3G71R

Co-crystal structure of bruceantin bound to the large ribosomal subunit
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
150
structure length
150
Chain Sequence
GISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 37
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2009-02-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 3g71R00
4WF9P 3CF5P 1VQ7R 3CPWQ 1I4JA 3CCVR 3CC2R 3CCSR 1Q86S 3CC4R 1VQLR 1VQPR 1M90S 3CXCQ 1VQOR 3CMER 4U67P 5MLCU 1VQ6R 1Q7YS 1K73S 1BXEA 1YI2R 3PIOP 2ZJRP 1K9MS 3G4SR 4WFBP 4IOCP 1VQ5R 4WFAP 1YJWR 5HL7P 1VQ8R 3CCUR 1Q82S 5GAHT 4UY8S 3I56R 5H1SU 1YJ9R 5DM7P 4WCEP 1YJNR 1KC8S 3CCER 1YHQR 3PIPP 1N8RS 3CC7R 1KQSQ 1S72R 2QEXR 3J7ZS 5JVHP 1W2BQ 1VQ4R 1VQKR 5GAGT 5JVGP 1NJIS 1K8AS 4WFNP 4V19W 3CCRR 1VQMR 4IO9P 2ZJQP 3DLLP 1JJ2Q 3OW2Q 4IOAP 1YIJR 3J7YT 2OTJR 3CD6R 3CMAR 1QVFQ 1KD1S 5GADT 2QA4R 1YITR 2ZJPP 1Q81S 3CCQR 1QVGQ 1VQ9R 1M1KS 3CCMR 3CCLR 1VQNR 5DM6P 3G6ER 3G71R 3CCJR 2OTLR 3I55R 5GAET
chains in the Genus database with same CATH superfamily
4WF9P 3CF5P 1VQ7R 3CPWQ 2CG5A 1I4JA 3CCVR 3CC2R 3CCSR 1Q86S 1FTFA 3CC4R 1VQLR 1F80A 1VQPR 1M90S 3CXCQ 2BDDA 1VQOR 3CMER 4U67P 5MLCU 1VQ6R 2QG8A 1Q7YS 1K73S 1BXEA 3PIOP 1FTHA 1YI2R 2ZJRP 1K9MS 3G4SR 4WFBP 4IOCP 1VQ5R 3H7QA 4WFAP 3HYKA 1YJWR 2WDSA 1NBWA 5CMOA 5HL7P 1VQ8R 3CCUR 3GWMA 2BYDA 1Q82S 5GAHT 4UY8S 3I56R 5H1SU 1YJ9R 3HQJA 5DM7P 3QMNA 4WCEP 1YJNR 1KC8S 3CCER 1YHQR 2JCAA 3PIPP 1N8RS 3NE1A 3CC7R 4HC6A 1KQSQ 2D0OA 1S72R 2QEXR 4MRTA 1FTEA 2D0PA 2WDYA 3J7ZS 5JVHP 2WDOA 1W2BQ 1F7LA 1VQ4R 5GAGT 1VQKR 5JVGP 2JBZA 1NJIS 1K8AS 2WASB 4DXEA 3NE3B 4WFNP 4V19W 3CCRR 1VQMR 4IO9P 2ZJQP 3DLLP 1JJ2Q 3OW2Q 4IOAP 2WATA 1YIJR 3J7YT 2OTJR 3CD6R 3NE9A 5CXDA 3CMAR 1QVFQ 1KD1S 5GADT 2QA4R 1YITR 2ZJPP 1Q81S 2C43A 3NFDA 3CCQR 1QVGQ 1VQ9R 2WASA 3CCMR 3CCLR 1M1KS 1F7TA 1VQNR 4JM7A 5DM6P 3G6ER 3G71R 3CCJR 2OTLR 1QR0A 3I55R 5GAET
chains in the Genus database with same CATH topology
4WF9P 3CF5P 1VQ7R 3CPWQ 1I4JA 3CCVR 3CC2R 3CCSR 1Q86S 3CC4R 1VQLR 1VQPR 1M90S 3CXCQ 1VQOR 3CMER 4U67P 5MLCU 1VQ6R 1Q7YS 1K73S 1BXEA 1YI2R 3PIOP 2ZJRP 1K9MS 3G4SR 4WFBP 4IOCP 1VQ5R 4WFAP 1YJWR 5HL7P 1VQ8R 3CCUR 1Q82S 5GAHT 4UY8S 3I56R 5H1SU 1YJ9R 5DM7P 4WCEP 1YJNR 1KC8S 3CCER 1YHQR 3PIPP 1N8RS 3CC7R 1KQSQ 1S72R 2QEXR 3J7ZS 5JVHP 1W2BQ 1VQ4R 1VQKR 5GAGT 5JVGP 1NJIS 1K8AS 4WFNP 4V19W 3CCRR 1VQMR 4IO9P 2ZJQP 3DLLP 1JJ2Q 3OW2Q 4IOAP 1YIJR 3J7YT 2OTJR 3CD6R 3CMAR 1QVFQ 1KD1S 5GADT 2QA4R 1YITR 2ZJPP 1Q81S 3CCQR 1QVGQ 1VQ9R 1M1KS 3CCMR 3CCLR 1VQNR 5DM6P 3G6ER 3G71R 3CCJR 2OTLR 3I55R 5GAET
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WF9 P;  3CF5 P;  1VQ7 R;  3CPW Q;  1I4J A;  3CCV R;  3CC2 R;  3CCS R;  1Q86 S;  3CC4 R;  1VQL R;  1VQP R;  1M90 S;  3CXC Q;  1VQO R;  3CME R;  4U67 P;  5MLC U;  1VQ6 R;  1Q7Y S;  1K73 S;  1BXE A;  1YI2 R;  3PIO P;  2ZJR P;  1K9M S;  3G4S R;  4WFB P;  4IOC P;  1VQ5 R;  4WFA P;  1YJW R;  5HL7 P;  1VQ8 R;  3CCU R;  1Q82 S;  5GAH T;  4UY8 S;  3I56 R;  5H1S U;  1YJ9 R;  5DM7 P;  4WCE P;  1YJN R;  1KC8 S;  3CCE R;  1YHQ R;  3PIP P;  1N8R S;  3CC7 R;  1KQS Q;  1S72 R;  2QEX R;  3J7Z S;  5JVH P;  1W2B Q;  1VQ4 R;  1VQK R;  5GAG T;  5JVG P;  1NJI S;  1K8A S;  4WFN P;  4V19 W;  3CCR R;  1VQM R;  4IO9 P;  2ZJQ P;  3DLL P;  1JJ2 Q;  3OW2 Q;  4IOA P;  1YIJ R;  3J7Y T;  2OTJ R;  3CD6 R;  3CMA R;  1QVF Q;  1KD1 S;  5GAD T;  2QA4 R;  1YIT R;  2ZJP P;  1Q81 S;  3CCQ R;  1QVG Q;  1VQ9 R;  1M1K S;  3CCM R;  3CCL R;  1VQN R;  5DM6 P;  3G6E R;  3G71 R;  3CCJ R;  2OTL R;  3I55 R;  5GAE T; 
#chains in the Genus database with same CATH topology
 4WF9 P;  3CF5 P;  1VQ7 R;  3CPW Q;  2CG5 A;  1I4J A;  3CCV R;  3CC2 R;  3CCS R;  1Q86 S;  1FTF A;  3CC4 R;  1VQL R;  1F80 A;  1VQP R;  1M90 S;  3CXC Q;  2BDD A;  1VQO R;  3CME R;  4U67 P;  5MLC U;  1VQ6 R;  2QG8 A;  1Q7Y S;  1K73 S;  1BXE A;  3PIO P;  1FTH A;  1YI2 R;  2ZJR P;  1K9M S;  3G4S R;  4WFB P;  4IOC P;  1VQ5 R;  3H7Q A;  4WFA P;  3HYK A;  1YJW R;  2WDS A;  1NBW A;  5CMO A;  5HL7 P;  1VQ8 R;  3CCU R;  3GWM A;  2BYD A;  1Q82 S;  5GAH T;  4UY8 S;  3I56 R;  5H1S U;  1YJ9 R;  3HQJ A;  5DM7 P;  3QMN A;  4WCE P;  1YJN R;  1KC8 S;  3CCE R;  1YHQ R;  2JCA A;  3PIP P;  1N8R S;  3NE1 A;  3CC7 R;  4HC6 A;  1KQS Q;  2D0O A;  1S72 R;  2QEX R;  4MRT A;  1FTE A;  2D0P A;  2WDY A;  3J7Z S;  5JVH P;  2WDO A;  1W2B Q;  1F7L A;  1VQ4 R;  5GAG T;  1VQK R;  5JVG P;  2JBZ A;  1NJI S;  1K8A S;  2WAS B;  4DXE A;  3NE3 B;  4WFN P;  4V19 W;  3CCR R;  1VQM R;  4IO9 P;  2ZJQ P;  3DLL P;  1JJ2 Q;  3OW2 Q;  4IOA P;  2WAT A;  1YIJ R;  3J7Y T;  2OTJ R;  3CD6 R;  3NE9 A;  5CXD A;  3CMA R;  1QVF Q;  1KD1 S;  5GAD T;  2QA4 R;  1YIT R;  2ZJP P;  1Q81 S;  2C43 A;  3NFD A;  3CCQ R;  1QVG Q;  1VQ9 R;  2WAS A;  3CCM R;  3CCL R;  1M1K S;  1F7T A;  1VQN R;  4JM7 A;  5DM6 P;  3G6E R;  3G71 R;  3CCJ R;  2OTL R;  1QR0 A;  3I55 R;  5GAE T; 
#chains in the Genus database with same CATH homology
 4WF9 P;  3CF5 P;  1VQ7 R;  3CPW Q;  1I4J A;  3CCV R;  3CC2 R;  3CCS R;  1Q86 S;  3CC4 R;  1VQL R;  1VQP R;  1M90 S;  3CXC Q;  1VQO R;  3CME R;  4U67 P;  5MLC U;  1VQ6 R;  1Q7Y S;  1K73 S;  1BXE A;  1YI2 R;  3PIO P;  2ZJR P;  1K9M S;  3G4S R;  4WFB P;  4IOC P;  1VQ5 R;  4WFA P;  1YJW R;  5HL7 P;  1VQ8 R;  3CCU R;  1Q82 S;  5GAH T;  4UY8 S;  3I56 R;  5H1S U;  1YJ9 R;  5DM7 P;  4WCE P;  1YJN R;  1KC8 S;  3CCE R;  1YHQ R;  3PIP P;  1N8R S;  3CC7 R;  1KQS Q;  1S72 R;  2QEX R;  3J7Z S;  5JVH P;  1W2B Q;  1VQ4 R;  1VQK R;  5GAG T;  5JVG P;  1NJI S;  1K8A S;  4WFN P;  4V19 W;  3CCR R;  1VQM R;  4IO9 P;  2ZJQ P;  3DLL P;  1JJ2 Q;  3OW2 Q;  4IOA P;  1YIJ R;  3J7Y T;  2OTJ R;  3CD6 R;  3CMA R;  1QVF Q;  1KD1 S;  5GAD T;  2QA4 R;  1YIT R;  2ZJP P;  1Q81 S;  3CCQ R;  1QVG Q;  1VQ9 R;  1M1K S;  3CCM R;  3CCL R;  1VQN R;  5DM6 P;  3G6E R;  3G71 R;  3CCJ R;  2OTL R;  3I55 R;  5GAE T; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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