1DZFA

Rpb5 from s.cerevisiae
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
211
structure length
211
Chain Sequence
NERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Rpb5, a Universal Eukaryotic RNA Polymerase Subunit and Trascription Factor Interaction Target
pubmed doi rcsb
molecule tags Transferase
source organism Saccharomyces cerevisiae
molecule keywords DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1
total genus 67
structure length 211
sequence length 211
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2000-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
A PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 1dzfA01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 1dzfA02
4BBSE 4A3JE 5C44E 3M3YE 3RZOE 2WAQH 4A3EE 3S14E 1SFOE 4A3CE 2WB1H 3I4NE 1TWHE 5C3EE 5M5XE 3GTQE 2JA6E 3FKIE 3S1QE 4A3ME 4AYBH 1R9TE 4BY1E 4A93E 2PMZH 2E2HE 5C4XE 3CQZE 4C3IE 3HOWE 3HOZE 4C2ME 3S15E 3I4ME 1I3QE 3S16E 1TWAE 3RZDE 4A3LE 4BY7E 4A3GE 3H0GE 2NVYE 5IP7E 3S1NE 2E2IE 3S17E 4Y52E 2VUME 4A3FE 3M4OE 2JA5E 3S1ME 5M3FE 5FLME 2JA7E 5M3ME 4BXXE 4A3DE 3HKZH 4A3KE 3GTPE 1DZFA 1I50E 2R92E 3H3VF 5M5YE 1TWCE 3GTGE 3S2DE 1WCME 4A3IE 1EIKA 3HOYE 5M5WE 1Y1WE 4C3HE 3S1RE 3K7AE 2NVQE 3PO3E 1K83E 4Y7NE 4X6AE 3GTLE 2R93E 3HOUE 5IP9E 4C3JE 5IYDE 5FJ8E 3HOVE 3GTOE 2B63E 4BBRE 2R7ZE 5IYBE 3GTME 2YU9E 2Y0SH 5IYCE 3GTKE 2JA8E 3GTJE 3S2HE 1Y1VE 2NVTE 4A3BE 5C4JE 1I6HE 3PO2E 1TWFE 2NVXE 1TWGE 2E2JE 4QIWH 3HOXE
chains in the Genus database with same CATH superfamily
4A3EF 4BBSE 1I3QF 4A3JE 5C44E 3S14F 3S16F 3M3YE 3RZOE 1SFOF 4A3CF 4A3GF 4MQ9E 2WAQH 5TMCE 4A3EE 3I4NF 3S14E 1TWHF 1SFOE 4A3CE 4G7HE 1YNJK 2WB1H 3RZOF 4GZYE 4Y52F 5E18E 2VUMF 5M5XF 3I4NE 4YFNE 2JA6F 1TWHE 5C3EE 4YFXE 1ZYRE 3FKIF 3S1QF 4A3MF 1R9TF 5M5XE 3GTQE 4BY1F 4MEYE 4LK1E 3S1MF 2JA6E 5M3FF 1SMYE 4OIRE 4A93F 4G7OE 3FKIE 3S1QE 4A3ME 4AYBH 1R9TE 4BY1E 3CQZF 4C3IF 5M3MF 2E2HF 2JA7F 3HOZF 4A93E 4C2MF 2PMZH 3I4MF 2PMZK 2E2HE 5C4XE 3CQZE 4C3IE 3HOWE 3HOZE 4XLPE 4C2ME 3S15E 3I4ME 4LK0E 1TWAF 4BY7F 5TMFE 3RZDF 4OIOE 4A3LF 3H0GF 5BYHE 1I3QE 2NVYF 5IP7F 3S1NF 3S16E 2E2IF 3S17F 1TWAE 3RZDE 4A3LE 4BY7E 4A3GE 2A6HE 3H0GE 4A3FF 2NVYE 5IP7E 3S1NE 4YG2E 2E2IE 3S17E 3K7AF 3M4OF 4XSXE 4Y52E 2VUME 4A3FE 2JA5F 2A69E 2O5IE 3HOUF 3M4OE 5FLMF 4BXXF 2JA5E 3S1ME 5D4CE 2CW0E 4OIQE 5M3FE 4A3DF 4A3KF 2R92F 3GTPF 1I50F 5FLME 2JA7E 5M3ME 4BXXE 2A6EE 4G7ZE 5M5YF 1TWCF 4A3DE 3HKZH 4A3KE 3GTPE 1DZFA 1I50E 2R92E 3HKZK 3GTGF 5C4XF 3H3VF 3S2DF 5M5YE 4LLGE 1TWCE 5IYCF 3GTGE 1WCMF 1I6VE 2KRXA 4A3IF 2JA8F 3H3VG 5IPLE 4Q5SE 4LJZE 3HOYF 5C4JF 3S2DE 5M5WF 4KMUE 4XLNE 1Y1WF 1WCME 4A3IE 2O5JE 4C3HF 1EIKA 4Q4ZE 3HOYE 3S1RF 2NVQF 5M5WE 1K83F 1TWGF 4Y7NF 1Y1WE 1QKLA 5D4EE 3PO3F 4C3HE 4X6AF 1HQME 3GTLF 2R93F 3S1RE 5E17E 4ZH4E 3K7AE 2NVQE 3PO3E 1K83E 4Y7NE 4XSZE 5IP9F 4C3JF 2A68E 4X6AE 3M3YF 3GTLE 2R93E 2Y0SI 4OIPE 5IYDF 4KN7E 3HOUE 5FJ8F 4OINE 5IP9E 4C3JE 3WODE 3GTOF 3HOVF 2B63F 4BBRF 5IYDE 5FJ8E 2R7ZF 1YNNK 2WAQK 5IYBF 3GTMF 2YU9F 3HOVE 3GTOE 4YFKE 2B63E 5C3EF 4BBRE 2R7ZE 4KN4E 3GTKF 5IYBE 3GTJF 3GTME 2YU9E 1Y1VF 2Y0SH 3GTQF 3S2HF 2NVTF 4A3BF 5D4DE 5IYCE 3GTKE 2JA8E 3GTJE 3S2HE 1Y1VE 3DXJE 1TWFF 2BE5E 2NVXF 1I6HF 3PO2F 2NVTE 4A3BE 5C4JE 2E2JF 4AYBK 3HOWF 1I6HE 3PO2E 1TWFE 2NVXE 3HOXF 4JK1E 4MEXE 3S15F 1TWGE 2WB1I 2E2JE 1IW7E 4A3JF 4BBSF 5C44F 4QIWH 4QIWK 2PPBE 3HOXE 3EQLE
chains in the Genus database with same CATH topology
4BBSE 4A3JE 5C44E 3M3YE 3RZOE 2WAQH 4A3EE 3S14E 1SFOE 4A3CE 2WB1H 3I4NE 1TWHE 5C3EE 5M5XE 3GTQE 2JA6E 3FKIE 3S1QE 4A3ME 4AYBH 1R9TE 4BY1E 4A93E 2PMZH 2E2HE 5C4XE 3CQZE 4C3IE 3HOWE 3HOZE 4C2ME 3S15E 3I4ME 1I3QE 3S16E 1TWAE 3RZDE 4A3LE 4BY7E 4A3GE 3H0GE 2NVYE 5IP7E 3S1NE 2E2IE 3S17E 4Y52E 2VUME 4A3FE 3M4OE 2JA5E 3S1ME 5M3FE 5FLME 2JA7E 5M3ME 4BXXE 4A3DE 3HKZH 4A3KE 3GTPE 1DZFA 1I50E 2R92E 3H3VF 5M5YE 1TWCE 3GTGE 3S2DE 1WCME 4A3IE 1EIKA 3HOYE 5M5WE 1Y1WE 4C3HE 3S1RE 3K7AE 2NVQE 3PO3E 1K83E 4Y7NE 4X6AE 3GTLE 2R93E 3HOUE 5IP9E 4C3JE 5IYDE 5FJ8E 3HOVE 3GTOE 2B63E 4BBRE 2R7ZE 5IYBE 3GTME 2YU9E 2Y0SH 5IYCE 3GTKE 2JA8E 3GTJE 3S2HE 1Y1VE 2NVTE 4A3BE 5C4JE 1I6HE 3PO2E 1TWFE 2NVXE 1TWGE 2E2JE 4QIWH 3HOXE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BBS E;  4A3J E;  5C44 E;  3M3Y E;  3RZO E;  2WAQ H;  4A3E E;  3S14 E;  1SFO E;  4A3C E;  2WB1 H;  3I4N E;  1TWH E;  5C3E E;  5M5X E;  3GTQ E;  2JA6 E;  3FKI E;  3S1Q E;  4A3M E;  4AYB H;  1R9T E;  4BY1 E;  4A93 E;  2PMZ H;  2E2H E;  5C4X E;  3CQZ E;  4C3I E;  3HOW E;  3HOZ E;  4C2M E;  3S15 E;  3I4M E;  1I3Q E;  3S16 E;  1TWA E;  3RZD E;  4A3L E;  4BY7 E;  4A3G E;  3H0G E;  2NVY E;  5IP7 E;  3S1N E;  2E2I E;  3S17 E;  4Y52 E;  2VUM E;  4A3F E;  3M4O E;  2JA5 E;  3S1M E;  5M3F E;  5FLM E;  2JA7 E;  5M3M E;  4BXX E;  4A3D E;  3HKZ H;  4A3K E;  3GTP E;  1DZF A;  1I50 E;  2R92 E;  3H3V F;  5M5Y E;  1TWC E;  3GTG E;  3S2D E;  1WCM E;  4A3I E;  1EIK A;  3HOY E;  5M5W E;  1Y1W E;  4C3H E;  3S1R E;  3K7A E;  2NVQ E;  3PO3 E;  1K83 E;  4Y7N E;  4X6A E;  3GTL E;  2R93 E;  3HOU E;  5IP9 E;  4C3J E;  5IYD E;  5FJ8 E;  3HOV E;  3GTO E;  2B63 E;  4BBR E;  2R7Z E;  5IYB E;  3GTM E;  2YU9 E;  2Y0S H;  5IYC E;  3GTK E;  2JA8 E;  3GTJ E;  3S2H E;  1Y1V E;  2NVT E;  4A3B E;  5C4J E;  1I6H E;  3PO2 E;  1TWF E;  2NVX E;  1TWG E;  2E2J E;  4QIW H;  3HOX E; 
#chains in the Genus database with same CATH topology
 4A3E F;  4BBS E;  1I3Q F;  4A3J E;  5C44 E;  3S14 F;  3S16 F;  3M3Y E;  3RZO E;  1SFO F;  4A3C F;  4A3G F;  4MQ9 E;  2WAQ H;  5TMC E;  4A3E E;  3I4N F;  3S14 E;  1TWH F;  1SFO E;  4A3C E;  4G7H E;  1YNJ K;  2WB1 H;  3RZO F;  4GZY E;  4Y52 F;  5E18 E;  2VUM F;  5M5X F;  3I4N E;  4YFN E;  2JA6 F;  1TWH E;  5C3E E;  4YFX E;  1ZYR E;  3FKI F;  3S1Q F;  4A3M F;  1R9T F;  5M5X E;  3GTQ E;  4BY1 F;  4MEY E;  4LK1 E;  3S1M F;  2JA6 E;  5M3F F;  1SMY E;  4OIR E;  4A93 F;  4G7O E;  3FKI E;  3S1Q E;  4A3M E;  4AYB H;  1R9T E;  4BY1 E;  3CQZ F;  4C3I F;  5M3M F;  2E2H F;  2JA7 F;  3HOZ F;  4A93 E;  4C2M F;  2PMZ H;  3I4M F;  2PMZ K;  2E2H E;  5C4X E;  3CQZ E;  4C3I E;  3HOW E;  3HOZ E;  4XLP E;  4C2M E;  3S15 E;  3I4M E;  4LK0 E;  1TWA F;  4BY7 F;  5TMF E;  3RZD F;  4OIO E;  4A3L F;  3H0G F;  5BYH E;  1I3Q E;  2NVY F;  5IP7 F;  3S1N F;  3S16 E;  2E2I F;  3S17 F;  1TWA E;  3RZD E;  4A3L E;  4BY7 E;  4A3G E;  2A6H E;  3H0G E;  4A3F F;  2NVY E;  5IP7 E;  3S1N E;  4YG2 E;  2E2I E;  3S17 E;  3K7A F;  3M4O F;  4XSX E;  4Y52 E;  2VUM E;  4A3F E;  2JA5 F;  2A69 E;  2O5I E;  3HOU F;  3M4O E;  5FLM F;  4BXX F;  2JA5 E;  3S1M E;  5D4C E;  2CW0 E;  4OIQ E;  5M3F E;  4A3D F;  4A3K F;  2R92 F;  3GTP F;  1I50 F;  5FLM E;  2JA7 E;  5M3M E;  4BXX E;  2A6E E;  4G7Z E;  5M5Y F;  1TWC F;  4A3D E;  3HKZ H;  4A3K E;  3GTP E;  1DZF A;  1I50 E;  2R92 E;  3HKZ K;  3GTG F;  5C4X F;  3H3V F;  3S2D F;  5M5Y E;  4LLG E;  1TWC E;  5IYC F;  3GTG E;  1WCM F;  1I6V E;  2KRX A;  4A3I F;  2JA8 F;  3H3V G;  5IPL E;  4Q5S E;  4LJZ E;  3HOY F;  5C4J F;  3S2D E;  5M5W F;  4KMU E;  4XLN E;  1Y1W F;  1WCM E;  4A3I E;  2O5J E;  4C3H F;  1EIK A;  4Q4Z E;  3HOY E;  3S1R F;  2NVQ F;  5M5W E;  1K83 F;  1TWG F;  4Y7N F;  1Y1W E;  1QKL A;  5D4E E;  3PO3 F;  4C3H E;  4X6A F;  1HQM E;  3GTL F;  2R93 F;  3S1R E;  5E17 E;  4ZH4 E;  3K7A E;  2NVQ E;  3PO3 E;  1K83 E;  4Y7N E;  4XSZ E;  5IP9 F;  4C3J F;  2A68 E;  4X6A E;  3M3Y F;  3GTL E;  2R93 E;  2Y0S I;  4OIP E;  5IYD F;  4KN7 E;  3HOU E;  5FJ8 F;  4OIN E;  5IP9 E;  4C3J E;  3WOD E;  3GTO F;  3HOV F;  2B63 F;  4BBR F;  5IYD E;  5FJ8 E;  2R7Z F;  1YNN K;  2WAQ K;  5IYB F;  3GTM F;  2YU9 F;  3HOV E;  3GTO E;  4YFK E;  2B63 E;  5C3E F;  4BBR E;  2R7Z E;  4KN4 E;  3GTK F;  5IYB E;  3GTJ F;  3GTM E;  2YU9 E;  1Y1V F;  2Y0S H;  3GTQ F;  3S2H F;  2NVT F;  4A3B F;  5D4D E;  5IYC E;  3GTK E;  2JA8 E;  3GTJ E;  3S2H E;  1Y1V E;  3DXJ E;  1TWF F;  2BE5 E;  2NVX F;  1I6H F;  3PO2 F;  2NVT E;  4A3B E;  5C4J E;  2E2J F;  4AYB K;  3HOW F;  1I6H E;  3PO2 E;  1TWF E;  2NVX E;  3HOX F;  4JK1 E;  4MEX E;  3S15 F;  1TWG E;  2WB1 I;  2E2J E;  1IW7 E;  4A3J F;  4BBS F;  5C44 F;  4QIW H;  4QIW K;  2PPB E;  3HOX E;  3EQL E; 
#chains in the Genus database with same CATH homology
 4BBS E;  4A3J E;  5C44 E;  3M3Y E;  3RZO E;  2WAQ H;  4A3E E;  3S14 E;  1SFO E;  4A3C E;  2WB1 H;  3I4N E;  1TWH E;  5C3E E;  5M5X E;  3GTQ E;  2JA6 E;  3FKI E;  3S1Q E;  4A3M E;  4AYB H;  1R9T E;  4BY1 E;  4A93 E;  2PMZ H;  2E2H E;  5C4X E;  3CQZ E;  4C3I E;  3HOW E;  3HOZ E;  4C2M E;  3S15 E;  3I4M E;  1I3Q E;  3S16 E;  1TWA E;  3RZD E;  4A3L E;  4BY7 E;  4A3G E;  3H0G E;  2NVY E;  5IP7 E;  3S1N E;  2E2I E;  3S17 E;  4Y52 E;  2VUM E;  4A3F E;  3M4O E;  2JA5 E;  3S1M E;  5M3F E;  5FLM E;  2JA7 E;  5M3M E;  4BXX E;  4A3D E;  3HKZ H;  4A3K E;  3GTP E;  1DZF A;  1I50 E;  2R92 E;  3H3V F;  5M5Y E;  1TWC E;  3GTG E;  3S2D E;  1WCM E;  4A3I E;  1EIK A;  3HOY E;  5M5W E;  1Y1W E;  4C3H E;  3S1R E;  3K7A E;  2NVQ E;  3PO3 E;  1K83 E;  4Y7N E;  4X6A E;  3GTL E;  2R93 E;  3HOU E;  5IP9 E;  4C3J E;  5IYD E;  5FJ8 E;  3HOV E;  3GTO E;  2B63 E;  4BBR E;  2R7Z E;  5IYB E;  3GTM E;  2YU9 E;  2Y0S H;  5IYC E;  3GTK E;  2JA8 E;  3GTJ E;  3S2H E;  1Y1V E;  2NVT E;  4A3B E;  5C4J E;  1I6H E;  3PO2 E;  1TWF E;  2NVX E;  1TWG E;  2E2J E;  4QIW H;  3HOX E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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