1PEXA

Collagenase-3 (mmp-13) c-terminal hemopexin-like domain
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
192
structure length
192
Chain Sequence
TPDKCDPSLSLDAITSLRGETMIFKDRFFWRLHPQQVDAELFLTKSFWPELPNRIDAAYEHPSHDLIFIFRGRKFWALNGYDILEGYPKKISELGLPKEVKKISAAVHFEDTGKTLLFSGNQVWRYDDTNHIMDKDYPRLIEEDFPGIGDKVDAVYEKNGYIYFFNGPIQFEYSIWSNRIVRVMPANSILWC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The helping hand of collagenase-3 (MMP-13): 2.7 A crystal structure of its C-terminal haemopexin-like domain.
pubmed doi rcsb
molecule tags Metalloprotease
source organism Homo sapiens
molecule keywords COLLAGENASE-3
total genus 32
structure length 192
sequence length 192
ec nomenclature ec 3.4.24.-:
pdb deposition date 1996-05-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00045 Hemopexin Hemopexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.110.10.10 Mainly Beta 4 Propeller Hemopexin Hemopexin-like domain 1pexA00
1SU3A 4LL2A 1RTGA 1CK7A 3C7XA 1QJSA 4YEHA 1GENA 4HSDA 3S18A 3V6NA 4FVLA 1PEXA 2MQSA 3LP9A 3OYOA 1QHUA 3BA0A 1HXNA 4OEIA 2JXYA 1FBLA 1ITVA 2CLTA 1GXDA 4RT6B 4AUOA 4FU4A 4G0DA
chains in the Genus database with same CATH superfamily
1SU3A 4LL2A 1RTGA 1CK7A 3C7XA 1QJSA 4YEHA 1GENA 4HSDA 3S18A 3V6NA 4FVLA 1PEXA 2MQSA 3LP9A 3OYOA 1QHUA 3BA0A 1HXNA 4OEIA 2JXYA 1FBLA 1ITVA 2CLTA 1GXDA 4RT6B 4AUOA 4FU4A 4G0DA
chains in the Genus database with same CATH topology
1SU3A 4LL2A 1RTGA 1CK7A 3C7XA 1QJSA 4YEHA 1GENA 4HSDA 3S18A 3V6NA 4FVLA 1PEXA 2MQSA 3LP9A 3OYOA 1QHUA 3BA0A 1HXNA 4OEIA 2JXYA 1FBLA 1ITVA 2CLTA 1GXDA 4RT6B 4AUOA 4FU4A 4G0DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SU3 A;  4LL2 A;  1RTG A;  1CK7 A;  3C7X A;  1QJS A;  4YEH A;  1GEN A;  4HSD A;  3S18 A;  3V6N A;  4FVL A;  1PEX A;  2MQS A;  3LP9 A;  3OYO A;  1QHU A;  3BA0 A;  1HXN A;  4OEI A;  2JXY A;  1FBL A;  1ITV A;  2CLT A;  1GXD A;  4RT6 B;  4AUO A;  4FU4 A;  4G0D A; 
#chains in the Genus database with same CATH topology
 1SU3 A;  4LL2 A;  1RTG A;  1CK7 A;  3C7X A;  1QJS A;  4YEH A;  1GEN A;  4HSD A;  3S18 A;  3V6N A;  4FVL A;  1PEX A;  2MQS A;  3LP9 A;  3OYO A;  1QHU A;  3BA0 A;  1HXN A;  4OEI A;  2JXY A;  1FBL A;  1ITV A;  2CLT A;  1GXD A;  4RT6 B;  4AUO A;  4FU4 A;  4G0D A; 
#chains in the Genus database with same CATH homology
 1SU3 A;  4LL2 A;  1RTG A;  1CK7 A;  3C7X A;  1QJS A;  4YEH A;  1GEN A;  4HSD A;  3S18 A;  3V6N A;  4FVL A;  1PEX A;  2MQS A;  3LP9 A;  3OYO A;  1QHU A;  3BA0 A;  1HXN A;  4OEI A;  2JXY A;  1FBL A;  1ITV A;  2CLT A;  1GXD A;  4RT6 B;  4AUO A;  4FU4 A;  4G0D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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