 P;  3I56 R;  1M90 S;  3CCU R;  1VQ4 R;  3CXC Q;  1YJN R;  1Q82 S;  5DM6 P;  1KQS Q;  3G6E R;  3G71 R;  2ZJP P;  1KD1 S;  1Q81 S;  2OTL R;  3OW2 Q;  1VQ9 R;  1VQM R;  2OTJ R;  5HL7 P;  3PIP P;  3CF5 P;  1VQ7 R;  3I55 R;  3CC7 R;  1VQ5 R;  5H1S U;  5GAE T;  3CCM R;  1Q7Y S;  1VQ8 R;  3J7Z S;  3CCS R;  4WCE P;  4IOC P;  1NJI S;  1VQP R;  1M1K S;  1VQK R;  2QA4 R;  1K9M S;  1K8A S; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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