5CTVA

Catalytic domain of lyta, the major autolysin of streptococcus pneumoniae, (c60a, h133a, c136a mutant) complexed with peptidoglycan fragment
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
176
structure length
176
Chain Sequence
ASMEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWRKDPELGFFSHIVGNGAIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDYRLYIELLRNLADEAGLPKTLDTGSLAGIKTAEYATNNQPNNHSDHVDPYPYLAKWGISREQFKHDIENGLTI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Streptococcus pneumoniae serotype 4
publication title The crystal structure of the major pneumococcal autolysin LytA in complex with a large peptidoglycan fragment reveals the pivotal role of glycans for lytic activity.
pubmed doi rcsb
molecule keywords Autolysin
total genus 65
structure length 176
sequence length 176
ec nomenclature ec 3.5.1.28: N-acetylmuramoyl-L-alanine amidase.
pdb deposition date 2015-07-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01510 Amidase_2 N-acetylmuramoyl-L-alanine amidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.80.10 Alpha Beta 3-Layer(aba) Sandwich Lysozyme-like Peptidoglycan recognition protein-like 5ctvA00
3CG9A 2AR3A 2XZ8A 1AROL 1S2JA 4GF9A 2Y28A 2RKQA 5E0BA 2CB3A 4OUGA 3HMBA 4FNNA 4X36A 4BXEA 4BJ4A 2WKXA 1OHTA 4BXDA 3O4KA 3NG4A 3NNOA 1J3GA 3D2ZA 5DWFA 3RT4A 2Y2DA 3UILA 5E0AA 3EP1A 1TWQA 2APHA 2BH7A 2Y2CA 4BOLA 4ZXMA 2EAVA 3OGXA 3QS0A 1SK4A 2L47A 2XZ4A 2Y2EA 4OPPA 4BXJA 3C2XA 1YB0A 1LBAA 2Z9NA 3QV4A 1YCKA 4OLSA 2Y2BA 4BPAA 2R2KA 1Z6IA 1SK3A 3UMQA 4KNKA 4IVVA 4Q9EA 4Q8SA 2F2LA 3CXAA 3LATA 3T39A 1SXRA 2F2LX 3USXA 3D2YA 4KNLA 3NW3A 3CORA 3RDRA 3QJ1A 2EAXA 3TRUA 4Z8IA 3UMLA 2R90A 4ORVA 3T2VA 5CTVA
chains in the Genus database with same CATH superfamily
3CG9A 2AR3A 2XZ8A 1AROL 1S2JA 4GF9A 2Y28A 2RKQA 5E0BA 2CB3A 4OUGA 3HMBA 4FNNA 4X36A 4BXEA 4BJ4A 2WKXA 1OHTA 4BXDA 3O4KA 3NG4A 3NNOA 1J3GA 3D2ZA 5DWFA 3RT4A 2Y2DA 3UILA 5E0AA 3EP1A 1TWQA 2APHA 2BH7A 2Y2CA 4BOLA 4ZXMA 2EAVA 3OGXA 3QS0A 1SK4A 2L47A 2XZ4A 2Y2EA 4OPPA 4BXJA 3C2XA 1YB0A 1LBAA 2Z9NA 3QV4A 1YCKA 4OLSA 2Y2BA 4BPAA 2R2KA 1Z6IA 1SK3A 3UMQA 4KNKA 4IVVA 4Q9EA 4Q8SA 2F2LA 3CXAA 3LATA 3T39A 1SXRA 2F2LX 3USXA 3D2YA 4KNLA 3NW3A 3CORA 3RDRA 3QJ1A 2EAXA 3TRUA 4Z8IA 3UMLA 2R90A 4ORVA 3T2VA 5CTVA
chains in the Genus database with same CATH topology
3CG9A 2AR3A 2XZ8A 1AROL 1S2JA 4GF9A 2Y28A 2RKQA 5E0BA 2CB3A 4OUGA 3HMBA 4FNNA 4X36A 4BXEA 4BJ4A 2WKXA 1OHTA 4BXDA 3O4KA 3NG4A 3NNOA 1J3GA 3D2ZA 5DWFA 3RT4A 2Y2DA 3UILA 5E0AA 3EP1A 1TWQA 2APHA 2BH7A 2Y2CA 4BOLA 4ZXMA 2EAVA 3OGXA 3QS0A 1SK4A 2L47A 2XZ4A 2Y2EA 4OPPA 4BXJA 3C2XA 1YB0A 1LBAA 2Z9NA 3QV4A 1YCKA 4OLSA 2Y2BA 4BPAA 2R2KA 1Z6IA 1SK3A 3UMQA 4KNKA 4IVVA 4Q9EA 4Q8SA 2F2LA 3CXAA 3LATA 3T39A 1SXRA 2F2LX 3USXA 3D2YA 4KNLA 3NW3A 3CORA 3RDRA 3QJ1A 2EAXA 3TRUA 4Z8IA 3UMLA 2R90A 4ORVA 3T2VA 5CTVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CG9 A;  2AR3 A;  2XZ8 A;  1ARO L;  1S2J A;  4GF9 A;  2Y28 A;  2RKQ A;  5E0B A;  2CB3 A;  4OUG A;  3HMB A;  4FNN A;  4X36 A;  4BXE A;  4BJ4 A;  2WKX A;  1OHT A;  4BXD A;  3O4K A;  3NG4 A;  3NNO A;  1J3G A;  3D2Z A;  5DWF A;  3RT4 A;  2Y2D A;  3UIL A;  5E0A A;  3EP1 A;  1TWQ A;  2APH A;  2BH7 A;  2Y2C A;  4BOL A;  4ZXM A;  2EAV A;  3OGX A;  3QS0 A;  1SK4 A;  2L47 A;  2XZ4 A;  2Y2E A;  4OPP A;  4BXJ A;  3C2X A;  1YB0 A;  1LBA A;  2Z9N A;  3QV4 A;  1YCK A;  4OLS A;  2Y2B A;  4BPA A;  2R2K A;  1Z6I A;  1SK3 A;  3UMQ A;  4KNK A;  4IVV A;  4Q9E A;  4Q8S A;  2F2L A;  3CXA A;  3LAT A;  3T39 A;  1SXR A;  2F2L X;  3USX A;  3D2Y A;  4KNL A;  3NW3 A;  3COR A;  3RDR A;  3QJ1 A;  2EAX A;  3TRU A;  4Z8I A;  3UML A;  2R90 A;  4ORV A;  3T2V A;  5CTV A; 
#chains in the Genus database with same CATH topology
 3CG9 A;  2AR3 A;  2XZ8 A;  1ARO L;  1S2J A;  4GF9 A;  2Y28 A;  2RKQ A;  5E0B A;  2CB3 A;  4OUG A;  3HMB A;  4FNN A;  4X36 A;  4BXE A;  4BJ4 A;  2WKX A;  1OHT A;  4BXD A;  3O4K A;  3NG4 A;  3NNO A;  1J3G A;  3D2Z A;  5DWF A;  3RT4 A;  2Y2D A;  3UIL A;  5E0A A;  3EP1 A;  1TWQ A;  2APH A;  2BH7 A;  2Y2C A;  4BOL A;  4ZXM A;  2EAV A;  3OGX A;  3QS0 A;  1SK4 A;  2L47 A;  2XZ4 A;  2Y2E A;  4OPP A;  4BXJ A;  3C2X A;  1YB0 A;  1LBA A;  2Z9N A;  3QV4 A;  1YCK A;  4OLS A;  2Y2B A;  4BPA A;  2R2K A;  1Z6I A;  1SK3 A;  3UMQ A;  4KNK A;  4IVV A;  4Q9E A;  4Q8S A;  2F2L A;  3CXA A;  3LAT A;  3T39 A;  1SXR A;  2F2L X;  3USX A;  3D2Y A;  4KNL A;  3NW3 A;  3COR A;  3RDR A;  3QJ1 A;  2EAX A;  3TRU A;  4Z8I A;  3UML A;  2R90 A;  4ORV A;  3T2V A;  5CTV A; 
#chains in the Genus database with same CATH homology
 3CG9 A;  2AR3 A;  2XZ8 A;  1ARO L;  1S2J A;  4GF9 A;  2Y28 A;  2RKQ A;  5E0B A;  2CB3 A;  4OUG A;  3HMB A;  4FNN A;  4X36 A;  4BXE A;  4BJ4 A;  2WKX A;  1OHT A;  4BXD A;  3O4K A;  3NG4 A;  3NNO A;  1J3G A;  3D2Z A;  5DWF A;  3RT4 A;  2Y2D A;  3UIL A;  5E0A A;  3EP1 A;  1TWQ A;  2APH A;  2BH7 A;  2Y2C A;  4BOL A;  4ZXM A;  2EAV A;  3OGX A;  3QS0 A;  1SK4 A;  2L47 A;  2XZ4 A;  2Y2E A;  4OPP A;  4BXJ A;  3C2X A;  1YB0 A;  1LBA A;  2Z9N A;  3QV4 A;  1YCK A;  4OLS A;  2Y2B A;  4BPA A;  2R2K A;  1Z6I A;  1SK3 A;  3UMQ A;  4KNK A;  4IVV A;  4Q9E A;  4Q8S A;  2F2L A;  3CXA A;  3LAT A;  3T39 A;  1SXR A;  2F2L X;  3USX A;  3D2Y A;  4KNL A;  3NW3 A;  3COR A;  3RDR A;  3QJ1 A;  2EAX A;  3TRU A;  4Z8I A;  3UML A;  2R90 A;  4ORV A;  3T2V A;  5CTV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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