3CCVR

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2616a
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 37
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 3ccvR00
2OTLR 3OW2Q 5H1SU 1S72R 1Q86S 1Q81S 3CMER 5GAGT 3PIPP 1I4JA 1NJIS 5GADT 1M1KS 1QVFQ 3G4SR 2ZJQP 3CC7R 1YITR 1K73S 3I55R 3CCVR 1N8RS 5DM6P 1KC8S 3CCQR 1JJ2Q 1YJNR 1VQMR 3CPWQ 3CF5P 1Q82S 3CCLR 4IOAP 4WF9P 4U67P 1VQPR 3J7ZS 4WCEP 3G71R 1YIJR 1VQKR 3CD6R 2QA4R 3PIOP 1M90S 3DLLP 3CCUR 3CCMR 3I56R 4IOCP 3CCRR 1YHQR 4WFNP 5JVHP 1VQ5R 3J7YT 2OTJR 1VQNR 3CCJR 1VQ8R 3CCER 1VQ7R 1W2BQ 4IO9P 2ZJRP 3CXCQ 5JVGP 4WFBP 1YI2R 1K8AS 3CC2R 1VQOR 3G6ER 3CCSR 5GAET 1VQLR 1KQSQ 1Q7YS 1K9MS 4V19W 1VQ6R 1BXEA 1YJWR 1KD1S 5MLCU 2ZJPP 3CC4R 4UY8S 5DM7P 4WFAP 1VQ4R 5HL7P 2QEXR 5GAHT 1QVGQ 1YJ9R 3CMAR 1VQ9R
chains in the Genus database with same CATH superfamily
2OTLR 3OW2Q 5H1SU 1S72R 1Q86S 1Q81S 3CMER 5GAGT 4DXEA 3PIPP 1I4JA 1NJIS 5GADT 2C43A 2BDDA 1M1KS 1QVFQ 3G4SR 2ZJQP 3NE3B 3CC7R 1YITR 1K73S 3I55R 2D0OA 3CCVR 1N8RS 5DM6P 1KC8S 3CCQR 1JJ2Q 1YJNR 2WATA 1VQMR 3CPWQ 3CF5P 1Q82S 3NE9A 2WDOA 3QMNA 3CCLR 4IOAP 2WDSA 4WF9P 2WASA 4U67P 1VQPR 3J7ZS 4WCEP 2JBZA 2CG5A 3G71R 3GWMA 1YIJR 1VQKR 3CD6R 1QR0A 2QA4R 4JM7A 2BYDA 3PIOP 1M90S 3DLLP 3CCUR 3CCMR 3I56R 4IOCP 1NBWA 3CCRR 1YHQR 4WFNP 5JVHP 4MRTA 4HC6A 1VQ5R 3J7YT 2OTJR 1VQNR 3CCJR 1VQ8R 3CCER 1VQ7R 1W2BQ 4IO9P 2D0PA 2ZJRP 1F80A 3HQJA 3CXCQ 5JVGP 1FTHA 4WFBP 1YI2R 1K8AS 3CC2R 1VQOR 3G6ER 3H7QA 3CCSR 1FTEA 2JCAA 5GAET 3NFDA 1VQLR 1KQSQ 1Q7YS 5CMOA 1K9MS 4V19W 1VQ6R 1BXEA 2WASB 1YJWR 2WDYA 1KD1S 5MLCU 2ZJPP 3CC4R 4UY8S 1F7TA 5DM7P 4WFAP 1VQ4R 5HL7P 1F7LA 2QG8A 2QEXR 5GAHT 1QVGQ 1YJ9R 5CXDA 3NE1A 3HYKA 3CMAR 1FTFA 1VQ9R
chains in the Genus database with same CATH topology
2OTLR 3OW2Q 5H1SU 1S72R 1Q86S 1Q81S 3CMER 5GAGT 3PIPP 1I4JA 1NJIS 5GADT 1M1KS 1QVFQ 3G4SR 2ZJQP 3CC7R 1YITR 1K73S 3I55R 3CCVR 1N8RS 5DM6P 1KC8S 3CCQR 1JJ2Q 1YJNR 1VQMR 3CPWQ 3CF5P 1Q82S 3CCLR 4IOAP 4WF9P 4U67P 1VQPR 3J7ZS 4WCEP 3G71R 1YIJR 1VQKR 3CD6R 2QA4R 3PIOP 1M90S 3DLLP 3CCUR 3CCMR 3I56R 4IOCP 3CCRR 1YHQR 4WFNP 5JVHP 1VQ5R 3J7YT 2OTJR 1VQNR 3CCJR 1VQ8R 3CCER 1VQ7R 1W2BQ 4IO9P 2ZJRP 3CXCQ 5JVGP 4WFBP 1YI2R 1K8AS 3CC2R 1VQOR 3G6ER 3CCSR 5GAET 1VQLR 1KQSQ 1Q7YS 1K9MS 4V19W 1VQ6R 1BXEA 1YJWR 1KD1S 5MLCU 2ZJPP 3CC4R 4UY8S 5DM7P 4WFAP 1VQ4R 5HL7P 2QEXR 5GAHT 1QVGQ 1YJ9R 3CMAR 1VQ9R
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OTL R;  3OW2 Q;  5H1S U;  1S72 R;  1Q86 S;  1Q81 S;  3CME R;  5GAG T;  3PIP P;  1I4J A;  1NJI S;  5GAD T;  1M1K S;  1QVF Q;  3G4S R;  2ZJQ P;  3CC7 R;  1YIT R;  1K73 S;  3I55 R;  3CCV R;  1N8R S;  5DM6 P;  1KC8 S;  3CCQ R;  1JJ2 Q;  1YJN R;  1VQM R;  3CPW Q;  3CF5 P;  1Q82 S;  3CCL R;  4IOA P;  4WF9 P;  4U67 P;  1VQP R;  3J7Z S;  4WCE P;  3G71 R;  1YIJ R;  1VQK R;  3CD6 R;  2QA4 R;  3PIO P;  1M90 S;  3DLL P;  3CCU R;  3CCM R;  3I56 R;  4IOC P;  3CCR R;  1YHQ R;  4WFN P;  5JVH P;  1VQ5 R;  3J7Y T;  2OTJ R;  1VQN R;  3CCJ R;  1VQ8 R;  3CCE R;  1VQ7 R;  1W2B Q;  4IO9 P;  2ZJR P;  3CXC Q;  5JVG P;  4WFB P;  1YI2 R;  1K8A S;  3CC2 R;  1VQO R;  3G6E R;  3CCS R;  5GAE T;  1VQL R;  1KQS Q;  1Q7Y S;  1K9M S;  4V19 W;  1VQ6 R;  1BXE A;  1YJW R;  1KD1 S;  5MLC U;  2ZJP P;  3CC4 R;  4UY8 S;  5DM7 P;  4WFA P;  1VQ4 R;  5HL7 P;  2QEX R;  5GAH T;  1QVG Q;  1YJ9 R;  3CMA R;  1VQ9 R; 
#chains in the Genus database with same CATH topology
 2OTL R;  3OW2 Q;  5H1S U;  1S72 R;  1Q86 S;  1Q81 S;  3CME R;  5GAG T;  4DXE A;  3PIP P;  1I4J A;  1NJI S;  5GAD T;  2C43 A;  2BDD A;  1M1K S;  1QVF Q;  3G4S R;  2ZJQ P;  3NE3 B;  3CC7 R;  1YIT R;  1K73 S;  3I55 R;  2D0O A;  3CCV R;  1N8R S;  5DM6 P;  1KC8 S;  3CCQ R;  1JJ2 Q;  1YJN R;  2WAT A;  1VQM R;  3CPW Q;  3CF5 P;  1Q82 S;  3NE9 A;  2WDO A;  3QMN A;  3CCL R;  4IOA P;  2WDS A;  4WF9 P;  2WAS A;  4U67 P;  1VQP R;  3J7Z S;  4WCE P;  2JBZ A;  2CG5 A;  3G71 R;  3GWM A;  1YIJ R;  1VQK R;  3CD6 R;  1QR0 A;  2QA4 R;  4JM7 A;  2BYD A;  3PIO P;  1M90 S;  3DLL P;  3CCU R;  3CCM R;  3I56 R;  4IOC P;  1NBW A;  3CCR R;  1YHQ R;  4WFN P;  5JVH P;  4MRT A;  4HC6 A;  1VQ5 R;  3J7Y T;  2OTJ R;  1VQN R;  3CCJ R;  1VQ8 R;  3CCE R;  1VQ7 R;  1W2B Q;  4IO9 P;  2D0P A;  2ZJR P;  1F80 A;  3HQJ A;  3CXC Q;  5JVG P;  1FTH A;  4WFB P;  1YI2 R;  1K8A S;  3CC2 R;  1VQO R;  3G6E R;  3H7Q A;  3CCS R;  1FTE A;  2JCA A;  5GAE T;  3NFD A;  1VQL R;  1KQS Q;  1Q7Y S;  5CMO A;  1K9M S;  4V19 W;  1VQ6 R;  1BXE A;  2WAS B;  1YJW R;  2WDY A;  1KD1 S;  5MLC U;  2ZJP P;  3CC4 R;  4UY8 S;  1F7T A;  5DM7 P;  4WFA P;  1VQ4 R;  5HL7 P;  1F7L A;  2QG8 A;  2QEX R;  5GAH T;  1QVG Q;  1YJ9 R;  5CXD A;  3NE1 A;  3HYK A;  3CMA R;  1FTF A;  1VQ9 R; 
#chains in the Genus database with same CATH homology
 2OTL R;  3OW2 Q;  5H1S U;  1S72 R;  1Q86 S;  1Q81 S;  3CME R;  5GAG T;  3PIP P;  1I4J A;  1NJI S;  5GAD T;  1M1K S;  1QVF Q;  3G4S R;  2ZJQ P;  3CC7 R;  1YIT R;  1K73 S;  3I55 R;  3CCV R;  1N8R S;  5DM6 P;  1KC8 S;  3CCQ R;  1JJ2 Q;  1YJN R;  1VQM R;  3CPW Q;  3CF5 P;  1Q82 S;  3CCL R;  4IOA P;  4WF9 P;  4U67 P;  1VQP R;  3J7Z S;  4WCE P;  3G71 R;  1YIJ R;  1VQK R;  3CD6 R;  2QA4 R;  3PIO P;  1M90 S;  3DLL P;  3CCU R;  3CCM R;  3I56 R;  4IOC P;  3CCR R;  1YHQ R;  4WFN P;  5JVH P;  1VQ5 R;  3J7Y T;  2OTJ R;  1VQN R;  3CCJ R;  1VQ8 R;  3CCE R;  1VQ7 R;  1W2B Q;  4IO9 P;  2ZJR P;  3CXC Q;  5JVG P;  4WFB P;  1YI2 R;  1K8A S;  3CC2 R;  1VQO R;  3G6E R;  3CCS R;  5GAE T;  1VQL R;  1KQS Q;  1Q7Y S;  1K9M S;  4V19 W;  1VQ6 R;  1BXE A;  1YJW R;  1KD1 S;  5MLC U;  2ZJP P;  3CC4 R;  4UY8 S;  5DM7 P;  4WFA P;  1VQ4 R;  5HL7 P;  2QEX R;  5GAH T;  1QVG Q;  1YJ9 R;  3CMA R;  1VQ9 R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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