3CCUR

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2482c
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 37
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 3ccuR00
3CMER 3CC2R 4IO9P 5HL7P 1KQSQ 4WFAP 5DM6P 3G71R 1VQNR 3CCUR 1K8AS 2QEXR 1VQLR 3PIPP 1YJNR 4WFBP 3CCLR 5DM7P 1VQMR 2OTJR 2ZJPP 1BXEA 1YJWR 1K9MS 1Q7YS 4WF9P 3CMAR 4U67P 1VQKR 4WFNP 1S72R 1VQPR 1VQ8R 3G6ER 1I4JA 5H1SU 4IOAP 1VQOR 3CC4R 3CCER 3G4SR 1VQ5R 1VQ9R 3J7ZS 3CCJR 1W2BQ 1YHQR 3OW2Q 3I55R 3CF5P 3CPWQ 1YITR 3CXCQ 5MLCU 1Q81S 5JVHP 1KC8S 1YI2R 1KD1S 1QVFQ 3CCMR 3CCQR 1Q86S 3CD6R 1YJ9R 1N8RS 1VQ4R 3DLLP 4V19W 5JVGP 3CC7R 5GAGT 3CCVR 2ZJQP 2ZJRP 4UY8S 1JJ2Q 2OTLR 3CCRR 1VQ7R 1QVGQ 1K73S 4IOCP 3PIOP 1M1KS 1YIJR 1M90S 1VQ6R 4WCEP 2QA4R 3J7YT 3I56R 1Q82S 5GAET 1NJIS 5GAHT 5GADT 3CCSR
chains in the Genus database with same CATH superfamily
3CMER 3NFDA 3CC2R 4IO9P 5HL7P 1KQSQ 4WFAP 2CG5A 5DM6P 2JCAA 4MRTA 3G71R 1VQNR 3CCUR 1K8AS 2QEXR 1VQLR 3PIPP 1QR0A 1YJNR 4WFBP 3CCLR 2BDDA 5DM7P 1VQMR 2OTJR 2ZJPP 1BXEA 1YJWR 1K9MS 1Q7YS 4WF9P 3CMAR 2WDYA 4U67P 1VQKR 4WFNP 1S72R 2D0PA 1VQPR 1VQ8R 3G6ER 1I4JA 3GWMA 2QG8A 2JBZA 5H1SU 1NBWA 4IOAP 1VQOR 3CC4R 3CCER 3G4SR 1VQ5R 1F80A 1VQ9R 3J7ZS 3CCJR 1W2BQ 1YHQR 3OW2Q 2WASB 3I55R 3CF5P 3NE3B 3CPWQ 2WDOA 2WASA 1YITR 1FTHA 5MLCU 3CXCQ 1Q81S 5JVHP 3HQJA 1KC8S 1YI2R 1KD1S 1QVFQ 3CCMR 3CCQR 1Q86S 3CD6R 1YJ9R 1N8RS 5CXDA 1VQ4R 3DLLP 1F7LA 4V19W 5JVGP 3HYKA 3CC7R 5GAGT 2C43A 2ZJQP 3CCVR 3NE1A 4HC6A 2ZJRP 4UY8S 1JJ2Q 2OTLR 5CMOA 3CCRR 1VQ7R 1QVGQ 1K73S 1FTEA 1F7TA 4IOCP 3PIOP 1M1KS 1YIJR 3QMNA 1M90S 2BYDA 1VQ6R 4WCEP 4JM7A 2QA4R 4DXEA 1FTFA 2WATA 3H7QA 3NE9A 3J7YT 3I56R 1Q82S 5GAET 1NJIS 5GAHT 2D0OA 2WDSA 5GADT 3CCSR
chains in the Genus database with same CATH topology
3CMER 3CC2R 4IO9P 5HL7P 1KQSQ 4WFAP 5DM6P 3G71R 1VQNR 3CCUR 1K8AS 2QEXR 1VQLR 3PIPP 1YJNR 4WFBP 3CCLR 5DM7P 1VQMR 2OTJR 2ZJPP 1BXEA 1YJWR 1K9MS 1Q7YS 4WF9P 3CMAR 4U67P 1VQKR 4WFNP 1S72R 1VQPR 1VQ8R 3G6ER 1I4JA 5H1SU 4IOAP 1VQOR 3CC4R 3CCER 3G4SR 1VQ5R 1VQ9R 3J7ZS 3CCJR 1W2BQ 1YHQR 3OW2Q 3I55R 3CF5P 3CPWQ 1YITR 3CXCQ 5MLCU 1Q81S 5JVHP 1KC8S 1YI2R 1KD1S 1QVFQ 3CCMR 3CCQR 1Q86S 3CD6R 1YJ9R 1N8RS 1VQ4R 3DLLP 4V19W 5JVGP 3CC7R 5GAGT 3CCVR 2ZJQP 2ZJRP 4UY8S 1JJ2Q 2OTLR 3CCRR 1VQ7R 1QVGQ 1K73S 4IOCP 3PIOP 1M1KS 1YIJR 1M90S 1VQ6R 4WCEP 2QA4R 3J7YT 3I56R 1Q82S 5GAET 1NJIS 5GAHT 5GADT 3CCSR
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CME R;  3CC2 R;  4IO9 P;  5HL7 P;  1KQS Q;  4WFA P;  5DM6 P;  3G71 R;  1VQN R;  3CCU R;  1K8A S;  2QEX R;  1VQL R;  3PIP P;  1YJN R;  4WFB P;  3CCL R;  5DM7 P;  1VQM R;  2OTJ R;  2ZJP P;  1BXE A;  1YJW R;  1K9M S;  1Q7Y S;  4WF9 P;  3CMA R;  4U67 P;  1VQK R;  4WFN P;  1S72 R;  1VQP R;  1VQ8 R;  3G6E R;  1I4J A;  5H1S U;  4IOA P;  1VQO R;  3CC4 R;  3CCE R;  3G4S R;  1VQ5 R;  1VQ9 R;  3J7Z S;  3CCJ R;  1W2B Q;  1YHQ R;  3OW2 Q;  3I55 R;  3CF5 P;  3CPW Q;  1YIT R;  3CXC Q;  5MLC U;  1Q81 S;  5JVH P;  1KC8 S;  1YI2 R;  1KD1 S;  1QVF Q;  3CCM R;  3CCQ R;  1Q86 S;  3CD6 R;  1YJ9 R;  1N8R S;  1VQ4 R;  3DLL P;  4V19 W;  5JVG P;  3CC7 R;  5GAG T;  3CCV R;  2ZJQ P;  2ZJR P;  4UY8 S;  1JJ2 Q;  2OTL R;  3CCR R;  1VQ7 R;  1QVG Q;  1K73 S;  4IOC P;  3PIO P;  1M1K S;  1YIJ R;  1M90 S;  1VQ6 R;  4WCE P;  2QA4 R;  3J7Y T;  3I56 R;  1Q82 S;  5GAE T;  1NJI S;  5GAH T;  5GAD T;  3CCS R; 
#chains in the Genus database with same CATH topology
 3CME R;  3NFD A;  3CC2 R;  4IO9 P;  5HL7 P;  1KQS Q;  4WFA P;  2CG5 A;  5DM6 P;  2JCA A;  4MRT A;  3G71 R;  1VQN R;  3CCU R;  1K8A S;  2QEX R;  1VQL R;  3PIP P;  1QR0 A;  1YJN R;  4WFB P;  3CCL R;  2BDD A;  5DM7 P;  1VQM R;  2OTJ R;  2ZJP P;  1BXE A;  1YJW R;  1K9M S;  1Q7Y S;  4WF9 P;  3CMA R;  2WDY A;  4U67 P;  1VQK R;  4WFN P;  1S72 R;  2D0P A;  1VQP R;  1VQ8 R;  3G6E R;  1I4J A;  3GWM A;  2QG8 A;  2JBZ A;  5H1S U;  1NBW A;  4IOA P;  1VQO R;  3CC4 R;  3CCE R;  3G4S R;  1VQ5 R;  1F80 A;  1VQ9 R;  3J7Z S;  3CCJ R;  1W2B Q;  1YHQ R;  3OW2 Q;  2WAS B;  3I55 R;  3CF5 P;  3NE3 B;  3CPW Q;  2WDO A;  2WAS A;  1YIT R;  1FTH A;  5MLC U;  3CXC Q;  1Q81 S;  5JVH P;  3HQJ A;  1KC8 S;  1YI2 R;  1KD1 S;  1QVF Q;  3CCM R;  3CCQ R;  1Q86 S;  3CD6 R;  1YJ9 R;  1N8R S;  5CXD A;  1VQ4 R;  3DLL P;  1F7L A;  4V19 W;  5JVG P;  3HYK A;  3CC7 R;  5GAG T;  2C43 A;  2ZJQ P;  3CCV R;  3NE1 A;  4HC6 A;  2ZJR P;  4UY8 S;  1JJ2 Q;  2OTL R;  5CMO A;  3CCR R;  1VQ7 R;  1QVG Q;  1K73 S;  1FTE A;  1F7T A;  4IOC P;  3PIO P;  1M1K S;  1YIJ R;  3QMN A;  1M90 S;  2BYD A;  1VQ6 R;  4WCE P;  4JM7 A;  2QA4 R;  4DXE A;  1FTF A;  2WAT A;  3H7Q A;  3NE9 A;  3J7Y T;  3I56 R;  1Q82 S;  5GAE T;  1NJI S;  5GAH T;  2D0O A;  2WDS A;  5GAD T;  3CCS R; 
#chains in the Genus database with same CATH homology
 3CME R;  3CC2 R;  4IO9 P;  5HL7 P;  1KQS Q;  4WFA P;  5DM6 P;  3G71 R;  1VQN R;  3CCU R;  1K8A S;  2QEX R;  1VQL R;  3PIP P;  1YJN R;  4WFB P;  3CCL R;  5DM7 P;  1VQM R;  2OTJ R;  2ZJP P;  1BXE A;  1YJW R;  1K9M S;  1Q7Y S;  4WF9 P;  3CMA R;  4U67 P;  1VQK R;  4WFN P;  1S72 R;  1VQP R;  1VQ8 R;  3G6E R;  1I4J A;  5H1S U;  4IOA P;  1VQO R;  3CC4 R;  3CCE R;  3G4S R;  1VQ5 R;  1VQ9 R;  3J7Z S;  3CCJ R;  1W2B Q;  1YHQ R;  3OW2 Q;  3I55 R;  3CF5 P;  3CPW Q;  1YIT R;  3CXC Q;  5MLC U;  1Q81 S;  5JVH P;  1KC8 S;  1YI2 R;  1KD1 S;  1QVF Q;  3CCM R;  3CCQ R;  1Q86 S;  3CD6 R;  1YJ9 R;  1N8R S;  1VQ4 R;  3DLL P;  4V19 W;  5JVG P;  3CC7 R;  5GAG T;  3CCV R;  2ZJQ P;  2ZJR P;  4UY8 S;  1JJ2 Q;  2OTL R;  3CCR R;  1VQ7 R;  1QVG Q;  1K73 S;  4IOC P;  3PIO P;  1M1K S;  1YIJ R;  1M90 S;  1VQ6 R;  4WCE P;  2QA4 R;  3J7Y T;  3I56 R;  1Q82 S;  5GAE T;  1NJI S;  5GAH T;  5GAD T;  3CCS R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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