1DENA

Proteinase inhibitor homologues as potassium channel blockers
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
60
structure length
60
Chain Sequence
QPLRKLCILHRNPGRCYQKIPAFYYNQKKKQCEGFTWSGCGGNSNRFKTIEECRRTCIRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Proteinase inhibitor homologues as potassium channel blockers.
pubmed doi rcsb
molecule tags Venom(potassium channel inhibitor)
source organism Dendroaspis polylepis polylepis
molecule keywords DENDROTOXIN I
total genus 5
structure length 60
sequence length 60
ec nomenclature
pdb deposition date 1994-03-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 1denA00
1BIKA 1KUNA 1SHPA 1B0CA 1ADZA 1P2OB 1ZJDB 4ISLB 1OA55 1BTHP 3L33E 1FY8I 3TGII 4U30W 3TPII 8PTIA 1DEMA 3BTEI 3TGJI 2FI4I 1TOCR 1CO7I 2FTMB 2TPII 4WXVC 4Y0YI 4Y0ZI 4ISNB 2RA3C 1BRBI 1D0DA 1P2MB 2FI5I 3GYMI 4TPII 1BPTA 3BTKI 1EAWB 2PTCI 3AUEA 2DDJA 1IRHA 1Y62A 3U1JE 1TPAI 1FAKI 2CA7A 3T62D 3BTGI 2LFKA 3FP6I 2HEXA 3TGKI 2UUYB 1PITA 4DTGK 1DTXA 1T8MB 4DG4C 1TCPA 3FP8I 1T8LB 1KNTA 4BNRI 1EJMB 2FI3I 1JV8A 4NTXB 1T7CB 2ODYE 3UIRC 2IJOI 2J6DA 3UOUB 1TAPA 1NAGA 3AUDA 1BRCI 1BHCA 6PTIA 2KCRA 1LD6A 1QLQA 1YLDB 3LDMA 4NTYB 4BQDA 2DDIA 2ZJXA 3BTFI 1LD5A 3AUBA 1DENA 1BPIA 1YKTB 1UUBA 5JB5A 2KAII 2TGPI 4Y11I 1CBWD 1G6XA 2W8XA 4BD9B 2ZVXA 1BZ5A 1P2KI 1D0DB 3P92E 3BTQI 1OA65 2LFLA 1P2QB 1P2NB 1KIGI 1T8OB 1JC6A 4U32X 1UUAA 3BTHI 1ZR0B 2FTLI 1BUNB 3D65I 5PTIA 3AUCA 3OTJI 1BTIA 5JB4A 3LDJA 1TAWB 1F5RI 3BTTI 1DTKA 3CI7A 1JV9A 7PTIA 4Y10I 5JB6A 1P2JI 3OFWA 1CA0D 3BYBA 3WNYA 3FP7J 2UUXA 3M7QB 1TFXC 3BTDI 3L3TE 3BTMI 2M01A 1YLCB 1F7ZI 3LDIA 3P95E 1BF0A 3AUIA 1AAPA 5C67C 4ISOB 3AUHA 2JOTA 9PTIA 1K6UA 2KNTA 1YC0I 1P2II 1FANA 1KTHA 1T8NB 3AUGA 1MTND 1AALA 2M99A 1BZXI 3BTWI 4WWYC 5JB7A 2R9PE 4PTIA 4NTWB
chains in the Genus database with same CATH superfamily
1BIKA 1KUNA 1SHPA 1B0CA 1ADZA 1P2OB 1ZJDB 4ISLB 1OA55 1BTHP 3L33E 1FY8I 3TGII 4U30W 3TPII 8PTIA 1DEMA 3BTEI 3TGJI 2FI4I 1TOCR 1CO7I 2FTMB 2TPII 4WXVC 4Y0YI 4Y0ZI 4ISNB 2RA3C 1BRBI 1D0DA 1P2MB 2FI5I 3GYMI 4TPII 1BPTA 3BTKI 1EAWB 2PTCI 3AUEA 2DDJA 1IRHA 1Y62A 3U1JE 1TPAI 1FAKI 2CA7A 3T62D 3BTGI 2LFKA 3FP6I 2HEXA 3TGKI 2UUYB 1PITA 4DTGK 1DTXA 1T8MB 4DG4C 1TCPA 3FP8I 1T8LB 1KNTA 4BNRI 1EJMB 2FI3I 1JV8A 4NTXB 1T7CB 2ODYE 3UIRC 2IJOI 2J6DA 3UOUB 1TAPA 1NAGA 3AUDA 1BRCI 1BHCA 6PTIA 2KCRA 1LD6A 1QLQA 1YLDB 3LDMA 4NTYB 4BQDA 2DDIA 2ZJXA 3BTFI 1LD5A 3AUBA 1DENA 1BPIA 1YKTB 1UUBA 5JB5A 2KAII 2TGPI 4Y11I 1CBWD 1G6XA 2W8XA 4BD9B 2ZVXA 1BZ5A 1P2KI 1D0DB 3P92E 3BTQI 1OA65 2LFLA 1P2QB 1P2NB 1KIGI 1T8OB 1JC6A 4U32X 1UUAA 3BTHI 1ZR0B 2FTLI 1BUNB 3D65I 5PTIA 3AUCA 3OTJI 1BTIA 5JB4A 3LDJA 1TAWB 1F5RI 3BTTI 1DTKA 3CI7A 1JV9A 7PTIA 4Y10I 5JB6A 1P2JI 3OFWA 1CA0D 3BYBA 3WNYA 3FP7J 2UUXA 3M7QB 1TFXC 3BTDI 3L3TE 3BTMI 2M01A 1YLCB 1F7ZI 3LDIA 3P95E 1BF0A 3AUIA 1AAPA 5C67C 4ISOB 3AUHA 2JOTA 9PTIA 1K6UA 2KNTA 1YC0I 1P2II 1FANA 1KTHA 1T8NB 3AUGA 1MTND 1AALA 2M99A 1BZXI 3BTWI 4WWYC 5JB7A 2R9PE 4PTIA 4NTWB
chains in the Genus database with same CATH topology
1BIKA 1KUNA 1SHPA 1B0CA 1ADZA 1P2OB 1ZJDB 4ISLB 1OA55 1BTHP 3L33E 1FY8I 3TGII 4U30W 3TPII 8PTIA 1DEMA 3BTEI 3TGJI 2FI4I 1TOCR 1CO7I 2FTMB 2TPII 4WXVC 4Y0YI 4Y0ZI 4ISNB 2RA3C 1BRBI 1D0DA 1P2MB 2FI5I 3GYMI 4TPII 1BPTA 3BTKI 1EAWB 2PTCI 3AUEA 2DDJA 1IRHA 1Y62A 3U1JE 1TPAI 1FAKI 2CA7A 3T62D 3BTGI 2LFKA 3FP6I 2HEXA 3TGKI 2UUYB 1PITA 4DTGK 1DTXA 1T8MB 4DG4C 1TCPA 3FP8I 1T8LB 1KNTA 4BNRI 1EJMB 2FI3I 1JV8A 4NTXB 1T7CB 2ODYE 3UIRC 2IJOI 2J6DA 3UOUB 1TAPA 1NAGA 3AUDA 1BRCI 1BHCA 6PTIA 2KCRA 1LD6A 1QLQA 1YLDB 3LDMA 4NTYB 4BQDA 2DDIA 2ZJXA 3BTFI 1LD5A 3AUBA 1DENA 1BPIA 1YKTB 1UUBA 5JB5A 2KAII 2TGPI 4Y11I 1CBWD 1G6XA 2W8XA 4BD9B 2ZVXA 1BZ5A 1P2KI 1D0DB 3P92E 3BTQI 1OA65 2LFLA 1P2QB 1P2NB 1KIGI 1T8OB 1JC6A 4U32X 1UUAA 3BTHI 1ZR0B 2FTLI 1BUNB 3D65I 5PTIA 3AUCA 3OTJI 1BTIA 5JB4A 3LDJA 1TAWB 1F5RI 3BTTI 1DTKA 3CI7A 1JV9A 7PTIA 4Y10I 5JB6A 1P2JI 3OFWA 1CA0D 3BYBA 3WNYA 3FP7J 2UUXA 3M7QB 1TFXC 3BTDI 3L3TE 3BTMI 2M01A 1YLCB 1F7ZI 3LDIA 3P95E 1BF0A 3AUIA 1AAPA 5C67C 4ISOB 3AUHA 2JOTA 9PTIA 1K6UA 2KNTA 1YC0I 1P2II 1FANA 1KTHA 1T8NB 3AUGA 1MTND 1AALA 2M99A 1BZXI 3BTWI 4WWYC 5JB7A 2R9PE 4PTIA 4NTWB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BIK A;  1KUN A;  1SHP A;  1B0C A;  1ADZ A;  1P2O B;  1ZJD B;  4ISL B;  1OA5 5;  1BTH P;  3L33 E;  1FY8 I;  3TGI I;  4U30 W;  3TPI I;  8PTI A;  1DEM A;  3BTE I;  3TGJ I;  2FI4 I;  1TOC R;  1CO7 I;  2FTM B;  2TPI I;  4WXV C;  4Y0Y I;  4Y0Z I;  4ISN B;  2RA3 C;  1BRB I;  1D0D A;  1P2M B;  2FI5 I;  3GYM I;  4TPI I;  1BPT A;  3BTK I;  1EAW B;  2PTC I;  3AUE A;  2DDJ A;  1IRH A;  1Y62 A;  3U1J E;  1TPA I;  1FAK I;  2CA7 A;  3T62 D;  3BTG I;  2LFK A;  3FP6 I;  2HEX A;  3TGK I;  2UUY B;  1PIT A;  4DTG K;  1DTX A;  1T8M B;  4DG4 C;  1TCP A;  3FP8 I;  1T8L B;  1KNT A;  4BNR I;  1EJM B;  2FI3 I;  1JV8 A;  4NTX B;  1T7C B;  2ODY E;  3UIR C;  2IJO I;  2J6D A;  3UOU B;  1TAP A;  1NAG A;  3AUD A;  1BRC I;  1BHC A;  6PTI A;  2KCR A;  1LD6 A;  1QLQ A;  1YLD B;  3LDM A;  4NTY B;  4BQD A;  2DDI A;  2ZJX A;  3BTF I;  1LD5 A;  3AUB A;  1DEN A;  1BPI A;  1YKT B;  1UUB A;  5JB5 A;  2KAI I;  2TGP I;  4Y11 I;  1CBW D;  1G6X A;  2W8X A;  4BD9 B;  2ZVX A;  1BZ5 A;  1P2K I;  1D0D B;  3P92 E;  3BTQ I;  1OA6 5;  2LFL A;  1P2Q B;  1P2N B;  1KIG I;  1T8O B;  1JC6 A;  4U32 X;  1UUA A;  3BTH I;  1ZR0 B;  2FTL I;  1BUN B;  3D65 I;  5PTI A;  3AUC A;  3OTJ I;  1BTI A;  5JB4 A;  3LDJ A;  1TAW B;  1F5R I;  3BTT I;  1DTK A;  3CI7 A;  1JV9 A;  7PTI A;  4Y10 I;  5JB6 A;  1P2J I;  3OFW A;  1CA0 D;  3BYB A;  3WNY A;  3FP7 J;  2UUX A;  3M7Q B;  1TFX C;  3BTD I;  3L3T E;  3BTM I;  2M01 A;  1YLC B;  1F7Z I;  3LDI A;  3P95 E;  1BF0 A;  3AUI A;  1AAP A;  5C67 C;  4ISO B;  3AUH A;  2JOT A;  9PTI A;  1K6U A;  2KNT A;  1YC0 I;  1P2I I;  1FAN A;  1KTH A;  1T8N B;  3AUG A;  1MTN D;  1AAL A;  2M99 A;  1BZX I;  3BTW I;  4WWY C;  5JB7 A;  2R9P E;  4PTI A;  4NTW B; 
#chains in the Genus database with same CATH topology
 1BIK A;  1KUN A;  1SHP A;  1B0C A;  1ADZ A;  1P2O B;  1ZJD B;  4ISL B;  1OA5 5;  1BTH P;  3L33 E;  1FY8 I;  3TGI I;  4U30 W;  3TPI I;  8PTI A;  1DEM A;  3BTE I;  3TGJ I;  2FI4 I;  1TOC R;  1CO7 I;  2FTM B;  2TPI I;  4WXV C;  4Y0Y I;  4Y0Z I;  4ISN B;  2RA3 C;  1BRB I;  1D0D A;  1P2M B;  2FI5 I;  3GYM I;  4TPI I;  1BPT A;  3BTK I;  1EAW B;  2PTC I;  3AUE A;  2DDJ A;  1IRH A;  1Y62 A;  3U1J E;  1TPA I;  1FAK I;  2CA7 A;  3T62 D;  3BTG I;  2LFK A;  3FP6 I;  2HEX A;  3TGK I;  2UUY B;  1PIT A;  4DTG K;  1DTX A;  1T8M B;  4DG4 C;  1TCP A;  3FP8 I;  1T8L B;  1KNT A;  4BNR I;  1EJM B;  2FI3 I;  1JV8 A;  4NTX B;  1T7C B;  2ODY E;  3UIR C;  2IJO I;  2J6D A;  3UOU B;  1TAP A;  1NAG A;  3AUD A;  1BRC I;  1BHC A;  6PTI A;  2KCR A;  1LD6 A;  1QLQ A;  1YLD B;  3LDM A;  4NTY B;  4BQD A;  2DDI A;  2ZJX A;  3BTF I;  1LD5 A;  3AUB A;  1DEN A;  1BPI A;  1YKT B;  1UUB A;  5JB5 A;  2KAI I;  2TGP I;  4Y11 I;  1CBW D;  1G6X A;  2W8X A;  4BD9 B;  2ZVX A;  1BZ5 A;  1P2K I;  1D0D B;  3P92 E;  3BTQ I;  1OA6 5;  2LFL A;  1P2Q B;  1P2N B;  1KIG I;  1T8O B;  1JC6 A;  4U32 X;  1UUA A;  3BTH I;  1ZR0 B;  2FTL I;  1BUN B;  3D65 I;  5PTI A;  3AUC A;  3OTJ I;  1BTI A;  5JB4 A;  3LDJ A;  1TAW B;  1F5R I;  3BTT I;  1DTK A;  3CI7 A;  1JV9 A;  7PTI A;  4Y10 I;  5JB6 A;  1P2J I;  3OFW A;  1CA0 D;  3BYB A;  3WNY A;  3FP7 J;  2UUX A;  3M7Q B;  1TFX C;  3BTD I;  3L3T E;  3BTM I;  2M01 A;  1YLC B;  1F7Z I;  3LDI A;  3P95 E;  1BF0 A;  3AUI A;  1AAP A;  5C67 C;  4ISO B;  3AUH A;  2JOT A;  9PTI A;  1K6U A;  2KNT A;  1YC0 I;  1P2I I;  1FAN A;  1KTH A;  1T8N B;  3AUG A;  1MTN D;  1AAL A;  2M99 A;  1BZX I;  3BTW I;  4WWY C;  5JB7 A;  2R9P E;  4PTI A;  4NTW B; 
#chains in the Genus database with same CATH homology
 1BIK A;  1KUN A;  1SHP A;  1B0C A;  1ADZ A;  1P2O B;  1ZJD B;  4ISL B;  1OA5 5;  1BTH P;  3L33 E;  1FY8 I;  3TGI I;  4U30 W;  3TPI I;  8PTI A;  1DEM A;  3BTE I;  3TGJ I;  2FI4 I;  1TOC R;  1CO7 I;  2FTM B;  2TPI I;  4WXV C;  4Y0Y I;  4Y0Z I;  4ISN B;  2RA3 C;  1BRB I;  1D0D A;  1P2M B;  2FI5 I;  3GYM I;  4TPI I;  1BPT A;  3BTK I;  1EAW B;  2PTC I;  3AUE A;  2DDJ A;  1IRH A;  1Y62 A;  3U1J E;  1TPA I;  1FAK I;  2CA7 A;  3T62 D;  3BTG I;  2LFK A;  3FP6 I;  2HEX A;  3TGK I;  2UUY B;  1PIT A;  4DTG K;  1DTX A;  1T8M B;  4DG4 C;  1TCP A;  3FP8 I;  1T8L B;  1KNT A;  4BNR I;  1EJM B;  2FI3 I;  1JV8 A;  4NTX B;  1T7C B;  2ODY E;  3UIR C;  2IJO I;  2J6D A;  3UOU B;  1TAP A;  1NAG A;  3AUD A;  1BRC I;  1BHC A;  6PTI A;  2KCR A;  1LD6 A;  1QLQ A;  1YLD B;  3LDM A;  4NTY B;  4BQD A;  2DDI A;  2ZJX A;  3BTF I;  1LD5 A;  3AUB A;  1DEN A;  1BPI A;  1YKT B;  1UUB A;  5JB5 A;  2KAI I;  2TGP I;  4Y11 I;  1CBW D;  1G6X A;  2W8X A;  4BD9 B;  2ZVX A;  1BZ5 A;  1P2K I;  1D0D B;  3P92 E;  3BTQ I;  1OA6 5;  2LFL A;  1P2Q B;  1P2N B;  1KIG I;  1T8O B;  1JC6 A;  4U32 X;  1UUA A;  3BTH I;  1ZR0 B;  2FTL I;  1BUN B;  3D65 I;  5PTI A;  3AUC A;  3OTJ I;  1BTI A;  5JB4 A;  3LDJ A;  1TAW B;  1F5R I;  3BTT I;  1DTK A;  3CI7 A;  1JV9 A;  7PTI A;  4Y10 I;  5JB6 A;  1P2J I;  3OFW A;  1CA0 D;  3BYB A;  3WNY A;  3FP7 J;  2UUX A;  3M7Q B;  1TFX C;  3BTD I;  3L3T E;  3BTM I;  2M01 A;  1YLC B;  1F7Z I;  3LDI A;  3P95 E;  1BF0 A;  3AUI A;  1AAP A;  5C67 C;  4ISO B;  3AUH A;  2JOT A;  9PTI A;  1K6U A;  2KNT A;  1YC0 I;  1P2I I;  1FAN A;  1KTH A;  1T8N B;  3AUG A;  1MTN D;  1AAL A;  2M99 A;  1BZX I;  3BTW I;  4WWY C;  5JB7 A;  2R9P E;  4PTI A;  4NTW B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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