1BPTA

Crevice-forming mutants of bpti: crystal structures of f22a, y23a, n43g, and f45a
Total Genus 8
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
56
structure length
56
Chain Sequence
RPDFCLEPPYTGPCKARIIRYFANAKAGLCQTFVYGGCRAKRNNFKSAEDCMRTCG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crevice-forming mutants in the rigid core of bovine pancreatic trypsin inhibitor: crystal structures of F22A, Y23A, N43G, and F45A.
pubmed rcsb
molecule tags Proteinase inhibitor (trypsin)
source organism Bos taurus
molecule keywords BOVINE PANCREATIC TRYPSIN INHIBITOR
total genus 8
structure length 56
sequence length 56
ec nomenclature
pdb deposition date 1991-12-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 1bptA00
1CBWD 3BTMI 3OTJI 2UUYB 1FY8I 1TAPA 1JC6A 4U32X 2RA3C 2PTCI 1CA0D 4DTGK 3UIRC 4DG4C 1P2II 1P2QB 1LD6A 1UUAA 4PTIA 2LFLA 1SHPA 3BTQI 1TCPA 1T8OB 5PTIA 4Y0ZI 1F5RI 3FP6I 1AALA 1BZ5A 1KTHA 1K6UA 4Y0YI 2FI3I 3M7QB 3CI7A 3LDJA 1DEMA 1OA55 3WNYA 4NTXB 1JV9A 2M99A 1YC0I 2J6DA 4U30W 3AUCA 2DDIA 1TAWB 1BHCA 2ODYE 1B0CA 2LFKA 1NAGA 2KAII 1G6XA 1PITA 1EJMB 1UUBA 3GYMI 1LD5A 4NTYB 1BF0A 2CA7A 1BIKA 1MTND 1TOCR 3AUEA 3TGKI 3AUBA 1P2JI 3P95E 1OA65 2HEXA 3BTKI 1D0DB 2IJOI 1EAWB 4BNRI 2KNTA 3TGII 1CO7I 2W8XA 3P92E 3BTWI 2DDJA 3AUDA 5JB7A 1KIGI 1ZJDB 3BTEI 1YKTB 3BTHI 1IRHA 4ISOB 1DTXA 1DENA 2KCRA 5C67C 3L3TE 1KNTA 2JOTA 1P2MB 4BD9B 1BTIA 2FI5I 4WWYC 4WXVC 1P2NB 9PTIA 5JB4A 3T62D 2TGPI 1FANA 2R9PE 2TPII 1YLDB 1BZXI 7PTIA 2ZJXA 3TGJI 3FP7J 5JB5A 2FTLI 1T8MB 3L33E 3AUGA 1BTHP 3AUHA 5JB6A 2M01A 1Y62A 1YLCB 3BTTI 3BTFI 1BPTA 1T8LB 8PTIA 1DTKA 4BQDA 4Y11I 1F7ZI 1P2KI 1JV8A 1BRCI 4ISNB 1BRBI 3BTDI 1BUNB 1KUNA 2FI4I 1ADZA 1BPIA 3LDIA 6PTIA 1P2OB 3FP8I 3BYBA 4ISLB 1D0DA 3LDMA 3OFWA 3AUIA 3D65I 3TPII 1T7CB 4Y10I 3BTGI 1T8NB 1ZR0B 3UOUB 2ZVXA 2UUXA 4NTWB 1AAPA 4TPII 1FAKI 1QLQA 3U1JE 1TFXC 1TPAI 2FTMB
chains in the Genus database with same CATH superfamily
1CBWD 3BTMI 3OTJI 2UUYB 1FY8I 1TAPA 1JC6A 4U32X 2RA3C 2PTCI 1CA0D 4DTGK 3UIRC 4DG4C 1P2II 1P2QB 1LD6A 1UUAA 4PTIA 2LFLA 1SHPA 3BTQI 1TCPA 1T8OB 5PTIA 4Y0ZI 1F5RI 3FP6I 1AALA 1BZ5A 1KTHA 1K6UA 4Y0YI 2FI3I 3M7QB 3CI7A 3LDJA 1DEMA 1OA55 3WNYA 4NTXB 1JV9A 2M99A 1YC0I 2J6DA 4U30W 3AUCA 2DDIA 1TAWB 1BHCA 2ODYE 1B0CA 2LFKA 1NAGA 2KAII 1G6XA 1PITA 1EJMB 1UUBA 3GYMI 1LD5A 4NTYB 1BF0A 2CA7A 1BIKA 1MTND 1TOCR 3AUEA 3TGKI 3AUBA 1P2JI 3P95E 1OA65 2HEXA 3BTKI 1D0DB 2IJOI 1EAWB 4BNRI 2KNTA 3TGII 1CO7I 2W8XA 3P92E 3BTWI 2DDJA 3AUDA 5JB7A 1KIGI 1ZJDB 3BTEI 1YKTB 3BTHI 1IRHA 4ISOB 1DTXA 1DENA 2KCRA 5C67C 3L3TE 1KNTA 2JOTA 1P2MB 4BD9B 1BTIA 2FI5I 4WWYC 4WXVC 1P2NB 9PTIA 5JB4A 3T62D 2TGPI 1FANA 2R9PE 2TPII 1YLDB 1BZXI 7PTIA 2ZJXA 3TGJI 3FP7J 5JB5A 2FTLI 1T8MB 3L33E 3AUGA 1BTHP 3AUHA 5JB6A 2M01A 1Y62A 1YLCB 3BTTI 3BTFI 1BPTA 1T8LB 8PTIA 1DTKA 4BQDA 4Y11I 1F7ZI 1P2KI 1JV8A 1BRCI 4ISNB 1BRBI 3BTDI 1BUNB 1KUNA 2FI4I 1ADZA 1BPIA 3LDIA 6PTIA 1P2OB 3FP8I 3BYBA 4ISLB 1D0DA 3LDMA 3OFWA 3AUIA 3D65I 3TPII 1T7CB 4Y10I 3BTGI 1T8NB 1ZR0B 3UOUB 2ZVXA 2UUXA 4NTWB 1AAPA 4TPII 1FAKI 1QLQA 3U1JE 1TFXC 1TPAI 2FTMB
chains in the Genus database with same CATH topology
1CBWD 3BTMI 3OTJI 2UUYB 1FY8I 1TAPA 1JC6A 4U32X 2RA3C 2PTCI 1CA0D 4DTGK 3UIRC 4DG4C 1P2II 1P2QB 1LD6A 1UUAA 4PTIA 2LFLA 1SHPA 3BTQI 1TCPA 1T8OB 5PTIA 4Y0ZI 1F5RI 3FP6I 1AALA 1BZ5A 1KTHA 1K6UA 4Y0YI 2FI3I 3M7QB 3CI7A 3LDJA 1DEMA 1OA55 3WNYA 4NTXB 1JV9A 2M99A 1YC0I 2J6DA 4U30W 3AUCA 2DDIA 1TAWB 1BHCA 2ODYE 1B0CA 2LFKA 1NAGA 2KAII 1G6XA 1PITA 1EJMB 1UUBA 3GYMI 1LD5A 4NTYB 1BF0A 2CA7A 1BIKA 1MTND 1TOCR 3AUEA 3TGKI 3AUBA 1P2JI 3P95E 1OA65 2HEXA 3BTKI 1D0DB 2IJOI 1EAWB 4BNRI 2KNTA 3TGII 1CO7I 2W8XA 3P92E 3BTWI 2DDJA 3AUDA 5JB7A 1KIGI 1ZJDB 3BTEI 1YKTB 3BTHI 1IRHA 4ISOB 1DTXA 1DENA 2KCRA 5C67C 3L3TE 1KNTA 2JOTA 1P2MB 4BD9B 1BTIA 2FI5I 4WWYC 4WXVC 1P2NB 9PTIA 5JB4A 3T62D 2TGPI 1FANA 2R9PE 2TPII 1YLDB 1BZXI 7PTIA 2ZJXA 3TGJI 3FP7J 5JB5A 2FTLI 1T8MB 3L33E 3AUGA 1BTHP 3AUHA 5JB6A 2M01A 1Y62A 1YLCB 3BTTI 3BTFI 1BPTA 1T8LB 8PTIA 1DTKA 4BQDA 4Y11I 1F7ZI 1P2KI 1JV8A 1BRCI 4ISNB 1BRBI 3BTDI 1BUNB 1KUNA 2FI4I 1ADZA 1BPIA 3LDIA 6PTIA 1P2OB 3FP8I 3BYBA 4ISLB 1D0DA 3LDMA 3OFWA 3AUIA 3D65I 3TPII 1T7CB 4Y10I 3BTGI 1T8NB 1ZR0B 3UOUB 2ZVXA 2UUXA 4NTWB 1AAPA 4TPII 1FAKI 1QLQA 3U1JE 1TFXC 1TPAI 2FTMB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CBW D;  3BTM I;  3OTJ I;  2UUY B;  1FY8 I;  1TAP A;  1JC6 A;  4U32 X;  2RA3 C;  2PTC I;  1CA0 D;  4DTG K;  3UIR C;  4DG4 C;  1P2I I;  1P2Q B;  1LD6 A;  1UUA A;  4PTI A;  2LFL A;  1SHP A;  3BTQ I;  1TCP A;  1T8O B;  5PTI A;  4Y0Z I;  1F5R I;  3FP6 I;  1AAL A;  1BZ5 A;  1KTH A;  1K6U A;  4Y0Y I;  2FI3 I;  3M7Q B;  3CI7 A;  3LDJ A;  1DEM A;  1OA5 5;  3WNY A;  4NTX B;  1JV9 A;  2M99 A;  1YC0 I;  2J6D A;  4U30 W;  3AUC A;  2DDI A;  1TAW B;  1BHC A;  2ODY E;  1B0C A;  2LFK A;  1NAG A;  2KAI I;  1G6X A;  1PIT A;  1EJM B;  1UUB A;  3GYM I;  1LD5 A;  4NTY B;  1BF0 A;  2CA7 A;  1BIK A;  1MTN D;  1TOC R;  3AUE A;  3TGK I;  3AUB A;  1P2J I;  3P95 E;  1OA6 5;  2HEX A;  3BTK I;  1D0D B;  2IJO I;  1EAW B;  4BNR I;  2KNT A;  3TGI I;  1CO7 I;  2W8X A;  3P92 E;  3BTW I;  2DDJ A;  3AUD A;  5JB7 A;  1KIG I;  1ZJD B;  3BTE I;  1YKT B;  3BTH I;  1IRH A;  4ISO B;  1DTX A;  1DEN A;  2KCR A;  5C67 C;  3L3T E;  1KNT A;  2JOT A;  1P2M B;  4BD9 B;  1BTI A;  2FI5 I;  4WWY C;  4WXV C;  1P2N B;  9PTI A;  5JB4 A;  3T62 D;  2TGP I;  1FAN A;  2R9P E;  2TPI I;  1YLD B;  1BZX I;  7PTI A;  2ZJX A;  3TGJ I;  3FP7 J;  5JB5 A;  2FTL I;  1T8M B;  3L33 E;  3AUG A;  1BTH P;  3AUH A;  5JB6 A;  2M01 A;  1Y62 A;  1YLC B;  3BTT I;  3BTF I;  1BPT A;  1T8L B;  8PTI A;  1DTK A;  4BQD A;  4Y11 I;  1F7Z I;  1P2K I;  1JV8 A;  1BRC I;  4ISN B;  1BRB I;  3BTD I;  1BUN B;  1KUN A;  2FI4 I;  1ADZ A;  1BPI A;  3LDI A;  6PTI A;  1P2O B;  3FP8 I;  3BYB A;  4ISL B;  1D0D A;  3LDM A;  3OFW A;  3AUI A;  3D65 I;  3TPI I;  1T7C B;  4Y10 I;  3BTG I;  1T8N B;  1ZR0 B;  3UOU B;  2ZVX A;  2UUX A;  4NTW B;  1AAP A;  4TPI I;  1FAK I;  1QLQ A;  3U1J E;  1TFX C;  1TPA I;  2FTM B; 
#chains in the Genus database with same CATH topology
 1CBW D;  3BTM I;  3OTJ I;  2UUY B;  1FY8 I;  1TAP A;  1JC6 A;  4U32 X;  2RA3 C;  2PTC I;  1CA0 D;  4DTG K;  3UIR C;  4DG4 C;  1P2I I;  1P2Q B;  1LD6 A;  1UUA A;  4PTI A;  2LFL A;  1SHP A;  3BTQ I;  1TCP A;  1T8O B;  5PTI A;  4Y0Z I;  1F5R I;  3FP6 I;  1AAL A;  1BZ5 A;  1KTH A;  1K6U A;  4Y0Y I;  2FI3 I;  3M7Q B;  3CI7 A;  3LDJ A;  1DEM A;  1OA5 5;  3WNY A;  4NTX B;  1JV9 A;  2M99 A;  1YC0 I;  2J6D A;  4U30 W;  3AUC A;  2DDI A;  1TAW B;  1BHC A;  2ODY E;  1B0C A;  2LFK A;  1NAG A;  2KAI I;  1G6X A;  1PIT A;  1EJM B;  1UUB A;  3GYM I;  1LD5 A;  4NTY B;  1BF0 A;  2CA7 A;  1BIK A;  1MTN D;  1TOC R;  3AUE A;  3TGK I;  3AUB A;  1P2J I;  3P95 E;  1OA6 5;  2HEX A;  3BTK I;  1D0D B;  2IJO I;  1EAW B;  4BNR I;  2KNT A;  3TGI I;  1CO7 I;  2W8X A;  3P92 E;  3BTW I;  2DDJ A;  3AUD A;  5JB7 A;  1KIG I;  1ZJD B;  3BTE I;  1YKT B;  3BTH I;  1IRH A;  4ISO B;  1DTX A;  1DEN A;  2KCR A;  5C67 C;  3L3T E;  1KNT A;  2JOT A;  1P2M B;  4BD9 B;  1BTI A;  2FI5 I;  4WWY C;  4WXV C;  1P2N B;  9PTI A;  5JB4 A;  3T62 D;  2TGP I;  1FAN A;  2R9P E;  2TPI I;  1YLD B;  1BZX I;  7PTI A;  2ZJX A;  3TGJ I;  3FP7 J;  5JB5 A;  2FTL I;  1T8M B;  3L33 E;  3AUG A;  1BTH P;  3AUH A;  5JB6 A;  2M01 A;  1Y62 A;  1YLC B;  3BTT I;  3BTF I;  1BPT A;  1T8L B;  8PTI A;  1DTK A;  4BQD A;  4Y11 I;  1F7Z I;  1P2K I;  1JV8 A;  1BRC I;  4ISN B;  1BRB I;  3BTD I;  1BUN B;  1KUN A;  2FI4 I;  1ADZ A;  1BPI A;  3LDI A;  6PTI A;  1P2O B;  3FP8 I;  3BYB A;  4ISL B;  1D0D A;  3LDM A;  3OFW A;  3AUI A;  3D65 I;  3TPI I;  1T7C B;  4Y10 I;  3BTG I;  1T8N B;  1ZR0 B;  3UOU B;  2ZVX A;  2UUX A;  4NTW B;  1AAP A;  4TPI I;  1FAK I;  1QLQ A;  3U1J E;  1TFX C;  1TPA I;  2FTM B; 
#chains in the Genus database with same CATH homology
 1CBW D;  3BTM I;  3OTJ I;  2UUY B;  1FY8 I;  1TAP A;  1JC6 A;  4U32 X;  2RA3 C;  2PTC I;  1CA0 D;  4DTG K;  3UIR C;  4DG4 C;  1P2I I;  1P2Q B;  1LD6 A;  1UUA A;  4PTI A;  2LFL A;  1SHP A;  3BTQ I;  1TCP A;  1T8O B;  5PTI A;  4Y0Z I;  1F5R I;  3FP6 I;  1AAL A;  1BZ5 A;  1KTH A;  1K6U A;  4Y0Y I;  2FI3 I;  3M7Q B;  3CI7 A;  3LDJ A;  1DEM A;  1OA5 5;  3WNY A;  4NTX B;  1JV9 A;  2M99 A;  1YC0 I;  2J6D A;  4U30 W;  3AUC A;  2DDI A;  1TAW B;  1BHC A;  2ODY E;  1B0C A;  2LFK A;  1NAG A;  2KAI I;  1G6X A;  1PIT A;  1EJM B;  1UUB A;  3GYM I;  1LD5 A;  4NTY B;  1BF0 A;  2CA7 A;  1BIK A;  1MTN D;  1TOC R;  3AUE A;  3TGK I;  3AUB A;  1P2J I;  3P95 E;  1OA6 5;  2HEX A;  3BTK I;  1D0D B;  2IJO I;  1EAW B;  4BNR I;  2KNT A;  3TGI I;  1CO7 I;  2W8X A;  3P92 E;  3BTW I;  2DDJ A;  3AUD A;  5JB7 A;  1KIG I;  1ZJD B;  3BTE I;  1YKT B;  3BTH I;  1IRH A;  4ISO B;  1DTX A;  1DEN A;  2KCR A;  5C67 C;  3L3T E;  1KNT A;  2JOT A;  1P2M B;  4BD9 B;  1BTI A;  2FI5 I;  4WWY C;  4WXV C;  1P2N B;  9PTI A;  5JB4 A;  3T62 D;  2TGP I;  1FAN A;  2R9P E;  2TPI I;  1YLD B;  1BZX I;  7PTI A;  2ZJX A;  3TGJ I;  3FP7 J;  5JB5 A;  2FTL I;  1T8M B;  3L33 E;  3AUG A;  1BTH P;  3AUH A;  5JB6 A;  2M01 A;  1Y62 A;  1YLC B;  3BTT I;  3BTF I;  1BPT A;  1T8L B;  8PTI A;  1DTK A;  4BQD A;  4Y11 I;  1F7Z I;  1P2K I;  1JV8 A;  1BRC I;  4ISN B;  1BRB I;  3BTD I;  1BUN B;  1KUN A;  2FI4 I;  1ADZ A;  1BPI A;  3LDI A;  6PTI A;  1P2O B;  3FP8 I;  3BYB A;  4ISL B;  1D0D A;  3LDM A;  3OFW A;  3AUI A;  3D65 I;  3TPI I;  1T7C B;  4Y10 I;  3BTG I;  1T8N B;  1ZR0 B;  3UOU B;  2ZVX A;  2UUX A;  4NTW B;  1AAP A;  4TPI I;  1FAK I;  1QLQ A;  3U1J E;  1TFX C;  1TPA I;  2FTM B; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...