3CPWQ

The structure of the antibiotic linezolid bound to the large ribosomal subunit of haloarcula marismortui
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S RIBOSOMAL RNA
total genus 37
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2008-04-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
Q PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 3cpwQ00
4UY8S 3CCMR 1JJ2Q 3CCSR 3CXCQ 1KD1S 3CCVR 1K8AS 1YJ9R 5MLCU 1YJWR 3G4SR 1VQOR 1N8RS 1KQSQ 5DM6P 4IO9P 1YHQR 1VQ4R 1K73S 3CC7R 2QA4R 3G71R 3I56R 1NJIS 1YIJR 1BXEA 1Q81S 4IOAP 1YJNR 3CCQR 4IOCP 1VQ5R 1VQ7R 1M1KS 1VQ8R 3CD6R 4WFNP 1QVGQ 3CC4R 3CCRR 2ZJPP 1VQKR 4WFAP 3CCLR 2ZJQP 2ZJRP 1YI2R 5DM7P 1VQMR 1VQ9R 1QVFQ 5H1SU 3CMAR 5GAET 1Q82S 5JVGP 5HL7P 3CCUR 3DLLP 5GAGT 3OW2Q 1VQLR 4WF9P 1I4JA 5JVHP 1YITR 4WFBP 3CCJR 3CCER 1VQPR 1VQNR 1W2BQ 5GAHT 3CPWQ 1Q7YS 2OTJR 2OTLR 3G6ER 1KC8S 1Q86S 4V19W 3PIOP 1M90S 3J7YT 5GADT 4U67P 3PIPP 2QEXR 1VQ6R 3J7ZS 3CC2R 4WCEP 3CF5P 1S72R 3I55R 3CMER 1K9MS
chains in the Genus database with same CATH superfamily
3GWMA 4UY8S 3CCMR 5CXDA 1JJ2Q 2WASA 4DXEA 3CCSR 3CXCQ 1KD1S 3CCVR 1K8AS 1YJ9R 5MLCU 1YJWR 3G4SR 1VQOR 3NE3B 1N8RS 1KQSQ 5DM6P 4IO9P 1YHQR 1VQ4R 1K73S 4HC6A 3CC7R 2QA4R 2BDDA 3G71R 3NE1A 3I56R 1NJIS 3HYKA 1YIJR 1BXEA 1Q81S 4MRTA 4IOAP 1YJNR 3CCQR 3HQJA 4IOCP 1VQ5R 1VQ7R 1M1KS 1VQ8R 2BYDA 3CD6R 4WFNP 2QG8A 1QVGQ 3CC4R 1NBWA 3NFDA 3CCRR 2ZJPP 2C43A 1VQKR 4WFAP 1F7LA 2ZJQP 3CCLR 2CG5A 2WDOA 2ZJRP 1YI2R 5DM7P 1VQMR 1VQ9R 1QVFQ 5H1SU 3CMAR 2JCAA 4JM7A 3H7QA 5GAET 1Q82S 2D0OA 5JVGP 5HL7P 3CCUR 3NE9A 3DLLP 5GAGT 3OW2Q 1VQLR 2WDYA 4WF9P 1I4JA 5JVHP 1YITR 4WFBP 3CCJR 3CCER 1VQPR 1VQNR 1W2BQ 2D0PA 5GAHT 1FTHA 3CPWQ 5CMOA 1Q7YS 2OTJR 2WASB 2OTLR 3G6ER 1KC8S 1FTEA 1Q86S 1F7TA 4V19W 3PIOP 1M90S 3J7YT 1QR0A 3QMNA 5GADT 2JBZA 4U67P 3PIPP 2QEXR 1VQ6R 3J7ZS 3CC2R 2WDSA 1F80A 4WCEP 3CF5P 1FTFA 2WATA 1S72R 3I55R 3CMER 1K9MS
chains in the Genus database with same CATH topology
4UY8S 3CCMR 1JJ2Q 3CCSR 3CXCQ 1KD1S 3CCVR 1K8AS 1YJ9R 5MLCU 1YJWR 3G4SR 1VQOR 1N8RS 1KQSQ 5DM6P 4IO9P 1YHQR 1VQ4R 1K73S 3CC7R 2QA4R 3G71R 3I56R 1NJIS 1YIJR 1BXEA 1Q81S 4IOAP 1YJNR 3CCQR 4IOCP 1VQ5R 1VQ7R 1M1KS 1VQ8R 3CD6R 4WFNP 1QVGQ 3CC4R 3CCRR 2ZJPP 1VQKR 4WFAP 3CCLR 2ZJQP 2ZJRP 1YI2R 5DM7P 1VQMR 1VQ9R 1QVFQ 5H1SU 3CMAR 5GAET 1Q82S 5JVGP 5HL7P 3CCUR 3DLLP 5GAGT 3OW2Q 1VQLR 4WF9P 1I4JA 5JVHP 1YITR 4WFBP 3CCJR 3CCER 1VQPR 1VQNR 1W2BQ 5GAHT 3CPWQ 1Q7YS 2OTJR 2OTLR 3G6ER 1KC8S 1Q86S 4V19W 3PIOP 1M90S 3J7YT 5GADT 4U67P 3PIPP 2QEXR 1VQ6R 3J7ZS 3CC2R 4WCEP 3CF5P 1S72R 3I55R 3CMER 1K9MS
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UY8 S;  3CCM R;  1JJ2 Q;  3CCS R;  3CXC Q;  1KD1 S;  3CCV R;  1K8A S;  1YJ9 R;  5MLC U;  1YJW R;  3G4S R;  1VQO R;  1N8R S;  1KQS Q;  5DM6 P;  4IO9 P;  1YHQ R;  1VQ4 R;  1K73 S;  3CC7 R;  2QA4 R;  3G71 R;  3I56 R;  1NJI S;  1YIJ R;  1BXE A;  1Q81 S;  4IOA P;  1YJN R;  3CCQ R;  4IOC P;  1VQ5 R;  1VQ7 R;  1M1K S;  1VQ8 R;  3CD6 R;  4WFN P;  1QVG Q;  3CC4 R;  3CCR R;  2ZJP P;  1VQK R;  4WFA P;  3CCL R;  2ZJQ P;  2ZJR P;  1YI2 R;  5DM7 P;  1VQM R;  1VQ9 R;  1QVF Q;  5H1S U;  3CMA R;  5GAE T;  1Q82 S;  5JVG P;  5HL7 P;  3CCU R;  3DLL P;  5GAG T;  3OW2 Q;  1VQL R;  4WF9 P;  1I4J A;  5JVH P;  1YIT R;  4WFB P;  3CCJ R;  3CCE R;  1VQP R;  1VQN R;  1W2B Q;  5GAH T;  3CPW Q;  1Q7Y S;  2OTJ R;  2OTL R;  3G6E R;  1KC8 S;  1Q86 S;  4V19 W;  3PIO P;  1M90 S;  3J7Y T;  5GAD T;  4U67 P;  3PIP P;  2QEX R;  1VQ6 R;  3J7Z S;  3CC2 R;  4WCE P;  3CF5 P;  1S72 R;  3I55 R;  3CME R;  1K9M S; 
#chains in the Genus database with same CATH topology
 3GWM A;  4UY8 S;  3CCM R;  5CXD A;  1JJ2 Q;  2WAS A;  4DXE A;  3CCS R;  3CXC Q;  1KD1 S;  3CCV R;  1K8A S;  1YJ9 R;  5MLC U;  1YJW R;  3G4S R;  1VQO R;  3NE3 B;  1N8R S;  1KQS Q;  5DM6 P;  4IO9 P;  1YHQ R;  1VQ4 R;  1K73 S;  4HC6 A;  3CC7 R;  2QA4 R;  2BDD A;  3G71 R;  3NE1 A;  3I56 R;  1NJI S;  3HYK A;  1YIJ R;  1BXE A;  1Q81 S;  4MRT A;  4IOA P;  1YJN R;  3CCQ R;  3HQJ A;  4IOC P;  1VQ5 R;  1VQ7 R;  1M1K S;  1VQ8 R;  2BYD A;  3CD6 R;  4WFN P;  2QG8 A;  1QVG Q;  3CC4 R;  1NBW A;  3NFD A;  3CCR R;  2ZJP P;  2C43 A;  1VQK R;  4WFA P;  1F7L A;  2ZJQ P;  3CCL R;  2CG5 A;  2WDO A;  2ZJR P;  1YI2 R;  5DM7 P;  1VQM R;  1VQ9 R;  1QVF Q;  5H1S U;  3CMA R;  2JCA A;  4JM7 A;  3H7Q A;  5GAE T;  1Q82 S;  2D0O A;  5JVG P;  5HL7 P;  3CCU R;  3NE9 A;  3DLL P;  5GAG T;  3OW2 Q;  1VQL R;  2WDY A;  4WF9 P;  1I4J A;  5JVH P;  1YIT R;  4WFB P;  3CCJ R;  3CCE R;  1VQP R;  1VQN R;  1W2B Q;  2D0P A;  5GAH T;  1FTH A;  3CPW Q;  5CMO A;  1Q7Y S;  2OTJ R;  2WAS B;  2OTL R;  3G6E R;  1KC8 S;  1FTE A;  1Q86 S;  1F7T A;  4V19 W;  3PIO P;  1M90 S;  3J7Y T;  1QR0 A;  3QMN A;  5GAD T;  2JBZ A;  4U67 P;  3PIP P;  2QEX R;  1VQ6 R;  3J7Z S;  3CC2 R;  2WDS A;  1F80 A;  4WCE P;  3CF5 P;  1FTF A;  2WAT A;  1S72 R;  3I55 R;  3CME R;  1K9M S; 
#chains in the Genus database with same CATH homology
 4UY8 S;  3CCM R;  1JJ2 Q;  3CCS R;  3CXC Q;  1KD1 S;  3CCV R;  1K8A S;  1YJ9 R;  5MLC U;  1YJW R;  3G4S R;  1VQO R;  1N8R S;  1KQS Q;  5DM6 P;  4IO9 P;  1YHQ R;  1VQ4 R;  1K73 S;  3CC7 R;  2QA4 R;  3G71 R;  3I56 R;  1NJI S;  1YIJ R;  1BXE A;  1Q81 S;  4IOA P;  1YJN R;  3CCQ R;  4IOC P;  1VQ5 R;  1VQ7 R;  1M1K S;  1VQ8 R;  3CD6 R;  4WFN P;  1QVG Q;  3CC4 R;  3CCR R;  2ZJP P;  1VQK R;  4WFA P;  3CCL R;  2ZJQ P;  2ZJR P;  1YI2 R;  5DM7 P;  1VQM R;  1VQ9 R;  1QVF Q;  5H1S U;  3CMA R;  5GAE T;  1Q82 S;  5JVG P;  5HL7 P;  3CCU R;  3DLL P;  5GAG T;  3OW2 Q;  1VQL R;  4WF9 P;  1I4J A;  5JVH P;  1YIT R;  4WFB P;  3CCJ R;  3CCE R;  1VQP R;  1VQN R;  1W2B Q;  5GAH T;  3CPW Q;  1Q7Y S;  2OTJ R;  2OTL R;  3G6E R;  1KC8 S;  1Q86 S;  4V19 W;  3PIO P;  1M90 S;  3J7Y T;  5GAD T;  4U67 P;  3PIP P;  2QEX R;  1VQ6 R;  3J7Z S;  3CC2 R;  4WCE P;  3CF5 P;  1S72 R;  3I55 R;  3CME R;  1K9M S; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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