3BA0A

Crystal structure of full-length human mmp-12
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
365
structure length
365
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYGDPKENQRLPNPDNSEPALCDPNLSFDAVTTVGNKIFFFKDRFFWLKVSERPKTSVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDKYWLISNLRPEPNYPKSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKLITKNFQGIGPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRITKTLKSNSWFGC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Macrophage metalloelastase
publication title Evidence of reciprocal reorientation of the catalytic and hemopexin-like domains of full-length MMP-12.
pubmed doi rcsb
source organism Homo sapiens
total genus 56
structure length 365
sequence length 365
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2007-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00045 Hemopexin Hemopexin
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.110.10.10 Mainly Beta 4 Propeller Hemopexin Hemopexin-like domain 3ba0A02
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3ba0A01
1CQRA 1D8FA 1HY7A 2FV5A 3U1RA 2CKIA 3B92A 5BOYA 4XBHA 1USNA 3LMCA 830CA 1HFSA 4H1QA 1ROSA 4CTHA 1IADA 1XFWA 2X7MA 2JT5A 3E8RA 4DPEA 2XS3A 1XUCA 1MNCA 3B8ZA 2OVZA 3LQBA 2QPJA 4H2EA 1YOUA 1DTHA 1QIAA 2AIGP 1KAPP 3HY9A 3KHIA 2DDYA 1OS9A 1IABA 4GWMA 3DPFA 4PKTA 3MA2A 4A7BA 4JA1A 1ITVA 2K2GA 2N8RA 4I03A 5D1SA 1OMJA 4L6TA 1BKCE 1UMTA 1JK3A 5D3CA 1SLMA 1A86A 456CA 3ZVSA 3G42A 3LJZA 4GR0A 3TT4A 4HSDA 4ON1A 1FBLA 2L0RA 1SU3A 1BSWA 5B5PA 5D7WA 1KUFA 4YEHA 3I7GA 1HV5A 3L0TA 2JIHA 3GBOA 2WO9A 4PKWA 4H30A 1MMRA 3KEJA 1YCMA 3EWJA 1GKDA 3KECA 1PEXA 3HYGA 3EDGA 3S18A 3RTSA 1D5JA 3LEAA 3UVCA 2J0TA 3P24A 1BZSA 1EUBA 1SLNA 2X3AA 3HBVP 2HU6A 2MLSA 2USNA 3EHXA 3LP9A 3Q2HA 3I7IA 1JANA 3OYOA 1XFYA 1H71P 2OVXA 1GXDA 1GE6A 3KWVC 4H76A 1JKYA 1GO8P 3K7NA 4WK7A 3LGPA 1JIZA 1GE7A 3F18A 1K7IA 5B5OA 4H3XA 3EDIA 3DL1A 4FXYP 2OW0A 4ILWD 4PKUA 1OS2A 2DDFA 3DPEA 2I47A 3EDZA 4GR8A 2OXZA 4XCTA 1Q3AA 1IAGA 1Y93A 3F19A 5I2ZA 4XM8A 2W14A 1GO7P 1XFVA 3TS4A 3LE9A 2AYKA 3K7LA 2YIGA 1AKLA 2X3BA 1HTDA 3F16A 1RTGA 4WKIA 1JAQA 2J83A 2Z2DA 1BUVM 1R1JA 1UTZA 2D1OA 2Y6DA 1ZTQA 3O2XA 3EHYA 3USNA 1B3DA 2MQSA 1CIZA 4GF1A 1QUAA 4G9LA 1XURA 2OW9A 2WOAA 5JMYA 1G4KA 1IAEA 2E3XA 1C7KA 3C7XA 1KBCA 1BKCA 4I35A 2DW2A 3SHIA 1O0TA 1PWPA 1L6JA 2K9CA 5BPAA 1IAAA 2W15A 3LJGA 5L7FA 1Y0VA 1ATLA 1CGEA 2MZHA 3B2ZA 3LK8A 1PWUA 966CA 1HOVA 4JIJA 5CUHA 2JSDA 1RM8A 1UTTA 1B8YA 2JNPA 3KRYA 4L63A 1FM1A 4FXQA 3HY7A 3F15A 1JAPA 1CK7A 4XM6A 4PKSA 2DW0A 1GE5A 3ZUKA 1CGLA 4RT6B 2OZRA 2OW1A 1KUHA 4JQGA 2OXWA 2D1NA 4L19A 1ZXVA 3AYUA 4LL2A 3LKAA 3DNGA 1ASTA 1O0QA 1XFUA 1DMTA 3L0VA 1KUKA 1OM6A 3LIKA 2KRJA 1QIBA 2POJA 3LUMA 1QJJA 3NX7A 3LJTA 2W0DA 5CZMA 1XFXA 4Q1LA 1KUGA 3O64A 1K7GA 2TCLA 1R54A 1S4BP 1GENA 3V96B 1WNIA 2ERQA 4HMAA 1MMBA 1R1HA 2MZIA 4J4MA 1R1IA 1D8MA 2ERPA 1ND1A 1G12A 4A3WA 5BOTA 1BKCI 3BA0A 1AYKA 4IUWA 1SMPA 2SRTA 1Y8JA 1PWWA 2V4BA 2PJTA 1EB6A 2W12A 4DF9A 2FV9A 2MZEA 3LILA 3VI1A 1HFCA 4EFSA 4GUYA 3G5CA 1BIWA 1XUDA 3WV1A 5I43A 1MMPA 1ZP5A 3HDAP 3F1AA 3Q2GA 3V6NA 1JIWP 3OHOA 4IJOA 1PWQA 2Y6CA 1JH1A 2X3CA 1G9KA 3N2UA 3LUNA 1C8TA 1D7XA 1OM8A 2YB9A 3KMCA 1YP1A 1QICA 5LABA 5D2BA 3ZXHA 4AUOA 4IN9A 1GKCA 4R3VA 1BQQM 1FLSA 3LQ0A 4AXQA 1A85A 2EROA 2OY2A 4H49A 5I12A 1ZS0A 1I73A 1C3IA 1AF0A 4WF6A 1SATA 3WV3A 4ZR5A 1OM7A 1UMSA 2JXYA 3TSKA 2OI0A 3HBUP 2A8HA 1HXNA 3P1VA 1EAKA 1CAQA 1OO9A 5L79A 1BM6A 3F17A 1G49A 3DSLA 5I0LA 3RTTA 1JJ9A 4GR3A 1CXVA 4WKEA 4G0DA 1JAOA 2OW2A 1UEAA 4JP4A 5I4OA 1I76A 3VTGA 2MLRA 1RMZA 3EDHA 1XFZA 1IACA 2CLTA 4DD8A 2JT6A 4PKRA 1QJSA 3HDBA 2W13A 4AYKA 3HB2P 5D1TA 2RJPA 3TVCA 2DW1A 4HX3A 1J7NA 4PKVA 1ZVXA 3WV2A 4WZVA 3KMEA 4OEIA 4AIGA 3N2VA 1QJIA 4GQLA 2OY4A 1BQOA 5D1UA 3ELMA 4PKQA 1YQYA 3OHLA 1MMQA 3DWBA 1R55A 1ZXCA 1Z3JA 4GWNA 4FVLA 2OXUA 5H8XA 3CKIA 4FU4A 1CGFA 3KEKA 3LIRA 4H84A 2WO8A 5I3MA 1KUIA 2E2DA 3AIGA 1I1IP 3AYKA 2O36A 1QHUA 2O3EA 4DV8A 1BUDA 1G05A 4JPAA 1PWVA 4XM7A 4H82A 4QKZA 2XS4A 2RJQA 1K7QA 1SRPA 5CXAA
chains in the Genus database with same CATH superfamily
1CQRA 1D8FA 1HY7A 2FV5A 3U1RA 2CKIA 3B92A 5BOYA 4XBHA 1USNA 2YUFA 3LMCA 830CA 1HFSA 4H1QA 1ROSA 4CTHA 1IADA 1XFWA 2X7MA 2JT5A 3E8RA 4DPEA 2XS3A 1XUCA 1MNCA 3B8ZA 2OVZA 3LQBA 2QPJA 4H2EA 1YOUA 1DTHA 1QIAA 2AIGP 1KAPP 3HY9A 3KHIA 2DDYA 1OS9A 1IABA 4GWMA 3DPFA 4PKTA 3MA2A 4A7BA 4JA1A 1ITVA 2K2GA 2N8RA 4I03A 5D1SA 1OMJA 4L6TA 1BKCE 1UMTA 1JK3A 5D3CA 1SLMA 1A86A 456CA 3ZVSA 3G42A 3LJZA 4GR0A 3TT4A 4HSDA 4ON1A 1FBLA 2L0RA 1SU3A 1BSWA 5B5PA 5D7WA 1KUFA 4YEHA 3I7GA 1HV5A 3L0TA 2JIHA 3GBOA 2WO9A 1OZ9A 4PKWA 4H30A 1MMRA 3KEJA 1YCMA 3EWJA 1GKDA 3KECA 1PEXA 3HYGA 3EDGA 3S18A 3RTSA 1D5JA 3LEAA 3UVCA 2J0TA 3P24A 1BZSA 1EUBA 1SLNA 2X3AA 3HBVP 2HU6A 2MLSA 2USNA 3EHXA 3LP9A 3Q2HA 3I7IA 1JANA 3OYOA 1XFYA 1H71P 2OVXA 1GXDA 1XAXA 1GE6A 3KWVC 4H76A 1JKYA 1GO8P 3K7NA 4WK7A 3LGPA 1JIZA 1GE7A 3F18A 1K7IA 5B5OA 4H3XA 3EDIA 3DL1A 4FXYP 2OW0A 4ILWD 4PKUA 1OS2A 2DDFA 3DPEA 2I47A 3EDZA 4GR8A 2OXZA 4XCTA 1Q3AA 1IAGA 1Y93A 3F19A 1TVIA 5I2ZA 4XM8A 2W14A 1XM5A 1GO7P 1XFVA 3TS4A 3LE9A 2AYKA 3K7LA 2YIGA 1AKLA 2X3BA 1HTDA 3F16A 1RTGA 4WKIA 1JAQA 2J83A 2Z2DA 1BUVM 1R1JA 1UTZA 2D1OA 2Y6DA 1ZTQA 3O2XA 3EHYA 3USNA 1B3DA 2MQSA 1CIZA 4GF1A 1QUAA 4G9LA 1XURA 2OW9A 2WOAA 5JMYA 1G4KA 1IAEA 2E3XA 1C7KA 3C7XA 1KBCA 1BKCA 4I35A 2DW2A 3SHIA 1O0TA 1PWPA 1L6JA 2K9CA 5BPAA 1IAAA 2W15A 3LJGA 5L7FA 1Y0VA 1ATLA 1CGEA 2MZHA 3B2ZA 3LK8A 1PWUA 966CA 1HOVA 4JIJA 5CUHA 2JSDA 1RM8A 1UTTA 1B8YA 2JNPA 3KRYA 4L63A 1FM1A 4FXQA 3HY7A 3F15A 1JAPA 1CK7A 4XM6A 4PKSA 2DW0A 1GE5A 3ZUKA 1CGLA 4RT6B 2OZRA 2OW1A 1KUHA 4JQGA 2OXWA 2D1NA 4L19A 1ZXVA 3AYUA 4LL2A 3LKAA 3DNGA 1ASTA 1O0QA 1XFUA 1DMTA 3L0VA 1KUKA 1OM6A 3LIKA 2KRJA 1QIBA 2POJA 3LUMA 1QJJA 3NX7A 3LJTA 2W0DA 5CZMA 1XFXA 3DTIA 4Q1LA 1KUGA 3O64A 1K7GA 2TCLA 1R54A 1S4BP 1GENA 3V96B 1WNIA 2ERQA 4HMAA 1MMBA 1R1HA 2MZIA 4J4MA 1R1IA 1D8MA 2ERPA 1ND1A 1G12A 4A3WA 3DTKA 5BOTA 1BKCI 3BA0A 1AYKA 4IUWA 1SMPA 2SRTA 1Y8JA 1PWWA 2V4BA 2PJTA 1EB6A 2W12A 4DF9A 2FV9A 2MZEA 3LILA 3VI1A 1HFCA 4EFSA 4GUYA 3G5CA 1BIWA 1XUDA 3WV1A 5I43A 1MMPA 1ZP5A 3HDAP 3F1AA 3Q2GA 3V6NA 1JIWP 3OHOA 4IJOA 1PWQA 2Y6CA 1JH1A 2X3CA 1G9KA 3N2UA 3LUNA 1C8TA 1D7XA 1OM8A 2YB9A 3KMCA 1YP1A 1QICA 5LABA 4L7AA 5D2BA 3ZXHA 4AUOA 4IN9A 1GKCA 4R3VA 1BQQM 1FLSA 3LQ0A 4AXQA 1A85A 2EROA 2OY2A 4H49A 5I12A 1ZS0A 1I73A 1C3IA 1AF0A 4WF6A 1SATA 3WV3A 4ZR5A 1OM7A 1UMSA 2JXYA 3TSKA 2OI0A 3HBUP 2A8HA 1HXNA 3P1VA 1EAKA 1CAQA 1OO9A 5L79A 1BM6A 3F17A 1G49A 3DSLA 5I0LA 3RTTA 1JJ9A 4GR3A 1CXVA 4WKEA 4G0DA 1JAOA 2OW2A 1UEAA 4JP4A 5I4OA 1I76A 3VTGA 2MLRA 1RMZA 3EDHA 1XFZA 1IACA 2CLTA 4DD8A 2JT6A 4PKRA 1QJSA 3HDBA 2W13A 4AYKA 3HB2P 5D1TA 2RJPA 3TVCA 2DW1A 4HX3A 1J7NA 4PKVA 1ZVXA 3WV2A 4WZVA 3KMEA 4OEIA 4AIGA 3N2VA 1QJIA 4GQLA 2OY4A 1BQOA 5D1UA 3ELMA 4PKQA 1YQYA 3OHLA 1MMQA 3DWBA 1R55A 1ZXCA 1Z3JA 4GWNA 4FVLA 2OXUA 5H8XA 3CKIA 4FU4A 1CGFA 3KEKA 3LIRA 4H84A 2WO8A 5I3MA 1KUIA 2E2DA 3AIGA 1I1IP 3AYKA 2O36A 1QHUA 2O3EA 4DV8A 1BUDA 1G05A 4JPAA 1PWVA 4XM7A 4H82A 4QKZA 2XS4A 3DTEA 2RJQA 1K7QA 1SRPA 5CXAA
chains in the Genus database with same CATH topology
1CQRA 1D8FA 1HY7A 2FV5A 3U1RA 2CKIA 3B92A 5BOYA 4XBHA 1USNA 2YUFA 3LMCA 830CA 1HFSA 4H1QA 1ROSA 4CTHA 1IADA 1XFWA 2X7MA 2JT5A 3E8RA 4DPEA 2XS3A 1XUCA 1MNCA 3B8ZA 2OVZA 3LQBA 2QPJA 4H2EA 1YOUA 1DTHA 1QIAA 2AIGP 1KAPP 3HY9A 3KHIA 2DDYA 1OS9A 1IABA 4GWMA 3DPFA 4PKTA 3MA2A 4A7BA 4JA1A 1ITVA 2K2GA 2N8RA 4I03A 5D1SA 1OMJA 4L6TA 1BKCE 1UMTA 1JK3A 5D3CA 1SLMA 1A86A 456CA 3ZVSA 3G42A 3LJZA 4GR0A 3TT4A 4HSDA 4ON1A 1FBLA 2L0RA 1SU3A 1BSWA 5B5PA 5D7WA 1KUFA 4YEHA 3I7GA 1HV5A 3L0TA 2JIHA 3GBOA 2WO9A 4PKWA 4H30A 1MMRA 3KEJA 1YCMA 3EWJA 1GKDA 3KECA 1PEXA 3HYGA 3EDGA 3S18A 3RTSA 1D5JA 3LEAA 3UVCA 2J0TA 3P24A 1BZSA 1EUBA 1SLNA 2X3AA 3HBVP 2HU6A 2MLSA 2USNA 3EHXA 3LP9A 3Q2HA 3I7IA 1JANA 3OYOA 1XFYA 1H71P 2OVXA 1GXDA 1GE6A 3KWVC 4H76A 1JKYA 1GO8P 3K7NA 4WK7A 3LGPA 1JIZA 1GE7A 3F18A 1K7IA 5B5OA 4H3XA 3EDIA 3DL1A 4FXYP 2OW0A 4ILWD 4PKUA 1OS2A 2DDFA 3DPEA 2I47A 3EDZA 4GR8A 2OXZA 4XCTA 1Q3AA 1IAGA 1Y93A 3F19A 5I2ZA 4XM8A 2W14A 1GO7P 1XFVA 3TS4A 3LE9A 2AYKA 3K7LA 2YIGA 1AKLA 2X3BA 1HTDA 3F16A 1RTGA 4WKIA 1JAQA 2J83A 2Z2DA 1BUVM 1R1JA 1UTZA 2D1OA 2Y6DA 1ZTQA 3O2XA 3EHYA 3USNA 1B3DA 2MQSA 1CIZA 4GF1A 1QUAA 4G9LA 1XURA 2OW9A 2WOAA 5JMYA 1G4KA 1IAEA 2E3XA 1C7KA 3C7XA 1KBCA 1BKCA 4I35A 2DW2A 3SHIA 1O0TA 1PWPA 1L6JA 2K9CA 5BPAA 1IAAA 2W15A 3LJGA 5L7FA 1Y0VA 1ATLA 1CGEA 2MZHA 3B2ZA 3LK8A 1PWUA 966CA 1HOVA 4JIJA 5CUHA 2JSDA 1RM8A 1UTTA 1B8YA 2JNPA 3KRYA 4L63A 1FM1A 4FXQA 3HY7A 3F15A 1JAPA 1CK7A 4XM6A 4PKSA 2DW0A 1GE5A 3ZUKA 1CGLA 4RT6B 2OZRA 2OW1A 1KUHA 4JQGA 2OXWA 2D1NA 4L19A 1ZXVA 3AYUA 4LL2A 3LKAA 3DNGA 1ASTA 1O0QA 1XFUA 1DMTA 3L0VA 1KUKA 1OM6A 3LIKA 2KRJA 1QIBA 2POJA 3LUMA 1QJJA 3NX7A 3LJTA 2W0DA 5CZMA 1XFXA 3DTIA 4Q1LA 1KUGA 3O64A 1K7GA 2TCLA 1R54A 1S4BP 1GENA 3V96B 1WNIA 2ERQA 4HMAA 1MMBA 1R1HA 2MZIA 4J4MA 1R1IA 1D8MA 2ERPA 1ND1A 1G12A 4A3WA 3DTKA 5BOTA 1BKCI 3BA0A 1AYKA 4IUWA 1SMPA 2SRTA 1Y8JA 1PWWA 2V4BA 2PJTA 1EB6A 2W12A 4DF9A 2FV9A 2MZEA 3LILA 3VI1A 1HFCA 4EFSA 4GUYA 3G5CA 1BIWA 1XUDA 3WV1A 5I43A 1MMPA 1ZP5A 3HDAP 3F1AA 3Q2GA 3V6NA 1JIWP 3OHOA 4IJOA 1PWQA 2Y6CA 1JH1A 2X3CA 1G9KA 3N2UA 3LUNA 1C8TA 1D7XA 1OM8A 2YB9A 3KMCA 1YP1A 1QICA 5LABA 4L7AA 5D2BA 3ZXHA 4AUOA 4IN9A 1GKCA 4R3VA 1BQQM 1FLSA 3LQ0A 4AXQA 1A85A 2EROA 2OY2A 4H49A 5I12A 1ZS0A 1I73A 1C3IA 1AF0A 4WF6A 1SATA 3WV3A 4ZR5A 1OM7A 1UMSA 2JXYA 3TSKA 2OI0A 3HBUP 2A8HA 1HXNA 3P1VA 1EAKA 1CAQA 1OO9A 5L79A 1BM6A 3F17A 1G49A 3DSLA 5I0LA 3RTTA 1JJ9A 4GR3A 1CXVA 4WKEA 4G0DA 1JAOA 2OW2A 1UEAA 4JP4A 5I4OA 1I76A 3VTGA 2MLRA 1RMZA 3EDHA 1XFZA 1IACA 2CLTA 4DD8A 2JT6A 4PKRA 1QJSA 3HDBA 2W13A 4AYKA 3HB2P 5D1TA 2RJPA 3TVCA 2DW1A 4HX3A 1J7NA 4PKVA 1ZVXA 3WV2A 4WZVA 3KMEA 4OEIA 4AIGA 3N2VA 1QJIA 4GQLA 2OY4A 1BQOA 5D1UA 3ELMA 4PKQA 1YQYA 3OHLA 1MMQA 3DWBA 1R55A 1ZXCA 1Z3JA 4GWNA 4FVLA 2OXUA 5H8XA 3CKIA 4FU4A 1CGFA 3KEKA 3LIRA 4H84A 2WO8A 5I3MA 1KUIA 2E2DA 3AIGA 1I1IP 3AYKA 2O36A 1QHUA 2O3EA 4DV8A 1BUDA 1G05A 4JPAA 1PWVA 4XM7A 4H82A 4QKZA 2XS4A 3DTEA 2RJQA 1K7QA 1SRPA 5CXAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CQR A;  1D8F A;  1HY7 A;  2FV5 A;  3U1R A;  2CKI A;  3B92 A;  5BOY A;  4XBH A;  1USN A;  3LMC A;  830C A;  1HFS A;  4H1Q A;  1ROS A;  4CTH A;  1IAD A;  1XFW A;  2X7M A;  2JT5 A;  3E8R A;  4DPE A;  2XS3 A;  1XUC A;  1MNC A;  3B8Z A;  2OVZ A;  3LQB A;  2QPJ A;  4H2E A;  1YOU A;  1DTH A;  1QIA A;  2AIG P;  1KAP P;  3HY9 A;  3KHI A;  2DDY A;  1OS9 A;  1IAB A;  4GWM A;  3DPF A;  4PKT A;  3MA2 A;  4A7B A;  4JA1 A;  1ITV A;  2K2G A;  2N8R A;  4I03 A;  5D1S A;  1OMJ A;  4L6T A;  1BKC E;  1UMT A;  1JK3 A;  5D3C A;  1SLM A;  1A86 A;  456C A;  3ZVS A;  3G42 A;  3LJZ A;  4GR0 A;  3TT4 A;  4HSD A;  4ON1 A;  1FBL A;  2L0R A;  1SU3 A;  1BSW A;  5B5P A;  5D7W A;  1KUF A;  4YEH A;  3I7G A;  1HV5 A;  3L0T A;  2JIH A;  3GBO A;  2WO9 A;  4PKW A;  4H30 A;  1MMR A;  3KEJ A;  1YCM A;  3EWJ A;  1GKD A;  3KEC A;  1PEX A;  3HYG A;  3EDG A;  3S18 A;  3RTS A;  1D5J A;  3LEA A;  3UVC A;  2J0T A;  3P24 A;  1BZS A;  1EUB A;  1SLN A;  2X3A A;  3HBV P;  2HU6 A;  2MLS A;  2USN A;  3EHX A;  3LP9 A;  3Q2H A;  3I7I A;  1JAN A;  3OYO A;  1XFY A;  1H71 P;  2OVX A;  1GXD A;  1GE6 A;  3KWV C;  4H76 A;  1JKY A;  1GO8 P;  3K7N A;  4WK7 A;  3LGP A;  1JIZ A;  1GE7 A;  3F18 A;  1K7I A;  5B5O A;  4H3X A;  3EDI A;  3DL1 A;  4FXY P;  2OW0 A;  4ILW D;  4PKU A;  1OS2 A;  2DDF A;  3DPE A;  2I47 A;  3EDZ A;  4GR8 A;  2OXZ A;  4XCT A;  1Q3A A;  1IAG A;  1Y93 A;  3F19 A;  5I2Z A;  4XM8 A;  2W14 A;  1GO7 P;  1XFV A;  3TS4 A;  3LE9 A;  2AYK A;  3K7L A;  2YIG A;  1AKL A;  2X3B A;  1HTD A;  3F16 A;  1RTG A;  4WKI A;  1JAQ A;  2J83 A;  2Z2D A;  1BUV M;  1R1J A;  1UTZ A;  2D1O A;  2Y6D A;  1ZTQ A;  3O2X A;  3EHY A;  3USN A;  1B3D A;  2MQS A;  1CIZ A;  4GF1 A;  1QUA A;  4G9L A;  1XUR A;  2OW9 A;  2WOA A;  5JMY A;  1G4K A;  1IAE A;  2E3X A;  1C7K A;  3C7X A;  1KBC A;  1BKC A;  4I35 A;  2DW2 A;  3SHI A;  1O0T A;  1PWP A;  1L6J A;  2K9C A;  5BPA A;  1IAA A;  2W15 A;  3LJG A;  5L7F A;  1Y0V A;  1ATL A;  1CGE A;  2MZH A;  3B2Z A;  3LK8 A;  1PWU A;  966C A;  1HOV A;  4JIJ A;  5CUH A;  2JSD A;  1RM8 A;  1UTT A;  1B8Y A;  2JNP A;  3KRY A;  4L63 A;  1FM1 A;  4FXQ A;  3HY7 A;  3F15 A;  1JAP A;  1CK7 A;  4XM6 A;  4PKS A;  2DW0 A;  1GE5 A;  3ZUK A;  1CGL A;  4RT6 B;  2OZR A;  2OW1 A;  1KUH A;  4JQG A;  2OXW A;  2D1N A;  4L19 A;  1ZXV A;  3AYU A;  4LL2 A;  3LKA A;  3DNG A;  1AST A;  1O0Q A;  1XFU A;  1DMT A;  3L0V A;  1KUK A;  1OM6 A;  3LIK A;  2KRJ A;  1QIB A;  2POJ A;  3LUM A;  1QJJ A;  3NX7 A;  3LJT A;  2W0D A;  5CZM A;  1XFX A;  4Q1L A;  1KUG A;  3O64 A;  1K7G A;  2TCL A;  1R54 A;  1S4B P;  1GEN A;  3V96 B;  1WNI A;  2ERQ A;  4HMA A;  1MMB A;  1R1H A;  2MZI A;  4J4M A;  1R1I A;  1D8M A;  2ERP A;  1ND1 A;  1G12 A;  4A3W A;  5BOT A;  1BKC I;  3BA0 A;  1AYK A;  4IUW A;  1SMP A;  2SRT A;  1Y8J A;  1PWW A;  2V4B A;  2PJT A;  1EB6 A;  2W12 A;  4DF9 A;  2FV9 A;  2MZE A;  3LIL A;  3VI1 A;  1HFC A;  4EFS A;  4GUY A;  3G5C A;  1BIW A;  1XUD A;  3WV1 A;  5I43 A;  1MMP A;  1ZP5 A;  3HDA P;  3F1A A;  3Q2G A;  3V6N A;  1JIW P;  3OHO A;  4IJO A;  1PWQ A;  2Y6C A;  1JH1 A;  2X3C A;  1G9K A;  3N2U A;  3LUN A;  1C8T A;  1D7X A;  1OM8 A;  2YB9 A;  3KMC A;  1YP1 A;  1QIC A;  5LAB A;  5D2B A;  3ZXH A;  4AUO A;  4IN9 A;  1GKC A;  4R3V A;  1BQQ M;  1FLS A;  3LQ0 A;  4AXQ A;  1A85 A;  2ERO A;  2OY2 A;  4H49 A;  5I12 A;  1ZS0 A;  1I73 A;  1C3I A;  1AF0 A;  4WF6 A;  1SAT A;  3WV3 A;  4ZR5 A;  1OM7 A;  1UMS A;  2JXY A;  3TSK A;  2OI0 A;  3HBU P;  2A8H A;  1HXN A;  3P1V A;  1EAK A;  1CAQ A;  1OO9 A;  5L79 A;  1BM6 A;  3F17 A;  1G49 A;  3DSL A;  5I0L A;  3RTT A;  1JJ9 A;  4GR3 A;  1CXV A;  4WKE A;  4G0D A;  1JAO A;  2OW2 A;  1UEA A;  4JP4 A;  5I4O A;  1I76 A;  3VTG A;  2MLR A;  1RMZ A;  3EDH A;  1XFZ A;  1IAC A;  2CLT A;  4DD8 A;  2JT6 A;  4PKR A;  1QJS A;  3HDB A;  2W13 A;  4AYK A;  3HB2 P;  5D1T A;  2RJP A;  3TVC A;  2DW1 A;  4HX3 A;  1J7N A;  4PKV A;  1ZVX A;  3WV2 A;  4WZV A;  3KME A;  4OEI A;  4AIG A;  3N2V A;  1QJI A;  4GQL A;  2OY4 A;  1BQO A;  5D1U A;  3ELM A;  4PKQ A;  1YQY A;  3OHL A;  1MMQ A;  3DWB A;  1R55 A;  1ZXC A;  1Z3J A;  4GWN A;  4FVL A;  2OXU A;  5H8X A;  3CKI A;  4FU4 A;  1CGF A;  3KEK A;  3LIR A;  4H84 A;  2WO8 A;  5I3M A;  1KUI A;  2E2D A;  3AIG A;  1I1I P;  3AYK A;  2O36 A;  1QHU A;  2O3E A;  4DV8 A;  1BUD A;  1G05 A;  4JPA A;  1PWV A;  4XM7 A;  4H82 A;  4QKZ A;  2XS4 A;  2RJQ A;  1K7Q A;  1SRP A;  5CXA A; 
#chains in the Genus database with same CATH topology
 1CQR A;  1D8F A;  1HY7 A;  2FV5 A;  3U1R A;  2CKI A;  3B92 A;  5BOY A;  4XBH A;  1USN A;  2YUF A;  3LMC A;  830C A;  1HFS A;  4H1Q A;  1ROS A;  4CTH A;  1IAD A;  1XFW A;  2X7M A;  2JT5 A;  3E8R A;  4DPE A;  2XS3 A;  1XUC A;  1MNC A;  3B8Z A;  2OVZ A;  3LQB A;  2QPJ A;  4H2E A;  1YOU A;  1DTH A;  1QIA A;  2AIG P;  1KAP P;  3HY9 A;  3KHI A;  2DDY A;  1OS9 A;  1IAB A;  4GWM A;  3DPF A;  4PKT A;  3MA2 A;  4A7B A;  4JA1 A;  1ITV A;  2K2G A;  2N8R A;  4I03 A;  5D1S A;  1OMJ A;  4L6T A;  1BKC E;  1UMT A;  1JK3 A;  5D3C A;  1SLM A;  1A86 A;  456C A;  3ZVS A;  3G42 A;  3LJZ A;  4GR0 A;  3TT4 A;  4HSD A;  4ON1 A;  1FBL A;  2L0R A;  1SU3 A;  1BSW A;  5B5P A;  5D7W A;  1KUF A;  4YEH A;  3I7G A;  1HV5 A;  3L0T A;  2JIH A;  3GBO A;  2WO9 A;  1OZ9 A;  4PKW A;  4H30 A;  1MMR A;  3KEJ A;  1YCM A;  3EWJ A;  1GKD A;  3KEC A;  1PEX A;  3HYG A;  3EDG A;  3S18 A;  3RTS A;  1D5J A;  3LEA A;  3UVC A;  2J0T A;  3P24 A;  1BZS A;  1EUB A;  1SLN A;  2X3A A;  3HBV P;  2HU6 A;  2MLS A;  2USN A;  3EHX A;  3LP9 A;  3Q2H A;  3I7I A;  1JAN A;  3OYO A;  1XFY A;  1H71 P;  2OVX A;  1GXD A;  1XAX A;  1GE6 A;  3KWV C;  4H76 A;  1JKY A;  1GO8 P;  3K7N A;  4WK7 A;  3LGP A;  1JIZ A;  1GE7 A;  3F18 A;  1K7I A;  5B5O A;  4H3X A;  3EDI A;  3DL1 A;  4FXY P;  2OW0 A;  4ILW D;  4PKU A;  1OS2 A;  2DDF A;  3DPE A;  2I47 A;  3EDZ A;  4GR8 A;  2OXZ A;  4XCT A;  1Q3A A;  1IAG A;  1Y93 A;  3F19 A;  1TVI A;  5I2Z A;  4XM8 A;  2W14 A;  1XM5 A;  1GO7 P;  1XFV A;  3TS4 A;  3LE9 A;  2AYK A;  3K7L A;  2YIG A;  1AKL A;  2X3B A;  1HTD A;  3F16 A;  1RTG A;  4WKI A;  1JAQ A;  2J83 A;  2Z2D A;  1BUV M;  1R1J A;  1UTZ A;  2D1O A;  2Y6D A;  1ZTQ A;  3O2X A;  3EHY A;  3USN A;  1B3D A;  2MQS A;  1CIZ A;  4GF1 A;  1QUA A;  4G9L A;  1XUR A;  2OW9 A;  2WOA A;  5JMY A;  1G4K A;  1IAE A;  2E3X A;  1C7K A;  3C7X A;  1KBC A;  1BKC A;  4I35 A;  2DW2 A;  3SHI A;  1O0T A;  1PWP A;  1L6J A;  2K9C A;  5BPA A;  1IAA A;  2W15 A;  3LJG A;  5L7F A;  1Y0V A;  1ATL A;  1CGE A;  2MZH A;  3B2Z A;  3LK8 A;  1PWU A;  966C A;  1HOV A;  4JIJ A;  5CUH A;  2JSD A;  1RM8 A;  1UTT A;  1B8Y A;  2JNP A;  3KRY A;  4L63 A;  1FM1 A;  4FXQ A;  3HY7 A;  3F15 A;  1JAP A;  1CK7 A;  4XM6 A;  4PKS A;  2DW0 A;  1GE5 A;  3ZUK A;  1CGL A;  4RT6 B;  2OZR A;  2OW1 A;  1KUH A;  4JQG A;  2OXW A;  2D1N A;  4L19 A;  1ZXV A;  3AYU A;  4LL2 A;  3LKA A;  3DNG A;  1AST A;  1O0Q A;  1XFU A;  1DMT A;  3L0V A;  1KUK A;  1OM6 A;  3LIK A;  2KRJ A;  1QIB A;  2POJ A;  3LUM A;  1QJJ A;  3NX7 A;  3LJT A;  2W0D A;  5CZM A;  1XFX A;  3DTI A;  4Q1L A;  1KUG A;  3O64 A;  1K7G A;  2TCL A;  1R54 A;  1S4B P;  1GEN A;  3V96 B;  1WNI A;  2ERQ A;  4HMA A;  1MMB A;  1R1H A;  2MZI A;  4J4M A;  1R1I A;  1D8M A;  2ERP A;  1ND1 A;  1G12 A;  4A3W A;  3DTK A;  5BOT A;  1BKC I;  3BA0 A;  1AYK A;  4IUW A;  1SMP A;  2SRT A;  1Y8J A;  1PWW A;  2V4B A;  2PJT A;  1EB6 A;  2W12 A;  4DF9 A;  2FV9 A;  2MZE A;  3LIL A;  3VI1 A;  1HFC A;  4EFS A;  4GUY A;  3G5C A;  1BIW A;  1XUD A;  3WV1 A;  5I43 A;  1MMP A;  1ZP5 A;  3HDA P;  3F1A A;  3Q2G A;  3V6N A;  1JIW P;  3OHO A;  4IJO A;  1PWQ A;  2Y6C A;  1JH1 A;  2X3C A;  1G9K A;  3N2U A;  3LUN A;  1C8T A;  1D7X A;  1OM8 A;  2YB9 A;  3KMC A;  1YP1 A;  1QIC A;  5LAB A;  4L7A A;  5D2B A;  3ZXH A;  4AUO A;  4IN9 A;  1GKC A;  4R3V A;  1BQQ M;  1FLS A;  3LQ0 A;  4AXQ A;  1A85 A;  2ERO A;  2OY2 A;  4H49 A;  5I12 A;  1ZS0 A;  1I73 A;  1C3I A;  1AF0 A;  4WF6 A;  1SAT A;  3WV3 A;  4ZR5 A;  1OM7 A;  1UMS A;  2JXY A;  3TSK A;  2OI0 A;  3HBU P;  2A8H A;  1HXN A;  3P1V A;  1EAK A;  1CAQ A;  1OO9 A;  5L79 A;  1BM6 A;  3F17 A;  1G49 A;  3DSL A;  5I0L A;  3RTT A;  1JJ9 A;  4GR3 A;  1CXV A;  4WKE A;  4G0D A;  1JAO A;  2OW2 A;  1UEA A;  4JP4 A;  5I4O A;  1I76 A;  3VTG A;  2MLR A;  1RMZ A;  3EDH A;  1XFZ A;  1IAC A;  2CLT A;  4DD8 A;  2JT6 A;  4PKR A;  1QJS A;  3HDB A;  2W13 A;  4AYK A;  3HB2 P;  5D1T A;  2RJP A;  3TVC A;  2DW1 A;  4HX3 A;  1J7N A;  4PKV A;  1ZVX A;  3WV2 A;  4WZV A;  3KME A;  4OEI A;  4AIG A;  3N2V A;  1QJI A;  4GQL A;  2OY4 A;  1BQO A;  5D1U A;  3ELM A;  4PKQ A;  1YQY A;  3OHL A;  1MMQ A;  3DWB A;  1R55 A;  1ZXC A;  1Z3J A;  4GWN A;  4FVL A;  2OXU A;  5H8X A;  3CKI A;  4FU4 A;  1CGF A;  3KEK A;  3LIR A;  4H84 A;  2WO8 A;  5I3M A;  1KUI A;  2E2D A;  3AIG A;  1I1I P;  3AYK A;  2O36 A;  1QHU A;  2O3E A;  4DV8 A;  1BUD A;  1G05 A;  4JPA A;  1PWV A;  4XM7 A;  4H82 A;  4QKZ A;  2XS4 A;  3DTE A;  2RJQ A;  1K7Q A;  1SRP A;  5CXA A; 
#chains in the Genus database with same CATH homology
 1CQR A;  1D8F A;  1HY7 A;  2FV5 A;  3U1R A;  2CKI A;  3B92 A;  5BOY A;  4XBH A;  1USN A;  2YUF A;  3LMC A;  830C A;  1HFS A;  4H1Q A;  1ROS A;  4CTH A;  1IAD A;  1XFW A;  2X7M A;  2JT5 A;  3E8R A;  4DPE A;  2XS3 A;  1XUC A;  1MNC A;  3B8Z A;  2OVZ A;  3LQB A;  2QPJ A;  4H2E A;  1YOU A;  1DTH A;  1QIA A;  2AIG P;  1KAP P;  3HY9 A;  3KHI A;  2DDY A;  1OS9 A;  1IAB A;  4GWM A;  3DPF A;  4PKT A;  3MA2 A;  4A7B A;  4JA1 A;  1ITV A;  2K2G A;  2N8R A;  4I03 A;  5D1S A;  1OMJ A;  4L6T A;  1BKC E;  1UMT A;  1JK3 A;  5D3C A;  1SLM A;  1A86 A;  456C A;  3ZVS A;  3G42 A;  3LJZ A;  4GR0 A;  3TT4 A;  4HSD A;  4ON1 A;  1FBL A;  2L0R A;  1SU3 A;  1BSW A;  5B5P A;  5D7W A;  1KUF A;  4YEH A;  3I7G A;  1HV5 A;  3L0T A;  2JIH A;  3GBO A;  2WO9 A;  4PKW A;  4H30 A;  1MMR A;  3KEJ A;  1YCM A;  3EWJ A;  1GKD A;  3KEC A;  1PEX A;  3HYG A;  3EDG A;  3S18 A;  3RTS A;  1D5J A;  3LEA A;  3UVC A;  2J0T A;  3P24 A;  1BZS A;  1EUB A;  1SLN A;  2X3A A;  3HBV P;  2HU6 A;  2MLS A;  2USN A;  3EHX A;  3LP9 A;  3Q2H A;  3I7I A;  1JAN A;  3OYO A;  1XFY A;  1H71 P;  2OVX A;  1GXD A;  1GE6 A;  3KWV C;  4H76 A;  1JKY A;  1GO8 P;  3K7N A;  4WK7 A;  3LGP A;  1JIZ A;  1GE7 A;  3F18 A;  1K7I A;  5B5O A;  4H3X A;  3EDI A;  3DL1 A;  4FXY P;  2OW0 A;  4ILW D;  4PKU A;  1OS2 A;  2DDF A;  3DPE A;  2I47 A;  3EDZ A;  4GR8 A;  2OXZ A;  4XCT A;  1Q3A A;  1IAG A;  1Y93 A;  3F19 A;  5I2Z A;  4XM8 A;  2W14 A;  1GO7 P;  1XFV A;  3TS4 A;  3LE9 A;  2AYK A;  3K7L A;  2YIG A;  1AKL A;  2X3B A;  1HTD A;  3F16 A;  1RTG A;  4WKI A;  1JAQ A;  2J83 A;  2Z2D A;  1BUV M;  1R1J A;  1UTZ A;  2D1O A;  2Y6D A;  1ZTQ A;  3O2X A;  3EHY A;  3USN A;  1B3D A;  2MQS A;  1CIZ A;  4GF1 A;  1QUA A;  4G9L A;  1XUR A;  2OW9 A;  2WOA A;  5JMY A;  1G4K A;  1IAE A;  2E3X A;  1C7K A;  3C7X A;  1KBC A;  1BKC A;  4I35 A;  2DW2 A;  3SHI A;  1O0T A;  1PWP A;  1L6J A;  2K9C A;  5BPA A;  1IAA A;  2W15 A;  3LJG A;  5L7F A;  1Y0V A;  1ATL A;  1CGE A;  2MZH A;  3B2Z A;  3LK8 A;  1PWU A;  966C A;  1HOV A;  4JIJ A;  5CUH A;  2JSD A;  1RM8 A;  1UTT A;  1B8Y A;  2JNP A;  3KRY A;  4L63 A;  1FM1 A;  4FXQ A;  3HY7 A;  3F15 A;  1JAP A;  1CK7 A;  4XM6 A;  4PKS A;  2DW0 A;  1GE5 A;  3ZUK A;  1CGL A;  4RT6 B;  2OZR A;  2OW1 A;  1KUH A;  4JQG A;  2OXW A;  2D1N A;  4L19 A;  1ZXV A;  3AYU A;  4LL2 A;  3LKA A;  3DNG A;  1AST A;  1O0Q A;  1XFU A;  1DMT A;  3L0V A;  1KUK A;  1OM6 A;  3LIK A;  2KRJ A;  1QIB A;  2POJ A;  3LUM A;  1QJJ A;  3NX7 A;  3LJT A;  2W0D A;  5CZM A;  1XFX A;  3DTI A;  4Q1L A;  1KUG A;  3O64 A;  1K7G A;  2TCL A;  1R54 A;  1S4B P;  1GEN A;  3V96 B;  1WNI A;  2ERQ A;  4HMA A;  1MMB A;  1R1H A;  2MZI A;  4J4M A;  1R1I A;  1D8M A;  2ERP A;  1ND1 A;  1G12 A;  4A3W A;  3DTK A;  5BOT A;  1BKC I;  3BA0 A;  1AYK A;  4IUW A;  1SMP A;  2SRT A;  1Y8J A;  1PWW A;  2V4B A;  2PJT A;  1EB6 A;  2W12 A;  4DF9 A;  2FV9 A;  2MZE A;  3LIL A;  3VI1 A;  1HFC A;  4EFS A;  4GUY A;  3G5C A;  1BIW A;  1XUD A;  3WV1 A;  5I43 A;  1MMP A;  1ZP5 A;  3HDA P;  3F1A A;  3Q2G A;  3V6N A;  1JIW P;  3OHO A;  4IJO A;  1PWQ A;  2Y6C A;  1JH1 A;  2X3C A;  1G9K A;  3N2U A;  3LUN A;  1C8T A;  1D7X A;  1OM8 A;  2YB9 A;  3KMC A;  1YP1 A;  1QIC A;  5LAB A;  4L7A A;  5D2B A;  3ZXH A;  4AUO A;  4IN9 A;  1GKC A;  4R3V A;  1BQQ M;  1FLS A;  3LQ0 A;  4AXQ A;  1A85 A;  2ERO A;  2OY2 A;  4H49 A;  5I12 A;  1ZS0 A;  1I73 A;  1C3I A;  1AF0 A;  4WF6 A;  1SAT A;  3WV3 A;  4ZR5 A;  1OM7 A;  1UMS A;  2JXY A;  3TSK A;  2OI0 A;  3HBU P;  2A8H A;  1HXN A;  3P1V A;  1EAK A;  1CAQ A;  1OO9 A;  5L79 A;  1BM6 A;  3F17 A;  1G49 A;  3DSL A;  5I0L A;  3RTT A;  1JJ9 A;  4GR3 A;  1CXV A;  4WKE A;  4G0D A;  1JAO A;  2OW2 A;  1UEA A;  4JP4 A;  5I4O A;  1I76 A;  3VTG A;  2MLR A;  1RMZ A;  3EDH A;  1XFZ A;  1IAC A;  2CLT A;  4DD8 A;  2JT6 A;  4PKR A;  1QJS A;  3HDB A;  2W13 A;  4AYK A;  3HB2 P;  5D1T A;  2RJP A;  3TVC A;  2DW1 A;  4HX3 A;  1J7N A;  4PKV A;  1ZVX A;  3WV2 A;  4WZV A;  3KME A;  4OEI A;  4AIG A;  3N2V A;  1QJI A;  4GQL A;  2OY4 A;  1BQO A;  5D1U A;  3ELM A;  4PKQ A;  1YQY A;  3OHL A;  1MMQ A;  3DWB A;  1R55 A;  1ZXC A;  1Z3J A;  4GWN A;  4FVL A;  2OXU A;  5H8X A;  3CKI A;  4FU4 A;  1CGF A;  3KEK A;  3LIR A;  4H84 A;  2WO8 A;  5I3M A;  1KUI A;  2E2D A;  3AIG A;  1I1I P;  3AYK A;  2O36 A;  1QHU A;  2O3E A;  4DV8 A;  1BUD A;  1G05 A;  4JPA A;  1PWV A;  4XM7 A;  4H82 A;  4QKZ A;  2XS4 A;  3DTE A;  2RJQ A;  1K7Q A;  1SRP A;  5CXA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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