1BTIA

Crevice-forming mutants in the rigid core of bovine pancreatic trypsin inhibitor: crystal structures of f22a, y23a, n43g, and f45a
Total Genus 9
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
58
structure length
58
Chain Sequence
RPDFCLEPPYTGPCKARIIRYAYNAKAGLCQTFVYGGCRAKRNNFKSAEDCMRTCGGA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crevice-forming mutants in the rigid core of bovine pancreatic trypsin inhibitor: crystal structures of F22A, Y23A, N43G, and F45A.
pubmed rcsb
molecule tags Serine protease inhibitor
source organism Bos taurus
molecule keywords BOVINE PANCREATIC TRYPSIN INHIBITOR
total genus 9
structure length 58
sequence length 58
ec nomenclature
pdb deposition date 1991-07-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 1btiA00
1TPAI 2CA7A 2ZJXA 4NTYB 1MTND 1BZXI 1P2KI 1TOCR 3BTHI 3AUIA 4Y10I 1BHCA 1P2QB 2M01A 2KCRA 3TGKI 1P2OB 1LD5A 1F7ZI 1EJMB 1T7CB 1YLDB 3AUHA 1KIGI 1AAPA 3AUEA 3OFWA 1BRBI 5JB7A 1F5RI 4BD9B 1P2II 3BTFI 3BTGI 5JB4A 4ISNB 3LDMA 3TPII 5JB6A 2DDJA 2FTLI 3FP6I 1P2MB 1KUNA 4U32X 1TCPA 1B0CA 2LFLA 3BTEI 2KNTA 3AUCA 1BF0A 1IRHA 1G6XA 3AUGA 1TAPA 3L3TE 5C67C 1BZ5A 1DTKA 1DEMA 1ZJDB 2HEXA 1JV8A 2R9PE 6PTIA 1YC0I 1CO7I 1FANA 2W8XA 9PTIA 1BPIA 2ODYE 3LDJA 1DENA 1D0DA 7PTIA 1SHPA 2TPII 3D65I 4NTWB 1DTXA 2FI4I 4NTXB 3AUDA 1BTHP 1NAGA 1KTHA 1T8LB 3GYMI 1UUBA 2LFKA 3BTDI 4WXVC 1T8NB 3BTMI 3UIRC 3L33E 1YKTB 1BPTA 1Y62A 3CI7A 2J6DA 4Y0YI 3WNYA 1T8OB 3BTTI 1EAWB 3BTKI 4ISOB 2FI5I 1TAWB 3AUBA 1T8MB 1ADZA 2DDIA 4BNRI 8PTIA 3BTWI 1P2NB 1OA65 1TFXC 4PTIA 4Y0ZI 1AALA 1JC6A 1BRCI 2UUYB 1P2JI 2KAII 3BYBA 2M99A 1PITA 3FP7J 2FTMB 1KNTA 5JB5A 4TPII 2PTCI 3TGII 1UUAA 2FI3I 1CA0D 3T62D 4BQDA 2RA3C 3P95E 3TGJI 3FP8I 2UUXA 1ZR0B 1JV9A 3M7QB 4U30W 1BUNB 4DTGK 1K6UA 1YLCB 1FAKI 5PTIA 1FY8I 3P92E 3BTQI 3OTJI 1D0DB 4Y11I 1LD6A 1BIKA 1BTIA 4WWYC 2JOTA 3U1JE 2ZVXA 2IJOI 1CBWD 1QLQA 3UOUB 4ISLB 4DG4C 2TGPI 1OA55 3LDIA
chains in the Genus database with same CATH superfamily
1TPAI 2CA7A 2ZJXA 4NTYB 1MTND 1BZXI 1P2KI 1TOCR 3BTHI 3AUIA 4Y10I 1BHCA 1P2QB 2M01A 2KCRA 3TGKI 1P2OB 1LD5A 1F7ZI 1EJMB 1T7CB 1YLDB 3AUHA 1KIGI 1AAPA 3AUEA 3OFWA 1BRBI 5JB7A 1F5RI 4BD9B 1P2II 3BTFI 3BTGI 5JB4A 4ISNB 3LDMA 3TPII 5JB6A 2DDJA 2FTLI 3FP6I 1P2MB 1KUNA 4U32X 1TCPA 1B0CA 2LFLA 3BTEI 2KNTA 3AUCA 1BF0A 1IRHA 1G6XA 3AUGA 1TAPA 3L3TE 5C67C 1BZ5A 1DTKA 1DEMA 1ZJDB 2HEXA 1JV8A 2R9PE 6PTIA 1YC0I 1CO7I 1FANA 2W8XA 9PTIA 1BPIA 2ODYE 3LDJA 1DENA 1D0DA 7PTIA 1SHPA 2TPII 3D65I 4NTWB 1DTXA 2FI4I 4NTXB 3AUDA 1BTHP 1NAGA 1KTHA 1T8LB 3GYMI 1UUBA 2LFKA 3BTDI 4WXVC 1T8NB 3BTMI 3UIRC 3L33E 1YKTB 1BPTA 1Y62A 3CI7A 2J6DA 4Y0YI 3WNYA 1T8OB 3BTTI 1EAWB 3BTKI 4ISOB 2FI5I 1TAWB 3AUBA 1T8MB 1ADZA 2DDIA 4BNRI 8PTIA 3BTWI 1P2NB 1OA65 1TFXC 4PTIA 4Y0ZI 1AALA 1JC6A 1BRCI 2UUYB 1P2JI 2KAII 3BYBA 2M99A 1PITA 3FP7J 2FTMB 1KNTA 5JB5A 4TPII 2PTCI 3TGII 1UUAA 2FI3I 1CA0D 3T62D 4BQDA 2RA3C 3P95E 3TGJI 3FP8I 2UUXA 1ZR0B 1JV9A 3M7QB 4U30W 1BUNB 4DTGK 1K6UA 1YLCB 1FAKI 5PTIA 1FY8I 3P92E 3BTQI 3OTJI 1D0DB 4Y11I 1LD6A 1BIKA 1BTIA 4WWYC 2JOTA 3U1JE 2ZVXA 2IJOI 1CBWD 1QLQA 3UOUB 4ISLB 4DG4C 2TGPI 1OA55 3LDIA
chains in the Genus database with same CATH topology
1TPAI 2CA7A 2ZJXA 4NTYB 1MTND 1BZXI 1P2KI 1TOCR 3BTHI 3AUIA 4Y10I 1BHCA 1P2QB 2M01A 2KCRA 3TGKI 1P2OB 1LD5A 1F7ZI 1EJMB 1T7CB 1YLDB 3AUHA 1KIGI 1AAPA 3AUEA 3OFWA 1BRBI 5JB7A 1F5RI 4BD9B 1P2II 3BTFI 3BTGI 5JB4A 4ISNB 3LDMA 3TPII 5JB6A 2DDJA 2FTLI 3FP6I 1P2MB 1KUNA 4U32X 1TCPA 1B0CA 2LFLA 3BTEI 2KNTA 3AUCA 1BF0A 1IRHA 1G6XA 3AUGA 1TAPA 3L3TE 5C67C 1BZ5A 1DTKA 1DEMA 1ZJDB 2HEXA 1JV8A 2R9PE 6PTIA 1YC0I 1CO7I 1FANA 2W8XA 9PTIA 1BPIA 2ODYE 3LDJA 1DENA 1D0DA 7PTIA 1SHPA 2TPII 3D65I 4NTWB 1DTXA 2FI4I 4NTXB 3AUDA 1BTHP 1NAGA 1KTHA 1T8LB 3GYMI 1UUBA 2LFKA 3BTDI 4WXVC 1T8NB 3BTMI 3UIRC 3L33E 1YKTB 1BPTA 1Y62A 3CI7A 2J6DA 4Y0YI 3WNYA 1T8OB 3BTTI 1EAWB 3BTKI 4ISOB 2FI5I 1TAWB 3AUBA 1T8MB 1ADZA 2DDIA 4BNRI 8PTIA 3BTWI 1P2NB 1OA65 1TFXC 4PTIA 4Y0ZI 1AALA 1JC6A 1BRCI 2UUYB 1P2JI 2KAII 3BYBA 2M99A 1PITA 3FP7J 2FTMB 1KNTA 5JB5A 4TPII 2PTCI 3TGII 1UUAA 2FI3I 1CA0D 3T62D 4BQDA 2RA3C 3P95E 3TGJI 3FP8I 2UUXA 1ZR0B 1JV9A 3M7QB 4U30W 1BUNB 4DTGK 1K6UA 1YLCB 1FAKI 5PTIA 1FY8I 3P92E 3BTQI 3OTJI 1D0DB 4Y11I 1LD6A 1BIKA 1BTIA 4WWYC 2JOTA 3U1JE 2ZVXA 2IJOI 1CBWD 1QLQA 3UOUB 4ISLB 4DG4C 2TGPI 1OA55 3LDIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TPA I;  2CA7 A;  2ZJX A;  4NTY B;  1MTN D;  1BZX I;  1P2K I;  1TOC R;  3BTH I;  3AUI A;  4Y10 I;  1BHC A;  1P2Q B;  2M01 A;  2KCR A;  3TGK I;  1P2O B;  1LD5 A;  1F7Z I;  1EJM B;  1T7C B;  1YLD B;  3AUH A;  1KIG I;  1AAP A;  3AUE A;  3OFW A;  1BRB I;  5JB7 A;  1F5R I;  4BD9 B;  1P2I I;  3BTF I;  3BTG I;  5JB4 A;  4ISN B;  3LDM A;  3TPI I;  5JB6 A;  2DDJ A;  2FTL I;  3FP6 I;  1P2M B;  1KUN A;  4U32 X;  1TCP A;  1B0C A;  2LFL A;  3BTE I;  2KNT A;  3AUC A;  1BF0 A;  1IRH A;  1G6X A;  3AUG A;  1TAP A;  3L3T E;  5C67 C;  1BZ5 A;  1DTK A;  1DEM A;  1ZJD B;  2HEX A;  1JV8 A;  2R9P E;  6PTI A;  1YC0 I;  1CO7 I;  1FAN A;  2W8X A;  9PTI A;  1BPI A;  2ODY E;  3LDJ A;  1DEN A;  1D0D A;  7PTI A;  1SHP A;  2TPI I;  3D65 I;  4NTW B;  1DTX A;  2FI4 I;  4NTX B;  3AUD A;  1BTH P;  1NAG A;  1KTH A;  1T8L B;  3GYM I;  1UUB A;  2LFK A;  3BTD I;  4WXV C;  1T8N B;  3BTM I;  3UIR C;  3L33 E;  1YKT B;  1BPT A;  1Y62 A;  3CI7 A;  2J6D A;  4Y0Y I;  3WNY A;  1T8O B;  3BTT I;  1EAW B;  3BTK I;  4ISO B;  2FI5 I;  1TAW B;  3AUB A;  1T8M B;  1ADZ A;  2DDI A;  4BNR I;  8PTI A;  3BTW I;  1P2N B;  1OA6 5;  1TFX C;  4PTI A;  4Y0Z I;  1AAL A;  1JC6 A;  1BRC I;  2UUY B;  1P2J I;  2KAI I;  3BYB A;  2M99 A;  1PIT A;  3FP7 J;  2FTM B;  1KNT A;  5JB5 A;  4TPI I;  2PTC I;  3TGI I;  1UUA A;  2FI3 I;  1CA0 D;  3T62 D;  4BQD A;  2RA3 C;  3P95 E;  3TGJ I;  3FP8 I;  2UUX A;  1ZR0 B;  1JV9 A;  3M7Q B;  4U30 W;  1BUN B;  4DTG K;  1K6U A;  1YLC B;  1FAK I;  5PTI A;  1FY8 I;  3P92 E;  3BTQ I;  3OTJ I;  1D0D B;  4Y11 I;  1LD6 A;  1BIK A;  1BTI A;  4WWY C;  2JOT A;  3U1J E;  2ZVX A;  2IJO I;  1CBW D;  1QLQ A;  3UOU B;  4ISL B;  4DG4 C;  2TGP I;  1OA5 5;  3LDI A; 
#chains in the Genus database with same CATH topology
 1TPA I;  2CA7 A;  2ZJX A;  4NTY B;  1MTN D;  1BZX I;  1P2K I;  1TOC R;  3BTH I;  3AUI A;  4Y10 I;  1BHC A;  1P2Q B;  2M01 A;  2KCR A;  3TGK I;  1P2O B;  1LD5 A;  1F7Z I;  1EJM B;  1T7C B;  1YLD B;  3AUH A;  1KIG I;  1AAP A;  3AUE A;  3OFW A;  1BRB I;  5JB7 A;  1F5R I;  4BD9 B;  1P2I I;  3BTF I;  3BTG I;  5JB4 A;  4ISN B;  3LDM A;  3TPI I;  5JB6 A;  2DDJ A;  2FTL I;  3FP6 I;  1P2M B;  1KUN A;  4U32 X;  1TCP A;  1B0C A;  2LFL A;  3BTE I;  2KNT A;  3AUC A;  1BF0 A;  1IRH A;  1G6X A;  3AUG A;  1TAP A;  3L3T E;  5C67 C;  1BZ5 A;  1DTK A;  1DEM A;  1ZJD B;  2HEX A;  1JV8 A;  2R9P E;  6PTI A;  1YC0 I;  1CO7 I;  1FAN A;  2W8X A;  9PTI A;  1BPI A;  2ODY E;  3LDJ A;  1DEN A;  1D0D A;  7PTI A;  1SHP A;  2TPI I;  3D65 I;  4NTW B;  1DTX A;  2FI4 I;  4NTX B;  3AUD A;  1BTH P;  1NAG A;  1KTH A;  1T8L B;  3GYM I;  1UUB A;  2LFK A;  3BTD I;  4WXV C;  1T8N B;  3BTM I;  3UIR C;  3L33 E;  1YKT B;  1BPT A;  1Y62 A;  3CI7 A;  2J6D A;  4Y0Y I;  3WNY A;  1T8O B;  3BTT I;  1EAW B;  3BTK I;  4ISO B;  2FI5 I;  1TAW B;  3AUB A;  1T8M B;  1ADZ A;  2DDI A;  4BNR I;  8PTI A;  3BTW I;  1P2N B;  1OA6 5;  1TFX C;  4PTI A;  4Y0Z I;  1AAL A;  1JC6 A;  1BRC I;  2UUY B;  1P2J I;  2KAI I;  3BYB A;  2M99 A;  1PIT A;  3FP7 J;  2FTM B;  1KNT A;  5JB5 A;  4TPI I;  2PTC I;  3TGI I;  1UUA A;  2FI3 I;  1CA0 D;  3T62 D;  4BQD A;  2RA3 C;  3P95 E;  3TGJ I;  3FP8 I;  2UUX A;  1ZR0 B;  1JV9 A;  3M7Q B;  4U30 W;  1BUN B;  4DTG K;  1K6U A;  1YLC B;  1FAK I;  5PTI A;  1FY8 I;  3P92 E;  3BTQ I;  3OTJ I;  1D0D B;  4Y11 I;  1LD6 A;  1BIK A;  1BTI A;  4WWY C;  2JOT A;  3U1J E;  2ZVX A;  2IJO I;  1CBW D;  1QLQ A;  3UOU B;  4ISL B;  4DG4 C;  2TGP I;  1OA5 5;  3LDI A; 
#chains in the Genus database with same CATH homology
 1TPA I;  2CA7 A;  2ZJX A;  4NTY B;  1MTN D;  1BZX I;  1P2K I;  1TOC R;  3BTH I;  3AUI A;  4Y10 I;  1BHC A;  1P2Q B;  2M01 A;  2KCR A;  3TGK I;  1P2O B;  1LD5 A;  1F7Z I;  1EJM B;  1T7C B;  1YLD B;  3AUH A;  1KIG I;  1AAP A;  3AUE A;  3OFW A;  1BRB I;  5JB7 A;  1F5R I;  4BD9 B;  1P2I I;  3BTF I;  3BTG I;  5JB4 A;  4ISN B;  3LDM A;  3TPI I;  5JB6 A;  2DDJ A;  2FTL I;  3FP6 I;  1P2M B;  1KUN A;  4U32 X;  1TCP A;  1B0C A;  2LFL A;  3BTE I;  2KNT A;  3AUC A;  1BF0 A;  1IRH A;  1G6X A;  3AUG A;  1TAP A;  3L3T E;  5C67 C;  1BZ5 A;  1DTK A;  1DEM A;  1ZJD B;  2HEX A;  1JV8 A;  2R9P E;  6PTI A;  1YC0 I;  1CO7 I;  1FAN A;  2W8X A;  9PTI A;  1BPI A;  2ODY E;  3LDJ A;  1DEN A;  1D0D A;  7PTI A;  1SHP A;  2TPI I;  3D65 I;  4NTW B;  1DTX A;  2FI4 I;  4NTX B;  3AUD A;  1BTH P;  1NAG A;  1KTH A;  1T8L B;  3GYM I;  1UUB A;  2LFK A;  3BTD I;  4WXV C;  1T8N B;  3BTM I;  3UIR C;  3L33 E;  1YKT B;  1BPT A;  1Y62 A;  3CI7 A;  2J6D A;  4Y0Y I;  3WNY A;  1T8O B;  3BTT I;  1EAW B;  3BTK I;  4ISO B;  2FI5 I;  1TAW B;  3AUB A;  1T8M B;  1ADZ A;  2DDI A;  4BNR I;  8PTI A;  3BTW I;  1P2N B;  1OA6 5;  1TFX C;  4PTI A;  4Y0Z I;  1AAL A;  1JC6 A;  1BRC I;  2UUY B;  1P2J I;  2KAI I;  3BYB A;  2M99 A;  1PIT A;  3FP7 J;  2FTM B;  1KNT A;  5JB5 A;  4TPI I;  2PTC I;  3TGI I;  1UUA A;  2FI3 I;  1CA0 D;  3T62 D;  4BQD A;  2RA3 C;  3P95 E;  3TGJ I;  3FP8 I;  2UUX A;  1ZR0 B;  1JV9 A;  3M7Q B;  4U30 W;  1BUN B;  4DTG K;  1K6U A;  1YLC B;  1FAK I;  5PTI A;  1FY8 I;  3P92 E;  3BTQ I;  3OTJ I;  1D0D B;  4Y11 I;  1LD6 A;  1BIK A;  1BTI A;  4WWY C;  2JOT A;  3U1J E;  2ZVX A;  2IJO I;  1CBW D;  1QLQ A;  3UOU B;  4ISL B;  4DG4 C;  2TGP I;  1OA5 5;  3LDI A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...