1NQEA

Outer membrane cobalamin transporter (btub) from e. coli
Total Genus 151
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
151
sequence length
589
structure length
549
Chain Sequence
DTLVVTANRFEQPRSTVLAPTTVVTRQDIDRWQSTSVNDVLRRLPGVDITQNGGSGQLSSIFIRGTNASHVLVLIDGVRLNLAGVSGSADLSQFPIALVQRVEYIRGPRSAVYGSDAIGGVVNIITTRDEPGTEISAGWGSNSYQNYDVSTQQQLGDKTRVTLLGDYAHTHGGFLSKTLYGALEHNFTDAWSGFVRGYGYDNRTNDTRKLYSQSWDAGLRYNGELIKSQLITSYSHSKDYNYATLDEMKQYTVQWANNVIVGHGSIGAGVDWQKQTTTPGTGYVEDGYDQRNTGIYLTGLQQVGDFTFEGAARSDDNSQFGRHGTWQTSAGWEFIEGYRFIASYGTSYKAPNLGQLYGFYGNPNLDPEKSKQWEGAFEGLTAGVNWRISGYRNDVSDLIDYDDHTLKYYNEGKARIKGVEATANFDTGPLTHTVSYDYVDARNAITDTPLLRRAKQQVKYQLDWQLYDFDWGITYQYLGTRYDKDYSSYPYQTVKMGGVSLWDLAVAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Substrate-induced transmembrane signaling in the cobalamin transporter BtuB
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli
molecule keywords Vitamin B12 receptor
total genus 151
structure length 549
sequence length 589
ec nomenclature
pdb deposition date 2003-01-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00593 TonB_dep_Rec TonB dependent receptor
A PF07715 Plug TonB-dependent Receptor Plug Domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.170.20 Mainly Beta Beta Barrel Maltoporin; Chain A TonB-dependent receptor, beta-barrel domain 1nqeA02
2.170.130.10 Mainly Beta Beta Complex Ferric Hydroxamate Uptake Protein; Chain A, domain 1 TonB-dependent receptor, plug domain 1nqeA01
2HDFA 2HDIA 3DDRA 3RGNA 3V89A 1BY3A 3RGMA 2W6TA 2W78A 2GUFA 1KMPA 4AIPA 1QFFA 1QJQA 1FCPA 1FI1A 1NQEA 4B7OA 1NQFA 2FCPA 2GRXA 2GSKA 4RDRA 1PO3A 2W76A 1KMOA 1PNZA 1BY5A 4CU4A 1FEPA 2W77A 2IAHA 2W16A 2YSUA 4RDTA 3CSLA 2W75A 4AIQA 1PO0A 4EPAA 2O5PA 1NQGA 3QLBA 2W6UA 1UJWA 3M8DA 1XKHA 3FHHA 5FOKA 3EFMA 3M8BA 1XKWA 1QKCA 3V8XA 1NQHA 1QFGA 3CSNA
chains in the Genus database with same CATH superfamily
2HDFA 2HDIA 3DDRA 3RGNA 3V89A 1BY3A 3RGMA 2W6TA 1MPQA 2W78A 2GUFA 1MALA 1KMPA 4AIPA 1OH2Q 1QFFA 1QJQA 1FCPA 1MPOA 1FI1A 1NQEA 4B7OA 1NQFA 2FCPA 2GRXA 1MPRA 2GSKA 1UJWA 4RDRA 1PO3A 2W76A 1MPMA 1KMOA 2MPRA 1PNZA 1BY5A 4CU4A 1FEPA 2W77A 1OH2P 2IAHA 2YSUA 2W16A 4RDTA 3CSLA 2W75A 4AIQA 1PO0A 4EPAA 2O5PA 1AF6A 3QLBA 2W6UA 1A0SP 1MPNA 3M8DA 1NQGA 5FOKA 1A0TP 3EFMA 1XKHA 3FHHA 1JBIA 3M8BA 1XKWA 1QKCA 3V8XA 1NQHA 1QFGA 3CSNA
chains in the Genus database with same CATH topology
2HDFA 2HDIA 3DDRA 3RGNA 3V89A 1BY3A 3RGMA 2W6TA 2W78A 2GUFA 1KMPA 4AIPA 1QFFA 1QJQA 1FCPA 1FI1A 1NQEA 4B7OA 1NQFA 2FCPA 2GRXA 2GSKA 4RDRA 1PO3A 2W76A 1KMOA 1PNZA 1BY5A 4CU4A 1FEPA 2W77A 2IAHA 2W16A 2YSUA 4RDTA 3CSLA 2W75A 4AIQA 1PO0A 4EPAA 2O5PA 1NQGA 3QLBA 2W6UA 1UJWA 3M8DA 1XKHA 3FHHA 5FOKA 3EFMA 3M8BA 1XKWA 1QKCA 3V8XA 1NQHA 1QFGA 3CSNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HDF A;  2HDI A;  3DDR A;  3RGN A;  3V89 A;  1BY3 A;  3RGM A;  2W6T A;  2W78 A;  2GUF A;  1KMP A;  4AIP A;  1QFF A;  1QJQ A;  1FCP A;  1FI1 A;  1NQE A;  4B7O A;  1NQF A;  2FCP A;  2GRX A;  2GSK A;  4RDR A;  1PO3 A;  2W76 A;  1KMO A;  1PNZ A;  1BY5 A;  4CU4 A;  1FEP A;  2W77 A;  2IAH A;  2W16 A;  2YSU A;  4RDT A;  3CSL A;  2W75 A;  4AIQ A;  1PO0 A;  4EPA A;  2O5P A;  1NQG A;  3QLB A;  2W6U A;  1UJW A;  3M8D A;  1XKH A;  3FHH A;  5FOK A;  3EFM A;  3M8B A;  1XKW A;  1QKC A;  3V8X A;  1NQH A;  1QFG A;  3CSN A; 
#chains in the Genus database with same CATH topology
 2HDF A;  2HDI A;  3DDR A;  3RGN A;  3V89 A;  1BY3 A;  3RGM A;  2W6T A;  1MPQ A;  2W78 A;  2GUF A;  1MAL A;  1KMP A;  4AIP A;  1OH2 Q;  1QFF A;  1QJQ A;  1FCP A;  1MPO A;  1FI1 A;  1NQE A;  4B7O A;  1NQF A;  2FCP A;  2GRX A;  1MPR A;  2GSK A;  1UJW A;  4RDR A;  1PO3 A;  2W76 A;  1MPM A;  1KMO A;  2MPR A;  1PNZ A;  1BY5 A;  4CU4 A;  1FEP A;  2W77 A;  1OH2 P;  2IAH A;  2YSU A;  2W16 A;  4RDT A;  3CSL A;  2W75 A;  4AIQ A;  1PO0 A;  4EPA A;  2O5P A;  1AF6 A;  3QLB A;  2W6U A;  1A0S P;  1MPN A;  3M8D A;  1NQG A;  5FOK A;  1A0T P;  3EFM A;  1XKH A;  3FHH A;  1JBI A;  3M8B A;  1XKW A;  1QKC A;  3V8X A;  1NQH A;  1QFG A;  3CSN A; 
#chains in the Genus database with same CATH homology
 2HDF A;  2HDI A;  3DDR A;  3RGN A;  3V89 A;  1BY3 A;  3RGM A;  2W6T A;  2W78 A;  2GUF A;  1KMP A;  4AIP A;  1QFF A;  1QJQ A;  1FCP A;  1FI1 A;  1NQE A;  4B7O A;  1NQF A;  2FCP A;  2GRX A;  2GSK A;  4RDR A;  1PO3 A;  2W76 A;  1KMO A;  1PNZ A;  1BY5 A;  4CU4 A;  1FEP A;  2W77 A;  2IAH A;  2W16 A;  2YSU A;  4RDT A;  3CSL A;  2W75 A;  4AIQ A;  1PO0 A;  4EPA A;  2O5P A;  1NQG A;  3QLB A;  2W6U A;  1UJW A;  3M8D A;  1XKH A;  3FHH A;  5FOK A;  3EFM A;  3M8B A;  1XKW A;  1QKC A;  3V8X A;  1NQH A;  1QFG A;  3CSN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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