4IOAP

Crystal structure of compound 4e bound to large ribosomal subunit (50s) from deinococcus radiodurans
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
127
structure length
127
Chain Sequence
FRNKKQRKQQVKLRKPGFAVAKYVRMSPRKVRLVVDVIRGKSVQDAEDLLRFIPRSASEPVAKVLNSAKANALHNDEMLEDRLFVKEAYVDAGPTLKRLIPRARGSANIIKKRTSHITIIVAEKGNK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates.
pubmed doi rcsb
molecule tags Ribosome/ribosome inhibitor
molecule keywords 23S ribosomal RNA
total genus 29
structure length 127
sequence length 127
ec nomenclature
pdb deposition date 2013-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
P PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 4ioaP00
1K9MS 1VQKR 3J7ZS 5JVHP 1VQNR 3I56R 1W2BQ 4IOAP 1VQOR 1Q86S 3CC2R 5GADT 1M90S 1YI2R 1KC8S 3CCJR 3CC7R 5GAGT 4IOCP 4U67P 3PIPP 5H1SU 2ZJRP 2OTJR 1JJ2Q 1QVGQ 5MLCU 5HL7P 1KD1S 1Q82S 3I55R 1VQ8R 3DLLP 1BXEA 1S72R 3CCQR 1VQ6R 4V19W 5GAET 3CF5P 3CCUR 1VQ9R 4WFBP 1YIJR 4UY8S 3PIOP 3CCVR 1YJWR 5DM6P 5JVGP 3OW2Q 3CMAR 3CCSR 4WCEP 3G4SR 1YJ9R 1VQ7R 2ZJPP 4WF9P 1N8RS 1KQSQ 1NJIS 5GAHT 4IO9P 1QVFQ 3CC4R 1YJNR 1K8AS 3CCRR 3CD6R 3CMER 2QA4R 3J7YT 2ZJQP 1YHQR 4WFAP 1I4JA 1Q7YS 4WFNP 1M1KS 1YITR 1K73S 2QEXR 3G6ER 1VQ4R 2OTLR 1VQPR 3CPWQ 1VQMR 3CCLR 3CXCQ 3CCER 5DM7P 1VQ5R 3G71R 1Q81S 3CCMR 1VQLR
chains in the Genus database with same CATH superfamily
1K9MS 1VQKR 3J7ZS 5JVHP 1VQNR 3I56R 1W2BQ 4IOAP 1VQOR 1Q86S 3CC2R 5GADT 1M90S 3NE9A 1YI2R 1KC8S 3CCJR 3CC7R 5GAGT 4IOCP 3QMNA 4U67P 3PIPP 1F7LA 3H7QA 5H1SU 2ZJRP 4DXEA 1FTFA 2OTJR 1JJ2Q 3NFDA 2WDYA 1QVGQ 5MLCU 5HL7P 1KD1S 3I55R 1Q82S 3GWMA 1VQ8R 1F7TA 4MRTA 3DLLP 1BXEA 1S72R 3CCQR 1VQ6R 3NE3B 4V19W 5GAET 3CF5P 2CG5A 3CCUR 1VQ9R 2C43A 2WDSA 4WFBP 1YIJR 4UY8S 3PIOP 3CCVR 1YJWR 5DM6P 5JVGP 3OW2Q 2WASA 3CMAR 1NBWA 3CCSR 4WCEP 3G4SR 1YJ9R 1VQ7R 2ZJPP 4WF9P 4JM7A 1N8RS 2BYDA 1FTEA 1KQSQ 1NJIS 5GAHT 4IO9P 1QVFQ 3CC4R 2WATA 1YJNR 1K8AS 3CCRR 3CD6R 3CMER 2QA4R 3J7YT 2ZJQP 1YHQR 4WFAP 1I4JA 1QR0A 5CXDA 1Q7YS 2JCAA 2JBZA 4WFNP 1M1KS 1YITR 1K73S 5CMOA 4HC6A 2QEXR 2D0PA 1F80A 3G6ER 3NE1A 1VQ4R 2BDDA 2OTLR 2QG8A 2D0OA 1VQPR 3CPWQ 3HQJA 1VQMR 3HYKA 3CCLR 3CXCQ 2WASB 3CCER 5DM7P 2WDOA 1VQ5R 3G71R 1Q81S 3CCMR 1FTHA 1VQLR
chains in the Genus database with same CATH topology
1K9MS 1VQKR 3J7ZS 5JVHP 1VQNR 3I56R 1W2BQ 4IOAP 1VQOR 1Q86S 3CC2R 5GADT 1M90S 1YI2R 1KC8S 3CCJR 3CC7R 5GAGT 4IOCP 4U67P 3PIPP 5H1SU 2ZJRP 2OTJR 1JJ2Q 1QVGQ 5MLCU 5HL7P 1KD1S 1Q82S 3I55R 1VQ8R 3DLLP 1BXEA 1S72R 3CCQR 1VQ6R 4V19W 5GAET 3CF5P 3CCUR 1VQ9R 4WFBP 1YIJR 4UY8S 3PIOP 3CCVR 1YJWR 5DM6P 5JVGP 3OW2Q 3CMAR 3CCSR 4WCEP 3G4SR 1YJ9R 1VQ7R 2ZJPP 4WF9P 1N8RS 1KQSQ 1NJIS 5GAHT 4IO9P 1QVFQ 3CC4R 1YJNR 1K8AS 3CCRR 3CD6R 3CMER 2QA4R 3J7YT 2ZJQP 1YHQR 4WFAP 1I4JA 1Q7YS 4WFNP 1M1KS 1YITR 1K73S 2QEXR 3G6ER 1VQ4R 2OTLR 1VQPR 3CPWQ 1VQMR 3CCLR 3CXCQ 3CCER 5DM7P 1VQ5R 3G71R 1Q81S 3CCMR 1VQLR
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1K9M S;  1VQK R;  3J7Z S;  5JVH P;  1VQN R;  3I56 R;  1W2B Q;  4IOA P;  1VQO R;  1Q86 S;  3CC2 R;  5GAD T;  1M90 S;  1YI2 R;  1KC8 S;  3CCJ R;  3CC7 R;  5GAG T;  4IOC P;  4U67 P;  3PIP P;  5H1S U;  2ZJR P;  2OTJ R;  1JJ2 Q;  1QVG Q;  5MLC U;  5HL7 P;  1KD1 S;  1Q82 S;  3I55 R;  1VQ8 R;  3DLL P;  1BXE A;  1S72 R;  3CCQ R;  1VQ6 R;  4V19 W;  5GAE T;  3CF5 P;  3CCU R;  1VQ9 R;  4WFB P;  1YIJ R;  4UY8 S;  3PIO P;  3CCV R;  1YJW R;  5DM6 P;  5JVG P;  3OW2 Q;  3CMA R;  3CCS R;  4WCE P;  3G4S R;  1YJ9 R;  1VQ7 R;  2ZJP P;  4WF9 P;  1N8R S;  1KQS Q;  1NJI S;  5GAH T;  4IO9 P;  1QVF Q;  3CC4 R;  1YJN R;  1K8A S;  3CCR R;  3CD6 R;  3CME R;  2QA4 R;  3J7Y T;  2ZJQ P;  1YHQ R;  4WFA P;  1I4J A;  1Q7Y S;  4WFN P;  1M1K S;  1YIT R;  1K73 S;  2QEX R;  3G6E R;  1VQ4 R;  2OTL R;  1VQP R;  3CPW Q;  1VQM R;  3CCL R;  3CXC Q;  3CCE R;  5DM7 P;  1VQ5 R;  3G71 R;  1Q81 S;  3CCM R;  1VQL R; 
#chains in the Genus database with same CATH topology
 1K9M S;  1VQK R;  3J7Z S;  5JVH P;  1VQN R;  3I56 R;  1W2B Q;  4IOA P;  1VQO R;  1Q86 S;  3CC2 R;  5GAD T;  1M90 S;  3NE9 A;  1YI2 R;  1KC8 S;  3CCJ R;  3CC7 R;  5GAG T;  4IOC P;  3QMN A;  4U67 P;  3PIP P;  1F7L A;  3H7Q A;  5H1S U;  2ZJR P;  4DXE A;  1FTF A;  2OTJ R;  1JJ2 Q;  3NFD A;  2WDY A;  1QVG Q;  5MLC U;  5HL7 P;  1KD1 S;  3I55 R;  1Q82 S;  3GWM A;  1VQ8 R;  1F7T A;  4MRT A;  3DLL P;  1BXE A;  1S72 R;  3CCQ R;  1VQ6 R;  3NE3 B;  4V19 W;  5GAE T;  3CF5 P;  2CG5 A;  3CCU R;  1VQ9 R;  2C43 A;  2WDS A;  4WFB P;  1YIJ R;  4UY8 S;  3PIO P;  3CCV R;  1YJW R;  5DM6 P;  5JVG P;  3OW2 Q;  2WAS A;  3CMA R;  1NBW A;  3CCS R;  4WCE P;  3G4S R;  1YJ9 R;  1VQ7 R;  2ZJP P;  4WF9 P;  4JM7 A;  1N8R S;  2BYD A;  1FTE A;  1KQS Q;  1NJI S;  5GAH T;  4IO9 P;  1QVF Q;  3CC4 R;  2WAT A;  1YJN R;  1K8A S;  3CCR R;  3CD6 R;  3CME R;  2QA4 R;  3J7Y T;  2ZJQ P;  1YHQ R;  4WFA P;  1I4J A;  1QR0 A;  5CXD A;  1Q7Y S;  2JCA A;  2JBZ A;  4WFN P;  1M1K S;  1YIT R;  1K73 S;  5CMO A;  4HC6 A;  2QEX R;  2D0P A;  1F80 A;  3G6E R;  3NE1 A;  1VQ4 R;  2BDD A;  2OTL R;  2QG8 A;  2D0O A;  1VQP R;  3CPW Q;  3HQJ A;  1VQM R;  3HYK A;  3CCL R;  3CXC Q;  2WAS B;  3CCE R;  5DM7 P;  2WDO A;  1VQ5 R;  3G71 R;  1Q81 S;  3CCM R;  1FTH A;  1VQL R; 
#chains in the Genus database with same CATH homology
 1K9M S;  1VQK R;  3J7Z S;  5JVH P;  1VQN R;  3I56 R;  1W2B Q;  4IOA P;  1VQO R;  1Q86 S;  3CC2 R;  5GAD T;  1M90 S;  1YI2 R;  1KC8 S;  3CCJ R;  3CC7 R;  5GAG T;  4IOC P;  4U67 P;  3PIP P;  5H1S U;  2ZJR P;  2OTJ R;  1JJ2 Q;  1QVG Q;  5MLC U;  5HL7 P;  1KD1 S;  1Q82 S;  3I55 R;  1VQ8 R;  3DLL P;  1BXE A;  1S72 R;  3CCQ R;  1VQ6 R;  4V19 W;  5GAE T;  3CF5 P;  3CCU R;  1VQ9 R;  4WFB P;  1YIJ R;  4UY8 S;  3PIO P;  3CCV R;  1YJW R;  5DM6 P;  5JVG P;  3OW2 Q;  3CMA R;  3CCS R;  4WCE P;  3G4S R;  1YJ9 R;  1VQ7 R;  2ZJP P;  4WF9 P;  1N8R S;  1KQS Q;  1NJI S;  5GAH T;  4IO9 P;  1QVF Q;  3CC4 R;  1YJN R;  1K8A S;  3CCR R;  3CD6 R;  3CME R;  2QA4 R;  3J7Y T;  2ZJQ P;  1YHQ R;  4WFA P;  1I4J A;  1Q7Y S;  4WFN P;  1M1K S;  1YIT R;  1K73 S;  2QEX R;  3G6E R;  1VQ4 R;  2OTL R;  1VQP R;  3CPW Q;  1VQM R;  3CCL R;  3CXC Q;  3CCE R;  5DM7 P;  1VQ5 R;  3G71 R;  1Q81 S;  3CCM R;  1VQL R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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