3PIPP

Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit
Total Genus 28
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
126
structure length
126
Chain Sequence
FRNKKQRKQQVKLRKPGFAVAKYVRMSPRKVRLVVDVIRGKSVQDAEDLLRFIPRSASEPVAKVLNSAKANALHNDEMLEDRLFVKEAYVDAGPTLKRLIPRARGSANIIKKRTSHITIIVAEKGN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome/antibiotic
molecule keywords RIBOSOMAL 23S RNA
total genus 28
structure length 126
sequence length 126
ec nomenclature
pdb deposition date 2010-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
P PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 3pipP00
3CMER 1I4JA 5GAGT 1K9MS 5HL7P 5GAHT 4WFAP 4WFNP 4IOCP 2ZJPP 5MLCU 3OW2Q 3CMAR 3CCJR 4WCEP 3CCQR 1YI2R 3G6ER 3G4SR 4IOAP 1VQOR 3CC4R 1K8AS 2OTLR 3CCRR 3J7ZS 3CCER 2QA4R 1Q81S 3CD6R 3CCUR 3CCMR 4U67P 5DM7P 4WF9P 1VQNR 1N8RS 1YJNR 1VQ7R 1KQSQ 1Q86S 1QVGQ 1VQ4R 1VQ5R 3CC2R 5JVGP 1M90S 4WFBP 1Q7YS 1VQ6R 3PIOP 4IO9P 4V19W 1YHQR 1W2BQ 1NJIS 5JVHP 3CXCQ 1S72R 3I55R 1YITR 2ZJRP 1QVFQ 5H1SU 1VQ9R 2OTJR 1YJ9R 1VQ8R 3DLLP 1JJ2Q 1YJWR 3J7YT 3CF5P 3CCLR 1VQPR 1VQMR 3G71R 1KD1S 1M1KS 5DM6P 3CC7R 1YIJR 1Q82S 1BXEA 3CPWQ 4UY8S 3I56R 1K73S 5GADT 1VQLR 3CCSR 3PIPP 1VQKR 3CCVR 1KC8S 5GAET 2QEXR 2ZJQP
chains in the Genus database with same CATH superfamily
3CMER 2CG5A 1I4JA 5GAGT 1K9MS 5HL7P 4DXEA 5GAHT 4WFAP 4WFNP 2C43A 1NBWA 4IOCP 2ZJPP 5MLCU 3OW2Q 3HYKA 3CMAR 1FTHA 1QR0A 4JM7A 3CCJR 4WCEP 3CCQR 3H7QA 1YI2R 3G6ER 3G4SR 4IOAP 1VQOR 3CC4R 1K8AS 1F7LA 2OTLR 3HQJA 2WASB 3CCRR 3J7ZS 3CCER 2QA4R 1Q81S 3CD6R 3CCUR 4HC6A 3CCMR 1FTEA 2BDDA 4U67P 3QMNA 5DM7P 4WF9P 5CXDA 1VQNR 1N8RS 1YJNR 1VQ7R 1F7TA 1F80A 1KQSQ 2BYDA 1Q86S 1QVGQ 3NE9A 2JBZA 1VQ4R 1VQ5R 3CC2R 2D0PA 5JVGP 1M90S 4WFBP 4MRTA 1Q7YS 1VQ6R 3PIOP 3GWMA 4IO9P 4V19W 1YHQR 1W2BQ 1NJIS 5JVHP 2WASA 3CXCQ 1S72R 3I55R 1YITR 2ZJRP 1QVFQ 5H1SU 1VQ9R 2OTJR 1YJ9R 1VQ8R 3DLLP 1JJ2Q 2WDYA 1YJWR 3J7YT 3CF5P 3CCLR 1VQPR 1VQMR 3G71R 1KD1S 1M1KS 3NFDA 2WDOA 3NE3B 1FTFA 2JCAA 2QG8A 5DM6P 3CC7R 2WDSA 1YIJR 1Q82S 2D0OA 1BXEA 3CPWQ 4UY8S 3I56R 1K73S 5GADT 1VQLR 3CCSR 3PIPP 1VQKR 3NE1A 3CCVR 2WATA 5CMOA 1KC8S 5GAET 2QEXR 2ZJQP
chains in the Genus database with same CATH topology
3CMER 1I4JA 5GAGT 1K9MS 5HL7P 5GAHT 4WFAP 4WFNP 4IOCP 2ZJPP 5MLCU 3OW2Q 3CMAR 3CCJR 4WCEP 3CCQR 1YI2R 3G6ER 3G4SR 4IOAP 1VQOR 3CC4R 1K8AS 2OTLR 3CCRR 3J7ZS 3CCER 2QA4R 1Q81S 3CD6R 3CCUR 3CCMR 4U67P 5DM7P 4WF9P 1VQNR 1N8RS 1YJNR 1VQ7R 1KQSQ 1Q86S 1QVGQ 1VQ4R 1VQ5R 3CC2R 5JVGP 1M90S 4WFBP 1Q7YS 1VQ6R 3PIOP 4IO9P 4V19W 1YHQR 1W2BQ 1NJIS 5JVHP 3CXCQ 1S72R 3I55R 1YITR 2ZJRP 1QVFQ 5H1SU 1VQ9R 2OTJR 1YJ9R 1VQ8R 3DLLP 1JJ2Q 1YJWR 3J7YT 3CF5P 3CCLR 1VQPR 1VQMR 3G71R 1KD1S 1M1KS 5DM6P 3CC7R 1YIJR 1Q82S 1BXEA 3CPWQ 4UY8S 3I56R 1K73S 5GADT 1VQLR 3CCSR 3PIPP 1VQKR 3CCVR 1KC8S 5GAET 2QEXR 2ZJQP
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CME R;  1I4J A;  5GAG T;  1K9M S;  5HL7 P;  5GAH T;  4WFA P;  4WFN P;  4IOC P;  2ZJP P;  5MLC U;  3OW2 Q;  3CMA R;  3CCJ R;  4WCE P;  3CCQ R;  1YI2 R;  3G6E R;  3G4S R;  4IOA P;  1VQO R;  3CC4 R;  1K8A S;  2OTL R;  3CCR R;  3J7Z S;  3CCE R;  2QA4 R;  1Q81 S;  3CD6 R;  3CCU R;  3CCM R;  4U67 P;  5DM7 P;  4WF9 P;  1VQN R;  1N8R S;  1YJN R;  1VQ7 R;  1KQS Q;  1Q86 S;  1QVG Q;  1VQ4 R;  1VQ5 R;  3CC2 R;  5JVG P;  1M90 S;  4WFB P;  1Q7Y S;  1VQ6 R;  3PIO P;  4IO9 P;  4V19 W;  1YHQ R;  1W2B Q;  1NJI S;  5JVH P;  3CXC Q;  1S72 R;  3I55 R;  1YIT R;  2ZJR P;  1QVF Q;  5H1S U;  1VQ9 R;  2OTJ R;  1YJ9 R;  1VQ8 R;  3DLL P;  1JJ2 Q;  1YJW R;  3J7Y T;  3CF5 P;  3CCL R;  1VQP R;  1VQM R;  3G71 R;  1KD1 S;  1M1K S;  5DM6 P;  3CC7 R;  1YIJ R;  1Q82 S;  1BXE A;  3CPW Q;  4UY8 S;  3I56 R;  1K73 S;  5GAD T;  1VQL R;  3CCS R;  3PIP P;  1VQK R;  3CCV R;  1KC8 S;  5GAE T;  2QEX R;  2ZJQ P; 
#chains in the Genus database with same CATH topology
 3CME R;  2CG5 A;  1I4J A;  5GAG T;  1K9M S;  5HL7 P;  4DXE A;  5GAH T;  4WFA P;  4WFN P;  2C43 A;  1NBW A;  4IOC P;  2ZJP P;  5MLC U;  3OW2 Q;  3HYK A;  3CMA R;  1FTH A;  1QR0 A;  4JM7 A;  3CCJ R;  4WCE P;  3CCQ R;  3H7Q A;  1YI2 R;  3G6E R;  3G4S R;  4IOA P;  1VQO R;  3CC4 R;  1K8A S;  1F7L A;  2OTL R;  3HQJ A;  2WAS B;  3CCR R;  3J7Z S;  3CCE R;  2QA4 R;  1Q81 S;  3CD6 R;  3CCU R;  4HC6 A;  3CCM R;  1FTE A;  2BDD A;  4U67 P;  3QMN A;  5DM7 P;  4WF9 P;  5CXD A;  1VQN R;  1N8R S;  1YJN R;  1VQ7 R;  1F7T A;  1F80 A;  1KQS Q;  2BYD A;  1Q86 S;  1QVG Q;  3NE9 A;  2JBZ A;  1VQ4 R;  1VQ5 R;  3CC2 R;  2D0P A;  5JVG P;  1M90 S;  4WFB P;  4MRT A;  1Q7Y S;  1VQ6 R;  3PIO P;  3GWM A;  4IO9 P;  4V19 W;  1YHQ R;  1W2B Q;  1NJI S;  5JVH P;  2WAS A;  3CXC Q;  1S72 R;  3I55 R;  1YIT R;  2ZJR P;  1QVF Q;  5H1S U;  1VQ9 R;  2OTJ R;  1YJ9 R;  1VQ8 R;  3DLL P;  1JJ2 Q;  2WDY A;  1YJW R;  3J7Y T;  3CF5 P;  3CCL R;  1VQP R;  1VQM R;  3G71 R;  1KD1 S;  1M1K S;  3NFD A;  2WDO A;  3NE3 B;  1FTF A;  2JCA A;  2QG8 A;  5DM6 P;  3CC7 R;  2WDS A;  1YIJ R;  1Q82 S;  2D0O A;  1BXE A;  3CPW Q;  4UY8 S;  3I56 R;  1K73 S;  5GAD T;  1VQL R;  3CCS R;  3PIP P;  1VQK R;  3NE1 A;  3CCV R;  2WAT A;  5CMO A;  1KC8 S;  5GAE T;  2QEX R;  2ZJQ P; 
#chains in the Genus database with same CATH homology
 3CME R;  1I4J A;  5GAG T;  1K9M S;  5HL7 P;  5GAH T;  4WFA P;  4WFN P;  4IOC P;  2ZJP P;  5MLC U;  3OW2 Q;  3CMA R;  3CCJ R;  4WCE P;  3CCQ R;  1YI2 R;  3G6E R;  3G4S R;  4IOA P;  1VQO R;  3CC4 R;  1K8A S;  2OTL R;  3CCR R;  3J7Z S;  3CCE R;  2QA4 R;  1Q81 S;  3CD6 R;  3CCU R;  3CCM R;  4U67 P;  5DM7 P;  4WF9 P;  1VQN R;  1N8R S;  1YJN R;  1VQ7 R;  1KQS Q;  1Q86 S;  1QVG Q;  1VQ4 R;  1VQ5 R;  3CC2 R;  5JVG P;  1M90 S;  4WFB P;  1Q7Y S;  1VQ6 R;  3PIO P;  4IO9 P;  4V19 W;  1YHQ R;  1W2B Q;  1NJI S;  5JVH P;  3CXC Q;  1S72 R;  3I55 R;  1YIT R;  2ZJR P;  1QVF Q;  5H1S U;  1VQ9 R;  2OTJ R;  1YJ9 R;  1VQ8 R;  3DLL P;  1JJ2 Q;  1YJW R;  3J7Y T;  3CF5 P;  3CCL R;  1VQP R;  1VQM R;  3G71 R;  1KD1 S;  1M1K S;  5DM6 P;  3CC7 R;  1YIJ R;  1Q82 S;  1BXE A;  3CPW Q;  4UY8 S;  3I56 R;  1K73 S;  5GAD T;  1VQL R;  3CCS R;  3PIP P;  1VQK R;  3CCV R;  1KC8 S;  5GAE T;  2QEX R;  2ZJQ P; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...