3CCSR

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2482a
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 37
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 3ccsR00
1VQ9R 3CCRR 3CCSR 1YI2R 2ZJQP 5GAHT 3J7YT 4WFAP 1YJWR 1N8RS 1KQSQ 1VQ4R 3DLLP 1YJ9R 4IOCP 1VQKR 3CF5P 5DM6P 3CC2R 1YJNR 4IO9P 3CPWQ 1VQ8R 5MLCU 1NJIS 1VQOR 2ZJPP 1Q81S 1VQMR 4WF9P 5DM7P 2OTLR 3CCJR 3CCUR 3CCLR 2QA4R 5JVGP 4V19W 5GADT 2OTJR 5H1SU 1VQ5R 3CXCQ 5GAGT 1BXEA 5JVHP 3I56R 1Q82S 5GAET 1YIJR 1VQ7R 1K9MS 2QEXR 1K8AS 1VQ6R 3CCER 3CCQR 4WFBP 1YHQR 3G4SR 3G71R 1KC8S 1VQPR 4WFNP 3CC7R 1KD1S 3OW2Q 3CCVR 1QVGQ 4WCEP 3I55R 1K73S 1QVFQ 4UY8S 1Q86S 5HL7P 3CMAR 1S72R 1VQLR 3J7ZS 1I4JA 3CCMR 1M90S 4U67P 1YITR 3CD6R 3G6ER 3PIPP 1Q7YS 3CC4R 1M1KS 1JJ2Q 4IOAP 1VQNR 3PIOP 2ZJRP 1W2BQ 3CMER
chains in the Genus database with same CATH superfamily
1VQ9R 3CCRR 3CCSR 1YI2R 3HQJA 5GAHT 2ZJQP 3J7YT 4WFAP 1YJWR 1N8RS 1KQSQ 1VQ4R 2JCAA 2WATA 3DLLP 1YJ9R 4IOCP 1VQKR 3CF5P 2ZJRP 5DM6P 2BYDA 3CC2R 1YJNR 3NE3B 4IO9P 3CPWQ 2JBZA 2WASB 1FTEA 1F7TA 1VQ8R 5MLCU 1NJIS 1VQOR 1F80A 2ZJPP 1Q81S 1VQMR 4WF9P 5DM7P 2OTLR 3CCJR 3CCUR 3CCLR 2QA4R 5JVGP 3QMNA 4V19W 5GADT 2OTJR 5H1SU 1VQ5R 3CXCQ 5GAGT 1BXEA 5JVHP 1QR0A 3I56R 1Q82S 5GAET 1YIJR 1VQ7R 1K9MS 2WDSA 3NE1A 2QEXR 3HYKA 1FTHA 1K8AS 3CCER 3CCQR 1VQ6R 4WFBP 1FTFA 2WASA 1YHQR 3G4SR 3G71R 1KC8S 1VQPR 1F7LA 4WFNP 3CC7R 5CMOA 2BDDA 3OW2Q 1KD1S 2WDYA 3CCVR 2QG8A 1QVGQ 4WCEP 4MRTA 3I55R 1K73S 1QVFQ 4HC6A 4UY8S 1Q86S 2WDOA 5HL7P 3CMAR 2CG5A 1S72R 1VQLR 3J7ZS 1I4JA 3CCMR 1M90S 3NFDA 4U67P 1YITR 3NE9A 4JM7A 3CD6R 2D0OA 3G6ER 4DXEA 1Q7YS 3CC4R 3H7QA 1M1KS 1JJ2Q 2D0PA 4IOAP 5CXDA 1NBWA 1VQNR 3GWMA 3PIOP 2C43A 3PIPP 1W2BQ 3CMER
chains in the Genus database with same CATH topology
1VQ9R 3CCRR 3CCSR 1YI2R 2ZJQP 5GAHT 3J7YT 4WFAP 1YJWR 1N8RS 1KQSQ 1VQ4R 3DLLP 1YJ9R 4IOCP 1VQKR 3CF5P 5DM6P 3CC2R 1YJNR 4IO9P 3CPWQ 1VQ8R 5MLCU 1NJIS 1VQOR 2ZJPP 1Q81S 1VQMR 4WF9P 5DM7P 2OTLR 3CCJR 3CCUR 3CCLR 2QA4R 5JVGP 4V19W 5GADT 2OTJR 5H1SU 1VQ5R 3CXCQ 5GAGT 1BXEA 5JVHP 3I56R 1Q82S 5GAET 1YIJR 1VQ7R 1K9MS 2QEXR 1K8AS 1VQ6R 3CCER 3CCQR 4WFBP 1YHQR 3G4SR 3G71R 1KC8S 1VQPR 4WFNP 3CC7R 1KD1S 3OW2Q 3CCVR 1QVGQ 4WCEP 3I55R 1K73S 1QVFQ 4UY8S 1Q86S 5HL7P 3CMAR 1S72R 1VQLR 3J7ZS 1I4JA 3CCMR 1M90S 4U67P 1YITR 3CD6R 3G6ER 3PIPP 1Q7YS 3CC4R 1M1KS 1JJ2Q 4IOAP 1VQNR 3PIOP 2ZJRP 1W2BQ 3CMER
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQ9 R;  3CCR R;  3CCS R;  1YI2 R;  2ZJQ P;  5GAH T;  3J7Y T;  4WFA P;  1YJW R;  1N8R S;  1KQS Q;  1VQ4 R;  3DLL P;  1YJ9 R;  4IOC P;  1VQK R;  3CF5 P;  5DM6 P;  3CC2 R;  1YJN R;  4IO9 P;  3CPW Q;  1VQ8 R;  5MLC U;  1NJI S;  1VQO R;  2ZJP P;  1Q81 S;  1VQM R;  4WF9 P;  5DM7 P;  2OTL R;  3CCJ R;  3CCU R;  3CCL R;  2QA4 R;  5JVG P;  4V19 W;  5GAD T;  2OTJ R;  5H1S U;  1VQ5 R;  3CXC Q;  5GAG T;  1BXE A;  5JVH P;  3I56 R;  1Q82 S;  5GAE T;  1YIJ R;  1VQ7 R;  1K9M S;  2QEX R;  1K8A S;  1VQ6 R;  3CCE R;  3CCQ R;  4WFB P;  1YHQ R;  3G4S R;  3G71 R;  1KC8 S;  1VQP R;  4WFN P;  3CC7 R;  1KD1 S;  3OW2 Q;  3CCV R;  1QVG Q;  4WCE P;  3I55 R;  1K73 S;  1QVF Q;  4UY8 S;  1Q86 S;  5HL7 P;  3CMA R;  1S72 R;  1VQL R;  3J7Z S;  1I4J A;  3CCM R;  1M90 S;  4U67 P;  1YIT R;  3CD6 R;  3G6E R;  3PIP P;  1Q7Y S;  3CC4 R;  1M1K S;  1JJ2 Q;  4IOA P;  1VQN R;  3PIO P;  2ZJR P;  1W2B Q;  3CME R; 
#chains in the Genus database with same CATH topology
 1VQ9 R;  3CCR R;  3CCS R;  1YI2 R;  3HQJ A;  5GAH T;  2ZJQ P;  3J7Y T;  4WFA P;  1YJW R;  1N8R S;  1KQS Q;  1VQ4 R;  2JCA A;  2WAT A;  3DLL P;  1YJ9 R;  4IOC P;  1VQK R;  3CF5 P;  2ZJR P;  5DM6 P;  2BYD A;  3CC2 R;  1YJN R;  3NE3 B;  4IO9 P;  3CPW Q;  2JBZ A;  2WAS B;  1FTE A;  1F7T A;  1VQ8 R;  5MLC U;  1NJI S;  1VQO R;  1F80 A;  2ZJP P;  1Q81 S;  1VQM R;  4WF9 P;  5DM7 P;  2OTL R;  3CCJ R;  3CCU R;  3CCL R;  2QA4 R;  5JVG P;  3QMN A;  4V19 W;  5GAD T;  2OTJ R;  5H1S U;  1VQ5 R;  3CXC Q;  5GAG T;  1BXE A;  5JVH P;  1QR0 A;  3I56 R;  1Q82 S;  5GAE T;  1YIJ R;  1VQ7 R;  1K9M S;  2WDS A;  3NE1 A;  2QEX R;  3HYK A;  1FTH A;  1K8A S;  3CCE R;  3CCQ R;  1VQ6 R;  4WFB P;  1FTF A;  2WAS A;  1YHQ R;  3G4S R;  3G71 R;  1KC8 S;  1VQP R;  1F7L A;  4WFN P;  3CC7 R;  5CMO A;  2BDD A;  3OW2 Q;  1KD1 S;  2WDY A;  3CCV R;  2QG8 A;  1QVG Q;  4WCE P;  4MRT A;  3I55 R;  1K73 S;  1QVF Q;  4HC6 A;  4UY8 S;  1Q86 S;  2WDO A;  5HL7 P;  3CMA R;  2CG5 A;  1S72 R;  1VQL R;  3J7Z S;  1I4J A;  3CCM R;  1M90 S;  3NFD A;  4U67 P;  1YIT R;  3NE9 A;  4JM7 A;  3CD6 R;  2D0O A;  3G6E R;  4DXE A;  1Q7Y S;  3CC4 R;  3H7Q A;  1M1K S;  1JJ2 Q;  2D0P A;  4IOA P;  5CXD A;  1NBW A;  1VQN R;  3GWM A;  3PIO P;  2C43 A;  3PIP P;  1W2B Q;  3CME R; 
#chains in the Genus database with same CATH homology
 1VQ9 R;  3CCR R;  3CCS R;  1YI2 R;  2ZJQ P;  5GAH T;  3J7Y T;  4WFA P;  1YJW R;  1N8R S;  1KQS Q;  1VQ4 R;  3DLL P;  1YJ9 R;  4IOC P;  1VQK R;  3CF5 P;  5DM6 P;  3CC2 R;  1YJN R;  4IO9 P;  3CPW Q;  1VQ8 R;  5MLC U;  1NJI S;  1VQO R;  2ZJP P;  1Q81 S;  1VQM R;  4WF9 P;  5DM7 P;  2OTL R;  3CCJ R;  3CCU R;  3CCL R;  2QA4 R;  5JVG P;  4V19 W;  5GAD T;  2OTJ R;  5H1S U;  1VQ5 R;  3CXC Q;  5GAG T;  1BXE A;  5JVH P;  3I56 R;  1Q82 S;  5GAE T;  1YIJ R;  1VQ7 R;  1K9M S;  2QEX R;  1K8A S;  1VQ6 R;  3CCE R;  3CCQ R;  4WFB P;  1YHQ R;  3G4S R;  3G71 R;  1KC8 S;  1VQP R;  4WFN P;  3CC7 R;  1KD1 S;  3OW2 Q;  3CCV R;  1QVG Q;  4WCE P;  3I55 R;  1K73 S;  1QVF Q;  4UY8 S;  1Q86 S;  5HL7 P;  3CMA R;  1S72 R;  1VQL R;  3J7Z S;  1I4J A;  3CCM R;  1M90 S;  4U67 P;  1YIT R;  3CD6 R;  3G6E R;  3PIP P;  1Q7Y S;  3CC4 R;  1M1K S;  1JJ2 Q;  4IOA P;  1VQN R;  3PIO P;  2ZJR P;  1W2B Q;  3CME R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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