1I6HE

Rna polymerase ii elongation complex
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription/dna-rna hybrid
source organism Saccharomyces cerevisiae
publication title Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution.
pubmed doi rcsb
molecule keywords 5'-D(P*AP*AP*AP*TP*GP*CP*CP*TP*GP*GP*TP*CP*T)-3'
total genus 54
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2001-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 1i6hE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 1i6hE02
3S1ME 1Y1VE 5IYBE 3M3YE 4BY7E 5FLME 3S2HE 2YU9E 3GTME 4A3GE 2VUME 5M5WE 5IP9E 2PMZH 3HOVE 2R93E 4C3HE 3HOYE 3S1RE 2NVQE 3S15E 2JA5E 2JA8E 1I50E 5C4XE 2E2HE 3I4NE 3K7AE 1Y1WE 4A93E 3S1NE 5M5YE 4A3DE 1TWGE 4A3EE 2NVYE 3GTKE 3S1QE 4A3CE 4X6AE 3HOUE 3FKIE 3CQZE 4AYBH 5IP7E 4A3LE 3GTLE 5FJ8E 5IYDE 4A3IE 2E2IE 2R92E 2WAQH 5M5XE 4QIWH 4BBSE 3PO2E 3GTQE 1K83E 1R9TE 3S17E 5M3FE 4A3BE 3GTOE 5C4JE 3S14E 4A3JE 2B63E 3GTJE 3HOZE 1TWHE 4BXXE 2R7ZE 3PO3E 2JA7E 1TWAE 2WB1H 3HOWE 1I3QE 3H0GE 3H3VF 4Y7NE 4BY1E 4C2ME 4A3KE 2E2JE 1WCME 4Y52E 1DZFA 4A3FE 1I6HE 3GTGE 1EIKA 1TWCE 5C44E 3HOXE 2Y0SH 4C3IE 4A3ME 3GTPE 1SFOE 3M4OE 3I4ME 3S2DE 3RZDE 3HKZH 4C3JE 3S16E 2NVTE 2JA6E 3RZOE 5IYCE 4BBRE 5M3ME 1TWFE 5C3EE 2NVXE
chains in the Genus database with same CATH superfamily
5C4XF 2E2HF 3S1ME 1K83F 3WODE 1R9TF 3S17F 1Y1VE 1Y1WF 5M3FF 4A93F 3GTOF 4JK1E 5C4JF 3S1NF 5IYBE 3M3YE 5TMCE 4A3JF 4A3DF 2B63F 3HOZF 1TWGF 1TWHF 4BY7E 5FLME 3S2HE 2YU9E 1SMYE 3GTKF 3PO3F 3GTME 4A3GE 1YNNK 3DXJE 2JA7F 2VUME 5M5WE 5IP9E 4X6AF 4ZH4E 3FKIF 5E18E 3CQZF 3HOWF 1I3QF 3H0GF 2PMZH 5IP7F 2Y0SI 4Y7NF 4BY1F 3HKZK 3HOVE 2R93E 4MEXE 2R92F 1IW7E 4C3HE 3HOYE 3S1RE 4A3KF 5BYHE 2NVQE 3S15E 1WCMF 3PO2F 1QKLA 4OIRE 2JA5E 2JA8E 1I50E 4LLGE 4A3FF 5C4XE 2E2HE 4KN7E 1I6HF 3GTGF 3I4NE 3K7AE 1Y1WE 4Q5SE 4A93E 4YFKE 3S1NE 1ZYRE 4A3BF 3HOXF 3S14F 5M5YE 4A3DE 3GTJF 1TWGE 2A6EE 4C3IF 4BXXF 4A3EE 2NVYE 3GTPF 1SFOF 2A6HE 2R7ZF 1I6VE 3M4OF 3GTKE 3I4MF 4YFXE 3S2DF 3RZDF 2A69E 3S1QE 1TWAF 4A3CE 4OINE 4X6AE 3HOUE 3FKIE 4C3JF 2O5IE 3CQZE 4AYBH 2JA8F 2JA6F 3RZOF 5IP7E 5IYCF 2PMZK 4A3LE 3GTLE 4BBRF 5FJ8E 5IYDE 4KN4E 4G7HE 4A3IE 2CW0E 2E2IE 2R92E 1TWFF 4C2MF 5D4EE 5C3EF 2NVXF 2WAQH 5M5XE 2E2JF 4QIWH 4BBSE 3PO2E 1Y1VF 4QIWK 4Y52F 3GTQE 5D4CE 4G7ZE 5IYBF 3M3YF 1K83E 1R9TE 3S17E 4BY7F 5FLMF 5M3FE 3S2HF 4A3BE 3GTOE 1TWCF 5C4JE 5C44F 3S14E 2YU9F 2O5JE 4A3JE 2B63E 3GTJE 3HOZE 4A3GF 1TWHE 1HQME 2VUMF 4BXXE 4A3MF 5M5WF 2R7ZE 2BE5E 2A68E 3PO3E 2JA7E 1TWAE 2WB1H 4Q4ZE 5IPLE 2KRXA 3HOVF 2R93F 3S16F 3HOWE 2NVTF 1I3QE 4AYBK 3H0GE 3H3VF 3HOYF 3S1RF 4Y7NE 5M3MF 4BY1E 4G7OE 2NVQF 4XLNE 4C2ME 3H3VG 1I50F 2JA5F 4YG2E 2WAQK 4MQ9E 4A3KE 2E2JE 3I4NF 1WCME 3K7AF 2PPBE 3S1MF 4Y52E 1DZFA 4LK1E 4A3FE 5M5YF 4LJZE 1I6HE 3GTGE 3EQLE 1EIKA 4A3EF 1TWCE 5C44E 2NVYF 3HOXE 4XSZE 5D4DE 2Y0SH 4GZYE 4C3IE 3GTMF 3S1QF 4A3ME 4A3CF 5E17E 4KMUE 5IP9F 5TMFE 3HOUF 3GTPE 1SFOE 3M4OE 3I4ME 4OIPE 3S2DE 3RZDE 4MEYE 4XSXE 1YNJK 3HKZH 3GTLF 5FJ8F 5IYDF 4A3LF 4A3IF 4C3JE 2E2IF 4OIOE 3S16E 2NVTE 4OIQE 2JA6E 3RZOE 5M5XF 4YFNE 4XLPE 4C3HF 5IYCE 4BBRE 5M3ME 3S15F 4BBSF 2WB1I 1TWFE 4LK0E 3GTQF 5C3EE 2NVXE
chains in the Genus database with same CATH topology
3S1ME 1Y1VE 5IYBE 3M3YE 4BY7E 5FLME 3S2HE 2YU9E 3GTME 4A3GE 2VUME 5M5WE 5IP9E 2PMZH 3HOVE 2R93E 4C3HE 3HOYE 3S1RE 2NVQE 3S15E 2JA5E 2JA8E 1I50E 5C4XE 2E2HE 3I4NE 3K7AE 1Y1WE 4A93E 3S1NE 5M5YE 4A3DE 1TWGE 4A3EE 2NVYE 3GTKE 3S1QE 4A3CE 4X6AE 3HOUE 3FKIE 3CQZE 4AYBH 5IP7E 4A3LE 3GTLE 5FJ8E 5IYDE 4A3IE 2E2IE 2R92E 2WAQH 5M5XE 4QIWH 4BBSE 3PO2E 3GTQE 1K83E 1R9TE 3S17E 5M3FE 4A3BE 3GTOE 5C4JE 3S14E 4A3JE 2B63E 3GTJE 3HOZE 1TWHE 4BXXE 2R7ZE 3PO3E 2JA7E 1TWAE 2WB1H 3HOWE 1I3QE 3H0GE 3H3VF 4Y7NE 4BY1E 4C2ME 4A3KE 2E2JE 1WCME 4Y52E 1DZFA 4A3FE 1I6HE 3GTGE 1EIKA 1TWCE 5C44E 3HOXE 2Y0SH 4C3IE 4A3ME 3GTPE 1SFOE 3M4OE 3I4ME 3S2DE 3RZDE 3HKZH 4C3JE 3S16E 2NVTE 2JA6E 3RZOE 5IYCE 4BBRE 5M3ME 1TWFE 5C3EE 2NVXE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S1M E;  1Y1V E;  5IYB E;  3M3Y E;  4BY7 E;  5FLM E;  3S2H E;  2YU9 E;  3GTM E;  4A3G E;  2VUM E;  5M5W E;  5IP9 E;  2PMZ H;  3HOV E;  2R93 E;  4C3H E;  3HOY E;  3S1R E;  2NVQ E;  3S15 E;  2JA5 E;  2JA8 E;  1I50 E;  5C4X E;  2E2H E;  3I4N E;  3K7A E;  1Y1W E;  4A93 E;  3S1N E;  5M5Y E;  4A3D E;  1TWG E;  4A3E E;  2NVY E;  3GTK E;  3S1Q E;  4A3C E;  4X6A E;  3HOU E;  3FKI E;  3CQZ E;  4AYB H;  5IP7 E;  4A3L E;  3GTL E;  5FJ8 E;  5IYD E;  4A3I E;  2E2I E;  2R92 E;  2WAQ H;  5M5X E;  4QIW H;  4BBS E;  3PO2 E;  3GTQ E;  1K83 E;  1R9T E;  3S17 E;  5M3F E;  4A3B E;  3GTO E;  5C4J E;  3S14 E;  4A3J E;  2B63 E;  3GTJ E;  3HOZ E;  1TWH E;  4BXX E;  2R7Z E;  3PO3 E;  2JA7 E;  1TWA E;  2WB1 H;  3HOW E;  1I3Q E;  3H0G E;  3H3V F;  4Y7N E;  4BY1 E;  4C2M E;  4A3K E;  2E2J E;  1WCM E;  4Y52 E;  1DZF A;  4A3F E;  1I6H E;  3GTG E;  1EIK A;  1TWC E;  5C44 E;  3HOX E;  2Y0S H;  4C3I E;  4A3M E;  3GTP E;  1SFO E;  3M4O E;  3I4M E;  3S2D E;  3RZD E;  3HKZ H;  4C3J E;  3S16 E;  2NVT E;  2JA6 E;  3RZO E;  5IYC E;  4BBR E;  5M3M E;  1TWF E;  5C3E E;  2NVX E; 
#chains in the Genus database with same CATH topology
 5C4X F;  2E2H F;  3S1M E;  1K83 F;  3WOD E;  1R9T F;  3S17 F;  1Y1V E;  1Y1W F;  5M3F F;  4A93 F;  3GTO F;  4JK1 E;  5C4J F;  3S1N F;  5IYB E;  3M3Y E;  5TMC E;  4A3J F;  4A3D F;  2B63 F;  3HOZ F;  1TWG F;  1TWH F;  4BY7 E;  5FLM E;  3S2H E;  2YU9 E;  1SMY E;  3GTK F;  3PO3 F;  3GTM E;  4A3G E;  1YNN K;  3DXJ E;  2JA7 F;  2VUM E;  5M5W E;  5IP9 E;  4X6A F;  4ZH4 E;  3FKI F;  5E18 E;  3CQZ F;  3HOW F;  1I3Q F;  3H0G F;  2PMZ H;  5IP7 F;  2Y0S I;  4Y7N F;  4BY1 F;  3HKZ K;  3HOV E;  2R93 E;  4MEX E;  2R92 F;  1IW7 E;  4C3H E;  3HOY E;  3S1R E;  4A3K F;  5BYH E;  2NVQ E;  3S15 E;  1WCM F;  3PO2 F;  1QKL A;  4OIR E;  2JA5 E;  2JA8 E;  1I50 E;  4LLG E;  4A3F F;  5C4X E;  2E2H E;  4KN7 E;  1I6H F;  3GTG F;  3I4N E;  3K7A E;  1Y1W E;  4Q5S E;  4A93 E;  4YFK E;  3S1N E;  1ZYR E;  4A3B F;  3HOX F;  3S14 F;  5M5Y E;  4A3D E;  3GTJ F;  1TWG E;  2A6E E;  4C3I F;  4BXX F;  4A3E E;  2NVY E;  3GTP F;  1SFO F;  2A6H E;  2R7Z F;  1I6V E;  3M4O F;  3GTK E;  3I4M F;  4YFX E;  3S2D F;  3RZD F;  2A69 E;  3S1Q E;  1TWA F;  4A3C E;  4OIN E;  4X6A E;  3HOU E;  3FKI E;  4C3J F;  2O5I E;  3CQZ E;  4AYB H;  2JA8 F;  2JA6 F;  3RZO F;  5IP7 E;  5IYC F;  2PMZ K;  4A3L E;  3GTL E;  4BBR F;  5FJ8 E;  5IYD E;  4KN4 E;  4G7H E;  4A3I E;  2CW0 E;  2E2I E;  2R92 E;  1TWF F;  4C2M F;  5D4E E;  5C3E F;  2NVX F;  2WAQ H;  5M5X E;  2E2J F;  4QIW H;  4BBS E;  3PO2 E;  1Y1V F;  4QIW K;  4Y52 F;  3GTQ E;  5D4C E;  4G7Z E;  5IYB F;  3M3Y F;  1K83 E;  1R9T E;  3S17 E;  4BY7 F;  5FLM F;  5M3F E;  3S2H F;  4A3B E;  3GTO E;  1TWC F;  5C4J E;  5C44 F;  3S14 E;  2YU9 F;  2O5J E;  4A3J E;  2B63 E;  3GTJ E;  3HOZ E;  4A3G F;  1TWH E;  1HQM E;  2VUM F;  4BXX E;  4A3M F;  5M5W F;  2R7Z E;  2BE5 E;  2A68 E;  3PO3 E;  2JA7 E;  1TWA E;  2WB1 H;  4Q4Z E;  5IPL E;  2KRX A;  3HOV F;  2R93 F;  3S16 F;  3HOW E;  2NVT F;  1I3Q E;  4AYB K;  3H0G E;  3H3V F;  3HOY F;  3S1R F;  4Y7N E;  5M3M F;  4BY1 E;  4G7O E;  2NVQ F;  4XLN E;  4C2M E;  3H3V G;  1I50 F;  2JA5 F;  4YG2 E;  2WAQ K;  4MQ9 E;  4A3K E;  2E2J E;  3I4N F;  1WCM E;  3K7A F;  2PPB E;  3S1M F;  4Y52 E;  1DZF A;  4LK1 E;  4A3F E;  5M5Y F;  4LJZ E;  1I6H E;  3GTG E;  3EQL E;  1EIK A;  4A3E F;  1TWC E;  5C44 E;  2NVY F;  3HOX E;  4XSZ E;  5D4D E;  2Y0S H;  4GZY E;  4C3I E;  3GTM F;  3S1Q F;  4A3M E;  4A3C F;  5E17 E;  4KMU E;  5IP9 F;  5TMF E;  3HOU F;  3GTP E;  1SFO E;  3M4O E;  3I4M E;  4OIP E;  3S2D E;  3RZD E;  4MEY E;  4XSX E;  1YNJ K;  3HKZ H;  3GTL F;  5FJ8 F;  5IYD F;  4A3L F;  4A3I F;  4C3J E;  2E2I F;  4OIO E;  3S16 E;  2NVT E;  4OIQ E;  2JA6 E;  3RZO E;  5M5X F;  4YFN E;  4XLP E;  4C3H F;  5IYC E;  4BBR E;  5M3M E;  3S15 F;  4BBS F;  2WB1 I;  1TWF E;  4LK0 E;  3GTQ F;  5C3E E;  2NVX E; 
#chains in the Genus database with same CATH homology
 3S1M E;  1Y1V E;  5IYB E;  3M3Y E;  4BY7 E;  5FLM E;  3S2H E;  2YU9 E;  3GTM E;  4A3G E;  2VUM E;  5M5W E;  5IP9 E;  2PMZ H;  3HOV E;  2R93 E;  4C3H E;  3HOY E;  3S1R E;  2NVQ E;  3S15 E;  2JA5 E;  2JA8 E;  1I50 E;  5C4X E;  2E2H E;  3I4N E;  3K7A E;  1Y1W E;  4A93 E;  3S1N E;  5M5Y E;  4A3D E;  1TWG E;  4A3E E;  2NVY E;  3GTK E;  3S1Q E;  4A3C E;  4X6A E;  3HOU E;  3FKI E;  3CQZ E;  4AYB H;  5IP7 E;  4A3L E;  3GTL E;  5FJ8 E;  5IYD E;  4A3I E;  2E2I E;  2R92 E;  2WAQ H;  5M5X E;  4QIW H;  4BBS E;  3PO2 E;  3GTQ E;  1K83 E;  1R9T E;  3S17 E;  5M3F E;  4A3B E;  3GTO E;  5C4J E;  3S14 E;  4A3J E;  2B63 E;  3GTJ E;  3HOZ E;  1TWH E;  4BXX E;  2R7Z E;  3PO3 E;  2JA7 E;  1TWA E;  2WB1 H;  3HOW E;  1I3Q E;  3H0G E;  3H3V F;  4Y7N E;  4BY1 E;  4C2M E;  4A3K E;  2E2J E;  1WCM E;  4Y52 E;  1DZF A;  4A3F E;  1I6H E;  3GTG E;  1EIK A;  1TWC E;  5C44 E;  3HOX E;  2Y0S H;  4C3I E;  4A3M E;  3GTP E;  1SFO E;  3M4O E;  3I4M E;  3S2D E;  3RZD E;  3HKZ H;  4C3J E;  3S16 E;  2NVT E;  2JA6 E;  3RZO E;  5IYC E;  4BBR E;  5M3M E;  1TWF E;  5C3E E;  2NVX E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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