3CD6R

Co-cystal of large ribosomal subunit mutant g2616a with cc-puromycin
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 37
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 3cd6R00
1W2BQ 1M90S 2OTLR 1VQPR 3CC4R 2QEXR 1VQ8R 4WF9P 1NJIS 1VQLR 3CCLR 2ZJRP 1VQ6R 1QVFQ 3I56R 1K73S 3DLLP 1YI2R 3J7ZS 2ZJPP 1QVGQ 3CPWQ 3G4SR 3CC2R 4IO9P 3J7YT 1VQ9R 1YIJR 5JVHP 3CC7R 3CCRR 1YJ9R 1KC8S 1K8AS 4V19W 1YJNR 1K9MS 1JJ2Q 3CXCQ 4IOAP 1BXEA 3CMER 2OTJR 5HL7P 1KD1S 5GAGT 3CF5P 1VQ5R 3PIOP 1VQKR 3G71R 3CCQR 1I4JA 5MLCU 3CCMR 3CCER 3CCSR 4U67P 1YITR 1VQMR 1Q7YS 1VQNR 1YHQR 5JVGP 2ZJQP 4UY8S 1N8RS 5GAHT 5GAET 1VQ7R 1Q81S 4WFBP 3OW2Q 3CMAR 4WCEP 1S72R 4IOCP 4WFNP 1Q86S 3CCJR 1YJWR 5H1SU 5DM7P 3G6ER 4WFAP 5DM6P 1Q82S 3CCVR 1KQSQ 1M1KS 3CCUR 5GADT 3I55R 1VQOR 1VQ4R 2QA4R 3CD6R 3PIPP
chains in the Genus database with same CATH superfamily
1W2BQ 1M90S 3NE9A 2OTLR 1VQPR 4HC6A 3CC4R 2QEXR 1VQ8R 4WF9P 1NJIS 1VQLR 3CCLR 2ZJRP 1VQ6R 1QVFQ 4DXEA 2WDYA 3I56R 1K73S 3DLLP 2WDOA 1YI2R 3J7ZS 2ZJPP 1QVGQ 3CPWQ 3G4SR 3HYKA 3CC2R 4IO9P 3J7YT 1VQ9R 1YIJR 5JVHP 3CC7R 3CCRR 2CG5A 1YJ9R 3NE1A 1KC8S 1K8AS 4V19W 1F7LA 1YJNR 1K9MS 1JJ2Q 3CXCQ 4MRTA 4IOAP 1BXEA 3CMER 1F7TA 2OTJR 5HL7P 1KD1S 2JCAA 2BDDA 2BYDA 5GAGT 3CF5P 1VQ5R 3H7QA 3PIOP 5CMOA 4JM7A 1VQKR 3G71R 3HQJA 3NE3B 3CCQR 1FTHA 1I4JA 5MLCU 2WATA 3CCMR 3CCER 3CCSR 2C43A 4U67P 3GWMA 1YITR 1VQMR 1Q7YS 1VQNR 1YHQR 2D0PA 2WASB 1FTFA 5JVGP 2WDSA 2ZJQP 3NFDA 4UY8S 1N8RS 5GAHT 5GAET 5CXDA 1QR0A 1VQ7R 4WFBP 1Q81S 3OW2Q 3CMAR 4WCEP 1S72R 2D0OA 4IOCP 4WFNP 1Q86S 3CCJR 1YJWR 5H1SU 5DM7P 3G6ER 2WASA 4WFAP 5DM6P 1Q82S 1FTEA 3CCVR 1KQSQ 3QMNA 1M1KS 3CCUR 5GADT 3I55R 2JBZA 1VQOR 2QG8A 1VQ4R 2QA4R 1F80A 1NBWA 3CD6R 3PIPP
chains in the Genus database with same CATH topology
1W2BQ 1M90S 2OTLR 1VQPR 3CC4R 2QEXR 1VQ8R 4WF9P 1NJIS 1VQLR 3CCLR 2ZJRP 1VQ6R 1QVFQ 3I56R 1K73S 3DLLP 1YI2R 3J7ZS 2ZJPP 1QVGQ 3CPWQ 3G4SR 3CC2R 4IO9P 3J7YT 1VQ9R 1YIJR 5JVHP 3CC7R 3CCRR 1YJ9R 1KC8S 1K8AS 4V19W 1YJNR 1K9MS 1JJ2Q 3CXCQ 4IOAP 1BXEA 3CMER 2OTJR 5HL7P 1KD1S 5GAGT 3CF5P 1VQ5R 3PIOP 1VQKR 3G71R 3CCQR 1I4JA 5MLCU 3CCMR 3CCER 3CCSR 4U67P 1YITR 1VQMR 1Q7YS 1VQNR 1YHQR 5JVGP 2ZJQP 4UY8S 1N8RS 5GAHT 5GAET 1VQ7R 1Q81S 4WFBP 3OW2Q 3CMAR 4WCEP 1S72R 4IOCP 4WFNP 1Q86S 3CCJR 1YJWR 5H1SU 5DM7P 3G6ER 4WFAP 5DM6P 1Q82S 3CCVR 1KQSQ 1M1KS 3CCUR 5GADT 3I55R 1VQOR 1VQ4R 2QA4R 3CD6R 3PIPP
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W2B Q;  1M90 S;  2OTL R;  1VQP R;  3CC4 R;  2QEX R;  1VQ8 R;  4WF9 P;  1NJI S;  1VQL R;  3CCL R;  2ZJR P;  1VQ6 R;  1QVF Q;  3I56 R;  1K73 S;  3DLL P;  1YI2 R;  3J7Z S;  2ZJP P;  1QVG Q;  3CPW Q;  3G4S R;  3CC2 R;  4IO9 P;  3J7Y T;  1VQ9 R;  1YIJ R;  5JVH P;  3CC7 R;  3CCR R;  1YJ9 R;  1KC8 S;  1K8A S;  4V19 W;  1YJN R;  1K9M S;  1JJ2 Q;  3CXC Q;  4IOA P;  1BXE A;  3CME R;  2OTJ R;  5HL7 P;  1KD1 S;  5GAG T;  3CF5 P;  1VQ5 R;  3PIO P;  1VQK R;  3G71 R;  3CCQ R;  1I4J A;  5MLC U;  3CCM R;  3CCE R;  3CCS R;  4U67 P;  1YIT R;  1VQM R;  1Q7Y S;  1VQN R;  1YHQ R;  5JVG P;  2ZJQ P;  4UY8 S;  1N8R S;  5GAH T;  5GAE T;  1VQ7 R;  1Q81 S;  4WFB P;  3OW2 Q;  3CMA R;  4WCE P;  1S72 R;  4IOC P;  4WFN P;  1Q86 S;  3CCJ R;  1YJW R;  5H1S U;  5DM7 P;  3G6E R;  4WFA P;  5DM6 P;  1Q82 S;  3CCV R;  1KQS Q;  1M1K S;  3CCU R;  5GAD T;  3I55 R;  1VQO R;  1VQ4 R;  2QA4 R;  3CD6 R;  3PIP P; 
#chains in the Genus database with same CATH topology
 1W2B Q;  1M90 S;  3NE9 A;  2OTL R;  1VQP R;  4HC6 A;  3CC4 R;  2QEX R;  1VQ8 R;  4WF9 P;  1NJI S;  1VQL R;  3CCL R;  2ZJR P;  1VQ6 R;  1QVF Q;  4DXE A;  2WDY A;  3I56 R;  1K73 S;  3DLL P;  2WDO A;  1YI2 R;  3J7Z S;  2ZJP P;  1QVG Q;  3CPW Q;  3G4S R;  3HYK A;  3CC2 R;  4IO9 P;  3J7Y T;  1VQ9 R;  1YIJ R;  5JVH P;  3CC7 R;  3CCR R;  2CG5 A;  1YJ9 R;  3NE1 A;  1KC8 S;  1K8A S;  4V19 W;  1F7L A;  1YJN R;  1K9M S;  1JJ2 Q;  3CXC Q;  4MRT A;  4IOA P;  1BXE A;  3CME R;  1F7T A;  2OTJ R;  5HL7 P;  1KD1 S;  2JCA A;  2BDD A;  2BYD A;  5GAG T;  3CF5 P;  1VQ5 R;  3H7Q A;  3PIO P;  5CMO A;  4JM7 A;  1VQK R;  3G71 R;  3HQJ A;  3NE3 B;  3CCQ R;  1FTH A;  1I4J A;  5MLC U;  2WAT A;  3CCM R;  3CCE R;  3CCS R;  2C43 A;  4U67 P;  3GWM A;  1YIT R;  1VQM R;  1Q7Y S;  1VQN R;  1YHQ R;  2D0P A;  2WAS B;  1FTF A;  5JVG P;  2WDS A;  2ZJQ P;  3NFD A;  4UY8 S;  1N8R S;  5GAH T;  5GAE T;  5CXD A;  1QR0 A;  1VQ7 R;  4WFB P;  1Q81 S;  3OW2 Q;  3CMA R;  4WCE P;  1S72 R;  2D0O A;  4IOC P;  4WFN P;  1Q86 S;  3CCJ R;  1YJW R;  5H1S U;  5DM7 P;  3G6E R;  2WAS A;  4WFA P;  5DM6 P;  1Q82 S;  1FTE A;  3CCV R;  1KQS Q;  3QMN A;  1M1K S;  3CCU R;  5GAD T;  3I55 R;  2JBZ A;  1VQO R;  2QG8 A;  1VQ4 R;  2QA4 R;  1F80 A;  1NBW A;  3CD6 R;  3PIP P; 
#chains in the Genus database with same CATH homology
 1W2B Q;  1M90 S;  2OTL R;  1VQP R;  3CC4 R;  2QEX R;  1VQ8 R;  4WF9 P;  1NJI S;  1VQL R;  3CCL R;  2ZJR P;  1VQ6 R;  1QVF Q;  3I56 R;  1K73 S;  3DLL P;  1YI2 R;  3J7Z S;  2ZJP P;  1QVG Q;  3CPW Q;  3G4S R;  3CC2 R;  4IO9 P;  3J7Y T;  1VQ9 R;  1YIJ R;  5JVH P;  3CC7 R;  3CCR R;  1YJ9 R;  1KC8 S;  1K8A S;  4V19 W;  1YJN R;  1K9M S;  1JJ2 Q;  3CXC Q;  4IOA P;  1BXE A;  3CME R;  2OTJ R;  5HL7 P;  1KD1 S;  5GAG T;  3CF5 P;  1VQ5 R;  3PIO P;  1VQK R;  3G71 R;  3CCQ R;  1I4J A;  5MLC U;  3CCM R;  3CCE R;  3CCS R;  4U67 P;  1YIT R;  1VQM R;  1Q7Y S;  1VQN R;  1YHQ R;  5JVG P;  2ZJQ P;  4UY8 S;  1N8R S;  5GAH T;  5GAE T;  1VQ7 R;  1Q81 S;  4WFB P;  3OW2 Q;  3CMA R;  4WCE P;  1S72 R;  4IOC P;  4WFN P;  1Q86 S;  3CCJ R;  1YJW R;  5H1S U;  5DM7 P;  3G6E R;  4WFA P;  5DM6 P;  1Q82 S;  3CCV R;  1KQS Q;  1M1K S;  3CCU R;  5GAD T;  3I55 R;  1VQO R;  1VQ4 R;  2QA4 R;  3CD6 R;  3PIP P; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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