4C4MA

Crystal structure of the sonic hedgehog-chondroitin-4-sulphate complex
Total Genus 46
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
153
structure length
153
Chain Sequence
LTPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHCSVKAENSV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural Insights Into Proteoglycan-Shaped Hedgehog Signaling.
pubmed doi rcsb
molecule tags Signaling protein
source organism Mus musculus
molecule keywords SONIC HEDGEHOG PROTEIN
total genus 46
structure length 153
sequence length 153
ec nomenclature
pdb deposition date 2013-09-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1380.10 Alpha Beta 2-Layer Sandwich Muramoyl-pentapeptide Carboxypeptidase; domain 2 Muramoyl-pentapeptide Carboxypeptidase; domain 2 4c4mA00
4JIDA 3D1MA 4C4NA 2VO9A 3N1MB 4F78A 2WG3A 3K7HB 1LBUA 2IBGE 3N1GA 4MPHA 3N1FA 4MUQA 4D0YA 4C4MA 4NT9A 1TZPA 3N1OA 5HNMA 2WFXA 1R44A 1VHHA 4MURA 2WFRA 2WG4A 3MXWA 4OX5A 3K7JB 4OAKA 4OX3A 3K7GB 3HO5H 2WFQA 3M1NA 4MUSA 3N1QA 3K7IB 1U10A 4MUTA 3N1RA 4OXDA 3N1PB
chains in the Genus database with same CATH superfamily
1SZ7A 4JIDA 3D1MA 4C4NA 2VO9A 3KXCA 2OSOA 3N1MB 2J3TA 4F78A 3NJCA 2BJNA 2WG3A 2C0JB 3K7HB 2J3WB 3CUED 1LBUA 2IBGE 2OSDA 3N1GA 3N1FA 4MPHA 4MUQA 4C4MA 4NT9A 4D0YA 1TZPA 3N1OA 2CFHC 5HNMA 2C0JA 2WFXA 1R44A 1VHHA 4MURA 2WFRA 2WG4A 3MXWA 4OX5A 1WC9A 1WC8A 2CFHA 2J3RB 3K7JB 4OAKA 2J3WD 4OX3A 3K7GB 3HO5H 2WFQA 3M1NA 4MUSA 3N1QA 2J3RA 3K7IB 3CUEB 3KXCC 1U10A 2PWNA 4MUTA 3N1RA 2J3TB 4OXDA 3N1PB
chains in the Genus database with same CATH topology
4JIDA 3D1MA 4C4NA 2VO9A 3N1MB 4F78A 2WG3A 3K7HB 1LBUA 2IBGE 3N1GA 4MPHA 3N1FA 4MUQA 4D0YA 4C4MA 4NT9A 1TZPA 3N1OA 5HNMA 2WFXA 1R44A 1VHHA 4MURA 2WFRA 2WG4A 3MXWA 4OX5A 3K7JB 4OAKA 4OX3A 3K7GB 3HO5H 2WFQA 3M1NA 4MUSA 3N1QA 3K7IB 1U10A 4MUTA 3N1RA 4OXDA 3N1PB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JID A;  3D1M A;  4C4N A;  2VO9 A;  3N1M B;  4F78 A;  2WG3 A;  3K7H B;  1LBU A;  2IBG E;  3N1G A;  4MPH A;  3N1F A;  4MUQ A;  4D0Y A;  4C4M A;  4NT9 A;  1TZP A;  3N1O A;  5HNM A;  2WFX A;  1R44 A;  1VHH A;  4MUR A;  2WFR A;  2WG4 A;  3MXW A;  4OX5 A;  3K7J B;  4OAK A;  4OX3 A;  3K7G B;  3HO5 H;  2WFQ A;  3M1N A;  4MUS A;  3N1Q A;  3K7I B;  1U10 A;  4MUT A;  3N1R A;  4OXD A;  3N1P B; 
#chains in the Genus database with same CATH topology
 1SZ7 A;  4JID A;  3D1M A;  4C4N A;  2VO9 A;  3KXC A;  2OSO A;  3N1M B;  2J3T A;  4F78 A;  3NJC A;  2BJN A;  2WG3 A;  2C0J B;  3K7H B;  2J3W B;  3CUE D;  1LBU A;  2IBG E;  2OSD A;  3N1G A;  3N1F A;  4MPH A;  4MUQ A;  4C4M A;  4NT9 A;  4D0Y A;  1TZP A;  3N1O A;  2CFH C;  5HNM A;  2C0J A;  2WFX A;  1R44 A;  1VHH A;  4MUR A;  2WFR A;  2WG4 A;  3MXW A;  4OX5 A;  1WC9 A;  1WC8 A;  2CFH A;  2J3R B;  3K7J B;  4OAK A;  2J3W D;  4OX3 A;  3K7G B;  3HO5 H;  2WFQ A;  3M1N A;  4MUS A;  3N1Q A;  2J3R A;  3K7I B;  3CUE B;  3KXC C;  1U10 A;  2PWN A;  4MUT A;  3N1R A;  2J3T B;  4OXD A;  3N1P B; 
#chains in the Genus database with same CATH homology
 4JID A;  3D1M A;  4C4N A;  2VO9 A;  3N1M B;  4F78 A;  2WG3 A;  3K7H B;  1LBU A;  2IBG E;  3N1G A;  4MPH A;  3N1F A;  4MUQ A;  4D0Y A;  4C4M A;  4NT9 A;  1TZP A;  3N1O A;  5HNM A;  2WFX A;  1R44 A;  1VHH A;  4MUR A;  2WFR A;  2WG4 A;  3MXW A;  4OX5 A;  3K7J B;  4OAK A;  4OX3 A;  3K7G B;  3HO5 H;  2WFQ A;  3M1N A;  4MUS A;  3N1Q A;  3K7I B;  1U10 A;  4MUT A;  3N1R A;  4OXD A;  3N1P B; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...