5CTVA

Catalytic domain of lyta, the major autolysin of streptococcus pneumoniae, (c60a, h133a, c136a mutant) complexed with peptidoglycan fragment
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
176
structure length
176
Chain Sequence
ASMEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWRKDPELGFFSHIVGNGAIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDYRLYIELLRNLADEAGLPKTLDTGSLAGIKTAEYATNNQPNNHSDHVDPYPYLAKWGISREQFKHDIENGLTI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of the major pneumococcal autolysin LytA in complex with a large peptidoglycan fragment reveals the pivotal role of glycans for lytic activity.
pubmed doi rcsb
molecule tags Hydrolase
source organism Streptococcus pneumoniae serotype 4
molecule keywords Autolysin
total genus 65
structure length 176
sequence length 176
ec nomenclature ec 3.5.1.28: N-acetylmuramoyl-L-alanine amidase.
pdb deposition date 2015-07-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01510 Amidase_2 N-acetylmuramoyl-L-alanine amidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.80.10 Alpha Beta 3-Layer(aba) Sandwich Lysozyme-like Peptidoglycan recognition protein-like 5ctvA00
1LBAA 1YB0A 3TRUA 3UMQA 1OHTA 4IVVA 3EP1A 2EAVA 4BXJA 4X36A 4BJ4A 1AROL 3QV4A 1S2JA 2APHA 3CORA 2CB3A 2Y2CA 3T2VA 1SK3A 1J3GA 4OPPA 3LATA 2XZ4A 2F2LA 4Z8IA 2AR3A 3QJ1A 1SK4A 3NG4A 2L47A 2Y2DA 2BH7A 3OGXA 3USXA 2Y28A 2Z9NA 4FNNA 5DWFA 3T39A 3UMLA 5E0BA 4Q8SA 2Y2EA 2WKXA 3CG9A 3UILA 4Q9EA 2RKQA 2EAXA 3C2XA 1TWQA 4BOLA 1YCKA 3QS0A 4GF9A 3RDRA 2F2LX 4BPAA 5E0AA 3NNOA 1Z6IA 4OLSA 3HMBA 3D2ZA 3O4KA 4ORVA 5CTVA 4BXEA 3RT4A 4OUGA 3D2YA 2Y2BA 2R2KA 2R90A 4BXDA 4KNLA 3NW3A 1SXRA 2XZ8A 4ZXMA 4KNKA 3CXAA
chains in the Genus database with same CATH superfamily
1LBAA 1YB0A 3TRUA 3UMQA 1OHTA 4IVVA 3EP1A 2EAVA 4BXJA 4X36A 4BJ4A 1AROL 3QV4A 1S2JA 2APHA 3CORA 2CB3A 2Y2CA 3T2VA 1SK3A 1J3GA 4OPPA 3LATA 2XZ4A 2F2LA 4Z8IA 2AR3A 3QJ1A 1SK4A 3NG4A 2L47A 2Y2DA 2BH7A 3OGXA 3USXA 2Y28A 2Z9NA 4FNNA 5DWFA 3T39A 3UMLA 5E0BA 4Q8SA 2Y2EA 2WKXA 3CG9A 3UILA 4Q9EA 2RKQA 2EAXA 3C2XA 1TWQA 4BOLA 1YCKA 3QS0A 4GF9A 3RDRA 2F2LX 4BPAA 5E0AA 3NNOA 1Z6IA 4OLSA 3HMBA 3D2ZA 3O4KA 4ORVA 5CTVA 4BXEA 3RT4A 4OUGA 3D2YA 2Y2BA 2R2KA 2R90A 4BXDA 4KNLA 3NW3A 1SXRA 2XZ8A 4ZXMA 4KNKA 3CXAA
chains in the Genus database with same CATH topology
1LBAA 1YB0A 3TRUA 3UMQA 1OHTA 4IVVA 3EP1A 2EAVA 4BXJA 4X36A 4BJ4A 1AROL 3QV4A 1S2JA 2APHA 3CORA 2CB3A 2Y2CA 3T2VA 1SK3A 1J3GA 4OPPA 3LATA 2XZ4A 2F2LA 4Z8IA 2AR3A 3QJ1A 1SK4A 3NG4A 2L47A 2Y2DA 2BH7A 3OGXA 3USXA 2Y28A 2Z9NA 4FNNA 5DWFA 3T39A 3UMLA 5E0BA 4Q8SA 2Y2EA 2WKXA 3CG9A 3UILA 4Q9EA 2RKQA 2EAXA 3C2XA 1TWQA 4BOLA 1YCKA 3QS0A 4GF9A 3RDRA 2F2LX 4BPAA 5E0AA 3NNOA 1Z6IA 4OLSA 3HMBA 3D2ZA 3O4KA 4ORVA 5CTVA 4BXEA 3RT4A 4OUGA 3D2YA 2Y2BA 2R2KA 2R90A 4BXDA 4KNLA 3NW3A 1SXRA 2XZ8A 4ZXMA 4KNKA 3CXAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LBA A;  1YB0 A;  3TRU A;  3UMQ A;  1OHT A;  4IVV A;  3EP1 A;  2EAV A;  4BXJ A;  4X36 A;  4BJ4 A;  1ARO L;  3QV4 A;  1S2J A;  2APH A;  3COR A;  2CB3 A;  2Y2C A;  3T2V A;  1SK3 A;  1J3G A;  4OPP A;  3LAT A;  2XZ4 A;  2F2L A;  4Z8I A;  2AR3 A;  3QJ1 A;  1SK4 A;  3NG4 A;  2L47 A;  2Y2D A;  2BH7 A;  3OGX A;  3USX A;  2Y28 A;  2Z9N A;  4FNN A;  5DWF A;  3T39 A;  3UML A;  5E0B A;  4Q8S A;  2Y2E A;  2WKX A;  3CG9 A;  3UIL A;  4Q9E A;  2RKQ A;  2EAX A;  3C2X A;  1TWQ A;  4BOL A;  1YCK A;  3QS0 A;  4GF9 A;  3RDR A;  2F2L X;  4BPA A;  5E0A A;  3NNO A;  1Z6I A;  4OLS A;  3HMB A;  3D2Z A;  3O4K A;  4ORV A;  5CTV A;  4BXE A;  3RT4 A;  4OUG A;  3D2Y A;  2Y2B A;  2R2K A;  2R90 A;  4BXD A;  4KNL A;  3NW3 A;  1SXR A;  2XZ8 A;  4ZXM A;  4KNK A;  3CXA A; 
#chains in the Genus database with same CATH topology
 1LBA A;  1YB0 A;  3TRU A;  3UMQ A;  1OHT A;  4IVV A;  3EP1 A;  2EAV A;  4BXJ A;  4X36 A;  4BJ4 A;  1ARO L;  3QV4 A;  1S2J A;  2APH A;  3COR A;  2CB3 A;  2Y2C A;  3T2V A;  1SK3 A;  1J3G A;  4OPP A;  3LAT A;  2XZ4 A;  2F2L A;  4Z8I A;  2AR3 A;  3QJ1 A;  1SK4 A;  3NG4 A;  2L47 A;  2Y2D A;  2BH7 A;  3OGX A;  3USX A;  2Y28 A;  2Z9N A;  4FNN A;  5DWF A;  3T39 A;  3UML A;  5E0B A;  4Q8S A;  2Y2E A;  2WKX A;  3CG9 A;  3UIL A;  4Q9E A;  2RKQ A;  2EAX A;  3C2X A;  1TWQ A;  4BOL A;  1YCK A;  3QS0 A;  4GF9 A;  3RDR A;  2F2L X;  4BPA A;  5E0A A;  3NNO A;  1Z6I A;  4OLS A;  3HMB A;  3D2Z A;  3O4K A;  4ORV A;  5CTV A;  4BXE A;  3RT4 A;  4OUG A;  3D2Y A;  2Y2B A;  2R2K A;  2R90 A;  4BXD A;  4KNL A;  3NW3 A;  1SXR A;  2XZ8 A;  4ZXM A;  4KNK A;  3CXA A; 
#chains in the Genus database with same CATH homology
 1LBA A;  1YB0 A;  3TRU A;  3UMQ A;  1OHT A;  4IVV A;  3EP1 A;  2EAV A;  4BXJ A;  4X36 A;  4BJ4 A;  1ARO L;  3QV4 A;  1S2J A;  2APH A;  3COR A;  2CB3 A;  2Y2C A;  3T2V A;  1SK3 A;  1J3G A;  4OPP A;  3LAT A;  2XZ4 A;  2F2L A;  4Z8I A;  2AR3 A;  3QJ1 A;  1SK4 A;  3NG4 A;  2L47 A;  2Y2D A;  2BH7 A;  3OGX A;  3USX A;  2Y28 A;  2Z9N A;  4FNN A;  5DWF A;  3T39 A;  3UML A;  5E0B A;  4Q8S A;  2Y2E A;  2WKX A;  3CG9 A;  3UIL A;  4Q9E A;  2RKQ A;  2EAX A;  3C2X A;  1TWQ A;  4BOL A;  1YCK A;  3QS0 A;  4GF9 A;  3RDR A;  2F2L X;  4BPA A;  5E0A A;  3NNO A;  1Z6I A;  4OLS A;  3HMB A;  3D2Z A;  3O4K A;  4ORV A;  5CTV A;  4BXE A;  3RT4 A;  4OUG A;  3D2Y A;  2Y2B A;  2R2K A;  2R90 A;  4BXD A;  4KNL A;  3NW3 A;  1SXR A;  2XZ8 A;  4ZXM A;  4KNK A;  3CXA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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