4TR8A

Crystal structure of dna polymerase sliding clamp from pseudomonas aeruginosa
Total Genus 93
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
382
structure length
379
Chain Sequence
HHHHHHSSGLVPRGSHMHFTIQREALLKPLQLVAGVVETLPVLSNVLLVVEGQQLSLTGTDLEVELVGRVVLEDAAEPGEITVPARKLMDICKSLPNDVLIDIRVEEQKLLVKAGRSRFTLSTLPANDFPTVEEGPGSLNFSIAQSKLRRLIDRTSFAMAQQDVRYYLNGMLLEVNGGTLRSVATDGHRLAMCSLDAQIPSQDRHQVIVPRKGILELARLLTEQDGEVGIVLGQHHIRATTGEFTFTSKLVDGKFPDYERVLPRGGDKLVVGDRQQLREAFSRTAILSNEKYRGIRLQLSNGLLKIQANNPEQEEAEEEVQVEYNGGNLEIGFNVSYLLDVLGVIGTEQVRFILSDSNSSALVHEADNDDSAYVVMPMR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Differential Modes of Peptide Binding onto Replicative Sliding Clamps from Various Bacterial Origins.
pubmed doi rcsb
molecule tags Dna binding protein
source organism Pseudomonas aeruginosa hb15
molecule keywords DNA polymerase III subunit beta
total genus 93
structure length 379
sequence length 382
chains with identical sequence B
ec nomenclature ec 2.7.7.7: DNA-directed DNA polymerase.
pdb deposition date 2014-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00712 DNA_pol3_beta DNA polymerase III beta subunit, N-terminal domain
A PF02767 DNA_pol3_beta_2 DNA polymerase III beta subunit, central domain
A PF02768 DNA_pol3_beta_3 DNA polymerase III beta subunit, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4tr8A02
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4tr8A03
3.10.150.10 Alpha Beta Roll DNA Polymerase III; Chain A, domain 2 DNA Polymerase III, subunit A, domain 2 4tr8A01
4K3MA 4N99A 1JQJA 4TSZA 3Q4JA 1JQLA 1MMIA 3T0PA 3L0WA 4N95A 5AH4A 3RB9A 4N94A 4PNWA 3L0XA 3PGEB 4K3PA 5AH2A 5AGUA 4TR7A 4N97A 1UNNA 3D1FA 3L10A 4PNVA 3F1VA 4K3RA 4OVGA 3Q4KA 5FVEA 4MJQA 4N96A 4K3LA 4OVFA 1VPKA 2POLA 3D1GA 5AGVA 4N9AA 2AWAA 4K3OA 4S3IA 4OVHA 4K74A 3Q4LA 4K3SA 4PNUA 4MJRA 3D1EA 4K3KA 3QSBA 1OK7A 4RKIA 4MJPA 4TRTA 5FRQA 2AVTA 4TR8A 3QSBB 3PWEA 4K3QA 3BEPA 3P16A 4TR6A 2XURA 4N98A
chains in the Genus database with same CATH superfamily
4K3MA 4N99A 1JQJA 4TSZA 3Q4JA 1JQLA 1MMIA 3PGEA 3L0WA 4N95A 5AH4A 3RB9A 4N94A 3L0WB 3T0PA 4PNWA 3L0XA 3PGEB 4K3PA 5AH2A 5AGUA 3L0XB 4TR7A 4N97A 1UNNA 3D1FA 3L10A 4PNVA 3F1VA 3L10B 4K3RA 4OVGA 3Q4KA 5FVEA 4MJQA 4N96A 4K3LA 4OVFA 1VPKA 2POLA 3D1GA 5AGVA 4N9AA 2AWAA 4K3OA 4S3IA 4OVHA 4K74A 3Q4LA 4K3SA 4PNUA 4MJRA 3D1EA 4K3KA 3QSBA 1OK7A 4RKIA 4MJPA 4TRTA 5FRQA 2AVTA 4TR8A 3QSBB 3PWEA 4K3QA 3BEPA 3P16A 4TR6A 2XURA 4N98A
chains in the Genus database with same CATH topology
4K3MA 4N99A 1JQJA 4TSZA 3Q4JA 1JQLA 1MMIA 3T0PA 3L0WA 4N95A 5AH4A 3RB9A 4N94A 4PNWA 3L0XA 3PGEB 4K3PA 5AH2A 5AGUA 4TR7A 4N97A 1UNNA 3D1FA 3L10A 4PNVA 3F1VA 4K3RA 4OVGA 3Q4KA 5FVEA 4MJQA 4N96A 4K3LA 4OVFA 1VPKA 2POLA 3D1GA 5AGVA 4N9AA 2AWAA 4K3OA 4S3IA 4OVHA 4K74A 3Q4LA 4K3SA 4PNUA 4MJRA 3D1EA 4K3KA 3QSBA 1OK7A 4RKIA 4MJPA 4TRTA 5FRQA 2AVTA 4TR8A 3QSBB 3PWEA 4K3QA 3BEPA 3P16A 4TR6A 2XURA 4N98A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4K3M A;  4N99 A;  1JQJ A;  4TSZ A;  3Q4J A;  1JQL A;  1MMI A;  3T0P A;  3L0W A;  4N95 A;  5AH4 A;  3RB9 A;  4N94 A;  4PNW A;  3L0X A;  3PGE B;  4K3P A;  5AH2 A;  5AGU A;  4TR7 A;  4N97 A;  1UNN A;  3D1F A;  3L10 A;  4PNV A;  3F1V A;  4K3R A;  4OVG A;  3Q4K A;  5FVE A;  4MJQ A;  4N96 A;  4K3L A;  4OVF A;  1VPK A;  2POL A;  3D1G A;  5AGV A;  4N9A A;  2AWA A;  4K3O A;  4S3I A;  4OVH A;  4K74 A;  3Q4L A;  4K3S A;  4PNU A;  4MJR A;  3D1E A;  4K3K A;  3QSB A;  1OK7 A;  4RKI A;  4MJP A;  4TRT A;  5FRQ A;  2AVT A;  4TR8 A;  3QSB B;  3PWE A;  4K3Q A;  3BEP A;  3P16 A;  4TR6 A;  2XUR A;  4N98 A; 
#chains in the Genus database with same CATH topology
 4K3M A;  4N99 A;  1JQJ A;  4TSZ A;  3Q4J A;  1JQL A;  1MMI A;  3PGE A;  3L0W A;  4N95 A;  5AH4 A;  3RB9 A;  4N94 A;  3L0W B;  3T0P A;  4PNW A;  3L0X A;  3PGE B;  4K3P A;  5AH2 A;  5AGU A;  3L0X B;  4TR7 A;  4N97 A;  1UNN A;  3D1F A;  3L10 A;  4PNV A;  3F1V A;  3L10 B;  4K3R A;  4OVG A;  3Q4K A;  5FVE A;  4MJQ A;  4N96 A;  4K3L A;  4OVF A;  1VPK A;  2POL A;  3D1G A;  5AGV A;  4N9A A;  2AWA A;  4K3O A;  4S3I A;  4OVH A;  4K74 A;  3Q4L A;  4K3S A;  4PNU A;  4MJR A;  3D1E A;  4K3K A;  3QSB A;  1OK7 A;  4RKI A;  4MJP A;  4TRT A;  5FRQ A;  2AVT A;  4TR8 A;  3QSB B;  3PWE A;  4K3Q A;  3BEP A;  3P16 A;  4TR6 A;  2XUR A;  4N98 A; 
#chains in the Genus database with same CATH homology
 4K3M A;  4N99 A;  1JQJ A;  4TSZ A;  3Q4J A;  1JQL A;  1MMI A;  3T0P A;  3L0W A;  4N95 A;  5AH4 A;  3RB9 A;  4N94 A;  4PNW A;  3L0X A;  3PGE B;  4K3P A;  5AH2 A;  5AGU A;  4TR7 A;  4N97 A;  1UNN A;  3D1F A;  3L10 A;  4PNV A;  3F1V A;  4K3R A;  4OVG A;  3Q4K A;  5FVE A;  4MJQ A;  4N96 A;  4K3L A;  4OVF A;  1VPK A;  2POL A;  3D1G A;  5AGV A;  4N9A A;  2AWA A;  4K3O A;  4S3I A;  4OVH A;  4K74 A;  3Q4L A;  4K3S A;  4PNU A;  4MJR A;  3D1E A;  4K3K A;  3QSB A;  1OK7 A;  4RKI A;  4MJP A;  4TRT A;  5FRQ A;  2AVT A;  4TR8 A;  3QSB B;  3PWE A;  4K3Q A;  3BEP A;  3P16 A;  4TR6 A;  2XUR A;  4N98 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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