4IOCP

Crystal structure of compound 4f bound to large ribosomal subunit (50s) from deinococcus radiodurans
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
127
structure length
127
Chain Sequence
FRNKKQRKQQVKLRKPGFAVAKYVRMSPRKVRLVVDVIRGKSVQDAEDLLRFIPRSASEPVAKVLNSAKANALHNDEMLEDRLFVKEAYVDAGPTLKRLIPRARGSANIIKKRTSHITIIVAEKGNK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates.
pubmed doi rcsb
molecule tags Ribosome/ribosome inhibitor
molecule keywords 23S ribosomal RNA
total genus 26
structure length 127
sequence length 127
ec nomenclature
pdb deposition date 2013-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
P PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 4iocP00
1VQLR 5GAET 2ZJQP 3CCMR 1YJ9R 2OTJR 1YITR 3CCVR 1KD1S 4U67P 4V19W 5JVHP 3CC7R 3CCRR 3CC2R 3DLLP 1K8AS 3I56R 1M90S 1KQSQ 1NJIS 1M1KS 1YHQR 1Q82S 4WF9P 2ZJPP 3PIPP 3G6ER 1KC8S 1K9MS 5GADT 5HL7P 3G71R 1VQ8R 1Q81S 3J7YT 5H1SU 3J7ZS 1S72R 1VQOR 5JVGP 3I55R 3CXCQ 1VQMR 4WFNP 3CCUR 1I4JA 4WCEP 1YJNR 3CF5P 1VQNR 5DM6P 4IOAP 1BXEA 5GAHT 3CCJR 2ZJRP 4IOCP 4UY8S 1YJWR 1VQ9R 1VQ4R 3CCQR 3OW2Q 4IO9P 2OTLR 5GAGT 3CMER 5DM7P 3CMAR 1YI2R 1Q86S 4WFAP 1JJ2Q 1W2BQ 1VQ6R 1VQ7R 3CCLR 3CCER 1YIJR 1VQPR 1N8RS 2QEXR 3CD6R 4WFBP 1VQKR 5MLCU 1Q7YS 1VQ5R 3CPWQ 1QVFQ 2QA4R 3CCSR 1QVGQ 1K73S 3CC4R 3G4SR 3PIOP
chains in the Genus database with same CATH superfamily
1VQLR 5GAET 2ZJQP 3CCMR 1F7TA 1YJ9R 2OTJR 1YITR 1F80A 3CCVR 2C43A 1KD1S 4U67P 4V19W 5CMOA 5JVHP 3GWMA 3CC7R 3CCRR 3CC2R 3DLLP 1K8AS 3I56R 1M90S 2WDOA 1KQSQ 1NJIS 1M1KS 1YHQR 4JM7A 1FTEA 1Q82S 4WF9P 2D0OA 2WASB 2ZJPP 3NE1A 2WDSA 2QG8A 3PIPP 3G6ER 1KC8S 1K9MS 5GADT 5HL7P 3G71R 1VQ8R 1Q81S 3J7YT 5H1SU 4HC6A 3J7ZS 1S72R 1VQOR 5JVGP 3I55R 3CXCQ 1VQMR 4WFNP 3CCUR 1QR0A 2BDDA 1I4JA 4WCEP 1YJNR 3CF5P 1VQNR 5DM6P 4IOAP 1BXEA 2JBZA 1FTFA 1NBWA 5GAHT 3NFDA 3CCJR 2ZJRP 4IOCP 4UY8S 1YJWR 2JCAA 1VQ9R 1VQ4R 3CCQR 3OW2Q 4IO9P 2WASA 5CXDA 2OTLR 5GAGT 3HYKA 3NE9A 3CMER 5DM7P 3CMAR 3NE3B 3QMNA 1YI2R 1Q86S 4WFAP 1JJ2Q 2WATA 1W2BQ 1VQ6R 3HQJA 1VQ7R 3CCLR 3CCER 1YIJR 1VQPR 1N8RS 2QEXR 3CD6R 1F7LA 2D0PA 4WFBP 1VQKR 5MLCU 2WDYA 1Q7YS 1VQ5R 2BYDA 3CPWQ 1QVFQ 2QA4R 2CG5A 3CCSR 1QVGQ 4MRTA 1K73S 4DXEA 1FTHA 3H7QA 3CC4R 3G4SR 3PIOP
chains in the Genus database with same CATH topology
1VQLR 5GAET 2ZJQP 3CCMR 1YJ9R 2OTJR 1YITR 3CCVR 1KD1S 4U67P 4V19W 5JVHP 3CC7R 3CCRR 3CC2R 3DLLP 1K8AS 3I56R 1M90S 1KQSQ 1NJIS 1M1KS 1YHQR 1Q82S 4WF9P 2ZJPP 3PIPP 3G6ER 1KC8S 1K9MS 5GADT 5HL7P 3G71R 1VQ8R 1Q81S 3J7YT 5H1SU 3J7ZS 1S72R 1VQOR 5JVGP 3I55R 3CXCQ 1VQMR 4WFNP 3CCUR 1I4JA 4WCEP 1YJNR 3CF5P 1VQNR 5DM6P 4IOAP 1BXEA 5GAHT 3CCJR 2ZJRP 4IOCP 4UY8S 1YJWR 1VQ9R 1VQ4R 3CCQR 3OW2Q 4IO9P 2OTLR 5GAGT 3CMER 5DM7P 3CMAR 1YI2R 1Q86S 4WFAP 1JJ2Q 1W2BQ 1VQ6R 1VQ7R 3CCLR 3CCER 1YIJR 1VQPR 1N8RS 2QEXR 3CD6R 4WFBP 1VQKR 5MLCU 1Q7YS 1VQ5R 3CPWQ 1QVFQ 2QA4R 3CCSR 1QVGQ 1K73S 3CC4R 3G4SR 3PIOP
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQL R;  5GAE T;  2ZJQ P;  3CCM R;  1YJ9 R;  2OTJ R;  1YIT R;  3CCV R;  1KD1 S;  4U67 P;  4V19 W;  5JVH P;  3CC7 R;  3CCR R;  3CC2 R;  3DLL P;  1K8A S;  3I56 R;  1M90 S;  1KQS Q;  1NJI S;  1M1K S;  1YHQ R;  1Q82 S;  4WF9 P;  2ZJP P;  3PIP P;  3G6E R;  1KC8 S;  1K9M S;  5GAD T;  5HL7 P;  3G71 R;  1VQ8 R;  1Q81 S;  3J7Y T;  5H1S U;  3J7Z S;  1S72 R;  1VQO R;  5JVG P;  3I55 R;  3CXC Q;  1VQM R;  4WFN P;  3CCU R;  1I4J A;  4WCE P;  1YJN R;  3CF5 P;  1VQN R;  5DM6 P;  4IOA P;  1BXE A;  5GAH T;  3CCJ R;  2ZJR P;  4IOC P;  4UY8 S;  1YJW R;  1VQ9 R;  1VQ4 R;  3CCQ R;  3OW2 Q;  4IO9 P;  2OTL R;  5GAG T;  3CME R;  5DM7 P;  3CMA R;  1YI2 R;  1Q86 S;  4WFA P;  1JJ2 Q;  1W2B Q;  1VQ6 R;  1VQ7 R;  3CCL R;  3CCE R;  1YIJ R;  1VQP R;  1N8R S;  2QEX R;  3CD6 R;  4WFB P;  1VQK R;  5MLC U;  1Q7Y S;  1VQ5 R;  3CPW Q;  1QVF Q;  2QA4 R;  3CCS R;  1QVG Q;  1K73 S;  3CC4 R;  3G4S R;  3PIO P; 
#chains in the Genus database with same CATH topology
 1VQL R;  5GAE T;  2ZJQ P;  3CCM R;  1F7T A;  1YJ9 R;  2OTJ R;  1YIT R;  1F80 A;  3CCV R;  2C43 A;  1KD1 S;  4U67 P;  4V19 W;  5CMO A;  5JVH P;  3GWM A;  3CC7 R;  3CCR R;  3CC2 R;  3DLL P;  1K8A S;  3I56 R;  1M90 S;  2WDO A;  1KQS Q;  1NJI S;  1M1K S;  1YHQ R;  4JM7 A;  1FTE A;  1Q82 S;  4WF9 P;  2D0O A;  2WAS B;  2ZJP P;  3NE1 A;  2WDS A;  2QG8 A;  3PIP P;  3G6E R;  1KC8 S;  1K9M S;  5GAD T;  5HL7 P;  3G71 R;  1VQ8 R;  1Q81 S;  3J7Y T;  5H1S U;  4HC6 A;  3J7Z S;  1S72 R;  1VQO R;  5JVG P;  3I55 R;  3CXC Q;  1VQM R;  4WFN P;  3CCU R;  1QR0 A;  2BDD A;  1I4J A;  4WCE P;  1YJN R;  3CF5 P;  1VQN R;  5DM6 P;  4IOA P;  1BXE A;  2JBZ A;  1FTF A;  1NBW A;  5GAH T;  3NFD A;  3CCJ R;  2ZJR P;  4IOC P;  4UY8 S;  1YJW R;  2JCA A;  1VQ9 R;  1VQ4 R;  3CCQ R;  3OW2 Q;  4IO9 P;  2WAS A;  5CXD A;  2OTL R;  5GAG T;  3HYK A;  3NE9 A;  3CME R;  5DM7 P;  3CMA R;  3NE3 B;  3QMN A;  1YI2 R;  1Q86 S;  4WFA P;  1JJ2 Q;  2WAT A;  1W2B Q;  1VQ6 R;  3HQJ A;  1VQ7 R;  3CCL R;  3CCE R;  1YIJ R;  1VQP R;  1N8R S;  2QEX R;  3CD6 R;  1F7L A;  2D0P A;  4WFB P;  1VQK R;  5MLC U;  2WDY A;  1Q7Y S;  1VQ5 R;  2BYD A;  3CPW Q;  1QVF Q;  2QA4 R;  2CG5 A;  3CCS R;  1QVG Q;  4MRT A;  1K73 S;  4DXE A;  1FTH A;  3H7Q A;  3CC4 R;  3G4S R;  3PIO P; 
#chains in the Genus database with same CATH homology
 1VQL R;  5GAE T;  2ZJQ P;  3CCM R;  1YJ9 R;  2OTJ R;  1YIT R;  3CCV R;  1KD1 S;  4U67 P;  4V19 W;  5JVH P;  3CC7 R;  3CCR R;  3CC2 R;  3DLL P;  1K8A S;  3I56 R;  1M90 S;  1KQS Q;  1NJI S;  1M1K S;  1YHQ R;  1Q82 S;  4WF9 P;  2ZJP P;  3PIP P;  3G6E R;  1KC8 S;  1K9M S;  5GAD T;  5HL7 P;  3G71 R;  1VQ8 R;  1Q81 S;  3J7Y T;  5H1S U;  3J7Z S;  1S72 R;  1VQO R;  5JVG P;  3I55 R;  3CXC Q;  1VQM R;  4WFN P;  3CCU R;  1I4J A;  4WCE P;  1YJN R;  3CF5 P;  1VQN R;  5DM6 P;  4IOA P;  1BXE A;  5GAH T;  3CCJ R;  2ZJR P;  4IOC P;  4UY8 S;  1YJW R;  1VQ9 R;  1VQ4 R;  3CCQ R;  3OW2 Q;  4IO9 P;  2OTL R;  5GAG T;  3CME R;  5DM7 P;  3CMA R;  1YI2 R;  1Q86 S;  4WFA P;  1JJ2 Q;  1W2B Q;  1VQ6 R;  1VQ7 R;  3CCL R;  3CCE R;  1YIJ R;  1VQP R;  1N8R S;  2QEX R;  3CD6 R;  4WFB P;  1VQK R;  5MLC U;  1Q7Y S;  1VQ5 R;  3CPW Q;  1QVF Q;  2QA4 R;  3CCS R;  1QVG Q;  1K73 S;  3CC4 R;  3G4S R;  3PIO P; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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