3DLLP

The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect trna positioning
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
127
structure length
127
Chain Sequence
FRNKKQRKQQVKLRKPGFAVAKYVRMSPRKVRLVVDVIRGKSVQDAEDLLRFIPRSASEPVAKVLNSAKANALHNDEMLEDRLFVKEAYVDAGPTLKRLIPRARGSANIIKKRTSHITIIVAEKGNK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
pubmed doi rcsb
molecule tags Ribosome
molecule keywords rRNA-23S ribosomal RNA
total genus 20
structure length 127
sequence length 127
ec nomenclature
pdb deposition date 2008-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
P PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 3dllP00
5GADT 1M1KS 5HL7P 1K9MS 4IOCP 2OTJR 5GAHT 1VQPR 1JJ2Q 3CMAR 3PIPP 5JVGP 1VQLR 5H1SU 1K8AS 3J7YT 3DLLP 1KQSQ 1QVFQ 4U67P 2ZJPP 4V19W 1YJ9R 3G4SR 4WFNP 3CCLR 1VQ5R 4WF9P 2ZJQP 5DM7P 1VQNR 1VQ4R 1VQ9R 4IO9P 4IOAP 3CC4R 5DM6P 2OTLR 1VQKR 3CPWQ 3G6ER 1W2BQ 1Q82S 1VQ6R 3CD6R 1I4JA 3CCRR 3CCVR 3CMER 3CXCQ 1KD1S 3CCSR 5JVHP 1K73S 1YITR 1YJNR 1Q7YS 1VQ7R 3OW2Q 1VQMR 3G71R 3I56R 1BXEA 5GAET 4WFBP 1VQOR 4WCEP 3J7ZS 1YJWR 3CF5P 1YIJR 1YHQR 1Q86S 4UY8S 5GAGT 3CCMR 1Q81S 3CCER 5MLCU 4WFAP 2ZJRP 1QVGQ 1S72R 2QA4R 3I55R 3CC2R 3PIOP 3CC7R 1VQ8R 3CCJR 1KC8S 1M90S 1NJIS 1N8RS 3CCUR 2QEXR 3CCQR 1YI2R
chains in the Genus database with same CATH superfamily
5GADT 1M1KS 2WATA 2WDSA 5HL7P 1K9MS 4IOCP 2OTJR 5GAHT 3QMNA 1VQPR 3HYKA 1JJ2Q 2JBZA 4HC6A 3CMAR 2JCAA 3NE3B 3PIPP 5JVGP 1VQLR 5H1SU 1K8AS 3J7YT 3DLLP 1KQSQ 1QVFQ 4JM7A 4U67P 5CXDA 2ZJPP 4V19W 1YJ9R 3HQJA 3G4SR 3NE9A 5CMOA 4WFNP 3CCLR 1VQ5R 4WF9P 2ZJQP 5DM7P 1VQNR 1VQ4R 2BDDA 1VQ9R 4IO9P 4IOAP 3CC4R 5DM6P 2OTLR 1VQKR 3CPWQ 1QR0A 3G6ER 1W2BQ 1Q82S 1VQ6R 3CD6R 1I4JA 2WASA 3NE1A 3CCRR 3CCVR 3CMER 3CXCQ 1KD1S 3CCSR 5JVHP 4MRTA 3NFDA 4DXEA 1K73S 1YITR 1YI2R 1YJNR 1Q7YS 1VQ7R 1F7LA 3OW2Q 2D0OA 1VQMR 3GWMA 3G71R 3I56R 1BXEA 1FTHA 5GAET 4WFBP 1VQOR 4WCEP 3J7ZS 1YJWR 2WDOA 3CF5P 1YHQR 1YIJR 1Q86S 4UY8S 5GAGT 3CCMR 1FTFA 2CG5A 1Q81S 3CCER 5MLCU 4WFAP 2ZJRP 1QVGQ 1S72R 2QA4R 2WASB 3I55R 3CC2R 3PIOP 2C43A 3CC7R 1VQ8R 3CCJR 1KC8S 2WDYA 1F80A 3H7QA 1M90S 1NJIS 2D0PA 1N8RS 1FTEA 1NBWA 3CCUR 2QG8A 2QEXR 2BYDA 3CCQR 1F7TA
chains in the Genus database with same CATH topology
5GADT 1M1KS 5HL7P 1K9MS 4IOCP 2OTJR 5GAHT 1VQPR 1JJ2Q 3CMAR 3PIPP 5JVGP 1VQLR 5H1SU 1K8AS 3J7YT 3DLLP 1KQSQ 1QVFQ 4U67P 2ZJPP 4V19W 1YJ9R 3G4SR 4WFNP 3CCLR 1VQ5R 4WF9P 2ZJQP 5DM7P 1VQNR 1VQ4R 1VQ9R 4IO9P 4IOAP 3CC4R 5DM6P 2OTLR 1VQKR 3CPWQ 3G6ER 1W2BQ 1Q82S 1VQ6R 3CD6R 1I4JA 3CCRR 3CCVR 3CMER 3CXCQ 1KD1S 3CCSR 5JVHP 1K73S 1YITR 1YJNR 1Q7YS 1VQ7R 3OW2Q 1VQMR 3G71R 3I56R 1BXEA 5GAET 4WFBP 1VQOR 4WCEP 3J7ZS 1YJWR 3CF5P 1YIJR 1YHQR 1Q86S 4UY8S 5GAGT 3CCMR 1Q81S 3CCER 5MLCU 4WFAP 2ZJRP 1QVGQ 1S72R 2QA4R 3I55R 3CC2R 3PIOP 3CC7R 1VQ8R 3CCJR 1KC8S 1M90S 1NJIS 1N8RS 3CCUR 2QEXR 3CCQR 1YI2R
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GAD T;  1M1K S;  5HL7 P;  1K9M S;  4IOC P;  2OTJ R;  5GAH T;  1VQP R;  1JJ2 Q;  3CMA R;  3PIP P;  5JVG P;  1VQL R;  5H1S U;  1K8A S;  3J7Y T;  3DLL P;  1KQS Q;  1QVF Q;  4U67 P;  2ZJP P;  4V19 W;  1YJ9 R;  3G4S R;  4WFN P;  3CCL R;  1VQ5 R;  4WF9 P;  2ZJQ P;  5DM7 P;  1VQN R;  1VQ4 R;  1VQ9 R;  4IO9 P;  4IOA P;  3CC4 R;  5DM6 P;  2OTL R;  1VQK R;  3CPW Q;  3G6E R;  1W2B Q;  1Q82 S;  1VQ6 R;  3CD6 R;  1I4J A;  3CCR R;  3CCV R;  3CME R;  3CXC Q;  1KD1 S;  3CCS R;  5JVH P;  1K73 S;  1YIT R;  1YJN R;  1Q7Y S;  1VQ7 R;  3OW2 Q;  1VQM R;  3G71 R;  3I56 R;  1BXE A;  5GAE T;  4WFB P;  1VQO R;  4WCE P;  3J7Z S;  1YJW R;  3CF5 P;  1YIJ R;  1YHQ R;  1Q86 S;  4UY8 S;  5GAG T;  3CCM R;  1Q81 S;  3CCE R;  5MLC U;  4WFA P;  2ZJR P;  1QVG Q;  1S72 R;  2QA4 R;  3I55 R;  3CC2 R;  3PIO P;  3CC7 R;  1VQ8 R;  3CCJ R;  1KC8 S;  1M90 S;  1NJI S;  1N8R S;  3CCU R;  2QEX R;  3CCQ R;  1YI2 R; 
#chains in the Genus database with same CATH topology
 5GAD T;  1M1K S;  2WAT A;  2WDS A;  5HL7 P;  1K9M S;  4IOC P;  2OTJ R;  5GAH T;  3QMN A;  1VQP R;  3HYK A;  1JJ2 Q;  2JBZ A;  4HC6 A;  3CMA R;  2JCA A;  3NE3 B;  3PIP P;  5JVG P;  1VQL R;  5H1S U;  1K8A S;  3J7Y T;  3DLL P;  1KQS Q;  1QVF Q;  4JM7 A;  4U67 P;  5CXD A;  2ZJP P;  4V19 W;  1YJ9 R;  3HQJ A;  3G4S R;  3NE9 A;  5CMO A;  4WFN P;  3CCL R;  1VQ5 R;  4WF9 P;  2ZJQ P;  5DM7 P;  1VQN R;  1VQ4 R;  2BDD A;  1VQ9 R;  4IO9 P;  4IOA P;  3CC4 R;  5DM6 P;  2OTL R;  1VQK R;  3CPW Q;  1QR0 A;  3G6E R;  1W2B Q;  1Q82 S;  1VQ6 R;  3CD6 R;  1I4J A;  2WAS A;  3NE1 A;  3CCR R;  3CCV R;  3CME R;  3CXC Q;  1KD1 S;  3CCS R;  5JVH P;  4MRT A;  3NFD A;  4DXE A;  1K73 S;  1YIT R;  1YI2 R;  1YJN R;  1Q7Y S;  1VQ7 R;  1F7L A;  3OW2 Q;  2D0O A;  1VQM R;  3GWM A;  3G71 R;  3I56 R;  1BXE A;  1FTH A;  5GAE T;  4WFB P;  1VQO R;  4WCE P;  3J7Z S;  1YJW R;  2WDO A;  3CF5 P;  1YHQ R;  1YIJ R;  1Q86 S;  4UY8 S;  5GAG T;  3CCM R;  1FTF A;  2CG5 A;  1Q81 S;  3CCE R;  5MLC U;  4WFA P;  2ZJR P;  1QVG Q;  1S72 R;  2QA4 R;  2WAS B;  3I55 R;  3CC2 R;  3PIO P;  2C43 A;  3CC7 R;  1VQ8 R;  3CCJ R;  1KC8 S;  2WDY A;  1F80 A;  3H7Q A;  1M90 S;  1NJI S;  2D0P A;  1N8R S;  1FTE A;  1NBW A;  3CCU R;  2QG8 A;  2QEX R;  2BYD A;  3CCQ R;  1F7T A; 
#chains in the Genus database with same CATH homology
 5GAD T;  1M1K S;  5HL7 P;  1K9M S;  4IOC P;  2OTJ R;  5GAH T;  1VQP R;  1JJ2 Q;  3CMA R;  3PIP P;  5JVG P;  1VQL R;  5H1S U;  1K8A S;  3J7Y T;  3DLL P;  1KQS Q;  1QVF Q;  4U67 P;  2ZJP P;  4V19 W;  1YJ9 R;  3G4S R;  4WFN P;  3CCL R;  1VQ5 R;  4WF9 P;  2ZJQ P;  5DM7 P;  1VQN R;  1VQ4 R;  1VQ9 R;  4IO9 P;  4IOA P;  3CC4 R;  5DM6 P;  2OTL R;  1VQK R;  3CPW Q;  3G6E R;  1W2B Q;  1Q82 S;  1VQ6 R;  3CD6 R;  1I4J A;  3CCR R;  3CCV R;  3CME R;  3CXC Q;  1KD1 S;  3CCS R;  5JVH P;  1K73 S;  1YIT R;  1YJN R;  1Q7Y S;  1VQ7 R;  3OW2 Q;  1VQM R;  3G71 R;  3I56 R;  1BXE A;  5GAE T;  4WFB P;  1VQO R;  4WCE P;  3J7Z S;  1YJW R;  3CF5 P;  1YIJ R;  1YHQ R;  1Q86 S;  4UY8 S;  5GAG T;  3CCM R;  1Q81 S;  3CCE R;  5MLC U;  4WFA P;  2ZJR P;  1QVG Q;  1S72 R;  2QA4 R;  3I55 R;  3CC2 R;  3PIO P;  3CC7 R;  1VQ8 R;  3CCJ R;  1KC8 S;  1M90 S;  1NJI S;  1N8R S;  3CCU R;  2QEX R;  3CCQ R;  1YI2 R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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