4IOCP

Crystal structure of compound 4f bound to large ribosomal subunit (50s) from deinococcus radiodurans
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
127
structure length
127
Chain Sequence
FRNKKQRKQQVKLRKPGFAVAKYVRMSPRKVRLVVDVIRGKSVQDAEDLLRFIPRSASEPVAKVLNSAKANALHNDEMLEDRLFVKEAYVDAGPTLKRLIPRARGSANIIKKRTSHITIIVAEKGNK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates.
pubmed doi rcsb
molecule tags Ribosome/ribosome inhibitor
molecule keywords 23S ribosomal RNA
total genus 26
structure length 127
sequence length 127
ec nomenclature
pdb deposition date 2013-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
P PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 4iocP00
1VQLR 3CCRR 4IO9P 4WFBP 3CCER 1YHQR 4UY8S 5HL7P 2ZJRP 1VQ5R 5GAET 2ZJQP 1YITR 3G71R 5JVHP 1VQ8R 4V19W 4WCEP 1VQKR 3CMER 1VQOR 5GADT 3J7ZS 1VQNR 1YI2R 3J7YT 3CD6R 3CCVR 2QA4R 1QVFQ 1KC8S 3CC7R 1M90S 1Q7YS 5DM6P 5MLCU 2QEXR 1N8RS 3DLLP 1YJ9R 1QVGQ 3CPWQ 2OTJR 4WFNP 1YIJR 1K9MS 1YJNR 3CCJR 1VQ4R 4IOCP 5DM7P 3CMAR 1VQ9R 3PIOP 3CCMR 1JJ2Q 1VQ6R 3CC2R 1K8AS 3G6ER 3I55R 1VQPR 3I56R 3CXCQ 1YJWR 1VQMR 1VQ7R 1BXEA 1S72R 5H1SU 2ZJPP 5JVGP 5GAGT 1Q82S 4U67P 1W2BQ 3CCUR 1Q86S 2OTLR 1M1KS 3CCQR 3PIPP 3CCSR 1KQSQ 3CCLR 5GAHT 3G4SR 1NJIS 3OW2Q 3CC4R 4WF9P 1K73S 1KD1S 1I4JA 4WFAP 3CF5P 1Q81S 4IOAP
chains in the Genus database with same CATH superfamily
1VQLR 3CCRR 4IO9P 2WDSA 4WFBP 3CCER 1YHQR 4UY8S 5HL7P 2ZJRP 3NFDA 3NE3B 1VQ5R 5GAET 2ZJQP 1YITR 3G71R 5JVHP 1VQ8R 4V19W 2WDYA 4JM7A 4WCEP 2BDDA 5CMOA 1VQKR 3CMER 1VQOR 5GADT 3J7ZS 1VQNR 1YI2R 3J7YT 3CD6R 2WATA 3CCVR 2QA4R 1QVFQ 1KC8S 1FTEA 3CC7R 1M90S 1Q7YS 5DM6P 5MLCU 2QEXR 1N8RS 2WASA 3DLLP 1YJ9R 1QVGQ 3CPWQ 2D0PA 2OTJR 4WFNP 1YIJR 1K9MS 1YJNR 3CCJR 2JBZA 1VQ4R 2JCAA 4IOCP 5DM7P 2QG8A 3CMAR 1VQ9R 5CXDA 3PIOP 3CCMR 1JJ2Q 1VQ6R 3CC2R 1K8AS 3G6ER 3I55R 1VQPR 3I56R 4DXEA 2C43A 3CXCQ 1YJWR 1VQMR 1VQ7R 2D0OA 1NBWA 1BXEA 1S72R 4MRTA 5H1SU 2ZJPP 5JVGP 5GAGT 3NE9A 3HQJA 1Q82S 4U67P 1W2BQ 3CCUR 1FTFA 3QMNA 1F7TA 3H7QA 1Q86S 2OTLR 1M1KS 3CCQR 3PIPP 3CCSR 1KQSQ 3CCLR 3NE1A 5GAHT 3G4SR 2BYDA 1NJIS 3GWMA 4HC6A 3OW2Q 3CC4R 4WF9P 1K73S 1KD1S 3HYKA 1F80A 1I4JA 1FTHA 4WFAP 3CF5P 1Q81S 2WDOA 2CG5A 4IOAP 1QR0A 1F7LA 2WASB
chains in the Genus database with same CATH topology
1VQLR 3CCRR 4IO9P 4WFBP 3CCER 1YHQR 4UY8S 5HL7P 2ZJRP 1VQ5R 5GAET 2ZJQP 1YITR 3G71R 5JVHP 1VQ8R 4V19W 4WCEP 1VQKR 3CMER 1VQOR 5GADT 3J7ZS 1VQNR 1YI2R 3J7YT 3CD6R 3CCVR 2QA4R 1QVFQ 1KC8S 3CC7R 1M90S 1Q7YS 5DM6P 5MLCU 2QEXR 1N8RS 3DLLP 1YJ9R 1QVGQ 3CPWQ 2OTJR 4WFNP 1YIJR 1K9MS 1YJNR 3CCJR 1VQ4R 4IOCP 5DM7P 3CMAR 1VQ9R 3PIOP 3CCMR 1JJ2Q 1VQ6R 3CC2R 1K8AS 3G6ER 3I55R 1VQPR 3I56R 3CXCQ 1YJWR 1VQMR 1VQ7R 1BXEA 1S72R 5H1SU 2ZJPP 5JVGP 5GAGT 1Q82S 4U67P 1W2BQ 3CCUR 1Q86S 2OTLR 1M1KS 3CCQR 3PIPP 3CCSR 1KQSQ 3CCLR 5GAHT 3G4SR 1NJIS 3OW2Q 3CC4R 4WF9P 1K73S 1KD1S 1I4JA 4WFAP 3CF5P 1Q81S 4IOAP
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQL R;  3CCR R;  4IO9 P;  4WFB P;  3CCE R;  1YHQ R;  4UY8 S;  5HL7 P;  2ZJR P;  1VQ5 R;  5GAE T;  2ZJQ P;  1YIT R;  3G71 R;  5JVH P;  1VQ8 R;  4V19 W;  4WCE P;  1VQK R;  3CME R;  1VQO R;  5GAD T;  3J7Z S;  1VQN R;  1YI2 R;  3J7Y T;  3CD6 R;  3CCV R;  2QA4 R;  1QVF Q;  1KC8 S;  3CC7 R;  1M90 S;  1Q7Y S;  5DM6 P;  5MLC U;  2QEX R;  1N8R S;  3DLL P;  1YJ9 R;  1QVG Q;  3CPW Q;  2OTJ R;  4WFN P;  1YIJ R;  1K9M S;  1YJN R;  3CCJ R;  1VQ4 R;  4IOC P;  5DM7 P;  3CMA R;  1VQ9 R;  3PIO P;  3CCM R;  1JJ2 Q;  1VQ6 R;  3CC2 R;  1K8A S;  3G6E R;  3I55 R;  1VQP R;  3I56 R;  3CXC Q;  1YJW R;  1VQM R;  1VQ7 R;  1BXE A;  1S72 R;  5H1S U;  2ZJP P;  5JVG P;  5GAG T;  1Q82 S;  4U67 P;  1W2B Q;  3CCU R;  1Q86 S;  2OTL R;  1M1K S;  3CCQ R;  3PIP P;  3CCS R;  1KQS Q;  3CCL R;  5GAH T;  3G4S R;  1NJI S;  3OW2 Q;  3CC4 R;  4WF9 P;  1K73 S;  1KD1 S;  1I4J A;  4WFA P;  3CF5 P;  1Q81 S;  4IOA P; 
#chains in the Genus database with same CATH topology
 1VQL R;  3CCR R;  4IO9 P;  2WDS A;  4WFB P;  3CCE R;  1YHQ R;  4UY8 S;  5HL7 P;  2ZJR P;  3NFD A;  3NE3 B;  1VQ5 R;  5GAE T;  2ZJQ P;  1YIT R;  3G71 R;  5JVH P;  1VQ8 R;  4V19 W;  2WDY A;  4JM7 A;  4WCE P;  2BDD A;  5CMO A;  1VQK R;  3CME R;  1VQO R;  5GAD T;  3J7Z S;  1VQN R;  1YI2 R;  3J7Y T;  3CD6 R;  2WAT A;  3CCV R;  2QA4 R;  1QVF Q;  1KC8 S;  1FTE A;  3CC7 R;  1M90 S;  1Q7Y S;  5DM6 P;  5MLC U;  2QEX R;  1N8R S;  2WAS A;  3DLL P;  1YJ9 R;  1QVG Q;  3CPW Q;  2D0P A;  2OTJ R;  4WFN P;  1YIJ R;  1K9M S;  1YJN R;  3CCJ R;  2JBZ A;  1VQ4 R;  2JCA A;  4IOC P;  5DM7 P;  2QG8 A;  3CMA R;  1VQ9 R;  5CXD A;  3PIO P;  3CCM R;  1JJ2 Q;  1VQ6 R;  3CC2 R;  1K8A S;  3G6E R;  3I55 R;  1VQP R;  3I56 R;  4DXE A;  2C43 A;  3CXC Q;  1YJW R;  1VQM R;  1VQ7 R;  2D0O A;  1NBW A;  1BXE A;  1S72 R;  4MRT A;  5H1S U;  2ZJP P;  5JVG P;  5GAG T;  3NE9 A;  3HQJ A;  1Q82 S;  4U67 P;  1W2B Q;  3CCU R;  1FTF A;  3QMN A;  1F7T A;  3H7Q A;  1Q86 S;  2OTL R;  1M1K S;  3CCQ R;  3PIP P;  3CCS R;  1KQS Q;  3CCL R;  3NE1 A;  5GAH T;  3G4S R;  2BYD A;  1NJI S;  3GWM A;  4HC6 A;  3OW2 Q;  3CC4 R;  4WF9 P;  1K73 S;  1KD1 S;  3HYK A;  1F80 A;  1I4J A;  1FTH A;  4WFA P;  3CF5 P;  1Q81 S;  2WDO A;  2CG5 A;  4IOA P;  1QR0 A;  1F7L A;  2WAS B; 
#chains in the Genus database with same CATH homology
 1VQL R;  3CCR R;  4IO9 P;  4WFB P;  3CCE R;  1YHQ R;  4UY8 S;  5HL7 P;  2ZJR P;  1VQ5 R;  5GAE T;  2ZJQ P;  1YIT R;  3G71 R;  5JVH P;  1VQ8 R;  4V19 W;  4WCE P;  1VQK R;  3CME R;  1VQO R;  5GAD T;  3J7Z S;  1VQN R;  1YI2 R;  3J7Y T;  3CD6 R;  3CCV R;  2QA4 R;  1QVF Q;  1KC8 S;  3CC7 R;  1M90 S;  1Q7Y S;  5DM6 P;  5MLC U;  2QEX R;  1N8R S;  3DLL P;  1YJ9 R;  1QVG Q;  3CPW Q;  2OTJ R;  4WFN P;  1YIJ R;  1K9M S;  1YJN R;  3CCJ R;  1VQ4 R;  4IOC P;  5DM7 P;  3CMA R;  1VQ9 R;  3PIO P;  3CCM R;  1JJ2 Q;  1VQ6 R;  3CC2 R;  1K8A S;  3G6E R;  3I55 R;  1VQP R;  3I56 R;  3CXC Q;  1YJW R;  1VQM R;  1VQ7 R;  1BXE A;  1S72 R;  5H1S U;  2ZJP P;  5JVG P;  5GAG T;  1Q82 S;  4U67 P;  1W2B Q;  3CCU R;  1Q86 S;  2OTL R;  1M1K S;  3CCQ R;  3PIP P;  3CCS R;  1KQS Q;  3CCL R;  5GAH T;  3G4S R;  1NJI S;  3OW2 Q;  3CC4 R;  4WF9 P;  1K73 S;  1KD1 S;  1I4J A;  4WFA P;  3CF5 P;  1Q81 S;  4IOA P; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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