4IO9P

Crystal structure of compound 4d bound to large ribosomal subunit (50s) from deinococcus radiodurans
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
127
structure length
127
Chain Sequence
FRNKKQRKQQVKLRKPGFAVAKYVRMSPRKVRLVVDVIRGKSVQDAEDLLRFIPRSASEPVAKVLNSAKANALHNDEMLEDRLFVKEAYVDAGPTLKRLIPRARGSANIIKKRTSHITIIVAEKGNK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates.
pubmed doi rcsb
molecule tags Ribosome/ribosome inhibitor
molecule keywords 23S ribosomal RNA
total genus 31
structure length 127
sequence length 127
ec nomenclature
pdb deposition date 2013-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
P PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 4io9P00
1VQLR 5JVGP 1QVGQ 4WCEP 3CC4R 1BXEA 5H1SU 4WF9P 1VQ5R 1VQOR 3CPWQ 2ZJRP 3CCRR 1YI2R 4U67P 5MLCU 5DM7P 5GADT 1VQ8R 1Q81S 3CCVR 2QA4R 1YJNR 3CCLR 1M1KS 3DLLP 3CCSR 3CXCQ 3G71R 1VQNR 5GAGT 3PIOP 3CC2R 3PIPP 1VQMR 1YJWR 3CMER 3CCQR 3CMAR 3J7YT 1K8AS 1KD1S 1KC8S 3J7ZS 3OW2Q 1YIJR 1Q86S 5GAHT 1VQKR 4WFNP 1YITR 4IOAP 1Q7YS 4IOCP 2QEXR 1Q82S 4WFAP 1N8RS 3CCUR 3G4SR 4IO9P 2OTJR 3CC7R 3I56R 5HL7P 3CF5P 1KQSQ 2OTLR 1VQ7R 1QVFQ 3CCER 1K9MS 4V19W 2ZJPP 3I55R 1VQPR 1VQ9R 5JVHP 3G6ER 5GAET 2ZJQP 1YJ9R 1NJIS 1JJ2Q 1VQ6R 5DM6P 4WFBP 4UY8S 3CCMR 1W2BQ 1K73S 3CCJR 3CD6R 1VQ4R 1YHQR 1M90S 1I4JA 1S72R
chains in the Genus database with same CATH superfamily
2WATA 1VQLR 5JVGP 1QVGQ 4WCEP 3HQJA 3CC4R 3NE9A 1BXEA 5H1SU 4WF9P 1VQ5R 1VQOR 3CPWQ 2ZJRP 3CCRR 1YI2R 4U67P 1QR0A 5MLCU 5DM7P 5GADT 1FTFA 2BDDA 2WDYA 3HYKA 4MRTA 2D0OA 1VQ8R 3CCVR 5CMOA 1Q81S 2QA4R 1YJNR 2JCAA 3CCLR 1M1KS 2BYDA 3DLLP 3QMNA 3CCSR 3CXCQ 1F7LA 3G71R 1VQNR 5GAGT 3PIOP 3CC2R 3PIPP 2WASA 1VQMR 2WDOA 2C43A 1YJWR 3CMER 3CCQR 3CMAR 3J7YT 4JM7A 1K8AS 1KD1S 1KC8S 4HC6A 3J7ZS 3OW2Q 1YIJR 1Q86S 2D0PA 5GAHT 2WASB 1VQKR 4WFNP 1YITR 4IOAP 1Q7YS 5CXDA 4IOCP 2QEXR 1Q82S 4WFAP 1N8RS 3CCUR 3G4SR 4IO9P 2OTJR 3CC7R 3I56R 5HL7P 3CF5P 1KQSQ 2JBZA 3NE1A 2OTLR 1F7TA 1VQ7R 4DXEA 1QVFQ 3CCER 1K9MS 4V19W 2ZJPP 3NFDA 3I55R 1VQPR 1VQ9R 5JVHP 3G6ER 5GAET 2ZJQP 1YJ9R 1NJIS 1FTEA 1JJ2Q 1VQ6R 5DM6P 1FTHA 2WDSA 4WFBP 4UY8S 3CCMR 1W2BQ 3H7QA 1K73S 3CCJR 3CD6R 1VQ4R 3GWMA 2CG5A 1NBWA 1YHQR 1M90S 3NE3B 2QG8A 1I4JA 1S72R 1F80A
chains in the Genus database with same CATH topology
1VQLR 5JVGP 1QVGQ 4WCEP 3CC4R 1BXEA 5H1SU 4WF9P 1VQ5R 1VQOR 3CPWQ 2ZJRP 3CCRR 1YI2R 4U67P 5MLCU 5DM7P 5GADT 1VQ8R 1Q81S 3CCVR 2QA4R 1YJNR 3CCLR 1M1KS 3DLLP 3CCSR 3CXCQ 3G71R 1VQNR 5GAGT 3PIOP 3CC2R 3PIPP 1VQMR 1YJWR 3CMER 3CCQR 3CMAR 3J7YT 1K8AS 1KD1S 1KC8S 3J7ZS 3OW2Q 1YIJR 1Q86S 5GAHT 1VQKR 4WFNP 1YITR 4IOAP 1Q7YS 4IOCP 2QEXR 1Q82S 4WFAP 1N8RS 3CCUR 3G4SR 4IO9P 2OTJR 3CC7R 3I56R 5HL7P 3CF5P 1KQSQ 2OTLR 1VQ7R 1QVFQ 3CCER 1K9MS 4V19W 2ZJPP 3I55R 1VQPR 1VQ9R 5JVHP 3G6ER 5GAET 2ZJQP 1YJ9R 1NJIS 1JJ2Q 1VQ6R 5DM6P 4WFBP 4UY8S 3CCMR 1W2BQ 1K73S 3CCJR 3CD6R 1VQ4R 1YHQR 1M90S 1I4JA 1S72R
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQL R;  5JVG P;  1QVG Q;  4WCE P;  3CC4 R;  1BXE A;  5H1S U;  4WF9 P;  1VQ5 R;  1VQO R;  3CPW Q;  2ZJR P;  3CCR R;  1YI2 R;  4U67 P;  5MLC U;  5DM7 P;  5GAD T;  1VQ8 R;  1Q81 S;  3CCV R;  2QA4 R;  1YJN R;  3CCL R;  1M1K S;  3DLL P;  3CCS R;  3CXC Q;  3G71 R;  1VQN R;  5GAG T;  3PIO P;  3CC2 R;  3PIP P;  1VQM R;  1YJW R;  3CME R;  3CCQ R;  3CMA R;  3J7Y T;  1K8A S;  1KD1 S;  1KC8 S;  3J7Z S;  3OW2 Q;  1YIJ R;  1Q86 S;  5GAH T;  1VQK R;  4WFN P;  1YIT R;  4IOA P;  1Q7Y S;  4IOC P;  2QEX R;  1Q82 S;  4WFA P;  1N8R S;  3CCU R;  3G4S R;  4IO9 P;  2OTJ R;  3CC7 R;  3I56 R;  5HL7 P;  3CF5 P;  1KQS Q;  2OTL R;  1VQ7 R;  1QVF Q;  3CCE R;  1K9M S;  4V19 W;  2ZJP P;  3I55 R;  1VQP R;  1VQ9 R;  5JVH P;  3G6E R;  5GAE T;  2ZJQ P;  1YJ9 R;  1NJI S;  1JJ2 Q;  1VQ6 R;  5DM6 P;  4WFB P;  4UY8 S;  3CCM R;  1W2B Q;  1K73 S;  3CCJ R;  3CD6 R;  1VQ4 R;  1YHQ R;  1M90 S;  1I4J A;  1S72 R; 
#chains in the Genus database with same CATH topology
 2WAT A;  1VQL R;  5JVG P;  1QVG Q;  4WCE P;  3HQJ A;  3CC4 R;  3NE9 A;  1BXE A;  5H1S U;  4WF9 P;  1VQ5 R;  1VQO R;  3CPW Q;  2ZJR P;  3CCR R;  1YI2 R;  4U67 P;  1QR0 A;  5MLC U;  5DM7 P;  5GAD T;  1FTF A;  2BDD A;  2WDY A;  3HYK A;  4MRT A;  2D0O A;  1VQ8 R;  3CCV R;  5CMO A;  1Q81 S;  2QA4 R;  1YJN R;  2JCA A;  3CCL R;  1M1K S;  2BYD A;  3DLL P;  3QMN A;  3CCS R;  3CXC Q;  1F7L A;  3G71 R;  1VQN R;  5GAG T;  3PIO P;  3CC2 R;  3PIP P;  2WAS A;  1VQM R;  2WDO A;  2C43 A;  1YJW R;  3CME R;  3CCQ R;  3CMA R;  3J7Y T;  4JM7 A;  1K8A S;  1KD1 S;  1KC8 S;  4HC6 A;  3J7Z S;  3OW2 Q;  1YIJ R;  1Q86 S;  2D0P A;  5GAH T;  2WAS B;  1VQK R;  4WFN P;  1YIT R;  4IOA P;  1Q7Y S;  5CXD A;  4IOC P;  2QEX R;  1Q82 S;  4WFA P;  1N8R S;  3CCU R;  3G4S R;  4IO9 P;  2OTJ R;  3CC7 R;  3I56 R;  5HL7 P;  3CF5 P;  1KQS Q;  2JBZ A;  3NE1 A;  2OTL R;  1F7T A;  1VQ7 R;  4DXE A;  1QVF Q;  3CCE R;  1K9M S;  4V19 W;  2ZJP P;  3NFD A;  3I55 R;  1VQP R;  1VQ9 R;  5JVH P;  3G6E R;  5GAE T;  2ZJQ P;  1YJ9 R;  1NJI S;  1FTE A;  1JJ2 Q;  1VQ6 R;  5DM6 P;  1FTH A;  2WDS A;  4WFB P;  4UY8 S;  3CCM R;  1W2B Q;  3H7Q A;  1K73 S;  3CCJ R;  3CD6 R;  1VQ4 R;  3GWM A;  2CG5 A;  1NBW A;  1YHQ R;  1M90 S;  3NE3 B;  2QG8 A;  1I4J A;  1S72 R;  1F80 A; 
#chains in the Genus database with same CATH homology
 1VQL R;  5JVG P;  1QVG Q;  4WCE P;  3CC4 R;  1BXE A;  5H1S U;  4WF9 P;  1VQ5 R;  1VQO R;  3CPW Q;  2ZJR P;  3CCR R;  1YI2 R;  4U67 P;  5MLC U;  5DM7 P;  5GAD T;  1VQ8 R;  1Q81 S;  3CCV R;  2QA4 R;  1YJN R;  3CCL R;  1M1K S;  3DLL P;  3CCS R;  3CXC Q;  3G71 R;  1VQN R;  5GAG T;  3PIO P;  3CC2 R;  3PIP P;  1VQM R;  1YJW R;  3CME R;  3CCQ R;  3CMA R;  3J7Y T;  1K8A S;  1KD1 S;  1KC8 S;  3J7Z S;  3OW2 Q;  1YIJ R;  1Q86 S;  5GAH T;  1VQK R;  4WFN P;  1YIT R;  4IOA P;  1Q7Y S;  4IOC P;  2QEX R;  1Q82 S;  4WFA P;  1N8R S;  3CCU R;  3G4S R;  4IO9 P;  2OTJ R;  3CC7 R;  3I56 R;  5HL7 P;  3CF5 P;  1KQS Q;  2OTL R;  1VQ7 R;  1QVF Q;  3CCE R;  1K9M S;  4V19 W;  2ZJP P;  3I55 R;  1VQP R;  1VQ9 R;  5JVH P;  3G6E R;  5GAE T;  2ZJQ P;  1YJ9 R;  1NJI S;  1JJ2 Q;  1VQ6 R;  5DM6 P;  4WFB P;  4UY8 S;  3CCM R;  1W2B Q;  1K73 S;  3CCJ R;  3CD6 R;  1VQ4 R;  1YHQ R;  1M90 S;  1I4J A;  1S72 R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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