1I6HE

Rna polymerase ii elongation complex
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution.
pubmed doi rcsb
molecule tags Transcription/dna-rna hybrid
source organism Saccharomyces cerevisiae
molecule keywords 5'-D(P*AP*AP*AP*TP*GP*CP*CP*TP*GP*GP*TP*CP*T)-3'
total genus 54
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2001-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 1i6hE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 1i6hE02
2JA7E 4A3LE 1TWGE 2WAQH 4A3FE 3CQZE 3S2DE 2VUME 1TWHE 5M3ME 1I6HE 1TWFE 5M5XE 3GTQE 3S1QE 4X6AE 4C3JE 5M5WE 4C2ME 5M5YE 3HOZE 2Y0SH 1TWCE 4BBRE 1DZFA 1WCME 5IYBE 3I4NE 3HOYE 3GTPE 3HOWE 4A3BE 4Y7NE 3HOVE 2WB1H 4C3IE 2R93E 1Y1VE 5IP7E 4A3ME 2JA6E 1I3QE 2NVYE 1TWAE 3HOUE 3S1NE 3K7AE 3H0GE 2NVXE 2B63E 4A3IE 4A3JE 5C4XE 3H3VF 5IYDE 4BXXE 3HKZH 4BY7E 5M3FE 1Y1WE 3S17E 2E2JE 3M4OE 5IP9E 3GTME 3PO3E 1I50E 3GTOE 5FLME 5C44E 4A3CE 3PO2E 2R7ZE 5FJ8E 4A3KE 3S2HE 3GTGE 4BBSE 3HOXE 3FKIE 2NVQE 4A3EE 1R9TE 4Y52E 2JA5E 5IYCE 2JA8E 5C4JE 4AYBH 3S1ME 1EIKA 2E2HE 3S1RE 1K83E 4A3GE 1SFOE 3M3YE 3GTKE 3RZOE 2E2IE 4BY1E 3S14E 3S15E 3GTJE 2NVTE 2PMZH 3S16E 4A93E 4C3HE 3GTLE 3I4ME 2R92E 5C3EE 3RZDE 4A3DE 2YU9E 4QIWH
chains in the Genus database with same CATH superfamily
2JA7E 4A3LE 1TWGE 4Q4ZE 2WAQH 3WODE 3GTJF 4A3FE 4YFNE 2WB1I 2PPBE 2NVTF 4C2MF 3CQZE 3S2DE 4AYBK 3HOZF 1TWCF 4LLGE 2VUME 1TWHE 4MEXE 5M3ME 1I6HE 1WCMF 5C3EF 4X6AF 5IYBF 1TWFE 3HOYF 3HOWF 3RZDF 5M5XE 4A3BF 3GTQE 3S1QE 4X6AE 4Y7NF 4C3JE 5M5WE 4YG2E 3HOVF 4C3IF 4KN7E 4C2ME 2R93F 5M5YE 3HOZE 2Y0SH 4A3FF 1TWCE 1Y1VF 5IP7F 4BBRE 4OIQE 1DZFA 2O5JE 4A3MF 2JA6F 1WCME 2PMZK 2NVYF 2VUMF 3HOUF 5IYBE 3I4NE 2O5IE 3HOYE 3GTPE 3HOWE 4A3BE 2BE5E 4Y7NE 5D4DE 3S1NF 3K7AF 4MEYE 5E17E 3HOVE 1YNNK 4C3IE 1TWFF 2R93E 2WB1H 3H0GF 2NVXF 3S1QF 4C3JF 5M5WF 1Y1VE 5IP7E 4A3ME 2JA6E 5M5YF 4QIWK 4A3JF 1I3QE 2NVYE 1TWAE 3HOUE 1YNJK 2WAQK 4BBRF 5IYDF 4BXXF 3S1NE 5D4EE 4BY7F 3K7AE 5M3FF 4XSXE 3S17F 3I4NF 5IPLE 3H0GE 3GTPF 4XSZE 2NVXE 3M4OF 5IP9F 4YFXE 3GTMF 1SMYE 2B63E 4A3IE 4GZYE 3PO3F 1I50F 3GTOF 5C44F 4A3JE 5C4XE 3H3VF 5IYDE 4BXXE 3HKZH 3PO2F 3EQLE 4BY7E 1I3QF 2NVQF 5M3FE 1Y1WE 3S17E 1TWAF 5FJ8F 2E2JE 4A3KF 3GTGF 4BBSF 3M4OE 5IP9E 3HOXF 3GTME 2A68E 4MQ9E 3FKIF 3PO3E 1I50E 3GTOE 4Q5SE 5TMFE 4XLPE 4A3EF 1R9TF 5FLME 5C44E 3H3VG 4A3CE 2B63F 4A3IF 4Y52F 2JA5F 3PO2E 5IYCF 5BYHE 5C4XF 4KMUE 2R7ZE 5D4CE 5FJ8E 4A3KE 1HQME 4JK1E 3S2HE 3GTGE 4BBSE 5C4JF 3HOXE 2JA8F 1Y1WF 3S1MF 2E2JF 3FKIE 2NVQE 5E18E 3S1RF 4A3EE 1R9TE 2E2HF 1K83F 4OIPE 4OIOE 4G7OE 1I6VE 1SFOF 3M3YF 4Y52E 2JA5E 3GTKF 5FLMF 5IYCE 4YFKE 4A3CF 2A69E 3DXJE 2E2IF 4LK1E 4XLNE 2JA8E 5C4JE 4AYBH 2R7ZF 3S1ME 1EIKA 2A6EE 3S2HF 2E2HE 3S1RE 4OIRE 1K83E 3HKZK 4A3GE 3S16F 1SFOE 3M3YE 4A93F 4LJZE 2KRXA 3GTKE 4G7ZE 3RZOE 4C3HF 3GTLF 3I4MF 2E2IE 2R92F 4BY1E 3S14E 4G7HE 3S15E 1IW7E 1ZYRE 3GTQF 2CW0E 4ZH4E 4A3DF 2YU9F 3GTJE 2NVTE 2PMZH 3S16E 5TMCE 2JA7F 4A3LF 1TWGF 4KN4E 4A93E 1QKLA 2A6HE 3CQZF 4C3HE 3GTLE 4A3GF 3I4ME 3S2DF 2Y0SI 4LK0E 2R92E 5C3EE 3RZOF 1TWHF 5M3MF 3RZDE 4A3DE 4OINE 1I6HF 2YU9E 4BY1F 3S14F 3S15F 4QIWH 5M5XF
chains in the Genus database with same CATH topology
2JA7E 4A3LE 1TWGE 2WAQH 4A3FE 3CQZE 3S2DE 2VUME 1TWHE 5M3ME 1I6HE 1TWFE 5M5XE 3GTQE 3S1QE 4X6AE 4C3JE 5M5WE 4C2ME 5M5YE 3HOZE 2Y0SH 1TWCE 4BBRE 1DZFA 1WCME 5IYBE 3I4NE 3HOYE 3GTPE 3HOWE 4A3BE 4Y7NE 3HOVE 2WB1H 4C3IE 2R93E 1Y1VE 5IP7E 4A3ME 2JA6E 1I3QE 2NVYE 1TWAE 3HOUE 3S1NE 3K7AE 3H0GE 2NVXE 2B63E 4A3IE 4A3JE 5C4XE 3H3VF 5IYDE 4BXXE 3HKZH 4BY7E 5M3FE 1Y1WE 3S17E 2E2JE 3M4OE 5IP9E 3GTME 3PO3E 1I50E 3GTOE 5FLME 5C44E 4A3CE 3PO2E 2R7ZE 5FJ8E 4A3KE 3S2HE 3GTGE 4BBSE 3HOXE 3FKIE 2NVQE 4A3EE 1R9TE 4Y52E 2JA5E 5IYCE 2JA8E 5C4JE 4AYBH 3S1ME 1EIKA 2E2HE 3S1RE 1K83E 4A3GE 1SFOE 3M3YE 3GTKE 3RZOE 2E2IE 4BY1E 3S14E 3S15E 3GTJE 2NVTE 2PMZH 3S16E 4A93E 4C3HE 3GTLE 3I4ME 2R92E 5C3EE 3RZDE 4A3DE 2YU9E 4QIWH
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JA7 E;  4A3L E;  1TWG E;  2WAQ H;  4A3F E;  3CQZ E;  3S2D E;  2VUM E;  1TWH E;  5M3M E;  1I6H E;  1TWF E;  5M5X E;  3GTQ E;  3S1Q E;  4X6A E;  4C3J E;  5M5W E;  4C2M E;  5M5Y E;  3HOZ E;  2Y0S H;  1TWC E;  4BBR E;  1DZF A;  1WCM E;  5IYB E;  3I4N E;  3HOY E;  3GTP E;  3HOW E;  4A3B E;  4Y7N E;  3HOV E;  2WB1 H;  4C3I E;  2R93 E;  1Y1V E;  5IP7 E;  4A3M E;  2JA6 E;  1I3Q E;  2NVY E;  1TWA E;  3HOU E;  3S1N E;  3K7A E;  3H0G E;  2NVX E;  2B63 E;  4A3I E;  4A3J E;  5C4X E;  3H3V F;  5IYD E;  4BXX E;  3HKZ H;  4BY7 E;  5M3F E;  1Y1W E;  3S17 E;  2E2J E;  3M4O E;  5IP9 E;  3GTM E;  3PO3 E;  1I50 E;  3GTO E;  5FLM E;  5C44 E;  4A3C E;  3PO2 E;  2R7Z E;  5FJ8 E;  4A3K E;  3S2H E;  3GTG E;  4BBS E;  3HOX E;  3FKI E;  2NVQ E;  4A3E E;  1R9T E;  4Y52 E;  2JA5 E;  5IYC E;  2JA8 E;  5C4J E;  4AYB H;  3S1M E;  1EIK A;  2E2H E;  3S1R E;  1K83 E;  4A3G E;  1SFO E;  3M3Y E;  3GTK E;  3RZO E;  2E2I E;  4BY1 E;  3S14 E;  3S15 E;  3GTJ E;  2NVT E;  2PMZ H;  3S16 E;  4A93 E;  4C3H E;  3GTL E;  3I4M E;  2R92 E;  5C3E E;  3RZD E;  4A3D E;  2YU9 E;  4QIW H; 
#chains in the Genus database with same CATH topology
 2JA7 E;  4A3L E;  1TWG E;  4Q4Z E;  2WAQ H;  3WOD E;  3GTJ F;  4A3F E;  4YFN E;  2WB1 I;  2PPB E;  2NVT F;  4C2M F;  3CQZ E;  3S2D E;  4AYB K;  3HOZ F;  1TWC F;  4LLG E;  2VUM E;  1TWH E;  4MEX E;  5M3M E;  1I6H E;  1WCM F;  5C3E F;  4X6A F;  5IYB F;  1TWF E;  3HOY F;  3HOW F;  3RZD F;  5M5X E;  4A3B F;  3GTQ E;  3S1Q E;  4X6A E;  4Y7N F;  4C3J E;  5M5W E;  4YG2 E;  3HOV F;  4C3I F;  4KN7 E;  4C2M E;  2R93 F;  5M5Y E;  3HOZ E;  2Y0S H;  4A3F F;  1TWC E;  1Y1V F;  5IP7 F;  4BBR E;  4OIQ E;  1DZF A;  2O5J E;  4A3M F;  2JA6 F;  1WCM E;  2PMZ K;  2NVY F;  2VUM F;  3HOU F;  5IYB E;  3I4N E;  2O5I E;  3HOY E;  3GTP E;  3HOW E;  4A3B E;  2BE5 E;  4Y7N E;  5D4D E;  3S1N F;  3K7A F;  4MEY E;  5E17 E;  3HOV E;  1YNN K;  4C3I E;  1TWF F;  2R93 E;  2WB1 H;  3H0G F;  2NVX F;  3S1Q F;  4C3J F;  5M5W F;  1Y1V E;  5IP7 E;  4A3M E;  2JA6 E;  5M5Y F;  4QIW K;  4A3J F;  1I3Q E;  2NVY E;  1TWA E;  3HOU E;  1YNJ K;  2WAQ K;  4BBR F;  5IYD F;  4BXX F;  3S1N E;  5D4E E;  4BY7 F;  3K7A E;  5M3F F;  4XSX E;  3S17 F;  3I4N F;  5IPL E;  3H0G E;  3GTP F;  4XSZ E;  2NVX E;  3M4O F;  5IP9 F;  4YFX E;  3GTM F;  1SMY E;  2B63 E;  4A3I E;  4GZY E;  3PO3 F;  1I50 F;  3GTO F;  5C44 F;  4A3J E;  5C4X E;  3H3V F;  5IYD E;  4BXX E;  3HKZ H;  3PO2 F;  3EQL E;  4BY7 E;  1I3Q F;  2NVQ F;  5M3F E;  1Y1W E;  3S17 E;  1TWA F;  5FJ8 F;  2E2J E;  4A3K F;  3GTG F;  4BBS F;  3M4O E;  5IP9 E;  3HOX F;  3GTM E;  2A68 E;  4MQ9 E;  3FKI F;  3PO3 E;  1I50 E;  3GTO E;  4Q5S E;  5TMF E;  4XLP E;  4A3E F;  1R9T F;  5FLM E;  5C44 E;  3H3V G;  4A3C E;  2B63 F;  4A3I F;  4Y52 F;  2JA5 F;  3PO2 E;  5IYC F;  5BYH E;  5C4X F;  4KMU E;  2R7Z E;  5D4C E;  5FJ8 E;  4A3K E;  1HQM E;  4JK1 E;  3S2H E;  3GTG E;  4BBS E;  5C4J F;  3HOX E;  2JA8 F;  1Y1W F;  3S1M F;  2E2J F;  3FKI E;  2NVQ E;  5E18 E;  3S1R F;  4A3E E;  1R9T E;  2E2H F;  1K83 F;  4OIP E;  4OIO E;  4G7O E;  1I6V E;  1SFO F;  3M3Y F;  4Y52 E;  2JA5 E;  3GTK F;  5FLM F;  5IYC E;  4YFK E;  4A3C F;  2A69 E;  3DXJ E;  2E2I F;  4LK1 E;  4XLN E;  2JA8 E;  5C4J E;  4AYB H;  2R7Z F;  3S1M E;  1EIK A;  2A6E E;  3S2H F;  2E2H E;  3S1R E;  4OIR E;  1K83 E;  3HKZ K;  4A3G E;  3S16 F;  1SFO E;  3M3Y E;  4A93 F;  4LJZ E;  2KRX A;  3GTK E;  4G7Z E;  3RZO E;  4C3H F;  3GTL F;  3I4M F;  2E2I E;  2R92 F;  4BY1 E;  3S14 E;  4G7H E;  3S15 E;  1IW7 E;  1ZYR E;  3GTQ F;  2CW0 E;  4ZH4 E;  4A3D F;  2YU9 F;  3GTJ E;  2NVT E;  2PMZ H;  3S16 E;  5TMC E;  2JA7 F;  4A3L F;  1TWG F;  4KN4 E;  4A93 E;  1QKL A;  2A6H E;  3CQZ F;  4C3H E;  3GTL E;  4A3G F;  3I4M E;  3S2D F;  2Y0S I;  4LK0 E;  2R92 E;  5C3E E;  3RZO F;  1TWH F;  5M3M F;  3RZD E;  4A3D E;  4OIN E;  1I6H F;  2YU9 E;  4BY1 F;  3S14 F;  3S15 F;  4QIW H;  5M5X F; 
#chains in the Genus database with same CATH homology
 2JA7 E;  4A3L E;  1TWG E;  2WAQ H;  4A3F E;  3CQZ E;  3S2D E;  2VUM E;  1TWH E;  5M3M E;  1I6H E;  1TWF E;  5M5X E;  3GTQ E;  3S1Q E;  4X6A E;  4C3J E;  5M5W E;  4C2M E;  5M5Y E;  3HOZ E;  2Y0S H;  1TWC E;  4BBR E;  1DZF A;  1WCM E;  5IYB E;  3I4N E;  3HOY E;  3GTP E;  3HOW E;  4A3B E;  4Y7N E;  3HOV E;  2WB1 H;  4C3I E;  2R93 E;  1Y1V E;  5IP7 E;  4A3M E;  2JA6 E;  1I3Q E;  2NVY E;  1TWA E;  3HOU E;  3S1N E;  3K7A E;  3H0G E;  2NVX E;  2B63 E;  4A3I E;  4A3J E;  5C4X E;  3H3V F;  5IYD E;  4BXX E;  3HKZ H;  4BY7 E;  5M3F E;  1Y1W E;  3S17 E;  2E2J E;  3M4O E;  5IP9 E;  3GTM E;  3PO3 E;  1I50 E;  3GTO E;  5FLM E;  5C44 E;  4A3C E;  3PO2 E;  2R7Z E;  5FJ8 E;  4A3K E;  3S2H E;  3GTG E;  4BBS E;  3HOX E;  3FKI E;  2NVQ E;  4A3E E;  1R9T E;  4Y52 E;  2JA5 E;  5IYC E;  2JA8 E;  5C4J E;  4AYB H;  3S1M E;  1EIK A;  2E2H E;  3S1R E;  1K83 E;  4A3G E;  1SFO E;  3M3Y E;  3GTK E;  3RZO E;  2E2I E;  4BY1 E;  3S14 E;  3S15 E;  3GTJ E;  2NVT E;  2PMZ H;  3S16 E;  4A93 E;  4C3H E;  3GTL E;  3I4M E;  2R92 E;  5C3E E;  3RZD E;  4A3D E;  2YU9 E;  4QIW H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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