5HL7P

The crystal structure of the large ribosomal subunit of staphylococcus aureus in complex with lefamulin
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
112
structure length
112
Chain Sequence
MEAKAVARTIRIAPRKVRLVLDLIRGKNAAEAIAILKLTNKASSPVIEKVLMSALANAEHNYDMNTDELVVKEAYANEGPTLKRFRPRAQGRASAINKRTSHITIVVSDGKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2
total genus 25
structure length 112
sequence length 112
ec nomenclature
pdb deposition date 2016-01-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
P PF00237 Ribosomal_L22 Ribosomal protein L22p/L17e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.470.10 Alpha Beta Alpha-Beta Complex Ribosomal Protein L22; Chain A Ribosomal protein L22/L17 5hl7P00
2QEXR 3I56R 1YHQR 4IOAP 1VQ4R 1YI2R 4V19W 3CCVR 5HL7P 3CMAR 1VQNR 1YJNR 3CCQR 3G71R 3PIPP 5JVGP 3CD6R 5GADT 3J7ZS 3CC4R 1KD1S 1M1KS 1VQOR 1VQ8R 4U67P 5GAGT 1YJ9R 3PIOP 1K8AS 3CCMR 1Q7YS 1YIJR 4WCEP 4WFNP 3CPWQ 2ZJRP 3CCER 1YITR 3CMER 1Q81S 1VQLR 3CCLR 4UY8S 2OTJR 1VQMR 1N8RS 2ZJQP 3CCSR 3G4SR 3CCRR 1Q82S 4WFBP 1NJIS 3J7YT 5DM6P 2ZJPP 1VQKR 5H1SU 4WF9P 1K9MS 1QVGQ 1VQ9R 2OTLR 5DM7P 5GAET 3DLLP 5GAHT 1KC8S 4WFAP 1KQSQ 3CF5P 1VQ6R 2QA4R 3CC7R 1JJ2Q 3CCUR 1M90S 1BXEA 1VQ7R 1S72R 1VQPR 4IO9P 4IOCP 1I4JA 5MLCU 1VQ5R 1W2BQ 1QVFQ 1K73S 1Q86S 3CXCQ 5JVHP 1YJWR 3I55R 3OW2Q 3CCJR 3CC2R 3G6ER
chains in the Genus database with same CATH superfamily
2QEXR 3I56R 1YHQR 2WDOA 2JCAA 4IOAP 1VQ4R 1YI2R 4V19W 3CCVR 5HL7P 3CMAR 1VQNR 1NBWA 1YJNR 3CCQR 3QMNA 3G71R 3PIPP 5JVGP 3CD6R 5GADT 3J7ZS 3CC4R 1F7LA 2BDDA 1KD1S 1M1KS 1VQOR 1VQ8R 2WDYA 4U67P 5GAGT 1YJ9R 3PIOP 1K8AS 3CCMR 1YIJR 1Q7YS 4WCEP 3HQJA 4WFNP 3CPWQ 2ZJRP 4MRTA 3CCER 1YITR 3CMER 1Q81S 1VQLR 3CCLR 4UY8S 1F7TA 3NE9A 2OTJR 1VQMR 3GWMA 1FTFA 1N8RS 1QR0A 2WASB 2ZJQP 3CCSR 1F80A 3G4SR 3CCRR 1Q82S 4WFBP 3J7YT 1NJIS 5DM6P 2ZJPP 1VQKR 1FTEA 5H1SU 4WF9P 1K9MS 1QVGQ 1VQ9R 2OTLR 5DM7P 5GAET 3DLLP 5GAHT 1KC8S 3NE1A 4WFAP 1KQSQ 3CF5P 1VQ6R 2QA4R 3CC7R 1JJ2Q 2C43A 3NFDA 3CCUR 1M90S 2D0OA 1BXEA 4DXEA 2CG5A 1VQ7R 2D0PA 5CMOA 2WATA 2JBZA 2BYDA 1VQPR 1S72R 4JM7A 4IO9P 4IOCP 2WASA 1I4JA 2WDSA 3NE3B 5MLCU 1VQ5R 1W2BQ 3HYKA 4HC6A 1QVFQ 1K73S 1Q86S 2QG8A 3CXCQ 5JVHP 1YJWR 3I55R 3OW2Q 3CCJR 3CC2R 3G6ER 1FTHA 3H7QA 5CXDA
chains in the Genus database with same CATH topology
2QEXR 3I56R 1YHQR 4IOAP 1VQ4R 1YI2R 4V19W 3CCVR 5HL7P 3CMAR 1VQNR 1YJNR 3CCQR 3G71R 3PIPP 5JVGP 3CD6R 5GADT 3J7ZS 3CC4R 1KD1S 1M1KS 1VQOR 1VQ8R 4U67P 5GAGT 1YJ9R 3PIOP 1K8AS 3CCMR 1Q7YS 1YIJR 4WCEP 4WFNP 3CPWQ 2ZJRP 3CCER 1YITR 3CMER 1Q81S 1VQLR 3CCLR 4UY8S 2OTJR 1VQMR 1N8RS 2ZJQP 3CCSR 3G4SR 3CCRR 1Q82S 4WFBP 1NJIS 3J7YT 5DM6P 2ZJPP 1VQKR 5H1SU 4WF9P 1K9MS 1QVGQ 1VQ9R 2OTLR 5DM7P 5GAET 3DLLP 5GAHT 1KC8S 4WFAP 1KQSQ 3CF5P 1VQ6R 2QA4R 3CC7R 1JJ2Q 3CCUR 1M90S 1BXEA 1VQ7R 1S72R 1VQPR 4IO9P 4IOCP 1I4JA 5MLCU 1VQ5R 1W2BQ 1QVFQ 1K73S 1Q86S 3CXCQ 5JVHP 1YJWR 3I55R 3OW2Q 3CCJR 3CC2R 3G6ER
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QEX R;  3I56 R;  1YHQ R;  4IOA P;  1VQ4 R;  1YI2 R;  4V19 W;  3CCV R;  5HL7 P;  3CMA R;  1VQN R;  1YJN R;  3CCQ R;  3G71 R;  3PIP P;  5JVG P;  3CD6 R;  5GAD T;  3J7Z S;  3CC4 R;  1KD1 S;  1M1K S;  1VQO R;  1VQ8 R;  4U67 P;  5GAG T;  1YJ9 R;  3PIO P;  1K8A S;  3CCM R;  1Q7Y S;  1YIJ R;  4WCE P;  4WFN P;  3CPW Q;  2ZJR P;  3CCE R;  1YIT R;  3CME R;  1Q81 S;  1VQL R;  3CCL R;  4UY8 S;  2OTJ R;  1VQM R;  1N8R S;  2ZJQ P;  3CCS R;  3G4S R;  3CCR R;  1Q82 S;  4WFB P;  1NJI S;  3J7Y T;  5DM6 P;  2ZJP P;  1VQK R;  5H1S U;  4WF9 P;  1K9M S;  1QVG Q;  1VQ9 R;  2OTL R;  5DM7 P;  5GAE T;  3DLL P;  5GAH T;  1KC8 S;  4WFA P;  1KQS Q;  3CF5 P;  1VQ6 R;  2QA4 R;  3CC7 R;  1JJ2 Q;  3CCU R;  1M90 S;  1BXE A;  1VQ7 R;  1S72 R;  1VQP R;  4IO9 P;  4IOC P;  1I4J A;  5MLC U;  1VQ5 R;  1W2B Q;  1QVF Q;  1K73 S;  1Q86 S;  3CXC Q;  5JVH P;  1YJW R;  3I55 R;  3OW2 Q;  3CCJ R;  3CC2 R;  3G6E R; 
#chains in the Genus database with same CATH topology
 2QEX R;  3I56 R;  1YHQ R;  2WDO A;  2JCA A;  4IOA P;  1VQ4 R;  1YI2 R;  4V19 W;  3CCV R;  5HL7 P;  3CMA R;  1VQN R;  1NBW A;  1YJN R;  3CCQ R;  3QMN A;  3G71 R;  3PIP P;  5JVG P;  3CD6 R;  5GAD T;  3J7Z S;  3CC4 R;  1F7L A;  2BDD A;  1KD1 S;  1M1K S;  1VQO R;  1VQ8 R;  2WDY A;  4U67 P;  5GAG T;  1YJ9 R;  3PIO P;  1K8A S;  3CCM R;  1YIJ R;  1Q7Y S;  4WCE P;  3HQJ A;  4WFN P;  3CPW Q;  2ZJR P;  4MRT A;  3CCE R;  1YIT R;  3CME R;  1Q81 S;  1VQL R;  3CCL R;  4UY8 S;  1F7T A;  3NE9 A;  2OTJ R;  1VQM R;  3GWM A;  1FTF A;  1N8R S;  1QR0 A;  2WAS B;  2ZJQ P;  3CCS R;  1F80 A;  3G4S R;  3CCR R;  1Q82 S;  4WFB P;  3J7Y T;  1NJI S;  5DM6 P;  2ZJP P;  1VQK R;  1FTE A;  5H1S U;  4WF9 P;  1K9M S;  1QVG Q;  1VQ9 R;  2OTL R;  5DM7 P;  5GAE T;  3DLL P;  5GAH T;  1KC8 S;  3NE1 A;  4WFA P;  1KQS Q;  3CF5 P;  1VQ6 R;  2QA4 R;  3CC7 R;  1JJ2 Q;  2C43 A;  3NFD A;  3CCU R;  1M90 S;  2D0O A;  1BXE A;  4DXE A;  2CG5 A;  1VQ7 R;  2D0P A;  5CMO A;  2WAT A;  2JBZ A;  2BYD A;  1VQP R;  1S72 R;  4JM7 A;  4IO9 P;  4IOC P;  2WAS A;  1I4J A;  2WDS A;  3NE3 B;  5MLC U;  1VQ5 R;  1W2B Q;  3HYK A;  4HC6 A;  1QVF Q;  1K73 S;  1Q86 S;  2QG8 A;  3CXC Q;  5JVH P;  1YJW R;  3I55 R;  3OW2 Q;  3CCJ R;  3CC2 R;  3G6E R;  1FTH A;  3H7Q A;  5CXD A; 
#chains in the Genus database with same CATH homology
 2QEX R;  3I56 R;  1YHQ R;  4IOA P;  1VQ4 R;  1YI2 R;  4V19 W;  3CCV R;  5HL7 P;  3CMA R;  1VQN R;  1YJN R;  3CCQ R;  3G71 R;  3PIP P;  5JVG P;  3CD6 R;  5GAD T;  3J7Z S;  3CC4 R;  1KD1 S;  1M1K S;  1VQO R;  1VQ8 R;  4U67 P;  5GAG T;  1YJ9 R;  3PIO P;  1K8A S;  3CCM R;  1Q7Y S;  1YIJ R;  4WCE P;  4WFN P;  3CPW Q;  2ZJR P;  3CCE R;  1YIT R;  3CME R;  1Q81 S;  1VQL R;  3CCL R;  4UY8 S;  2OTJ R;  1VQM R;  1N8R S;  2ZJQ P;  3CCS R;  3G4S R;  3CCR R;  1Q82 S;  4WFB P;  1NJI S;  3J7Y T;  5DM6 P;  2ZJP P;  1VQK R;  5H1S U;  4WF9 P;  1K9M S;  1QVG Q;  1VQ9 R;  2OTL R;  5DM7 P;  5GAE T;  3DLL P;  5GAH T;  1KC8 S;  4WFA P;  1KQS Q;  3CF5 P;  1VQ6 R;  2QA4 R;  3CC7 R;  1JJ2 Q;  3CCU R;  1M90 S;  1BXE A;  1VQ7 R;  1S72 R;  1VQP R;  4IO9 P;  4IOC P;  1I4J A;  5MLC U;  1VQ5 R;  1W2B Q;  1QVF Q;  1K73 S;  1Q86 S;  3CXC Q;  5JVH P;  1YJW R;  3I55 R;  3OW2 Q;  3CCJ R;  3CC2 R;  3G6E R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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