1K83F

Crystal structure of yeast rna polymerase ii complexed with the inhibitor alpha amanitin
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
84
structure length
84
Chain Sequence
KAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of Transcription: Alpha-Amanitin-RNA Polymerase II Cocrystal at 2.8 A Resolution.
pubmed doi rcsb
molecule tags Transcription/toxin
molecule keywords DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT
total genus 23
structure length 84
sequence length 84
ec nomenclature
pdb deposition date 2001-10-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 1k83F00
3HKZK 1TWFF 4G7ZE 3M3YF 3DXJE 2R7ZF 1TWHF 2A69E 4A3IF 2E2JF 5D4CE 3EQLE 5IYBF 4ZH4E 4BBSF 4Q5SE 4BXXF 3S17F 4YFXE 3S1RF 1TWGF 3S2DF 1I6VE 2VUMF 3GTKF 5M5WF 4MEXE 2PMZK 5M5YF 4OIRE 3RZDF 5IP7F 1YNNK 1QKLA 1SMYE 4LJZE 2A68E 4A93F 5IYDF 4XLPE 5C44F 4OIQE 3S15F 5M3MF 1R9TF 1Y1WF 5C4JF 5FJ8F 4A3DF 4AYBK 4C2MF 4A3BF 3I4MF 2JA5F 2A6HE 2WB1I 1SFOF 3H3VG 3CQZF 4OIPE 4KMUE 3PO2F 4A3JF 3GTMF 3S1MF 1HQME 3HOXF 4MQ9E 3RZOF 1I50F 2JA7F 1Y1VF 3S14F 3FKIF 1IW7E 2R93F 1YNJK 4XSZE 5FLMF 5TMCE 5M5XF 2E2IF 1K83F 3WODE 2NVTF 2CW0E 4LK0E 5TMFE 4OINE 4A3KF 4KN7E 3GTGF 1I3QF 4BY1F 1ZYRE 2BE5E 4C3IF 3GTJF 4LLGE 2NVQF 4A3MF 3HOZF 5IYCF 2Y0SI 4XSXE 4C3JF 2PPBE 1I6HF 5IPLE 4YFKE 4Y7NF 2JA6F 4Y52F 5C4XF 4JK1E 5E17E 2B63F 1TWAF 5C3EF 4G7HE 3S16F 4LK1E 3HOVF 4MEYE 3S1QF 2A6EE 3HOUF 4OIOE 2YU9F 3GTPF 4A3FF 3M4OF 2O5JE 4C3HF 3H0GF 3GTLF 3S2HF 3HOYF 4X6AF 4BBRF 3I4NF 3S1NF 4YFNE 2O5IE 5IP9F 5BYHE 4A3EF 4A3GF 1TWCF 2WAQK 4YG2E 4Q4ZE 4A3LF 4GZYE 5M3FF 5D4DE 4G7OE 2JA8F 5E18E 3GTQF 4BY7F 4A3CF 5D4EE 1WCMF 2E2HF 2NVYF 3PO3F 3K7AF 2NVXF 3HOWF 4KN4E 2R92F 4XLNE 3GTOF
chains in the Genus database with same CATH superfamily
3S1RE 3HKZK 2JA8E 3GTQE 4A3CE 3S2DE 1TWFF 4G7ZE 2VUME 3DXJE 3GTKE 2NVYE 5M5WE 2R7ZF 1TWHF 3M3YF 3PO3E 2A69E 2Y0SH 2NVXE 4A3IF 2E2JF 5D4CE 3EQLE 5IYBF 4ZH4E 5IP7E 4BBSF 4Q5SE 1EIKA 4QIWH 4BXXF 4A93E 5IYDE 3S17F 5C44E 4YFXE 3GTPE 3S1RF 3S15E 1TWGF 1R9TE 1TWFE 1Y1WE 3S2DF 1I6VE 2KRXA 5FJ8E 2VUMF 3GTKF 4C2ME 1TWHE 5M5WF 3M3YE 4MEXE 4A3BE 2PMZK 5M5YF 4OIRE 5IYBE 3RZDF 5IP7F 2JA5E 1YNNK 1QKLA 1SMYE 4LJZE 2A68E 4A93F 5IYDF 4XLPE 5C44F 4OIQE 1TWGE 3S15F 5M3MF 1R9TF 4A3JE 3PO2E 1Y1WF 3S1ME 5C4JF 5FJ8F 3HOXE 4AYBK 3RZOE 4A3DF 4C2MF 2JA7E 1DZFA 5M5YE 4A3BF 2WAQH 3S14E 3RZDE 3FKIE 3I4MF 2R93E 3H3VF 2JA5F 5FLME 2A6HE 5M5XE 2WB1I 1SFOF 2E2IE 1K83E 3H3VG 3CQZF 5M3ME 4OIPE 4KMUE 3PO2F 4A3JF 3GTMF 5C4JE 4A3KE 1HQME 3HOXF 3S1MF 4A3DE 4MQ9E 3RZOF 1I50F 2JA7F 3GTGE 1I3QE 4C3IE 3GTJE 1Y1VF 4BY1E 3HOZE 3S14F 5IYCE 3FKIF 1IW7E 4C3JE 3I4ME 1YNJK 4XSZE 4Y7NE 1I6HE 2JA6E 5FLMF 2R93F 5TMCE 1SFOE 5M5XF 5C4XE 3HKZH 2E2IF 3CQZE 1K83F 1TWAE 3WODE 2B63E 5C3EE 2NVTF 2CW0E 4LK0E 5TMFE 4OINE 3GTME 3S16E 4A3KF 4KN7E 1I50E 3HOUE 3GTGF 1I3QF 1Y1VE 1ZYRE 2BE5E 4BY1F 4C3IF 4LLGE 4QIWK 3GTJF 4A3MF 5IYCF 2YU9E 4A3FE 2Y0SI 4XSXE 4C3JF 2PPBE 1I6HF 3M4OE 4YFKE 4Y7NF 2JA6F 5IPLE 4Y52F 4C3HE 5C4XF 4JK1E 3GTLE 5E17E 2B63F 1TWAF 3S2HE 4X6AE 4BBRE 5C3EF 4G7HE 3S1NE 3HOZF 2NVTE 5IP9E 4A3EE 3S16F 4LK1E 3HOVF 4MEYE 3S1QF 1TWCE 2PMZH 4A3LE 2A6EE 5M3FE 3HOUF 4OIOE 2NVQE 2YU9F 4A3ME 3GTPF 4A3FF 4BY7E 3M4OF 4Y52E 1WCME 2O5JE 4C3HF 3H0GF 2E2HE 3GTLF 3S2HF 3HOYF 4X6AF 4BBRF 3I4NF 3S1NF 3K7AE 4AYBH 3HOWE 4YFNE 2NVQF 5IP9F 2O5IE 3HOVE 5BYHE 4A3EF 2WB1H 3S1QE 4A3GF 2R92E 4YG2E 1TWCF 2WAQK 4Q4ZE 4A3LF 4GZYE 5M3FF 5D4DE 3GTOE 4G7OE 2JA8F 5E18E 3GTQF 4BY7F 4A3CF 5D4EE 1WCMF 3H0GE 2E2HF 2NVYF 2R7ZE 3HOYE 3PO3F 3I4NE 3K7AF 4A3IE 2E2JE 2NVXF 3HOWF 4KN4E 4BBSE 4A3GE 2R92F 4XLNE 4BXXE 3S17E 3GTOF
chains in the Genus database with same CATH topology
3HKZK 1TWFF 4G7ZE 3M3YF 3DXJE 2R7ZF 1TWHF 2A69E 4A3IF 2E2JF 5D4CE 3EQLE 5IYBF 4ZH4E 4BBSF 4Q5SE 4BXXF 3S17F 4YFXE 3S1RF 1TWGF 3S2DF 1I6VE 2KRXA 2VUMF 3GTKF 5M5WF 4MEXE 2PMZK 5M5YF 4OIRE 3RZDF 5IP7F 1YNNK 1QKLA 1SMYE 4LJZE 2A68E 4A93F 5IYDF 4XLPE 5C44F 4OIQE 3S15F 5M3MF 1R9TF 1Y1WF 5C4JF 5FJ8F 4A3DF 4AYBK 4C2MF 4A3BF 3I4MF 2JA5F 2A6HE 2WB1I 1SFOF 3H3VG 3CQZF 4OIPE 4KMUE 3PO2F 4A3JF 3GTMF 3S1MF 1HQME 3HOXF 4MQ9E 3RZOF 1I50F 2JA7F 1Y1VF 3S14F 3FKIF 1IW7E 2R93F 1YNJK 4XSZE 5FLMF 5TMCE 5M5XF 2E2IF 1K83F 3WODE 2NVTF 2CW0E 4LK0E 5TMFE 4OINE 4A3KF 4KN7E 3GTGF 1I3QF 4BY1F 1ZYRE 2BE5E 4C3IF 3GTJF 4LLGE 4QIWK 4A3MF 2NVQF 5IYCF 2Y0SI 4XSXE 4C3JF 2PPBE 1I6HF 5IPLE 4YFKE 4Y7NF 2JA6F 4Y52F 5C4XF 4JK1E 5E17E 2B63F 1TWAF 5C3EF 4G7HE 3HOZF 3S16F 4LK1E 3HOVF 4MEYE 3S1QF 2A6EE 3HOUF 4OIOE 2YU9F 3GTPF 4A3FF 3M4OF 2O5JE 4C3HF 3H0GF 3GTLF 3S2HF 3HOYF 4X6AF 4BBRF 3I4NF 3S1NF 4YFNE 2O5IE 5IP9F 5BYHE 4A3EF 4A3GF 1TWCF 2WAQK 4YG2E 4Q4ZE 4A3LF 4GZYE 5M3FF 5D4DE 4G7OE 2JA8F 5E18E 3GTQF 4BY7F 4A3CF 5D4EE 1WCMF 2E2HF 2NVYF 3PO3F 3K7AF 2NVXF 3HOWF 4KN4E 2R92F 4XLNE 3GTOF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HKZ K;  1TWF F;  4G7Z E;  3M3Y F;  3DXJ E;  2R7Z F;  1TWH F;  2A69 E;  4A3I F;  2E2J F;  5D4C E;  3EQL E;  5IYB F;  4ZH4 E;  4BBS F;  4Q5S E;  4BXX F;  3S17 F;  4YFX E;  3S1R F;  1TWG F;  3S2D F;  1I6V E;  2VUM F;  3GTK F;  5M5W F;  4MEX E;  2PMZ K;  5M5Y F;  4OIR E;  3RZD F;  5IP7 F;  1YNN K;  1QKL A;  1SMY E;  4LJZ E;  2A68 E;  4A93 F;  5IYD F;  4XLP E;  5C44 F;  4OIQ E;  3S15 F;  5M3M F;  1R9T F;  1Y1W F;  5C4J F;  5FJ8 F;  4A3D F;  4AYB K;  4C2M F;  4A3B F;  3I4M F;  2JA5 F;  2A6H E;  2WB1 I;  1SFO F;  3H3V G;  3CQZ F;  4OIP E;  4KMU E;  3PO2 F;  4A3J F;  3GTM F;  3S1M F;  1HQM E;  3HOX F;  4MQ9 E;  3RZO F;  1I50 F;  2JA7 F;  1Y1V F;  3S14 F;  3FKI F;  1IW7 E;  2R93 F;  1YNJ K;  4XSZ E;  5FLM F;  5TMC E;  5M5X F;  2E2I F;  1K83 F;  3WOD E;  2NVT F;  2CW0 E;  4LK0 E;  5TMF E;  4OIN E;  4A3K F;  4KN7 E;  3GTG F;  1I3Q F;  4BY1 F;  1ZYR E;  2BE5 E;  4C3I F;  3GTJ F;  4LLG E;  2NVQ F;  4A3M F;  3HOZ F;  5IYC F;  2Y0S I;  4XSX E;  4C3J F;  2PPB E;  1I6H F;  5IPL E;  4YFK E;  4Y7N F;  2JA6 F;  4Y52 F;  5C4X F;  4JK1 E;  5E17 E;  2B63 F;  1TWA F;  5C3E F;  4G7H E;  3S16 F;  4LK1 E;  3HOV F;  4MEY E;  3S1Q F;  2A6E E;  3HOU F;  4OIO E;  2YU9 F;  3GTP F;  4A3F F;  3M4O F;  2O5J E;  4C3H F;  3H0G F;  3GTL F;  3S2H F;  3HOY F;  4X6A F;  4BBR F;  3I4N F;  3S1N F;  4YFN E;  2O5I E;  5IP9 F;  5BYH E;  4A3E F;  4A3G F;  1TWC F;  2WAQ K;  4YG2 E;  4Q4Z E;  4A3L F;  4GZY E;  5M3F F;  5D4D E;  4G7O E;  2JA8 F;  5E18 E;  3GTQ F;  4BY7 F;  4A3C F;  5D4E E;  1WCM F;  2E2H F;  2NVY F;  3PO3 F;  3K7A F;  2NVX F;  3HOW F;  4KN4 E;  2R92 F;  4XLN E;  3GTO F; 
#chains in the Genus database with same CATH topology
 3S1R E;  3HKZ K;  2JA8 E;  3GTQ E;  4A3C E;  3S2D E;  1TWF F;  4G7Z E;  2VUM E;  3DXJ E;  3GTK E;  2NVY E;  5M5W E;  2R7Z F;  1TWH F;  3M3Y F;  3PO3 E;  2A69 E;  2Y0S H;  2NVX E;  4A3I F;  2E2J F;  5D4C E;  3EQL E;  5IYB F;  4ZH4 E;  5IP7 E;  4BBS F;  4Q5S E;  1EIK A;  4QIW H;  4BXX F;  4A93 E;  5IYD E;  3S17 F;  5C44 E;  4YFX E;  3GTP E;  3S1R F;  3S15 E;  1TWG F;  1R9T E;  1TWF E;  1Y1W E;  3S2D F;  1I6V E;  2KRX A;  5FJ8 E;  2VUM F;  3GTK F;  4C2M E;  1TWH E;  5M5W F;  3M3Y E;  4MEX E;  4A3B E;  2PMZ K;  5M5Y F;  4OIR E;  5IYB E;  3RZD F;  5IP7 F;  2JA5 E;  1YNN K;  1QKL A;  1SMY E;  4LJZ E;  2A68 E;  4A93 F;  5IYD F;  4XLP E;  5C44 F;  4OIQ E;  1TWG E;  3S15 F;  5M3M F;  1R9T F;  4A3J E;  3PO2 E;  1Y1W F;  3S1M E;  5C4J F;  5FJ8 F;  3HOX E;  4AYB K;  3RZO E;  4A3D F;  4C2M F;  2JA7 E;  1DZF A;  5M5Y E;  4A3B F;  2WAQ H;  3S14 E;  3RZD E;  3FKI E;  3I4M F;  2R93 E;  3H3V F;  2JA5 F;  5FLM E;  2A6H E;  5M5X E;  2WB1 I;  1SFO F;  2E2I E;  1K83 E;  3H3V G;  3CQZ F;  5M3M E;  4OIP E;  4KMU E;  3PO2 F;  4A3J F;  3GTM F;  5C4J E;  4A3K E;  1HQM E;  3HOX F;  3S1M F;  4A3D E;  4MQ9 E;  3RZO F;  1I50 F;  2JA7 F;  3GTG E;  1I3Q E;  4C3I E;  3GTJ E;  1Y1V F;  4BY1 E;  3HOZ E;  3S14 F;  5IYC E;  3FKI F;  1IW7 E;  4C3J E;  3I4M E;  1YNJ K;  4XSZ E;  4Y7N E;  1I6H E;  2JA6 E;  5FLM F;  2R93 F;  5TMC E;  1SFO E;  5M5X F;  5C4X E;  3HKZ H;  2E2I F;  3CQZ E;  1K83 F;  1TWA E;  3WOD E;  2B63 E;  5C3E E;  2NVT F;  2CW0 E;  4LK0 E;  5TMF E;  4OIN E;  3GTM E;  3S16 E;  4A3K F;  4KN7 E;  1I50 E;  3HOU E;  3GTG F;  1I3Q F;  1Y1V E;  1ZYR E;  2BE5 E;  4BY1 F;  4C3I F;  4LLG E;  4QIW K;  3GTJ F;  4A3M F;  5IYC F;  2YU9 E;  4A3F E;  2Y0S I;  4XSX E;  4C3J F;  2PPB E;  1I6H F;  3M4O E;  4YFK E;  4Y7N F;  2JA6 F;  5IPL E;  4Y52 F;  4C3H E;  5C4X F;  4JK1 E;  3GTL E;  5E17 E;  2B63 F;  1TWA F;  3S2H E;  4X6A E;  4BBR E;  5C3E F;  4G7H E;  3S1N E;  3HOZ F;  2NVT E;  5IP9 E;  4A3E E;  3S16 F;  4LK1 E;  3HOV F;  4MEY E;  3S1Q F;  1TWC E;  2PMZ H;  4A3L E;  2A6E E;  5M3F E;  3HOU F;  4OIO E;  2NVQ E;  2YU9 F;  4A3M E;  3GTP F;  4A3F F;  4BY7 E;  3M4O F;  4Y52 E;  1WCM E;  2O5J E;  4C3H F;  3H0G F;  2E2H E;  3GTL F;  3S2H F;  3HOY F;  4X6A F;  4BBR F;  3I4N F;  3S1N F;  3K7A E;  4AYB H;  3HOW E;  4YFN E;  2NVQ F;  5IP9 F;  2O5I E;  3HOV E;  5BYH E;  4A3E F;  2WB1 H;  3S1Q E;  4A3G F;  2R92 E;  4YG2 E;  1TWC F;  2WAQ K;  4Q4Z E;  4A3L F;  4GZY E;  5M3F F;  5D4D E;  3GTO E;  4G7O E;  2JA8 F;  5E18 E;  3GTQ F;  4BY7 F;  4A3C F;  5D4E E;  1WCM F;  3H0G E;  2E2H F;  2NVY F;  2R7Z E;  3HOY E;  3PO3 F;  3I4N E;  3K7A F;  4A3I E;  2E2J E;  2NVX F;  3HOW F;  4KN4 E;  4BBS E;  4A3G E;  2R92 F;  4XLN E;  4BXX E;  3S17 E;  3GTO F; 
#chains in the Genus database with same CATH homology
 3HKZ K;  1TWF F;  4G7Z E;  3M3Y F;  3DXJ E;  2R7Z F;  1TWH F;  2A69 E;  4A3I F;  2E2J F;  5D4C E;  3EQL E;  5IYB F;  4ZH4 E;  4BBS F;  4Q5S E;  4BXX F;  3S17 F;  4YFX E;  3S1R F;  1TWG F;  3S2D F;  1I6V E;  2KRX A;  2VUM F;  3GTK F;  5M5W F;  4MEX E;  2PMZ K;  5M5Y F;  4OIR E;  3RZD F;  5IP7 F;  1YNN K;  1QKL A;  1SMY E;  4LJZ E;  2A68 E;  4A93 F;  5IYD F;  4XLP E;  5C44 F;  4OIQ E;  3S15 F;  5M3M F;  1R9T F;  1Y1W F;  5C4J F;  5FJ8 F;  4A3D F;  4AYB K;  4C2M F;  4A3B F;  3I4M F;  2JA5 F;  2A6H E;  2WB1 I;  1SFO F;  3H3V G;  3CQZ F;  4OIP E;  4KMU E;  3PO2 F;  4A3J F;  3GTM F;  3S1M F;  1HQM E;  3HOX F;  4MQ9 E;  3RZO F;  1I50 F;  2JA7 F;  1Y1V F;  3S14 F;  3FKI F;  1IW7 E;  2R93 F;  1YNJ K;  4XSZ E;  5FLM F;  5TMC E;  5M5X F;  2E2I F;  1K83 F;  3WOD E;  2NVT F;  2CW0 E;  4LK0 E;  5TMF E;  4OIN E;  4A3K F;  4KN7 E;  3GTG F;  1I3Q F;  4BY1 F;  1ZYR E;  2BE5 E;  4C3I F;  3GTJ F;  4LLG E;  4QIW K;  4A3M F;  2NVQ F;  5IYC F;  2Y0S I;  4XSX E;  4C3J F;  2PPB E;  1I6H F;  5IPL E;  4YFK E;  4Y7N F;  2JA6 F;  4Y52 F;  5C4X F;  4JK1 E;  5E17 E;  2B63 F;  1TWA F;  5C3E F;  4G7H E;  3HOZ F;  3S16 F;  4LK1 E;  3HOV F;  4MEY E;  3S1Q F;  2A6E E;  3HOU F;  4OIO E;  2YU9 F;  3GTP F;  4A3F F;  3M4O F;  2O5J E;  4C3H F;  3H0G F;  3GTL F;  3S2H F;  3HOY F;  4X6A F;  4BBR F;  3I4N F;  3S1N F;  4YFN E;  2O5I E;  5IP9 F;  5BYH E;  4A3E F;  4A3G F;  1TWC F;  2WAQ K;  4YG2 E;  4Q4Z E;  4A3L F;  4GZY E;  5M3F F;  5D4D E;  4G7O E;  2JA8 F;  5E18 E;  3GTQ F;  4BY7 F;  4A3C F;  5D4E E;  1WCM F;  2E2H F;  2NVY F;  3PO3 F;  3K7A F;  2NVX F;  3HOW F;  4KN4 E;  2R92 F;  4XLN E;  3GTO F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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