1HQME

Crystal structure of thermus aquaticus core rna polymerase-includes complete structure with side-chains (except for disordered regions)-further refined from original deposition-contains additional sequence information
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
98
structure length
98
Chain Sequence
MAEPGIDKLFGMVDSKYRLTVVVAKRAQQLLRHRFKNTVLEPEERPKMRTLEGLYDDPNAVTWAMKELLTGRLFFGENLVPEDRLQKEMERLYPTEEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Bacterial RNA polymerase subunit omega and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly.
pubmed doi rcsb
molecule tags Transferase
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 16
structure length 98
sequence length 98
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2000-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 1hqmE00
4OIOE 2YU9F 3M4OF 3PO2F 4LLGE 4AYBK 4A3FF 3DXJE 5M5WF 3GTJF 2NVYF 2O5JE 2WB1I 5C4JF 4BY1F 2E2IF 1I6HF 5D4EE 3HOXF 2E2HF 4A93F 2R92F 4KMUE 5C44F 3FKIF 1SFOF 5IYBF 1Y1WF 4GZYE 1I50F 1Y1VF 4G7ZE 3S1RF 5IYDF 4A3MF 4A3KF 3S15F 4A3BF 3H0GF 5M3FF 4Q4ZE 3S2HF 2A6HE 3S1NF 2BE5E 4OIPE 4A3DF 1TWAF 4ZH4E 1QKLA 5IYCF 2NVXF 1HQME 4YG2E 4A3LF 5M5XF 4KN7E 1ZYRE 3HOUF 1YNNK 3CQZF 3HOZF 5E17E 2NVTF 4XLNE 1TWFF 4LJZE 5IP9F 2NVQF 2JA6F 3GTKF 3GTQF 1YNJK 1WCMF 2PMZK 4Y7NF 3HOYF 2R93F 5C4XF 1I6VE 4C3JF 3GTOF 3S14F 4Y52F 3GTPF 3S17F 4C3HF 3I4NF 3M3YF 3PO3F 2E2JF 4YFKE 2PPBE 3K7AF 4OIQE 3GTGF 4A3JF 4XSZE 4BBSF 4XSXE 4JK1E 5E18E 5IPLE 4OINE 4MEXE 5M3MF 4A3IF 4XLPE 2JA5F 4BBRF 4BY7F 1TWCF 3RZOF 1IW7E 1SMYE 5TMFE 5M5YF 3GTLF 1TWGF 4OIRE 3I4MF 4KN4E 4G7OE 4A3CF 3WODE 2B63F 2VUMF 3GTMF 4Q5SE 5IP7F 3S2DF 5D4CE 5FLMF 4A3GF 4MEYE 5BYHE 4LK0E 1K83F 1R9TF 4YFXE 4C3IF 5FJ8F 2O5IE 4A3EF 5C3EF 4C2MF 3S1QF 3HOVF 4X6AF 4MQ9E 3RZDF 2JA8F 1TWHF 2A69E 4G7HE 5TMCE 4LK1E 2A68E 4BXXF 3EQLE 4YFNE 2R7ZF 1I3QF 3S1MF 5D4DE 2CW0E 3S16F 2JA7F 3HKZK 2A6EE 3H3VG 2WAQK 2Y0SI 3HOWF
chains in the Genus database with same CATH superfamily
4OIOE 2YU9F 3M4OF 3PO2F 4X6AE 4A93E 2R92E 4LLGE 4AYBK 4A3FF 3DXJE 1TWHE 5M5WF 3GTJF 2NVYF 2JA8E 1SFOE 5IYBE 2WB1I 5C4JF 4BY1F 2O5JE 2E2IF 1Y1WE 1I6HF 4BXXE 5D4EE 1I50E 3HOXF 2E2HF 4A93F 3S1ME 2R92F 4KMUE 5C44F 3S15E 4A3BE 3FKIF 5M3FE 5IYBF 1SFOF 3H3VF 1Y1WF 4GZYE 3S2HE 1I50F 1Y1VF 4G7ZE 3S1RF 4A3DE 1TWAE 5IYDF 4A3MF 4A3KF 5IYCE 2YU9E 3M4OE 2Y0SH 3S15F 4A3BF 3H0GF 5M3FF 4Q4ZE 4A3LE 4QIWK 3S2HF 4A3FE 2A6HE 3HOUE 3CQZE 3HOZE 3S1NF 2BE5E 4OIPE 4A3DF 1TWAF 4ZH4E 1QKLA 5IYCF 2NVXF 3HOXE 2E2HE 1TWFE 1HQME 4YG2E 4A3LF 2NVQE 5C44E 5M5XF 4KN7E 1ZYRE 2KRXA 1YNNK 3CQZF 3FKIE 3HOUF 3GTKE 3GTQE 3HOZF 1WCME 5E17E 2NVTF 4XLNE 1Y1VE 3GTOE 3S14E 4Y52E 1TWFF 3S1RE 4LJZE 5IP9F 5IYDE 4A3ME 2NVQF 4A3KE 2JA6F 3I4NE 3M3YE 3H0GE 3GTKF 3GTQF 1YNJK 1WCMF 2PMZK 4Y7NF 3HOYF 2R93F 5C4XF 1I6VE 4C3JF 3GTOF 3S14F 3S1NE 4Y52F 3GTPF 3S17F 4A3JE 4C3HF 2NVXE 3I4NF 3M3YF 3PO3F 2E2JF 4BBSE 4YFKE 2PPBE 3HKZH 5M5XE 1DZFA 3K7AF 4OIQE 3GTGF 2WAQH 2WB1H 4A3JF 2NVTE 4XSZE 5M3ME 4A3IE 5IP9E 4BBSF 2JA5E 4XSXE 4AYBH 2JA6E 4JK1E 1TWCE 3RZOE 4Y7NE 3HOYE 5E18E 3GTLE 2R93E 5IPLE 4OINE 5C4XE 4C3JE 4MEXE 5M3MF 4A3IF 4XLPE 2JA5F 4BBRF 3GTPE 4BY7F 3S17E 4C3HE 2B63E 1TWCF 3GTME 3PO3E 5IP7E 2E2JE 3RZOF 3S2DE 1IW7E 1SMYE 5TMFE 5M5YF 3GTLF 1TWGF 5FLME 4OIRE 3K7AE 3I4MF 1K83E 3GTGE 4KN4E 4G7OE 4C3IE 4A3CF 3WODE 2B63F 5C3EE 2VUMF 3GTMF 4Q5SE 5IP7F 3S2DF 4QIWH 5D4CE 5FLMF 4A3GF 4BY1E 4MEYE 5BYHE 4LK0E 1K83F 3RZDE 1R9TF 4YFXE 4C3IF 5FJ8F 2O5IE 4A3EF 5C3EF 4C2MF 3S1QF 3HOVF 4X6AF 4MQ9E 4BBRE 2R7ZE 4BY7E 1I3QE 3S16E 5M5YE 3RZDF 1TWHF 2A69E 4G7HE 2JA8F 1TWGE 1EIKA 2JA7E 5TMCE 4LK1E 3I4ME 2A68E 4BXXF 3EQLE 4A3CE 4YFNE 2R7ZF 2VUME 1I3QF 3S1MF 5D4DE 2CW0E 3S16F 3HOWE 2PMZH 3PO2E 4A3GE 2JA7F 3S1QE 3HKZK 2A6EE 1R9TE 5M5WE 5FJ8E 2NVYE 3GTJE 3H3VG 5C4JE 4A3EE 4C2ME 2E2IE 2WAQK 2Y0SI 1I6HE 3HOWF 3HOVE
chains in the Genus database with same CATH topology
4OIOE 2YU9F 3M4OF 3PO2F 4LLGE 4AYBK 4A3FF 3DXJE 5M5WF 3GTJF 2NVYF 2O5JE 2WB1I 5C4JF 4BY1F 2E2IF 1I6HF 5D4EE 3HOXF 2E2HF 4A93F 2R92F 4KMUE 5C44F 3FKIF 1SFOF 5IYBF 1Y1WF 4GZYE 1I50F 1Y1VF 4G7ZE 3S1RF 5IYDF 4A3MF 4A3KF 3S15F 4A3BF 3H0GF 5M3FF 4Q4ZE 4QIWK 3S2HF 2A6HE 3S1NF 2BE5E 4OIPE 4A3DF 1TWAF 4ZH4E 1QKLA 5IYCF 2NVXF 1HQME 4YG2E 4A3LF 5M5XF 4KN7E 1ZYRE 2KRXA 1YNNK 3CQZF 3HOUF 3HOZF 5E17E 2NVTF 4XLNE 1TWFF 4LJZE 5IP9F 2NVQF 2JA6F 3GTKF 3GTQF 1YNJK 1WCMF 2PMZK 4Y7NF 3HOYF 2R93F 5C4XF 1I6VE 4C3JF 3GTOF 3S14F 4Y52F 3GTPF 3S17F 4C3HF 3I4NF 3M3YF 3PO3F 2E2JF 4YFKE 2PPBE 3K7AF 4OIQE 3GTGF 4A3JF 4XSZE 4BBSF 4XSXE 4JK1E 5E18E 5IPLE 4OINE 4MEXE 5M3MF 4A3IF 4XLPE 2JA5F 4BBRF 4BY7F 1TWCF 3RZOF 1IW7E 1SMYE 5TMFE 5M5YF 3GTLF 1TWGF 4OIRE 3I4MF 4KN4E 4G7OE 4A3CF 3WODE 2B63F 2VUMF 3GTMF 4Q5SE 5IP7F 3S2DF 5D4CE 5FLMF 4A3GF 4MEYE 5BYHE 4LK0E 1K83F 1R9TF 4YFXE 4C3IF 5FJ8F 2O5IE 4A3EF 5C3EF 4C2MF 3S1QF 3HOVF 4X6AF 4MQ9E 3RZDF 2JA8F 1TWHF 2A69E 4G7HE 5TMCE 4LK1E 2A68E 4BXXF 3EQLE 4YFNE 2R7ZF 1I3QF 3S1MF 5D4DE 2CW0E 3S16F 2JA7F 3HKZK 2A6EE 3H3VG 2WAQK 2Y0SI 3HOWF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OIO E;  2YU9 F;  3M4O F;  3PO2 F;  4LLG E;  4AYB K;  4A3F F;  3DXJ E;  5M5W F;  3GTJ F;  2NVY F;  2O5J E;  2WB1 I;  5C4J F;  4BY1 F;  2E2I F;  1I6H F;  5D4E E;  3HOX F;  2E2H F;  4A93 F;  2R92 F;  4KMU E;  5C44 F;  3FKI F;  1SFO F;  5IYB F;  1Y1W F;  4GZY E;  1I50 F;  1Y1V F;  4G7Z E;  3S1R F;  5IYD F;  4A3M F;  4A3K F;  3S15 F;  4A3B F;  3H0G F;  5M3F F;  4Q4Z E;  3S2H F;  2A6H E;  3S1N F;  2BE5 E;  4OIP E;  4A3D F;  1TWA F;  4ZH4 E;  1QKL A;  5IYC F;  2NVX F;  1HQM E;  4YG2 E;  4A3L F;  5M5X F;  4KN7 E;  1ZYR E;  3HOU F;  1YNN K;  3CQZ F;  3HOZ F;  5E17 E;  2NVT F;  4XLN E;  1TWF F;  4LJZ E;  5IP9 F;  2NVQ F;  2JA6 F;  3GTK F;  3GTQ F;  1YNJ K;  1WCM F;  2PMZ K;  4Y7N F;  3HOY F;  2R93 F;  5C4X F;  1I6V E;  4C3J F;  3GTO F;  3S14 F;  4Y52 F;  3GTP F;  3S17 F;  4C3H F;  3I4N F;  3M3Y F;  3PO3 F;  2E2J F;  4YFK E;  2PPB E;  3K7A F;  4OIQ E;  3GTG F;  4A3J F;  4XSZ E;  4BBS F;  4XSX E;  4JK1 E;  5E18 E;  5IPL E;  4OIN E;  4MEX E;  5M3M F;  4A3I F;  4XLP E;  2JA5 F;  4BBR F;  4BY7 F;  1TWC F;  3RZO F;  1IW7 E;  1SMY E;  5TMF E;  5M5Y F;  3GTL F;  1TWG F;  4OIR E;  3I4M F;  4KN4 E;  4G7O E;  4A3C F;  3WOD E;  2B63 F;  2VUM F;  3GTM F;  4Q5S E;  5IP7 F;  3S2D F;  5D4C E;  5FLM F;  4A3G F;  4MEY E;  5BYH E;  4LK0 E;  1K83 F;  1R9T F;  4YFX E;  4C3I F;  5FJ8 F;  2O5I E;  4A3E F;  5C3E F;  4C2M F;  3S1Q F;  3HOV F;  4X6A F;  4MQ9 E;  3RZD F;  2JA8 F;  1TWH F;  2A69 E;  4G7H E;  5TMC E;  4LK1 E;  2A68 E;  4BXX F;  3EQL E;  4YFN E;  2R7Z F;  1I3Q F;  3S1M F;  5D4D E;  2CW0 E;  3S16 F;  2JA7 F;  3HKZ K;  2A6E E;  3H3V G;  2WAQ K;  2Y0S I;  3HOW F; 
#chains in the Genus database with same CATH topology
 4OIO E;  2YU9 F;  3M4O F;  3PO2 F;  4X6A E;  4A93 E;  2R92 E;  4LLG E;  4AYB K;  4A3F F;  3DXJ E;  1TWH E;  5M5W F;  3GTJ F;  2NVY F;  2JA8 E;  1SFO E;  5IYB E;  2WB1 I;  5C4J F;  4BY1 F;  2O5J E;  2E2I F;  1Y1W E;  1I6H F;  4BXX E;  5D4E E;  1I50 E;  3HOX F;  2E2H F;  4A93 F;  3S1M E;  2R92 F;  4KMU E;  5C44 F;  3S15 E;  4A3B E;  3FKI F;  5M3F E;  5IYB F;  1SFO F;  3H3V F;  1Y1W F;  4GZY E;  3S2H E;  1I50 F;  1Y1V F;  4G7Z E;  3S1R F;  4A3D E;  1TWA E;  5IYD F;  4A3M F;  4A3K F;  5IYC E;  2YU9 E;  3M4O E;  2Y0S H;  3S15 F;  4A3B F;  3H0G F;  5M3F F;  4Q4Z E;  4A3L E;  4QIW K;  3S2H F;  4A3F E;  2A6H E;  3HOU E;  3CQZ E;  3HOZ E;  3S1N F;  2BE5 E;  4OIP E;  4A3D F;  1TWA F;  4ZH4 E;  1QKL A;  5IYC F;  2NVX F;  3HOX E;  2E2H E;  1TWF E;  1HQM E;  4YG2 E;  4A3L F;  2NVQ E;  5C44 E;  5M5X F;  4KN7 E;  1ZYR E;  2KRX A;  1YNN K;  3CQZ F;  3FKI E;  3HOU F;  3GTK E;  3GTQ E;  3HOZ F;  1WCM E;  5E17 E;  2NVT F;  4XLN E;  1Y1V E;  3GTO E;  3S14 E;  4Y52 E;  1TWF F;  3S1R E;  4LJZ E;  5IP9 F;  5IYD E;  4A3M E;  2NVQ F;  4A3K E;  2JA6 F;  3I4N E;  3M3Y E;  3H0G E;  3GTK F;  3GTQ F;  1YNJ K;  1WCM F;  2PMZ K;  4Y7N F;  3HOY F;  2R93 F;  5C4X F;  1I6V E;  4C3J F;  3GTO F;  3S14 F;  3S1N E;  4Y52 F;  3GTP F;  3S17 F;  4A3J E;  4C3H F;  2NVX E;  3I4N F;  3M3Y F;  3PO3 F;  2E2J F;  4BBS E;  4YFK E;  2PPB E;  3HKZ H;  5M5X E;  1DZF A;  3K7A F;  4OIQ E;  3GTG F;  2WAQ H;  2WB1 H;  4A3J F;  2NVT E;  4XSZ E;  5M3M E;  4A3I E;  5IP9 E;  4BBS F;  2JA5 E;  4XSX E;  4AYB H;  2JA6 E;  4JK1 E;  1TWC E;  3RZO E;  4Y7N E;  3HOY E;  5E18 E;  3GTL E;  2R93 E;  5IPL E;  4OIN E;  5C4X E;  4C3J E;  4MEX E;  5M3M F;  4A3I F;  4XLP E;  2JA5 F;  4BBR F;  3GTP E;  4BY7 F;  3S17 E;  4C3H E;  2B63 E;  1TWC F;  3GTM E;  3PO3 E;  5IP7 E;  2E2J E;  3RZO F;  3S2D E;  1IW7 E;  1SMY E;  5TMF E;  5M5Y F;  3GTL F;  1TWG F;  5FLM E;  4OIR E;  3K7A E;  3I4M F;  1K83 E;  3GTG E;  4KN4 E;  4G7O E;  4C3I E;  4A3C F;  3WOD E;  2B63 F;  5C3E E;  2VUM F;  3GTM F;  4Q5S E;  5IP7 F;  3S2D F;  4QIW H;  5D4C E;  5FLM F;  4A3G F;  4BY1 E;  4MEY E;  5BYH E;  4LK0 E;  1K83 F;  3RZD E;  1R9T F;  4YFX E;  4C3I F;  5FJ8 F;  2O5I E;  4A3E F;  5C3E F;  4C2M F;  3S1Q F;  3HOV F;  4X6A F;  4MQ9 E;  4BBR E;  2R7Z E;  4BY7 E;  1I3Q E;  3S16 E;  5M5Y E;  3RZD F;  1TWH F;  2A69 E;  4G7H E;  2JA8 F;  1TWG E;  1EIK A;  2JA7 E;  5TMC E;  4LK1 E;  3I4M E;  2A68 E;  4BXX F;  3EQL E;  4A3C E;  4YFN E;  2R7Z F;  2VUM E;  1I3Q F;  3S1M F;  5D4D E;  2CW0 E;  3S16 F;  3HOW E;  2PMZ H;  3PO2 E;  4A3G E;  2JA7 F;  3S1Q E;  3HKZ K;  2A6E E;  1R9T E;  5M5W E;  5FJ8 E;  2NVY E;  3GTJ E;  3H3V G;  5C4J E;  4A3E E;  4C2M E;  2E2I E;  2WAQ K;  2Y0S I;  1I6H E;  3HOW F;  3HOV E; 
#chains in the Genus database with same CATH homology
 4OIO E;  2YU9 F;  3M4O F;  3PO2 F;  4LLG E;  4AYB K;  4A3F F;  3DXJ E;  5M5W F;  3GTJ F;  2NVY F;  2O5J E;  2WB1 I;  5C4J F;  4BY1 F;  2E2I F;  1I6H F;  5D4E E;  3HOX F;  2E2H F;  4A93 F;  2R92 F;  4KMU E;  5C44 F;  3FKI F;  1SFO F;  5IYB F;  1Y1W F;  4GZY E;  1I50 F;  1Y1V F;  4G7Z E;  3S1R F;  5IYD F;  4A3M F;  4A3K F;  3S15 F;  4A3B F;  3H0G F;  5M3F F;  4Q4Z E;  4QIW K;  3S2H F;  2A6H E;  3S1N F;  2BE5 E;  4OIP E;  4A3D F;  1TWA F;  4ZH4 E;  1QKL A;  5IYC F;  2NVX F;  1HQM E;  4YG2 E;  4A3L F;  5M5X F;  4KN7 E;  1ZYR E;  2KRX A;  1YNN K;  3CQZ F;  3HOU F;  3HOZ F;  5E17 E;  2NVT F;  4XLN E;  1TWF F;  4LJZ E;  5IP9 F;  2NVQ F;  2JA6 F;  3GTK F;  3GTQ F;  1YNJ K;  1WCM F;  2PMZ K;  4Y7N F;  3HOY F;  2R93 F;  5C4X F;  1I6V E;  4C3J F;  3GTO F;  3S14 F;  4Y52 F;  3GTP F;  3S17 F;  4C3H F;  3I4N F;  3M3Y F;  3PO3 F;  2E2J F;  4YFK E;  2PPB E;  3K7A F;  4OIQ E;  3GTG F;  4A3J F;  4XSZ E;  4BBS F;  4XSX E;  4JK1 E;  5E18 E;  5IPL E;  4OIN E;  4MEX E;  5M3M F;  4A3I F;  4XLP E;  2JA5 F;  4BBR F;  4BY7 F;  1TWC F;  3RZO F;  1IW7 E;  1SMY E;  5TMF E;  5M5Y F;  3GTL F;  1TWG F;  4OIR E;  3I4M F;  4KN4 E;  4G7O E;  4A3C F;  3WOD E;  2B63 F;  2VUM F;  3GTM F;  4Q5S E;  5IP7 F;  3S2D F;  5D4C E;  5FLM F;  4A3G F;  4MEY E;  5BYH E;  4LK0 E;  1K83 F;  1R9T F;  4YFX E;  4C3I F;  5FJ8 F;  2O5I E;  4A3E F;  5C3E F;  4C2M F;  3S1Q F;  3HOV F;  4X6A F;  4MQ9 E;  3RZD F;  2JA8 F;  1TWH F;  2A69 E;  4G7H E;  5TMC E;  4LK1 E;  2A68 E;  4BXX F;  3EQL E;  4YFN E;  2R7Z F;  1I3Q F;  3S1M F;  5D4D E;  2CW0 E;  3S16 F;  2JA7 F;  3HKZ K;  2A6E E;  3H3V G;  2WAQ K;  2Y0S I;  3HOW F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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